• 한국수산과학회지
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• 제19권5호
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• pp.502-508
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• 1986

해조류중 미역, 다시마, 곤피, 청각, 파래 및 김을 물, 메타놀, 핵산 및 에칠에테르로 추출한 엑스분의 항돌연변이 효과를 Salmonella typhimurium/microsome 계로 실험하였다. 물로 추출한 엑스분은 TrP-P-2와 aflatoxin $B_1$에 다소 효과가 있었고, 메타놀의 엑스분중 다시마, 곰피는 Trp-P-2에 효과가 있었으며, 메타놀 엑스분을 plate 당 1.0mg, 2.0mg 함유하는 모든 시료는 MeIQ와 aflatoxin $B_1$에 효과가 있었다. 에칠 에테르의 엑스분은 곰피와 청각이 매우 효과가 있었고, 특히 6종류의 해조류중 에칠 에테르의 엑스븐은 MeIQ와 aflatoxin $B_1$에 대하여 우수한 효과가 있었다.

• Preventive Nutrition and Food Science
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• 제6권1호
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• pp.57-61
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• 2001

Conjugated linoleic acid (CLA), when incorporated into mouse liver microsomal membranes, selectively inhibits the mutagenesis of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ). Nine-week old female ICR mice were given (p.o.) 0.1 mL olive oil alone (control), 0.1 mL olive oil plus 0.1 mL linoleic acid, or 0.1 mL olive oil plus 0.1 mL CLA, twice weekly for four weeks. The animals were then sacrificed and liver S-9 fractions were prepared. Activation of IQ for mutagenesis by the liver S-9 from CLA-treated mice was significantly reduced in comparison wit liver S-9 from control or linolic acid-treated mice. By contrast, the activation of 7,12-dimethylbenz[a] anthracene (DMBA) and benzo[a] pyrene (BP) was unaffected. Hence, CLA incorporated into phospholipids may selectively affect cytochrome P450 isozymes responsible for activating IQ, but not those which activate BP or DMBA. The addition of free CLA or the methyl esters of CLA, linoleic acid, or oleic acid, to control S-9 inhibited the activation of all three mutagens (IQ, BP, and DMBA).

• Archives of Pharmacal Research
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• 제21권4호
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• pp.363-369
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• 1998

Glutathione S-transferase placental form (GST-P) positive foci development and its expression in liver exposed by nongenotoxic carcinogens phenobarbital (PB) and clofibrate (CF), and genotoxic carcinogen 2-amino-3-methylimidazo[4,5-f] quinoline (IQ) were investigated as a measure of carcinogenic potential of these chemicals. Male F344 rats were initially given a single intraperitioneal injection of diethyinitrosamine (200 mg/kg), and 2 weeks later, animals were fed diets containing 0.03% IQ or 0.5% CF or 0.05% PB or basal diet as a control for 6 weeks. All rats were subjected to two-thirds partial hepatectomy (PH) at week 3. Sequential sacrifice of rats was performed at 8 weeks or 52 weeks, and liver tissues were examined for immunohistochemical staining of GST-P positive foci. The numbers (No./$cm^2$) and areas ($mm^2$/ $cm^2$) of GST-P positive foci were increased by IQ or PB, but were decreased by CF compare to the control. Consistent with the development of GST-P positive foci, a time-related increase in the expression of GST-P mRNA was found in the rats treated with IQ, whereas CF decreased it. The incidence of hepatocellular carcinoma at 52 weeks was increased by all three chemicals. These results show that PB and IQ induced GST-P positive foci, but the peroxisome proliferator CF did not, which suggest that the prediction of carcinogenic potency based on the development of prenoplastic foci may cause false negative in a particular category compounds like peroxisome proliferators.

• 아동학회지
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• 제31권1호
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• pp.113-124
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• 2010

This study analyzed the relationships between home environment, child characteristics and school readiness. In particular, it examined the influence of home environment and child characteristics upon children's school readiness with a focus on attitudes towards and other socio-emotional aspects. 57 children's characteristics, including such items as IQ performance and demographic variables were obtained by means of both individual testing of the child and through a questionnaire given to their parents. Relative levels of school readiness were then rated by teachers. Pearson correlations, and a multiple regression analysis were carried out using the SPSS Win 12.0 program. Our results indicated that (1) school readiness was positively related with mother's job, HOME, the ages of the children, Performance IQ, and Total IQ. (2) The level of the other's education, her job and the child's age was found to significantly predict the level of school readiness.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2008년도 하계종합학술대회
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• pp.399-400
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• 2008

This paper presents a new architecture of unified IP/IT/IQ/MC circuit for H.264 decoder based on operation sharing and efficient scheduling. The resultant circuit based on the proposed architecture uses only 12 adders and 1 multiplier. We further reduced the circuit size by sharing buffers. Our circuit consists of 47,810 gates and operates at the maximum operating frequency of 117MHz with 130nm standard cells.

• 전력전자학회:학술대회논문집
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• 전력전자학회 1998년도 Proceedings ICPE 98 1998 International Conference on Power Electronics
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• pp.876-881
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• 1998

The compensation strategy of shunt active power filters is one of the most important link that determine its compensation characteristics. In this paper, a new interpretation of the instantaneous reactive power theory in three-phase circuits was proposed. A compensation strategy (ip, iq mode) was introduced on the basis of the new interpretation. This compensation strategy was compared with other two compensation strategies(P, q mode and UPF mode). When source voltage is distorted, a sinusoidal, the three compensation strategies are equivalent to each other. When source voltage is distorted, a sinusoidal source current may result only by using ip, iq mode. This is the advantage of ip, iq mode. The result is verified by simulation.

