• Title/Summary/Keyword: IB

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Annealing Behavior of Pretilt Angles on Polyimide Surface with Rubbing and Ion Beam Irradiation

  • Lee, Sang-Keuk;Lim, Ji-Hun;Oh, Byeong-Yun;Kim, Young-Hwan;Han, Jeong-Min;Seo, Dae-Shik
    • Transactions on Electrical and Electronic Materials
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    • v.9 no.6
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    • pp.243-246
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    • 2008
  • We have studied the liquid crystal (LC) alignment, the pretilt angle generation, and the annealing behavior for a nematic liquid crystal (NLC) on the homogeneous polyimide (PI) surfaces by using the rubbing method and the ion beam (IB) method. An excellent LC alignment of the NLC on the PI surface with rubbing and IB irradiation were observed. The pretilt angle of NLC on the homogeneous PI surface for the rubbing method is decreased from $4.5^{\circ}$ to $3.5^{\circ}$ as rubbing time is increased, that of the for the IB irradiation method is decreased from $0.5^{\circ}$ to $0.1^{\circ}$ as the time of IB irradiation is increased. After the annealing, the pretilt angles of the rubbed PI surfaces increased up to $4^{\circ}$, these of the IB irradiated PI surfaces little increased. It is considered the side chain of the rubbed PI show the its abilities of the original capacities, while the side chain of the IB irradiated PI cannot show the its abilities of the original capacities due to the IB has already destroyed the side chain of the PI.

Physicochemical Characteristics and Pharmacokintics of Ibuprofen Lysine Salts (흰쥐에서 이부프로펜 리신염의 물리화학적 특성 및 약물동태에 관한 평가)

  • Shin, Dae-Hwan;Kim, Tai-Sung;Park, Seong-Hyeok;Kim, Si-Hyun;Jo, Han-Jun;Han, Kun;Chung, Youn-Bok
    • YAKHAK HOEJI
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    • v.55 no.3
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    • pp.260-266
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    • 2011
  • Two types of water soluble lysine salts of ibuprofen were prepared and evaluated. Physicochemical properties for ibuprofen-l-lysinate (IBL-l), ibuprofen-dl-lysinate (IBL-dl) and ibuprofen (IB) were studied on melting point, specific ratation, UV spectra and $^1H$-NMR spectra. There were not differences between IBL-dl and IBL-l in UV spectra and $^1H$-NMR spectra. The pharmacokinetic parameters of IB were compared to those of its lysine salts (IBL-l and IBL-dl) after i.v. or oral administration at the dose of 50 mg/kg (calculated as IB). Total body clearance ($CL_t$) and area under the plasma concentration-time curve (AUC) were not different between IB group and IBL groups after i.v. administration. On the other hand, IBL-l and IBL-dl produced peak plasma concentrations ($C_{max}$) significantly ealier and higher than IB. Time to reach peak concentration ($T_{max}$) after IBL administration was lower than that after IB administration. There was no difference in AUC across all different groups (IB, IBL-l and IBL-dl) after oral administration. However, absorption rate constant ($k_a$) of IBL-l and IBL-dl were significantly increased than that of IB. These results indicated that the administration of IBL-l and IBL-dl may be advantageous if rapid and reliable onset of pain relief is required.

Pathological evaluation of renal changes induced by multiple nephropathogenic factors in SPF chickens I. Histopathological and electron microscopical observation (신부전 요인에 의해 유발된 닭 신장변화의 병리학적 관찰 I. 병리조직학적 및 전자현미경적 관찰)

  • Kang, Kyung-il;Mo, In-pil;Kwon, Yong-kuk;Kang, Min-su;Hahn, Tae-wook;Han, Jeong-hee
    • Korean Journal of Veterinary Research
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    • v.39 no.6
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    • pp.1126-1140
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    • 1999
  • Renal failure is one of the main causes of economic impacts in the poultry industry and complex syndrome with different severity of clinical signs caused by multiple nephropathogenic factors such as infectious bronchitis viral infection and excess salt and calcium in diet. To evaluate the correlation between severity of renal failure and the causative nephropathogenic factors, one-day-old specific pathogen free chicks were treated with either single causative factor or multiple causative factors described as above. Each group was designed as control for non-treated control, IB for infectious bronchitis virus (IB virus) infection, IBHNa for IB virus infection with high diet salt, IBHCa for IB virus infection with high diet calcium, IBHNC for IB virus infection with high diet salt and calcium, HNa for high diet salt, HCa for high diet calcium and HNC for high diet salt and calcium. Chickens were inoculated with IB virus at 1-day-old and remained on their respective diets until 21 day of age. The high dietary salt feeding groups such as IBHNa, IBHNC, HNa, HNC increased water intake, watery diarrhea, general subcutaneous edema and the high dietary calcium feeding groups such as IBHCa and IBHNC showed severe visceral gout. Two more than treated groups caused high mortality in comparison with the single treated groups. IB virus exposure significantly increased urate deposition and lymphocytic interstitial nephritis. Especially urate deposition dramatically increased when excess diet calcium was combined together. In excess diet salt treated groups enlarged edematous kidneys were observed and hypertrophy of glomeruli were showed. These results suggest that IB virus enhanced the incidence and severity on chicken renal failure clearly related to the quantity of salt and calcium.

