• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송∙미디어공학회 2017년도 추계학술대회
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• pp.116-117
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• 2017

최근 국내에서 IP 를 기반으로 방송 미디어 콘텐츠를 전송하는 UHD 기반 지상파 방송 서비스가 시작되고, 새로운 방송 환경의 조성으로 기존에는 적용이 어렵던 방송망과 브로드밴드 망을 동시 사용하는 하이브리드 방송 서비스가 등장하였다. 지상파 UHDTV 송수신정합의 서비스 시그널링 파트에서 제공되는 서비스 간 연결 정보를 이용하여 IBB 표준에 따라 TV 로 시청하던 방송 서비스를 개인용 스마트기기와 연계하여 브로드밴드 망을 통해 제공받을 수 있는 새로운 유형의 콘텐츠 소비가 가능해졌다. 이에 본 논문에서는 지상파 UHD 서비스와 IBB 서비스, 연계할 수 있는 개인용 스마트기기 등 여러 요소를 고려한 지상파 UHD 하이브리드 방송 시나리오를 가정하고 이 때 필요한 IBB 서비스 모델을 제안하고 분석한다.

• Journal of Microbiology and Biotechnology
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• 제25권4호
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• pp.459-463
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• 2015

This study evaluated the microbial conversion of coconut oil waste, a major agro-residue in tropical countries, into single cell oil (SCO) feedstock for biodiesel production. Copra cake was used as a low-cost renewable substrate without any prior chemical or enzymatic pretreatment for submerged growth of an oleaginous tropical mangrove fungus, Aspergillus terreus IBB M1. The SCO extracted from fermented biomass was converted into fatty acid methyl esters (FAMEs) by transesterification and evaluated on the basis of fatty acid profiles and key fuel properties for biodiesel. The fungus produced a biomass (8.2 g/l) yielding 257 mg/g copra cake SCO with ~98% FAMEs. The FAMEs were mainly composed of saturated methyl esters (61.2%) of medium-chain fatty acids (C12-C18) with methyl oleate (C18:1; 16.57%) and methyl linoleate (C18:2; 19.97%) making up the unsaturated content. A higher content of both saturated FAMEs and methyl oleate along with the absence of polyunsaturated FAMEs with ≥4 double bonds is expected to impart good fuel quality. This was evident from the predicted and experimentally determined key fuel properties of FAMEs (density, kinematic viscosity, iodine value, acid number, cetane number), which were in accordance with the international (ASTM D6751, EN 14214) and national (IS 15607) biodiesel standards, suggesting their suitability as a biodiesel fuel. The low cost, renewable nature, and easy availability of copra cake, its conversion into SCO without any thermochemical pretreatment, and pelleted fungal growth facilitating easier downstream processing by simple filtration make this process cost effective and environmentally favorable.

• Structural Engineering and Mechanics
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• 제68권6호
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• pp.735-745
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• 2018

The Big Bang-Big Crunch (BB-BC) algorithm is an effective global optimization technique of swarm intelligence with drawbacks of being easily trapped in local optimal results and of converging slowly. To overcome these shortages, an improved BB-BC algorithm (IBB-BC) is proposed in this paper with taking some measures, such as altering the reduced form of exploding radius and generating multiple mass centers. The accuracy and efficiency of IBB-BC is examined by different types of benchmark test functions. The IBB-BC is utilized for damage detection of a simply supported beam and the European Space Agency structure with an objective function established by structural frequency and modal data. Two damage scenarios are considered: damage only existed in stiffness and damage existed in both stiffness and mass. IBB-BC is also validated by an existing experimental study. Results demonstrated that IBB-BC is not trapped into local optimal results and is able to detect structural damages precisely even under measurement noise.

• 방송공학회논문지
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• 제22권1호
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• pp.95-106
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• 2017

디지털 방송 통신 기술의 발전에 따라 고화질 방송 서비스와 함께 컴패니언 스크린 서비스에 대한 관심이 높아지고 있다. 개인 모바일 디바이스 사용이 확산됨에 따라 주 스크린에서 양질의 방송을 제공 하는 것 뿐 아니라 세컨드 스크린에서 부가적인 가치를 창출하는 것도 중요하다. 본 논문에서는 사용자의 컨텍스트에 의거하여 적응적인 컴패니언 서비스를 만드는 플랫폼과 관련 저작 도구를 제안한다. 이를 위해 사용자의 상황에 기반하여 원격으로 리소스를 모으고 조합하여 적응적인 컴패니언 스크린 서비스를 공급하는 플랫폼을 설계하였고 실제 서비스 환경에 맞게 구현하였다. 제안하는 플랫폼은 사용자의 다양한 컨텍스트와 사업자의 요구를 고려하여 양질의 컨텐츠를 실시간 구성하고 사용자에게 제공할 수 있으며 플랫폼 기반 저작 도구는 숙련되지 않은 디자이너와 서비스 기획자도 적응적 컴패니언 스크린 서비스를 쉽고 빠르게 만들 수 있도록 한다. 설계한 플랫폼을 이용하여 인터랙티브 서비스 제공이 가능한 한국 UHD IBB 표준을 준수하는 컴패니언 스크린 서비스 컨텐츠를 만들고 시뮬레이션 하였다.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송∙미디어공학회 2018년도 하계학술대회
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• pp.305-308
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• 2018