• 전기전자학회논문지
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• 제14권2호
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• pp.76-81
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• 2010

모바일 CPU의 성능이 향상됨에 따라 전용 하드웨어의 필요성이 줄어 들고 있다. 그러나 아직까지 모바일 CPU의 성능은 한계가 있다. 이러한 제약 조건을 병렬처리와 실수 연산이 뛰어난 GP-GPU(General-Purpose computing on Graphics Processing Units)를 이용함으로써 다른 전용 하드웨어의 추가 없이 성능을 향상 시킬 수 있다. 본 논문에서는 모바일 환경에 적합하게 설계된 GP-GPU를 이용하여 H.264 디코더의 Inverse Quantization, Inverse DCT, Color Space Conversion 모듈을 구현하였다. G-PGPU를 이용한 전체 시스템 동작 시 40%의 성능 향상이 있었다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2010년도 춘계학술대회
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• pp.162-164
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• 2010

ITU-T와 ISO가 공동 제정한 동영상 압축 표준 H.264는 기존 동영상 압축 표준에 비해 높은 압축성능과 유연성을 가진다. 본 논문에서는 병렬 처리에 효과적인 GPGPU(General-Purpose computing on Graphics Processing Units)를 이용하여 H.264/AVC 복호화 알고리즘에서 병렬 처리가 가능한 IQ/IDCT (Inverse Quantization/ Inverse Discrete Cosine Transform) 연산을 고속으로 수행하기 위한 효율적인 구조와 방법을 제안한다.

• 한국환경성돌연변이발암원학회지
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• 제23권3호
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• pp.94-98
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• 2003

Quercetin and naringenin are representative flavonoids that not only exert anti estrogenic, cholesterol-lowering and antioxidant activities but also can modulate the metabolism of many xenobiotics. The activity of the specific form(s) of CYP450 is likely to be a major determinant of susceptibility to chemically induced carcinogenesis between which varies among between individuals due to different dietary habits as well as genetic characteristics. People consume cooked meat or fish together with various vegetables containing substantial amounts of quercetin and naringenin that can modify the enzyme activity of CYP1A2 to stimulate or to inhibit the mutagenic activities of HCAs. Heterocyclic amines (HCAs) produced by cooking meat products at high temperatures are promutagens that are activated by cytochrome P450 (CYP) lA2. Using a newly developed Salmonella typhimurium TA1538/1A2bc-b5 strain, we tested the effect of quercetin and naringenin on the mutagenicity of 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ). TA1538/1A2bc-b5 bears two plasmids, one expressing human CYP1A2 and NADPH-P450 reductase (NPR), and the other plasmid which expresses human cytochrome b5 (cyp b5). TA1538/1A2bc-b5 cells showed high activities of 7-ethoxyresorufin O-deethylase (EROD) and methoxyresorufin O-demethylase (MROD) associated with CYP1A2 and are very sensitive to mutagenesis induced by several HCAs. MeIQ was found to be the strongest mutagen among the HCAs tested in this system. Mutagenicity of MeIQ was enhanced 50 and 42% by quercetin at 0.1 and 1 mM, respectively, but suppressed 82% and 96% at 50 mM and 100 mM. Naringenin also increased the MeIQ-induced mutation about 37% and 22% at 0.1 and 1 mM, but suppressed it 32% and 63% at 50 mM and 100 mM concentrations, respectively, in TA 1538/1A2bc-b5 cells. Thus, they stimulated the MeIQ induced mutation at low concentrations, but strongly suppressed it at high concentrations. This biphasic effect of flavonoids was due to the stimulation or the inhibition of CYP1A2 activity in a dose-dependent manner judging by the activities of EROD or MROD in the Salmonella cells. Collectively, it is likely that the biphasic effects of quercetin and naringenin on the MeIQ-induced mutagenesis in S. typhimurium TA1538/CYP1A2bc-b5 were due to their differential modification of the CYP1A2 activity in these cells.

• 한국전자파학회논문지
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• 제20권1호
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• pp.21-28
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• 2009

DFT(Discrete Fourier Transform) 확산 방식의 OFDM(Orthogonal Frequency Division Multiplexing) 통신 시스템은 PAPR(Peak-to-Average Power Ratio) 저감에 매우 효과적인 시스템이며, 3GPP LTE($3^{rd}$ Generation Partnership Project Long Term Evolution)의 상향 링크에 SC-FDMA(Single Carrier-Frequency Division Multiple Access)에 사용된다. SC-FDMA는 일반적으로 OFDM 시스템보다 위상잡음과 직교 불균형으로 인한 ICI(Inter-Carrier Interference)에서 더 성능 열화가 발생하며, 등화기에 심각한 영향을 미친다. 그러므로 본 논문에서는 상향 링크에서 신호 전송 시 발생하는 위상잡음과 직교 불균형(IQ Imbalance: In-phase/Quadrature Imbalance), 그리고 전력 증폭기(HPA: High Power Amplifier)의 백-오프 특성에 따른 영향을 분석하고, ICI 성분을 제거할 수 있는 효과적인 등화 알고리듬을 제시한다. 제안된 등화기는 FDE(Frequency Domain Equalizer) 방식을 기반으로 설계하였으며, 기존의 PNS(Phase Noise Suppression) 알고리듬을 FDE에 사용될 수 있도록 수정하고 개선하여 위상 잡음과 직교 불균형으로 인한 ICI를 보상한다. 시뮬레이션 결과를 통하여 back-off 5.5 dB 상태에서 위상 잡음 $0.06\;rad^2$, 위상 에러 5도, 진폭 에러 0.005인 경우, 위상 잡음과 직교 불균형을 보상하여 SNR=14 dB 정도에서 $BER=10^{-4}$의 성능을 만족할 수 있다.