• Proceedings of the Korea Information Processing Society Conference
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• 2001.04b
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• pp.929-932
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• 2001

인터넷 정보 가전(IIA; Internet Information Appliance)내에 내장형 DBMS 의 개발은 다양한 이종 네트워크의 통신을 지원하기 위한 미들웨어(Middleware, i.e. OSGi)의 지원이라는 문제를 해결해야만 하기 때문에, 이들 미들웨어와의 인터페이스라는 문제가 기존의 데이터베이스 엔진을 개발하는 문제와 가장 큰 차이점이라 할 수 있다. 이외에는 일반적인 메모리 상주 데이터베이스 엔진 (nain memory DBMS)을 개발하는 것과는 별다른 큰 차이점이 아직까지는 연구되지 않고 있다. 하지만, 가정이라는 지역적인 특성을 고려한 데이터 서비스를 먼저 염두에 두어야 하며, 이에 따라 다양한 응용 소프트웨어를 쉽게 개발할 수 있는 방향으로 제작이 되어야 한다는 점을 늘 고려해야 한다. 본 논문에서는 이와 같은 인터넷 정보가전용 내장형 DBMS 개발 사업에 관하여 현재까지 본 과제에서 논의되고 있는 요구사항을 분석한 결과를 정리하고, 이에 관한 토론을 하고자 한다.

• Korean Journal of Pharmacognosy
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• v.33 no.1 s.128
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• pp.49-52
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• 2002

Amentoflavone, naturally occurring biflavonoid, isolated from the leaves of Ginko biloba, selectively inhibited human seceretory phospholipase $A_2$. This compound potently and irreversibly inhibited human group IIA in a dose dependent manner with an $IC_50$ about $3\;{\mu}M$. Amentoflavone inhibited phospholipase $A_2$ by a noncompetitive manner with the apparent Ki value of $1{\times}10^{-5}M$. In addition, the inhibitory activity of amentoflavone is rather specific against group IIA phospholipase $A_2$ than group IB phospholipase $A_2$. Furthermore, this compound strong inhibit histamine release from $A_{23187}$ treated rat peritoneal mast cells. These results indicate naturally occurring biflavonoid represents a novel anti-inflammatory agent.

• Reproductive and Developmental Biology
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• v.29 no.4
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• pp.229-234
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• 2005

Methods for activation of reconstructed oocytes were examined for the production of nuclear transfer (NT) rat embryos using fetal neural stem cells as donor. Neural stem cells were isolated from Day 14.5 rat fetuses, and the oocytes for recipient cytoplasm were recovered from 4-week old Sprague Dawley rats. After enucleation and nuclear injection, the reconstructed oocytes were immediately exposed to activation medium consisting of 10 mM $SrCl_2$ for 4 h (immediate activation after injection; IAI), or cultured in vitro for $2\~3$ h before activation treatment (injection before activation; IBA). Pre-activated oocytes were also used for NT to test reprogramming potential of artificially activated oocytes. The oocytes were grouped as IIA (immediate injection after activation) and ABI (activation $2\~3$ h before injection). Following NT, the oocytes were cultured in vitro. Development of the NT embryos was monitored at 44 and 119 h after activation. The embryos in groups IAI, mA, and IIA were cleaved to the 2-cell stage at the rates of $36.6\%\;(15/41),\;39.5\%\;(17/43)\;and\;46.3\%$ (25/54), respectively. However, in the ABI group, only one embryo ($1.8\%$, 1/55) was cleaved after activation. After in vitro culture, two NT embryos from IAI group had developed to the morula stage $(4.9\%\cdot2/41)$. However, no morula or blastocyst was obtained in the other groups. These results suggest that immediate activation after injection (IAI) method may be used for the production of rat somatic cell NT embryos.

• Archives of Pharmacal Research
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• v.27 no.12
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• pp.1233-1237
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• 2004

The effects of four tanshinones isolated from Tanshen (the root of Salvia miltiorrhiza Bunge, Labiatae) were tested for their inhibition of nitric oxide production in macrophage cells, and the underlying molecular mechanisms studied. Of the four tanshinones used, 15, 16-dihydrotanshinone- I, tanshinone-IIA and cryptotanshinone, but not tanshinone I, demonstrated significant inhibition of the LPS-induced nitric oxide production in RAW 264.7 cells, with calculated $IC_{50}$ values of 5, 8, and 1.5 ${\mu}M$ , respectively. Tanshinones exerted inhibitory activities on the LPS-induced nitric oxide production only when applied concurrently with LPS, and tanshinone- IIA and cryptotanshinone were found to inhibit LPS-induced NF-$_KB$ mobilization and extracellular- regulated kinase (ERK) activation, respectively. These results suggest that tanshinones inhibit LPS-induced nitric oxide generation by interfering with the initial stage of LPS-induced expression of certain genes. NF-$_KB$ and ERK could be the molecular targets for tanshinones for the inhibition of LPS-induced nitric oxide production in macrophage cells.

• The Korean Journal of Pesticide Science
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• v.3 no.2
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• pp.86-89
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• 1999

A series of methanesulfonamide (I a- I g) and phenylhydrazone (IIa-IIh) derivatives were synthesized and their fungicidal activity in vitro against gray mold (BC: Botrytis cinerea), phytophthora blight (PC: Phytophthora capsici) and sheath blight (RS: Rhizoctonia solani) were measured by agar dilution method. The (II) deriviatives showed higher activity than ( I ) derivitives. And the relative orders of the fungicidal activity are BC=PC>RS, Among these compounds, 3-chlorophenyl substituent, IIg showed the most highest activity ($pI_{50}=3.96$) against PC. From the parameter focusing technique, major factors on the activity were ovality, polar and logP constant and so on.

