• The Journal of Dong Guk Oriental Medicine
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• v.5
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• pp.187-196
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• 1996

Alcohol is a major risk factor for several diseases and especially excessive, long-term alcohol consumption are caues the damage of immunity such as the inhibiton of secretion of lymphokine and proliferation of immune component cell. This study observed that the inhibition of T lymphocytic differentiation and secretion of interleukin 2(IL-2) induced in thymus of ICR mouse by chronic alcohol administration. After 8% alcohol voluntary administered for 120 days, the thymic tissue immunohistochemically stained by following ABC method that used monoclonal antibody including L3T4(CD4), Ly-2(CD8), and IL-2 receptor(CD25R) after embedding with paraffin. The results were as follows. 1. The size of thymic medulla in test group reduced than control group. 2. The number of helper T lymphocyte, cytotoxic T lymphocyte, and IL-2 receptor were decreased in thymic medulla and cortico-medullary junction of test group and the degree of CD4, CD8, and CD25R positive reaction were soften in test group. These results indicated that the secretion of IL-2 in thymus was inhibited by chronic alcohol administration and subsequently prevent to differentiate from thymocytes to T lymphocytes. As this view, cell mediated immunity were reduced by chronic alcohol administration.

• Journal of Pharmacopuncture
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• v.6 no.3
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• pp.39-47
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• 2003

Background & Methods : In order to measure the acute and subacute toxicity of Vermilionum and it's anti-cancer effects, Sarcoma-180 abdominal cancer cells were injected intravenously. The following results were obtained after measuring the survival rate, toxicity of the NK cells, and IL- 2 productivity. Results : 1. It was impossible to measure $LD_{50}$ value in the acute toxicity test and no toxic effects were witnessed in the clinical observation. 2. No significant differences were shown in the weight changes between the experiment groups and the control group in the acute toxicity test. 3. No peculiar toxic effects were shown in the subacute toxicity test and the weight changes were insignificant between the experiment groups and the control group. 4. In measuring the survival rate after inducing abdominal cancer by Sarcoma-180, the experiment groups showed increased of 9.52% compared to the control group. 5. In measuring the activity of NK cells, no significant changes were shown between the experiment groups and the control group. 6. In measuring the productivity of IL-2, significant reduction was shown in the experiment groups compared to the normal group, but no significance was witnessed compared to the control group.

• The Journal of Korean Obstetrics and Gynecology
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• v.26 no.3
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• pp.18-32
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• 2013

Objectives: In this research, the effect of Gyogam-dan (GGD) on depression and immunity were assessed in ovariectomized rats subjected to repetitive stress. GGD is the prescription consisting of Poria cocos and Cyperi Rhizoma. Methods: Ovariectomized rats were repeatedly stressed over a 2-week period. After GGD (100 or 400 mg/kg) were orally administered, Elevated Plus Maze (EPM) and forced swimming test (FST) were performed to evaluate depressive and anxiety response. As well, the change of corticosterone (CORT) and the change of interleukin-$1{\beta}$ (IL-$1{\beta}$) and interleukin-4 (IL-4) in blood serum and in brain were mesured. Results: 1. In the EPM, there were no statistically significant differences among the groups. 2. In the FST, immobility time significantly decreased in rats of each experiment group compared with the control group (p<0.01). 3. Serum CORT level were decreased in 400 mg GGD group (p<0.05). 4. On IL-$1{\beta}$ and IL-4 measurement in the serum and brain, there were not significant increase or decrease compared with the control group. Conclusions: These results suggest that GGD is effective to reduce depression-behavior in ovariectomized rats. However, GGD do not has significant efficacy to reduce anxiety-behavior in EPM test. Measurement of serum CORT level reveals significant decrease and it shows anti-depressant like effect. Results on immunity are not significant.

• Journal of Astronomy and Space Sciences
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• v.16 no.2
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• pp.191-198
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• 1999

Results of RF compatibility test between KOMPSAT(Korea Multi-Purpose SATellite) and TTC(Tracking, Telemetry, and Command) station are described. S/C(Spacecreft) RF Test, telemetry test, command test, ranging test, and tracking receiver test were performed with respect to pass/fail criteria. To provide physical RF interface between KOMPSAT and TTC equipment, direct low cable and antenna-to-antenna interface were implemented. Through RF compatibility test, it was fully demonstrated that KOMPSAT and TTC equipment are functionally workable.

• Proceedings of the Korean Geotechical Society Conference
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• 2009.03a
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• pp.518-525
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• 2009

The bi-directional high pressure pile load test(BDH PLT) which is a kind of pile load tests was conducted to find out a reasonable design procedure of large-diameter drilled shafts of large-size building structures. The behaviors of bearing capacity and settlement of the large-diameter drilled shafts were analyzed and the results obtained from BDH PLT were also compared with those obtained from the equations suggested in the specification. In case of the reasonable design procedure adopted, the construction cost could be saved at least 15 ~ 28%. It could be concluded that BDH PLT should be needed for the foundation construction cost reduction of the high-rise building structures.

