• 대한의생명과학회지
• /
• 제7권3호
• /
• pp.127-131
• /
• 2001

This study was undertaken to examine the effect of amino acids on anoxia-induced cell injury in rabbit renal cortical slices. In order to induce anoxic cell injury, slices were exposed to a 100% $N_2$ atmosphere and control slices were exposed to 100% $O^2$. Irreversible cell injury was estimated by measuring lactate dehydrogenase (LDH) release and alterations in renal cell function were examined by measuring p-aminohippurate (PAH) uptake. Anoxia caused the increase in LDH release in a time-dependent manner. Glycine and glutathione almost completely prevented anoxia-induced LDH release. Of amino acids tested, glycine and alanine exerted the protective effect against anoxia-induced cell injury. However, asparagine with amide side chain, leucine and valine with hydrocarbon side chain, and basic amino acids (lysine, histidine, and arginine) were not effective. Anoxia-induced inhibition of PAM uptake was prevented by glycine. ATP content was decreased by anoxia, which was not affected by glycine. Anoxia-induced depletion of glutathione was significantly prevented by glycine. These results suggest that neutral amino acids with simple structure exert the Protective effect against anoxia-induced cell injury the involvement of specific interaction of amino acids and cell structure.

• 생물정신의학
• /
• 제7권1호
• /
• pp.55-63
• /
• 2000

Avariety of symptoms can occur following traumatic brain injury(TBI) or other types of acquired brain injury. These symptoms can include problems with short-term memory, attention, planning, problem solving, impulsivity, disinhibition, poor motivation, and other behavioral and cognitive deficit. These symptoms may respond to certain drugs, such as dopaminergic agents. Amantadine may protect patients from secondary neuronal damage after brain injury as a effect of NMDA receptor antagonists and may improve functioning of brain-injured patients as a dopaminergic agonist. Clinically, based on current evidence, amantadine may provide a potentially effective, safe, and inexpensive option for treating the cognitive, mood, and behavioral disorders of individuals with brain injury. The rationales for using amantadine are discussed, and pertinent literatures are reviewed.

• 한국자동차공학회논문집
• /
• 제18권2호
• /
• pp.104-113
• /
• 2010

Domestic insurance claims were statistically investigated to analyze the elderly driver's accident patterns and injury types in side impact crashes. Medical treatment records and accident vehicle damage photos have been surveyed for 5,419 cases. The results of our statistical analysis showed that the thorax injury risk of the elderly drive group is 8.8 and 4.0 times higher than that of the young and middle age group respectively. Diagnosis showed that most thorax injuries were caused by rib fracture. The head injury risk of the elderly female driver group seemed to be higher than that of the younger female driver group, however, statistical test has not been conducted because of the lack of number of samples for elderly female accident.

• 대한족부족관절학회지
• /
• 제15권4호
• /
• pp.243-246
• /
• 2011

Lisfranc injury is complex and difficult to treat. Making the correct diagnosis and achieving an anatomical reduction are important factors in regard to achieving a favorable outcome with this injury. We describe a new technique that we have found to be useful for stabilizing Lisfranc injury. This method is relatively fast and simple, and it provides non-rigid fixation. Also, it eliminates the need for implant removal. To date, we have achieved predictable results for stabilizing and treating this injury with the use of a $TightRope^{TM}$ Device, instead of traditional interfragmental screw fixation. In this report, we describe a case in which this method was used with satisfactory short-term results.

• Journal of Trauma and Injury
• /
• 제28권2호
• /
• pp.79-82
• /
• 2015

Simple rib fracture is one of most common injury after blunt thoracic trauma found in approximately 7% to 40% of cases. Delayed traumatic diaphragmatic injury with massive hemothorax after rib fracture is rare but a potentially life-threatening condition. We present a rare case of a 79-year-old male with delayed diaphragmatic injury with massive hemothorax due to fracture of the lower ribs. Under thoracoscopy, hemothorax was evacuated, diaphragmatic rupture was identified and repaired, and the lower ribs were fixed with metal plate (s). Although simple lower rib fractures may be the only clinical finding, close observation and monitoring are required because of the possibility of diaphragmatic and/or intraabdominal organ injury.

