• 제목/요약/키워드: INK

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비소세포폐암과 염증성 폐질환에서 가래와 혈액 및 조직에서 p16INK4a Promoter 과메틸화 (p16INK4a Promoter Hypermethylation in Sputum, Blood, and Tissue from Non-Small Cell Lung Cancer and Pulmonary Inflammation)

  • 김정표;김경미;권순석;김영균;김관형;문화식;송정섭;박성학;안중현
    • Tuberculosis and Respiratory Diseases
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    • 제60권2호
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    • pp.160-170
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    • 2006
  • 연구배경 : 종양억제유전자인 $p16^{INK4a}$는 promoter region의 과메틸화로 인해 비소세포폐암의 발생에 관여하는 것으로 잘 알려져 있지만 폐암의 진단 방법으로 사용할 수 있는지는 아직까지 명확하지 않다. 이에 저자들은 비소세포폐암과 염증성 폐질환 환자의 가래와 혈액 및 조직에서 $p16^{INK4a}$ 메틸화의 발현 정도와 발현 일치 정도를 알아보고자 하였다. 방 법 : 폐종양을 주소로 내원하여 혈액, 가래 및 조직 검사를 시행한 후 최종적으로 비소세포폐암(18명)과 염증성 폐질환(5명) 진단을 받은 23명을 대상으로 하였다. 각 표본에서 DNA를 추출한 후 메틸화 특이성 중합효소연쇄반응법을 이용하여 $p16^{INK4a}$ promoter region의 메틸화 양상을 비교 분석하였다. 결 과 : 혈액에서는 비소세포폐암 그룹(88.9%, 18명중 16명)이 염증성 폐질환 그룹(20.0%, 5명중 1명)보다 $p16^{INK4a}$ 메틸화 발현이 증가하였으며(P=0.008), 가래에서는 비소세포폐암 그룹(12명중 10명)과 염증성 폐질환 그룹(5명중 4명)의 발현 차이는 없었다(P=1.00). 조직은 비소세포폐암 그룹에서 8명중 6명(75.0%)이 $p16^{INK4a}$ 메틸화가 나타났다. 혈액, 가래 및 조직에서 $p16^{INK4a}$ 메틸화의 발현 일치율은 7명 중 4명이 일치한 57.1%를 보였다. 결 론 : 비소세포폐암 그룹에서 염증성 폐질환 그룹보다 혈액의 $p16^{INK4a}$ 메틸화가 증가하였고 조직과의 일치율도 높았다. 따라서 폐암이 의심되는 고 위험 인자가 있는 환자에서 혈액의$p16^{INK4a}$ 과메틸화는 비소세포폐암과 염증성 폐질환을 감별하는데 유용하게 사용될 수 있을 것으로 생각한다.

잉크에 부분적으로 잠겨 회전하는 롤 주위의 액막 유동 해석 (The analysis of film flow around rotating roller partially immersed in ink)

  • 유승환;강수진;이관수
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2007년도 춘계학술대회B
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    • pp.2279-2284
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    • 2007
  • This study is intended to analyze the effect of thin ink-film thickness around rotating printing roll on the printing quality in the gravure printing process which is used for making electronics circuit like a RFID tag with a conductive ink. The present work numerically estimates the film thickness around rotating roller partially immersed in ink, for which the volume of fluid (VOF) method was adopted to figure out the film formation process around rotating roller. Parameter studies were performed to compare the effect of ink viscosity, surface tension, roller rotating speed, immersed angle on the film thickness. The result indicates that the film thickness has a strong dependency on the fluid viscosity, while the surface tension has negligible effect.

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잉크젯 토출 특성 평가 장치 개발 (Development of a Test Stand for Measuring Ink Jetting Performance)

  • 권계시
    • 한국정밀공학회지
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    • 제25권8호
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    • pp.45-50
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    • 2008
  • An ink jetting measurement system has been developed such that the velocity as well as the volume of ink droplets can be measured. In order to measure the ink droplet, a strobe LED light was synchronized to the droplet firing signal in order to obtain frozen droplet images. Then, a LabVIEW based software was developed for the analysis of the droplet image. For the efficient droplet analysis, a user generated rectangular shaped ROI (Region of Interest) was used. By using ROI, the ink droplet image can be easily isolated from the other structures such as printhead and the processing area can be minimized.

Malignant Melanoma Arising in Red Tattoo Ink

  • Joyce, Cormac Weekes;Duff, Gerald;McKenna, Dermot;Regan, Padraic James
    • Archives of Plastic Surgery
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    • 제42권4호
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    • pp.475-477
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    • 2015
  • We report the case of a 33-year-old male who presented with a malignant melanoma on his anterior chest wall. The lesion was only found in the red ink pigment of the tattoo, as were several in-transit dermal metastases. Possible explanations include a pre-existing lesion which was seeded with red ink or the possibility of the red ink causing an inflammatory reaction leading to malignant transformation. This is the first reported case of a melanoma developing in the red ink pigment of a multi-colored tattoo.