• Proceedings of the KIEE Conference
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• 1996.11a
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• pp.109-111
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• 1996

This paper describes real time dynamic tests on the digital distance relay using new digital test system including RTDS(Real Time Digital Simulator) in KEPRI. The RTDS is developed by the Manitoba HVDC Reserch Centre and consists of specialized hardware and software which allows transients simulation of electrical power systems in real time. From high impedance fault test, it is known that the characteritics of distance reach is influenced by load flow. A detailed discussion of relay test using the RTDS simulator, high impedance faults and test results are included in the paper.

• Journal of Ginseng Research
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• v.20 no.1
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• pp.15-22
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• 1996

In order to investigate the Immunomodulatory effects of ginseng, we have studied the effects of ginseng saponin on the proliferation and cytosine gene expression of human pheripheral blood mononuclear cell (PBMC). In the PBMC proliferation assay, total saponin exhibited proliferation inhibition on the PBMC or phytohemagglutinin(PHA)-stimulated PBMC in a dose-dependent fashion. Immunomodulatory effects of ginseng were further investigated using the cytokine gene expression as the indicators. In the reverse transcription-polymerase chain reaction (RT-PCR) test, interleukin (IL)-1, IL-2, IL-3, IL-4, IL-6, IL-13, granulocyte macrophage-colony stimulating factor, tumor necrosis factor (TNF), migration inhibitory factor and transforming growth factor genes were expressed in the PHA-stimulated PBMC 48 hrs after cell culture. Among expressed cytokines, total saponin could increase the expression of IL-1 and TNF of PBMC without stimulation of PHA. All of ginsenosides, $Rb_1$, $Rb_2$, $Rg_1$, Rc, Re, incresed TNF gene expression. Especially, Rb2 (20 g/ml) showed most prominent effect on TNF gene expression and it also slightly increased IL-1 gene expression of PBMC.

• Journal of Fisheries and Marine Sciences Education
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• v.21 no.1
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• pp.59-67
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• 2009

It is necessary for navigator to understand sufficiently maneuverabilities based on experiences and the data which were gotten from several tests of the ship when he maneuver his vessel. By the way most navigators used to rely on his experiences or feelings only maneuvering ship. But when he encounters situations he did not experience before he may be in difficulties. So navigator must get both experiences and data based on experimental results. In this paper author performs several tests such as turning test, Zig-zag test and spiral test to provide informations of maneuverabilities for navigators. The obtained results are as follows: There occurs almost no difference in size of the turning circle by the changes of ship's speeds. The scale of the turning circle was decreased exponentially when the rudder angle was increased. The maneuverabilities is better turning to starboard side than to port side. Maneuverabilities are more effective when the rudder is used to small angle than to large angle. As a result of spiral test course stability was comparatively seemed to be good.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.4
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• pp.33-41
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• 2019

Purpose : The muscle strength of iliopsoas (IL) was measured commonly in sitting position with hip and knee flexed 90°. However, there is no study to determine the muscle strength of IL in various test positions. Therefore, the purpose of this study was to compare the muscle strength of IL and muscle activity of rectus femoris (RF) according to test position and knee flexion angle. Methods : Twenty healthy subjects were participated for this study. The muscle strength of IL and muscle activity of RF were measured by hand-held dynamometer and surface electromyography during maximum voluntary isometric contraction (MVIC) of IL, respectively. The muscle strength of IL and muscle activity of RF was measured in 4 conditions as follows; 1) knee flexion angles 90 ° in supine, 2) 130 ° in supine position, 3) 90 ° in sitting, 4) 130 ° in sitting. Each condition were performed randomly by three repetitions. Results : The muscle strength of the IL was the main effect on the test position and knee flexion angle (p<.05), and the muscle activity of RF was the main effect only on the knee flexion angle (p<.05). There was also no interaction between the factors (p>.05). In supine position, the muscle strength of IL in knee flexion 130 ° was significantly less than that in knee flexion 90 ° (p<.0125). In knee flexion 90 °, the muscle strength of IL in supine position was significantly greater than that in sitting position (p<.0125). The muscle activity of RF in knee flexion 130 ° was significantly less than that in knee flexion 90 ° in supine and sitting positions (p<.0125). Conclusion : When the muscle strength of IL was measured in clinic and sports fields, the supine position with knee flexion 130 ° was recommended to prevent the muscle activation of RF and to maintain the trunk stability.

• 대한핵의학회:학술대회논문집
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• 1972.11a
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• pp.72.1-72.1
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• 1972