• Transactions of the Korean Society of Mechanical Engineers A
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• 제20권4호
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• pp.1347-1355
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• 1996

The purpose of this paper is to evaluate the delamination and fracture integrity of the IC plastic package under hygrothermal loading by stress analysis and fracture mechanics approaches. The plastic SOJ package with a dimpled diepad under the reflow slodering process of IR heating type is considered. On the package without a crack, the stress variation according to the change of the design variables such as the material and shape of the package is calculated and the possibility of delamination is considered. For the model fully delaminated between the chip and diepad, J-integrals are calculated for the various design variables and the fracture integrity is discussed. From the results, optimal design values of variables to prevent the delamination and fracture of IC package are obtained. In this study, FDM program to obtain the vapor pressure from the content of moisture absorbed into the package is developed.

• Journal of the Korean Society for Precision Engineering
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• 제6권3호
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• pp.90-99
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• 1989

In this study, J-integral values obtained by various methods, i.e, R-Curve, Unloading Compliance, Strectched Zone Width [SZW], and Acoustic Emission [AE] methods are investigated. Elasto-plastic fracture toughness [$J_IC$] estimations by R-curve method are overestimated than those by SZW method, and those by unloading compliance method is around middle value of them. And the difference between them is little. The $J_IC$ value by AE method was almost agreed with that by SZW, and then proved to be useful. Crack propagation mechanism on fractography is a stable ductile fracture. For the identification of ductile fracture, both fractography analysis and AE method were applied to estimate the characteristics more precisely.

• Transactions of the Korean Society of Mechanical Engineers
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• 제10권5호
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• pp.680-688
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• 1986

In order to obtain the optimal estimation method of fracture toughness of dual phase steel in which martensitic phase encapsulated islands of ferritic phase, the stretched zone (SZ) method and the R-curve method of the JSME S 001 was discussed. The results obtained are as follows. (1) The $J_{IC}$ values estimated by the SZ method are overestimated as compared with those by the R-curve method. (2) The $J_{IC}$ by the R-curve method decreases with the increase of the ferrite grain size and the martensite hardness. (3) The overestimation of $J_{IC}$ by the SZ method is due to the continuous plastic blunting of ferrite after the formation of stable crack which affects the critical stretched zone width.

• Journal of the Korea Concrete Institute
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• 제13권4호
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• pp.371-378
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• 2001

Recently, the parameters, models, and experimentations, which evaluate the fracture properties of concrete, have been proposed by many researchers, and their developments allow us to analyze the non-linear and quasi-brittle fracture mechanisms. In this paper, a brief treatment of the fracture parameters was presented and the experiments of 3-point bending tests were conducted to compare J-integral($J_{Ic}$ /) with other parameters($K_{Ic}$ , $G_{v}$ , and $G_{F}$ ). The change of parameter values according to the width and notch length of concrete beam specimens was also considered. The load-displacement curves are used to experimentally measure concrete fracture toughness. From the results of experiment, it is noted that the value of $GF$ and tic decreases as the notch depth increases and $G_{F}$ is less sensitive than $J_{Ic}$ . Therefore, the former is more appropriate to use as the concrete fracture toughness parameter. The values of $v_{v}$ and $J_{Ic}$ increase when the width of concrete specimens increase from 75 mm to 150 mm. Therefore, the effects of specimen width need to be considered in determining the concrete fracture toughness.

• Journal of Applied Biological Chemistry
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• 제50권4호
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• pp.215-220
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• 2007

One of the important functions of skin is protection from harmful environments. Many studies have explored how to prevent skin from wrinkling and the occurrence of pigmentation changes. Skin wrinkling and pigmentation changes could be caused by unusual disruption of connective tissue, the formation of free radicals and ultraviolet radiation. In this study, extracts obtained from 254 different kinds of Jeju medicinal plants were screened for inhibitory effects on tyrosinase and elastase, and for free radical scavenging effects. Four herbs, Phormium tenax, Morus bombycis, Morus alba, and Cudrania tricuspidata, were potent inhibitors of tyrosinase ($IC_{50}$ values 4.62, 5.46, 8.17, and 64.17 ${\mu}g$/mL, respectively). Aleurites fordii [$IC_{50}$: 5.29 ${\mu}g$/mL, 1,1-diphenyl-2-picrylhydrazyl (DPPH)], Distylium racemosum ($IC_{50}$: 6.14 ${\mu}g$/mL), Acer palmatum ($IC_{50}$: 5.44 ${\mu}g$/mL), and Spiraea salicifolia ($IC_{50}$: 5.25 ${\mu}g$/mL) showed good antioxidative effects. Furthermore, Distylium racemosum ($IC_{50}$: 7.51 ${\mu}g$/mL), Diospyros kaki ($IC_{50}$: 15.1 ${\mu}g$/mL), Cornus macrophylla ($IC_{50}:$ 16.59 ${\mu}g$/mL), and Psidium guajava ($IC_{50}$: 40.25 ${\mu}g$/mL) exhibited potent inhibitory effects on elastase. These results suggest that medicinal plants possessing several biological activities may be potent inhibitors of the processes involved in pigmentation increases and aging. Further investigations will focus on in vivo assays and on the chemical identification of the major active components responsible for whitening and anti-aging activity in the screened efficacious extracts.

