• 제목/요약/키워드: IL-1ra

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초기청소년의 사회참여가 학교생활 적응에 미치는 영향과 공동체의식의 매개효과 (The Influence of Social Participation on School Adjustment in Early Adolescents: Mediating Effects of a Sense of Community)

  • 김명일;고아라;임경미
    • 한국지역사회생활과학회지
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    • 제24권1호
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    • pp.71-84
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    • 2013
  • In this study we examine the relationship between the social participation in the early adolescents and school adjustment as well as the mediating effects of a sense of community. Findings provide ways of intervention that can increase a youth's school life. Based on samples of 2,351 first grade middle school students from the data in the 'Korea Youth Panel Survey' administered by the National Youth Policy Institute, we analysed the correlation among the variables. The results are as follows. First, the social participation of youths showed a major influence on school adjustment, and was identified as: the more the students participate in social activities, the better the students get adjusted to school. Second, the social participation has a significant effect on sense of community. In other words, the more the students participate in social activities, the more the students get a sense of community. Third, a sense of community mediated the process of social participation on school adjustment. These findings indicate that in order to increase a youth's school adjustment, a promotion of social participation and an effort to increase a sense of community are required. The implications of these findings suggest that by intervening social welfare and policy, can improve the integrity of a youth's school life.

단백체학을 이용한 인삼의 에너지대사 및 항생효과 관련 성분에 대한 연구 (Proteomics-based Identification of Components in the Adventitious Roots of Panax Ginseng C. A. Mayer related to Energy Metabolism and Antibiotic Effects)

  • 조진형;전영주;이라함;심정현;채정일
    • 한국유기농업학회지
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    • 제22권1호
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    • pp.167-182
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    • 2014
  • Korean Panax ginseng C. A. Meyer (P. ginseng) is a well-known and one of the most important tonic herbs used in traditional Korean medicine. The pharmacological effects of P. ginseng have been reported by many researchers. Nevertheless, little is known between the mechanism of action and the active compounds. In this study, we performed a comprehensive proteomic analysis and protein categorization in order to understand the physiological characteristics of the major components in the adventitious roots of P. ginseng. Whole proteins extracted from the cultured adventitious roots of P. ginseng were separated by two-dimensional polyacrylamide gel electrophoresis (2-DE). Among the 1000 spots which were detected by silver staining, 113 spots were labeled and identified by matrix-assisted laser desorption/ionization-time of flight-mass spectrometry (MALDI-TOF MS). Our results showed that 40 proteins were identified among the 113 spots, with a hit ratio of 35.3%. A number of proteins identified on the 2-DE gels (30%; 16 spots) were involved in energy metabolism. These proteomic data will be helpful to better understand the physiological and pharmacological effects of P. ginseng.

Rocatec system이 Zir-ceram과 간접복합수지간의 전단결합강도에 미치는 영향 (Effect of Rocatec system on Shear Bond Strength between Zir-Ceram and Sinfony Indirect Composite Resin)

  • 김동일;김부섭;정인성
    • 대한치과기공학회지
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    • 제30권2호
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    • pp.23-29
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    • 2008
  • The purpose of this study is to evaluate possibility of using indirect composite resin instead of porcelain through the measurement of shear bond strength between zirconia core and indirect composite resin under treatment of $Rocatec^{TM}$ system for improving the adhesion of indirect composite resin. 20 cylindrical zirconia core specimens were divided into 2 groups, according to zirconia surface treatment and attached materials: 1) treated with sandblast and attached with indirect composite resin, 2) treated with sandblast + $Rocatec^{TM}$ system and attached with indirect composite resin. The shear bond strength of each experimental group was measured by MTS and the changes of zirconia core surface according to surface treatments were obtained by SEM observation and measurements of surface roughness. The mean shear bond strength values are $0.55\;{\pm}\;0.11MPa$(Group SC) and $1.16\;{\pm}\;0.46MPa$(Group SRC). The mean Ra values for the surface treatments were follows: $0.39\;{\pm}\;0.13$($100{\beta}_{{\mu}m}$ sandblast) and $0.50\;{\pm}\;0.03$($100{\beta}_{{\mu}m}$ sandblast + $Rocatec^{TM}$ system). In the analysis of EDS, Si element was detected in the Group SC. The shear bond strength between zirconia core and indirect composite resin was improved significantly by using $Rocatec^{TM}$ system.