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AN IMMERSED BOUNDARY METHOD FOR LOW REYNOLDS NUMBER FLOWS (저 레이놀즈수에 적용 가능한 가상경계기법)

  • Park, Hyun Wook;Lee, Changhoon;Choi, Jung-Il
    • Journal of computational fluids engineering
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    • v.18 no.3
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    • pp.34-41
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    • 2013
  • We develop a novel immersed boundary (IB) method based on implicit direct forcing scheme for incompressible flows. The proposed IB method is based on an iterative procedure for calculating the direct forcing coupled with the momentum equations in order to satisfy no-slip boundary conditions on IB surfaces. We perform simulations of two-dimensional flows over a circular cylinder for low and moderate Reynolds numbers. The present method shows that the errors for estimated velocities on IB surfaces are significantly reduced even for low Reynolds number with a fairly large time step while the previous methods based on direct forcing failed to provide no-slip boundary conditions on IB surfaces.

The Work Scope of Remodelling for the Intelligent Office Building (기존 사무소건축의 IB화를 위한 리모델링 작업범위)

  • Park, Keun-Joon;Koo, Soo-Young
    • Journal of the Korea Institute of Building Construction
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    • v.4 no.1
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    • pp.75-83
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    • 2004
  • The IB is normally defined in terms of BA, OA, security system, information processing and telecommunications services However, the buildings being already in existence are deficient in two areas. One of these areas is building envelope and plan. The other area is mechanical, electrical and structural systems which do not provide the environmental quality required by IB. Existing technology and design knowledge are available to address these deficiencies. Especially, the office buildings being already in existence must meet IB requirement in order to achieve desirable office environment. They are a building envelope, moisture control, properly-located windows, shafts for duct, telephone and electric closets and acoustical environments. In this paper, a new approach to construct the work scope of remodelling the office building being already existence is described by contrasting the building performance criteria of IB. It concludes by speculating on the consequences of extrapolating the results of study to remodelling the office building being already existence.

Damping-off of Deltoid Synurus Caused by Rhizoctonia solani AG-1 (IB)

  • Kim, Wan-Gyu;Lee, Gyo-Bin;Shim, Hong-Sik;Cho, Weon-Dae
    • The Korean Journal of Mycology
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    • v.49 no.2
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    • pp.249-251
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    • 2021
  • Damping-off symptoms were frequently observed in young deltoid synurus (Synurus deltoides) plants grown in a farmer's vinyl greenhouse located in Hwacheon, Gangwon Province, Korea, during a disease survey in July 2019. The incidence of diseased plants in the vinyl greenhouse investigated was 5-30%. Five isolates of Rhizoctonia sp. were obtained from the diseased plants and identified as Rhizoctonia solani AG-1 (IB), based on morphological and cultural characteristics and anastomosis test results. Three isolates of R. solani AG-1 (IB) were tested for pathogenicity on deltoid synurus using artificial inoculation. All the tested isolates induced damping-off symptoms in the inoculated plants. The symptoms were similar to those observed in plants from the farmer's vinyl greenhouse. To our best knowledge, this is the first report of R. solani AG-1 (IB) causing damping-off in deltoid synurus.

Seedling Rot of Kamchatka Goatsbeard Caused by Rhizoctonia solani AG-1(IB)

  • Wan-Gyu Kim;Gyo-Bin Lee;Hong-Sik Shim;Weon-Dae Cho
    • The Korean Journal of Mycology
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    • v.50 no.4
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    • pp.357-360
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    • 2022
  • In July 2021, we surveyed diseases affecting wild vegetables grown in Hongcheon, Gangwon Province, Korea. During this survey, we observed severe seedling rot symptoms in Kamchatka goatsbeard (Aruncus dioicus) grown in a vinyl greenhouse. The incidence of the disease in the plant seedlings was 1-10%. Diseased seedlings from this population were collected, and fungi were isolated from leaf and petiole lesions. Rhizoctonia sp. was consistently isolated from the lesions. We examined the morphological and cultural characteristics and anastomosis groups of nine Rhizoctonia sp. isolates obtained from the lesions. The results revealed that all isolates corresponded to Rhizoctonia solani AG-1(IB). Three isolates of R. solani AG-1( IB) were evaluated to determine their pathogenicity towards Kamchatka goatsbeard seedlings through artificial inoculation. The tested isolates caused rot symptoms on the inoculated plant seedlings. The symptoms were similar to those observed in plant seedlings from the vinyl greenhouse. We found that R. solani AG-1(IB) caused seedling rot of Kamchatka goatsbeard.