• Proceedings of the KIEE Conference
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• 1998.07c
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• pp.1121-1124
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• 1998

Inchon International Airport(IIA) is constructed for Northeast Asia Gate as is important for IIA to become a 21 century's leader in the world, as is planned for open at december 2000 as a important economic link for unified korea. Airport Power Information System(APIS) is designed through investigation of advanced domestic and international example. In addition to power facility operation it is designed for using an information infrastructure of whole airport. APIS is newly designed for uninterupted power supply, effective power management, information infrastructure's construction. making a profit by positively introduction of new technology for collection and conservation of power related data, correlation with airport infra systems, data interrelative arrangement about related systems like outdoor lighting system and automatic measuring record, CCTV systems for remote power facility monitoring, and promotion of management ability in the emergency status.

• Archives of Pharmacal Research
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• v.28 no.4
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• pp.438-442
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• 2005

A series of 3-[1-(4-(2-methylpropyl) phenyl) ethyl]-1,2,4-triazole-5-thione (I) and its bicyclic condensed derivatives 6-benzylidenethiazolo[3,2-b]-1, 2,4-triazole-5(6H)-ones (IIa-IIf) were investigated for the prevention of ethanol-induced oxidative stress in liver and brain of mice. Administration of ethanol (0.1 mL/mice, p.o.) resulted in a drop of total thiol groups (T-SH) and non-protein thiol groups (NP-SH), and an increase in thiobarbituric acid reactive substances (TBARS) in both liver and brain tissue of mice (p<0.001). Among the compounds investigated (at a dose of 200 mg/kg, p.o.), I and IId ameliorated the peroxidative injury in these tissues effectively. Compounds IIa, IIc and IIe improved the peroxidative tissue injury only in brain. These findings suggest that certain condensed thiazolo-triazole compounds may contribute to the control of ethanol-induced oxidative stress in an organ selective manner.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.7 no.6
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• pp.1034-1039
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• 2006

The purpose of this paper is to evaluate the structural integrity of the Class 1500 Bellows Seal 3 inch globe valve classified as seismic category IIA. The finite element analysis program, ANSYS, Version 10.0, is used to perform both a modal frequency analysis and an equivalent static stress analysis of the subject valve modeling. The modal frequency analysis results show the fundamental natural frequency is greater than 33 Hz. Therefore the equivalent static stress analysis is performed using the seismic acceleration values. The stresses resulted from various loadings and their combinations are evaluated based on the structural acceptance criteria of the ASME Code. The stresses in the glove valve due to the seismic loadings are within the allowable limits. It is concluded that the globe valve structure is maintaining the structural integrity fur the seismic loading conditions.

• Korean Journal of Clinical Laboratory Science
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• v.37 no.3
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• pp.149-154
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• 2005

Fifty-one extended-spectrum-${\beta}$-lactamase(ESBL) producing Klebsiella pneumoniae strains were isolated from national university hospitals. All K. pneumoniae strains showed resistance to broad-spectrum antibiotic and most of them presented resistance to amikacin, gentamicin and ciprofloxacin. The results of amplified polymorphic DNA (RAPD) pattern for randomly isolated fifty-one strains were as follows; both twenty-one strains from Chungnam National University hospital and ten strains from Chungbuk National University hospital showed RAPD type Ia and Ib. However, twenty strains isolated from Gyeongsang National University hospital belonged to RAPD type IIa and IIb. All isolates were divided into four molecular types and showed high level of genetic diversity. These results suggested that RAPD analysis provided a rapid and simple method for analysing genotypes of ESBL.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.92-92
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• 2016

최근 도시유역의 홍수들이 빈번히 발생하고 있다. 2010년 2011년에는 서울 지역에서 연이은 도시 홍수피해가 발생하였고, 2015년 미국 South Carolina, 프랑스, 중국 지역에서 많은 홍수 피해가 발생 했다. 도시유역에서 홍수피해가 증가하고 있는 주요 원인은 기후변화로 인한 극한 홍수의 증가, 도시화로 인한 불투수면적의 증가, 배수관망의 통수능 부족 등이라 할 수 있다. 본 연구는 앞서 제시한 세가지 원인들 중 불투수면적의 증가 및 배수관망의 통수능 부족 부분에 대하여 기존 연구와는 다른 시각으로 접근하여 도시유역의 홍수유출 저감방안에 대한 연구를 수행하였다. 본 연구에서는 서울의 신월 배수분구를 대상으로 첫 번째 불투수지역들 중 강우발생시 홍수유출에 직접적인 영향 미치는DCIA(Directly Connected Impervious Area)지역과 IIA(Isolated Impervious Area)를 분리하여 홍수유출 특성을 분석하였고, 두 번째는 배수 관망의 통수능 부족 문제를 해결하기 위해서 관망의 통수능을 증가시키는 방법이 아닌 홍수 유출을 저감할 수 있는 적정 배수관망 레이아웃을 산정한 후 이를 SWMM 모형에 적용하여 기존 배수관망 시스템과 적정 배수관망 시스템의 홍수저감량을 비교하였다. 마지막으로는 첫번째 방법과 두 번째 방법을 동시에 적용하였을 때의 홍수저감량을 검토하여 최적의 도시유역의 홍수유출 저감방법을 제시하고자 한다.