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스마트폰 어플리케이션을 이용한 뇌졸중 환자의 보행 평가 가능성 (Potential Use of a Smartphone to Evaluate Gait during Walking in Stroke Patients)

  • 안보라;기경일;우영근
    • PNF and Movement
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    • 제16권1호
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    • pp.67-73
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    • 2018
  • Purpose: Smartphones, which are widely used worldwide to detect acceleration and position, have been used in the area of rehabilitation medicine in recent clinical research studies and tests. The aim of the present study was to determine the feasibility of using a smartphone application based on center of movement (COM) displacement to measure gait parameters in stroke patients in the clinical field of rehabilitation medicine. Methods: The study consisted of 30 stroke patients. The COM was measured using a smartphone application, Gait Analysis Pro, during a 6-m walk. Each patient performed three 6-m walking trials, and the smartphone application measured gait duration, gait speed, step length, cadence, and vertical and lateral displacement of the COM. The Kolmogorov-Smirnov test was conducted to determine the normality in gait parameters, and a repeated one-way analysis of variance (ANOVA) was performed to determine the consistency among the three trials. A p value of 0.05 was considered statistically significant in all the tests. Results: In all the measured parameters, the smartphone application showed a normal distribution, as shown by the results of the Kolmogorov-Smirnov test. There were no significant differences among the three repetitive walking trials. Conclusion: These results suggest that the smartphone application can be used for evaluating gait in stroke patients, as well as in healthy adults. However, prior to using the smartphone application in the clinical field, further research involving three-dimensional gait analysis is needed to enhance the confidence level of the findings.

부항자극에 대한 배수혈 어혈평가를 위한 색소침착 변화분석 (Analysis of Hyperpigmentation Change for Extravasated Blood Evaluation by Cupping Stimulation)

  • 김수병;이나라;주예일;이용흠;정병조
    • Korean Journal of Acupuncture
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    • 제28권1호
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    • pp.53-60
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    • 2011
  • Objectives : Cupping therapy has been used as various treatment methods in oriental medicine clinic for a long time. Specially, Cupping stimulation caused skin hyperpigmentation which has been used as diagnosis method for extravasated blood & inner organs functional disease. But it was difficult to quantitatively measure and analyze the interrelation between extravasated blood and skin hyperpigmentation. The aim of this study is to measure the acupoint's RGB and melanin change pattern by stimulating under fixed 80kPa negative pressure and to evaluate the extravasated blood. Methods : To evaluate extravasated blood, 10 acupoints (left/right BL13, BL15, BL18, BL20, BL23) were stimulated by treatment 80kPa negative pressure for 1 minute. And then we measured the acupoints' skin color change patterns using the color meter, followed by RGB analysis and melanin change pattern. Results and Conclusions : We could observe the correlation of the acupoints' skin color condition related with RGB change pattern. All acupoints' color change degree were different. Regardless of acupoints' color degree due to extravasated blood, we observed in common the fact that RGB values decreased after stimulation and steadily increased according to time. We observed that melanin index increased after stimulation and recovered before stimulation-condition after the lapse of time. In other words, we confirmed the correlation between raised color change degree and $L^*a^*$ index change pattern. Therefore we observed the possibility of charting the $L^*a^*$ index following extravasated blood.