Enhanced Enzyme Activities of Inclusion Bodies of Recombinant ${\beta}$-Galactosidase via the Addition of Inducer Analog after L-Arabinose Induction in the araBAD Promoter System of Escherichia coli

  • Jung, Kyung-Hwan
    • Journal of Microbiology and Biotechnology
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    • v.18 no.3
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    • pp.434-442
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    • 2008
  • We observed that an inclusion body (IB) of recombinant ${\beta}$-galactosidase that was produced by the araBAD promoter system in Escherichia coli (E. coil) showed enzyme activity. In order to improve its activity, the lowering of the transcription rate of the ${\beta}$-galactosidase structural gene was attempted through competition between an inducer (L-arabinose) and an inducer analog (D-fucose). In the deep-well microtiter plate culture and lab-scale fermentor culture, it was demonstrated that the addition of D-fucose caused an improvement in specific ${\beta}$-galactosidase production, although ${\beta}$-galactosidase was produced as an IB. In particular, the addition of D-fucose after induction led to an increase in the specific activity of ${\beta}$-galactosidase IB. Finally, we confirmed that the addition of D-fucose after induction caused changes in the structure of ${\beta}$-galactosidase IB, with higher enzyme activity. Based on these results, we expect that an improved enzyme IB will be used as a biocatalyst of the enzyme bioprocess, because an enzyme IB can be purified easily and has physical durability.

Studies on the Characters of Avian Infectious Bronchitis Virus Isolated in Korea. (국내 분리 닭 전염성 기관지염 바이러스 성상에 관한 연구)

  • 이청산;조우영;최윤식;김순재
    • Korean Journal of Veterinary Service
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    • v.14 no.1
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    • pp.27-40
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    • 1991
  • In order to investigate the biological properties, pathogenicity and immune responses in artficially infected SPF chickens with Avian infectious bronchitis virus that was isolated from chickens showing IB like signs in southern region of Chung buk. Results obtained throuth the experiments are summarized as follows. 1. From 15 IB suspected cases, two strains of IB virus were isolated, one each from the tracheas and lungs. 2. Infectious bronchitis specific embryo lesions were observed after four serial passages of the isolates in chicken embryos. 3. The field isolates and M-41 strain of IB virus interfered with the replication of Newcastle disease virus in chicken embryos. 4. When specific pathogen free chickens, two week old, were inoculated with the IB virus isolates, clinical respiratory signs as dyspnea, coughing were observed. Airsacculitis was observed by necropsy. 5. AGP antibody positive rates of inoculated SPF chickens were highest on day 14 and lowest on day 36, while HI antibody responses were detected on day 14 in all Groups, the reinoculated Group was shown highest titers. 6. By Indirect immunofluorescence antibody assay of artificially infected SPF chickens, the viral antigens were detected in tissues of larynx, trachea and lung on the 4 th to 7 th days post inoculation.

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Fracture Mechanical Fatigue Strength Evaluation of IB-Type Spot Welded Lap Joint under Tension-Shear Load (인장-전단하중을 받는 IB형 일점 Spot 용접이음재의 파괴역학적 피로강도 평가)

  • 손일선;정원석;이휘광;배동호
    • Transactions of the Korean Society of Automotive Engineers
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    • v.6 no.5
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    • pp.20-27
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    • 1998
  • According as the member of the automobile body structure have been thinned their thickness and have become high strength, each part of the body structure has been put more severe stress condition. And, because fatigue strength of the spot welded lap joint is influenced by its geometrical and mechanical factors, welding condition and etc., there needs a quantitative and systematic evaluation method for them. In this study, by considering nugget edge of the spot weld part of the IB-type spot welded lap joint under tension-shear load to the ligament crack. fatigue strength of various IB-type spot welded lap joints was estimated with the stress intensity factor(S.I.F.) KIII which is fracture mechanical parameter. We could find that fatigue strength evaluation of the IB-type spot welded lap joints by KIII is more effective than the maximum principal stress ($\sigma$1max) at edge of the spot weld obtained from FEM analysis.

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