• Journal of Radiation Protection and Research
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• 제25권4호
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• pp.183-190
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• 2000

Medicinal plants with synergistic effects on growth inhibition of canter cells under oxidative stress were screened in this study. Methanol extracts from 51 natural medicinal plants which were reported to have anticancer effort on hepatoma stomach cancer or colon cancers which are frequently found in Korean, were prepared and screened for their synergistic activity on growth inhibition of cancer cells under chemically-induced oxidative stress by using MTT assay. Twenty seven samples showed synergistic activity on the growth inhibition in various extent under chemically-induced oxidative stress. Among those samples, eleven samples such as Melia azedarach, Agastache rugosa, Catalpa ovata, Prunus persica, Sinomenium acutum Pulsatilla koreana, Oldenlandia diffusa, Anthriscus sylvestris, Schizandra chinensis, Gieditsia sinensis, Cridium officinale, showed decrease in $IC_{50}$ values more than 50%, other 16 samples showed decrease in $IC_{50}$ values between 50-25%, compared with the value acquired when medicinal plant sample was used alone. Among those 11 samples, extract of Catalpa ovata showed the highest activity. $IC_{50}$ values were decrease to 61% and 28% when carcinoma cells were treated with Catalpa ovata extract in combination of 75 and 100 uM of hydrogen peroxide, respectively.

• Natural Product Sciences
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• 제11권3호
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• pp.150-154
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• 2005

The radical scavenging effect of the MeOH extract of Fraxini Cortex on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical was examined. The $CH_2Cl_2$-and n-BuOH-soluble fractions of MeOH extract showed the promising DPPH radical scavenging effects, and further purified by silica gel, Sephadex LH-20 column chromatography, and reversed-phase C-18 MPLC to yield five coumarins, esculetin (1), fraxidin (2), fraxetin (3), fraxidin $8-O-{\beta}-D-glucopyranoside$ (fraxin methyl ether) (5), esculin (6), and a secoiridoid oleuropein (4), and a coumarin-secoiridoid escuside (7). Compounds 1, 3, and 4 showed potent DPPH radical scavenging effects, exhibiting $IC_{50}$ values of 14.68, 9.64, and $22.03\;{\mu}M$, respectively. Compounds 6 and 7 also showed moderate effects with $IC_{50}$ values of 147.79 and $72.73\;{\mu}M$, respectively. L-Ascorbic acid was used as a positive control and exhibited the $IC_{50}$ value of $50.31\;{\mu}M$.

• Natural Product Sciences
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• 제21권1호
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• pp.1-5
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• 2015

Activity-guided separation of the methylene chloride-soluble fraction of the leaves of Zanthoxylum schinifolium, resulted in the isolation of four coumarinoids (1 - 4), two triterpenoids (5, 6) and three fatty acid derivatives (7 - 9) as active principles. Their chemical structures were identified as collinin (1), 8-methoxyanisocoumarin (2), 7-(6'R-hydroxy-3',7'-dimethylocta-2',7'-dienyloxy)-coumarin (3), (E)-4-methly-6-(coumarin-7'-yloxy) hex-4-enal (4), lupeol (5), epi-lupeol (6), phytol (7), hexadec-3-enoic acid (8) and palmitic acid (9), on the basis of spectroscopic (1D, 2D and MS) data analyses and comparing with the data published in the literatures. Compounds 1 and 7 showed potent cytotoxicity against Jurkat T cells with $IC_{50}$ values of 45.58 and $47.51{\mu}M$, respectively. The others showed moderate activity with $IC_{50}$ values ranging around 80.58 to $85.83{\mu}M$, while the positive control, auraptene, possessed an $IC_{50}$ value of $55.36{\mu}M$.

• Transactions of the Korean Society of Mechanical Engineers
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• 제11권5호
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• pp.717-724
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• 1987

Mechanical properties tests and fracture toughness tests of turbine rotors were performed in the wide range of temperatures, -150.deg.C-+150.deg.C, and fracture toughness values from above tests were compared with the estimated values from mechanical properties at lower and upper shelf temperatures and FATT. The relations between mechanical properties and $K_{IC}$ properties proposed by Rolfe and Begley were reviewed and confirmed through these experimental results. On the fracture surfaces of some specimens which were satisfied with the Ikeda's $K_{IC}$ criterion micro dimple zone was detected at the rear of fatigue crack zone and it was confirmed that these specimens were not satisfied with the thickness requirement of ASTM E 399.E 399.

• Transactions of the Korean Society of Mechanical Engineers A
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• 제23권11호
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• pp.1886-1895
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• 1999

The delamination behavior of multidirectional carbon-fiber/epoxy composite laminates under 10NA intermediate and high rates of test, up to rate of about 11.4m s has been investigated using the double cantilever beam specimens. The mode I loading under rates above l.0m/s showed considerable dynamic effects on the load-time curves and thus higher values of the average crack velocity than that expected from a simple proportional relationship with the test rate. The modified beam analysis utilizing only the opening displacement and crack length exhibited an effective means for evaluating the dynamic fracture energy $G_{IC}$. Based on the assumption of constant flexural modulus, values of $G_{IC}$ at the crack initiation and arrest were decreased with an increase of the test rate up to 5.7m/s, but the maximum $G_{IC}$ was increased at 11.4m/s.