Effect of Antioxidant Addition on Milk Beverage Supplemented with Coffee and Shelf-life Prediction

  • Kim, Gur-Yoo;Lee, Jaehak;Lim, Seungtae;Kang, Hyojin;Ahn, Sung-Il;Jhoo, Jin-Woo;Ra, Chang-Six
    • 한국축산식품학회지
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    • 제39권6호
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    • pp.903-917
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    • 2019
  • This study aimed to extend the shelf-life of coffee-containing milk beverage by adding Theobroma cacao (cacao nibs) extract. To prepare the beverage sample containing cacao nibs extract, 0.8% cacao nibs hydrothermal extract was aseptically injected. Qualitative changes in the beverage samples, including antioxidant effect, peroxide value (POV), caffeine content, and sensory parameters were monitored regularly during storage at 10℃, 20℃, and 30℃ for 4 wk. The inclusion of cacao nibs extract produced higher antioxidant activity compared to the control. As the storage temperature increased, the POV of all samples increased. Samples with cacao nibs extract generally displayed lower POV than the control. The caffeine content of all samples tended to decrease during storage, with the decrease accentuated by higher storage temperatures. In the shelf-life prediction using the Arrhenius model, the kinetic regressions of the cacao nibs extract-added sample and control were YPOV=1.2212X-2.1141 (r2=0.9713) and YPOV=1.8075X-2.0189 (r2=0.9883), respectively. Finally, the predicted shelf-life of cacao nibs-added group and control to reach the quality limit (20 meq/kg POV) were approximately 18.11 and 12.18 wk, respectively. The results collectively indicate that the addition of cacao nibs extract extends the shelf-life of the coffee-containing milk beverage and heightened the antioxidant effect.

극소형 MEMS 우주망원경 탑재체 개발 및 탑재

  • 이직;김지은;나고운;남신우;남지우;박일흥;서정은;이혜영;전진아;정수민;정애라;박재형;이창환;박용선;유형준;김민수;김용권;유병욱;이경건;진주영
    • 한국우주과학회:학술대회논문집(한국우주과학회보)
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    • 한국우주과학회 2009년도 한국우주과학회보 제18권2호
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    • pp.47.4-47.4
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    • 2009
  • 초소형전기기계시스템(MEMS: Micro-Electro-Mechanical Systems) 기술로 제작된 마이크로미러 어레이를 장착한 MEMS 우주망원경은 특유의 광시야각 감시, 목표 확인, 확대 및 고속 추적 기능을 가지며 고층대기에서의 초대형 방전현상과 같이 넓은 영역에서 드물게 임의로 일어나는 섬광현상을 관측하기에 최적이다. 러시아 과학위성 Tatiana-2의 주 탑재체로 선정된 극소형 MEMS 우주망원경 MTEL(MEMS Telescope for Extreme Lightning)은 광시야각 감시와 목표 확인을 위한 트리거망원경, 목표 확대와 고속추적을 위한 확대망원경 및 섬광현상의 분광측정을 위한 분광계로 구성되어 있다. 1년간의 개발 및 성능 검증 후 MTEL은 위성탑재를 위한 모든 우주인증 시험을 성공적으로 마쳤다. 현재 MTEL은 Tatiana-2 위성에 탑재되어 있으며, 9월 18일에 우주로 발사되어 1-3년간 800km 궤도를 비행하며 지구 대기에서 발생하는 섬광현상을 관측할 예정이다. 이 발표에서는 MTEL 탑재체의 설계, 제작, 성능 측정 및 calibration 결과를 보고하고, 위성탑재를 위한 진동 및 충격, 열, 진공 및 전자기파 적합성 등의 우주인증 시험 결과 또한 보고한다. 또한 발사 후 과학위성 및 MTEL의 이 발표 때까지의 우주에서의 상황을 보고한다.

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Evaluation of the Oral Acute Toxicity of Black Ginseng in Rats

  • Lee, Mi-Ra;Oh, Chang-Jin;Li, Zheng;Li, Jing-Jie;Wang, Chun-Yan;Wang, Zhen;Gu, Li-Juan;Lee, Sang-Hwa;Lee, Jae-Il;Lim, Beong-Ou;Sung, Chang-Keun
    • Journal of Ginseng Research
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    • 제35권1호
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    • pp.39-44
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    • 2011
  • We studied the acute oral toxicity of black ginseng (BG) produced by heat process in rats. Single acute BG extract doses of 0, 5, 10, and 15 g/kg dissolved in saline were administered by oral gavage and the animals were kept under observation for 14 days. The single administration of BG extract up to 15 g/kg did not produce mortality, behavioral change or abnormal clinical signs in the rats. These results indicated that the oral $LD_{50}$ of the BG extract in the rats is higher than 15 g/kg. Compared to the control group, no treatment-related biologically significant effects of BG extract were noted in the measurements of the body weight or food intake. At the end of the period, the biochemical parameters and hematological parameters were analyzed in the plasma and blood. A histopathological examination of the liver and kidney was also conducted. Only the blood nitrogen urea and potassium levels in the biochemical indices showed significant differences at 10 and 15 g/kg doses of BG extract compared to the control group. These changes were not considered to be due to the toxicity. None of the other clinical chemistry parameters were affected. Therefore, these results indicate that the BG by heat processing is virtually nontoxic.