최근 국내 지상파 UHD 방송이 시작됨에 따라 시청 중에 방송망과 브로드밴드 망을 통해 IBB 실시간 부가 서비스를 제공 받을 수 있게 되었다. 이에 따라 사업자는 IBB 서비스 표준 중 컴패니언 스크린 서비스 표준에 따라 지상파 UHD 방송 시청자들이 방송 수신기의 컴패니언 디바이스를 사용하여 연관 콘텐츠를 수신할 수 있는 기능을 제공해야 한다. 이에 본 논문에서는 IBB 부가서비스 중 생방송 이어보기 서비스를 컴패니언 디바이스를 통해 제공할 수 있는 시나리오 및 모델을 제시한다. 본 논문의 서비스 모델은 ATSC 3.0 과 HbbTV 2.0 표준의 방송 환경 시스템에서 동작함을 상정한다. 오픈소스 소프트웨어를 사용하여 해당 시스템의 설계 및 구현하여 서비스 동작을 보인다.

• Journal of Microbiology and Biotechnology
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• 제23권9호
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• pp.1308-1321
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• 2013

The emergence of microcarrier technology has brought a renewed interest in anchorage-dependent cell culture for high-yield processes. Well-known in vaccine production, microcarrier culture also has potential for application in other fields. In this work, two types of microcarriers were evaluated for small-scale monoclonal antibody (mAb) production by CHO-K1 cells. Cultures (5 ml) of microporous Cytodex 3 and macroporous CultiSpher-S carriers were performed in vented conical tubes and subsequently scaled-up (20 ml) to shake-flasks, testing combinations of different culture conditions (cell concentration, microcarrier concentration, rocking methodology, rocking speed, and initial culture volume). Culture performance was evaluated by considering the mAb production and cell growth at the phases of initial adhesion and proliferation. The best culture performances were obtained with Cytodex 3, regarding cell proliferation (average $1.85{\pm}0.11{\times}10^6$ cells/ml against $0.60{\pm}0.08{\times}10^6$ cells/ml for CultiSpher-S), mAb production ($2.04{\pm}0.41{\mu}g/ml$ against $0.99{\pm}0.35{\mu}g/ml$ for CultiSpher-S), and culture longevity (30 days against 10-15 days for CultiSpher-S), probably due to the collagen-coated dextran matrix that potentiates adhesion and prevents detachment. The culture conditions of greater influence were rocking mechanism (Cytodex 3, pulse followed by continuous) and initial cell concentration (CultiSpher-S, $4{\times}10^5$ cells/ml). Microcarriers proved to be a viable and favorable alternative to standard adherent and suspended cultures for mAb production by CHO-K1 cells, with simple operation, easy scale-up, and significantly higher levels of mAb production. However, variations of microcarrier culture performance in different vessels reiterate the need for optimization at each step of the scale-up process.

• TTA 저널
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• 통권167호
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• pp.63-68
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• 2016

• 셀메드
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• 제2권4호
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• pp.31.1-31.7
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• 2012

Curcuma longa belongs to the family Zingiberaceae and can be found in the tropical and subtropical regions of the world. It is widely used in Asiatic countries, especially India and South East Asia where it is cultivated commercially as a condiment. Its rhizomes exhibit anti-inflammatory, anti-human immunodeficiency virus, anti-bacterial, antioxidant effects, nematocidal activities, antiproliferative and antiangiogenic activities and are of pharmaceutical importance. Another relevant medicinal property exhibited by it is antidiabetic property which is reviewed here. Studies on the efficacy of crude C.longa extracts against type 2 diabetes in murine models reveal that it demonstrates a hypoglycemic effect by lowering the blood glucose levels under in vivo conditions. Clinical studies have revealed the safety of curucmin (major principle component exhibiting pharmaceutical properties from C.longa) on humans but with very low bioavailability. In view of its effective hypoglycemic effect and its low bioavailability, further studies are needed for the characterization of the bioactive principles and formulating the development of C.longa extracts as a novel anti-diabetic therapeutic agent.

• Bulletin of the Korean Chemical Society
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• 제32권spc8호
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• pp.2906-2910
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• 2011

A fluorescent nucleoside analogue, $^AC$, featuring two non-complementary nucleobases linked through an ethynyl group, was synthesized. The extended ${\pi}$-conjugation imparts $^AC$ with red-shifted absorbance (relative to adenine and cytosine) and pale-blue fluorescence. It spontaneously forms nanoparticles, which exhibit considerably enhanced fluorescence, without the help of any additional stabilizing agent. The DMSO/water ratio was an important factor influencing the construction of the NPs. X-ray crystallography confirmed the structure of $^AC$; dynamic light scattering and scanning electron microscopy confirmed the existence of the nanoparticles.

• 식물분류학회지
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• 제46권4호
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• pp.337-347
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• 2016

Based on genetic studies and palaeoecological surveys, the main Korean mountain range, the so-called "Baekdudaegan" (BDDG), has been recently suggested to be a major glacial refugium at the Last Glacial Maximum (LGM) for the boreal and temperate flora of northeastern Asia. On the basis of its shared role as a glacial refugium, and on a series of striking similarities in floristic richness and orographic features, the BDDG would constitute a sort of "eastern counterpart" of the Southern Appalachians. Given its floristic, biogeographic, and cultural value, the BDDG merits high priority for conservation.