• Journal of Trauma and Injury
• /
• 제29권2호
• /
• pp.51-55
• /
• 2016

Isolated injury to the pancreas after abdominal trauma is uncommon, and a delay in diagnosis and treatment can increase the morbidity and mortality. Therapeutic decisions with respect to pancreatic trauma are usually made based on the site of injury and the status of the pancreatic ductal system. In this report, we describe the surgical management of pancreatic head transection as an isolated injury following blunt abdominal trauma. A 55-year-old man presented with epigastric pain that radiated to the back. Abdominal computed tomography revealed a hematoma in the pancreatic head and upstream dilatation of the main pancreatic duct. Endoscopic retrograde cholangiopancreatography showed complete disruption of and contrast leakage from the main pancreatic duct in the pancreatic head region with a nonenhanced upstream duct. Emergency pancreaticoduodenectomy was successfully performed, and the patient was discharged on postoperative day 9 without any complications.

• 한국안전학회지
• /
• 제20권1호
• /
• pp.153-157
• /
• 2005

The injury accidents in fishing vessels account for $67.2\%$ of all marine injury casualties$(1997\~2001)$ and is on an increasing trend every year. Also, it is remarkable for the injury accidents to be basically caused by human errors. This study aims to investigate the human error of injury accidents in fishing vessels and presents the injury preventing program in them. Human errors were analysed by the methods such as SHELL & Reason Hybrid Model, GEMS Model adopted by International Maritime Organization(IMO). Based on the analysis, the following propositions were made to reduce the fishing vessels accidents by human errors : improvement of hazard awareness and quality of personnel, establishment of safety management system, and enforcement of vessels inspection.

• 한국자동차공학회논문집
• /
• 제19권3호
• /
• pp.9-15
• /
• 2011

This study analyzed contributing factors affecting leg injury severity in pedestrian-vehicle crashes. A Binary Logistic Regression (BLR) method was used to identify the factors. Independent variables include characteristics for pedestrian, vehicle, road, and environmental conditions. The leg injury severity is classified into two classes, which are dependent variables in this study, such as 'severe' and 'minor' injuries. Pedestrian age, collision speed, and the height of vehicle were identified as significant factors for the leg injury. The probabilistic outcome of predicting leg injury severity can be effectively used in not only deriving pedestrian-related safety policies but also developing advanced vehicular technologies for pedestrian protection.

• 한국철도학회:학술대회논문집
• /
• 한국철도학회 2008년도 춘계학술대회 논문집
• /
• pp.1236-1245
• /
• 2008

Recently the Emergency Response is very important issue in Korea because there are lots of damage of people and property. In this paper, we have studied person's injury related to emergency action to minimize the damage on KTX. We defined what Activities of the emergency response workers should take when the Person's injury occurs on the railway. This has been possible through the development of the scenario that is focused on the person's injury accident. We considered all kinds of environment of KTX related to emergency action of person's injury accidents. Finally, we developed the role and responsibility of emergency response workers against KTX person's injury accidents.

• 대한안전경영과학회지
• /
• 제4권3호
• /
• pp.1-11
• /
• 2002

It has been Management for stabilize Enterprise-Management for Economic demand for to Productivity, Automation, customer satisfaction, Especially Semiconductor-Industry has been, potential-risk in working to factory to machine equipment, all kinds of utility, gas, chemical, electronic, Fire. This study of basic-purpose has Research Different From as Follow to analysis and Solution For semiconductor product Factory of a actual point Data and specific-gravity to Relation for company-Injury. 1. It has been try to Injury-Tendency and cause-Analysis for our County-Manufacture-Occupation. 2, Semiconductor Injury of Actual-condition in Enforcement for problem and Analysis that Injury Problem has occupated it Submitted to Solution for ordinary Injury theory View to point Solve at for New Model has applicated to that nilem for processed to Solution.