잠금장치 작동에 따른 미서기 및 LS 창호 시스템의 기밀성 (Effect of Lock Operations on Airtightness of Sliding and LS Window Systems)

  • 박종준;윤유라;김영일;정광섭
    • 설비공학논문집
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    • 제27권9호
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    • pp.449-454
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    • 2015
  • In this study, the effects of lock operations on the infiltration rates for the two window types sliding and lift sliding (LS) are investigated through experiment and simulation. The airtightness levels of the two window types-with locks both on and off-were measured according to the KS F 2292 Test method of airtightness that is used for windows and doors. The air-flow rates of both window types with the locks on for a pressure differential of 10 Pa are $1.98m^3/(m^2h)$ and $1.68m^3/(m^2h)$, respectively; with the locks off, the air-flow rates of the sliding and LS windows are $2.64m^3/(m^2h)$ and $5.83m^3/(m^2h)$, respectively, whereby the air-flow rates are 33% higher for sliding and 247% higher for LS. The air change per hour (ACH) was calculated using the ventilation-simulation software CONTAM. For the sliding window, the ACH changed from 0.45 to 0.57 when the lock was operated from on to off, representing an increase of 27%. For the LS window, the ACH changed from 0.29 to 0.81, showing an increase of 179%.

초고에너지 우주선과 고층대기 극한방전 현상 관측을 위한 TUS(Tracking Ultraviolet Setup) 및 Pinhole Camera 개발 및 진행상황

  • 김민빈;김지은;김예원;나고운;박일흥;서정은;이직;정애라
    • 천문학회보
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    • 제37권2호
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    • pp.209.1-209.1
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    • 2012
  • TUS(Tracking Ultraviolet Setup)는 5x1019 eV 이상의 초고에너지 우주선의 스펙트럼과 그 기원, 그리고 고층대기 극한방전 현상(TLE) 관측을 위한 우주망원경이다. 위성 Lomonosov의 탑재체로 2013년에 발사예정에 있으며 지구로부터 550km 상공에서 지구를 돌며 3년 이상 임무를 수행할 예정이다. TUS는 크게 반사경과 Detector Module 두 부분으로 나뉜다. 7개의 육각형 프레넬 거울을 이용한 $2m^2$ 크기의 반사경과 256개의 PMT(Photo Multiplier Tube)로 구성된 Detector Module을 이용하여 지구 대기에서 초고에너지 우주선에 의해 발생하는 UV fluorescence와 Cherenkov light를 관측한다. TUS Detector Module의 한 부분인 Pinhole Camera는 본 연구단의 기술로 직접 개발한 탑재체로서 TUS 반사경을 통하지 않고 두개의 $8{\times}8$ 어레이 MAPMT (Multi Anode PMT)가 직접 지구를 바라보며 고층대기 극한방전 현상을 관측한다. Pinhole camera는 TUS의 시야각을 포괄하는 넓은 시야각을 가지고 있으며 빠른 트리거 시스템으로 고층대기 극한 방전 현상을 관측하며, 이 방전현상과 TUS가 관측하는 초고에너지 우주선과의 상관 관계를 연구한다. 현재 TUS 및 Pinhole Camera는 러시아에서 조립되어 우주환경 인증 시험 및 인터페이스 테스트가 진행되고 있다. 본 발표에서는 TUS와 Pinhole Camera를 소개하고 현재까지의 진행상황 및 테스트 결과에 대해 보고하고자 한다.

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