유기 EL 디스플레이 생산 공정을 위한 잉크젯헤드 제어시스템 구현 (Development of Ink-Jet Head Controller for Electro-Luminescence Display)

  • 정성욱;이희숭;유정래;박재석;정명진
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2004년도 학술대회 논문집 정보 및 제어부문
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    • pp.623-625
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    • 2004
  • In Electro-Luminescence Display making process, it is necessary to do high molecule patterning effectively. Recently, one of the most effective way is the patterning method using Ink-Jet head controller. To maximize the effect, it is needed to control each channel of Ink-Jet head and develop that controller. Thus, we implement the Ink-Jet Head Controller which can control the parameters of 128 fire pulses independently, improve the accuracy of patterns more than 100 times previous ones, and apply random patterns.

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플라스틱 필름에 대한 유기 용매의 전이 특성에 관한 연구 (Studies on the Migration behavior of various Printing Ink solvents of plastic films)

  • 안덕준
    • 한국포장학회지
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    • 제6권1호
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    • pp.19-23
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    • 2000
  • The increasing use of plastics in food packaging materials has led to the issue of food-packaging mutual interactions from residues in the plastics. Plastic films are commonly printed by using solvent-based ink to decorate the packaged food for consumer attention. However, the residual solvents can not be completely removed and they can migrate into the contained food which lead to undesirable off-flavors. Partitioning (Kp) of printing ink solvents was studied in two types of plastic films with different chemical structure and polarity. At $25^{\circ}C$, Kp of toluene is higher than that of isopropanol in PP, but isopropanol showed higher Kp value than toluene in EVOH. This showed that polarity had a significant effect on the partitioning of printing ink solvents into the plastic films. Printing solvents had a higher affinity to the polymer with similar polarity than it did to the different one.

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Rosin변성 phenol수지의 분자량 변화에 따른 평판인쇄 잉크의 물성변화에 관한 연구 (The Effect of Changing Molecular Weight of Rosin Modified Phenol Resin on Physical Properties of Litho Printing Inks)

  • 김성빈
    • 한국인쇄학회지
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    • 제12권1호
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    • pp.145-157
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    • 1994
  • Litho printing ink vehicles based on rosin modified phenolic are faster drying, have better durability, are harder and glosser and have greater resistance to water than ones based on ester gums. Ink-Water balance and rheological properties are important in litho printing process. These physical properties is concerned with molecular weight of Resin to use vehicle. So this paper was studied about the effects of changing molecular weight of Rosin modified phenolic on surface tension, viscosity, pseudoplasticity and printability of Litho Inks. The results were as follows. 1) The surface tension of model inks depended on the molecular \veight of the resin : Dispersion componnent of ink increase but non dispersion component decrease as molecular weight of Resin increase. 2) Water pick-up of litho ink is more fast balance, using low molecular weight of Resin. 3) Viscosity, Yield value and Newtonian value of model inks increase as molecular weight of Resin increase. 4) The litho ink prepared with the modified phenolic of which molecular weight is about 20000 showed the highest printing density and gloss.

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축임물의 성분에 따른 평판인쇄잉크의 유화량에 미치는 영향 (Effect of dampening agents on emulsification for lithography ink)

  • 권대환;김성빈;조진우
    • 한국인쇄학회:학술대회논문집
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    • 한국인쇄학회 2001년도 국제학술발표회
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    • pp.135-140
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    • 2001
  • Laboratory test method which determines the emulsification rate of dampening solution and ink has been described In lithography using the mutual repellence of oil and water, the emulsification is produced by dispersion of dampening water and ink because of the printing pressure on a practical press. Rheological properties of Ink-Water balance are the important factors in lithographic printing. The emulsification theory and laboratory test method deduced from Surland and Kim. It is shown that the emulfisication curves relate to the rates of change in the emulsifide ink\`s flow properties, to the shear stability of the emulsion formed To study on the factors determining the emulsion velocity, we have measured water pickup and calculated emulsification velocity constant \`k\` and activation energy.

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인쇄과정에서 코팅 용지의 국부적인 표면강도 변화에 관한 연구 (The Local Surface Strength Variation of Coated Papers during Printing)

  • 윤종태
    • 한국인쇄학회지
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    • 제22권2호
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    • pp.101-110
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    • 2004
  • The local surface strength variation of coated papers were measured at various speeds on a number of coated paper samples to study the effects of speed and ink tack on coating pick. Coating pick phenomenon is observed in an ink transfer variation curve as a decrease in the slope of the curve. On the other hand, it causes an actual decrease in net ink transfer to paper with an increase in speed. The effect of speed on coating pick depends on ink tack, ink film thickness and surface properties of coating layer formation of paper. A novel device to measure the surface strength can rate the coating paper in a different order. Comparison are made between dry test of coating paper pick and wet coating pick test of printing in IGT printability tester. Coating formulation is the main key to prevent from coating pick. The binder level increases, the coating pick and the slop decrease. The piling on blanket in printing is a problem when the coating pick is occur on a local area rather than average surface strength of coated papers.

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