• 한국인쇄학회지
• /
• 제15권2호
• /
• pp.77-90
• /
• 1997

Positive type presensitized offset plate developer were blended by quantitative analysis method. The test had been proceeeded to check variation of developability, shelf life and tone reproduction by SiO2/Na2O ratio to PS plate developer, added glycerin, and sodium phosphate with glycerin. This study of tone reproduction had been tested 5 times to get accuracy by PS platesusing kodak CCG C-3, KMS. The test result of tone reproduction of presensitized offset plates can be summarized as follows ; major compositions in positive type plate developer were Na, Si, K and P, developability were increased by Sio2/NaO2 ratio in positive type plate developer. Shelf life can be kept by add glycerin to positive type plate developer. Tone reproduction were improved by sodium phosphate due to buffer action while shelf life can be kept by add glycerin in positive type plate developer.

• 대한화장품학회지
• /
• 제23권3호
• /
• pp.24-38
• /
• 1997

Using the all-trans-retinol which is double-capsulated with matrix, we investigated its stability and the change of the epidermal thickness. The proprietary MDC comprise two steps of capsulation of retinol, i.e., primary microcapsulation with collagen and then secondary capsulation with gellan gum. We compared the activity of all-trans-retinol in various forms such as (1) simply in O/W, (2) in W/O emulsion, (3) in primary capsulted form in O/W emulsion, or (4) in MDC in O/W emulsion. After storage at 45$^{\circ}C$ for 4 weeks, retinol in MDC in O/W emulsion retained 92% of the activity compared to the standard material upon HPLC analysis, whereas the primary capsule gave 70%, the O/W emulsion form 47% and the W/O emulsion 78%. The retinol in MDC in O/W induced the siginificant increase in epidermal thickness compared to the vehicle.

• 대한한의학회지
• /
• 제21권3호
• /
• pp.174-185
• /
• 2000

Objectives : This study was carried out to evaluate the effects of five fractions on cell viability, cell cycle progression and apoptosis. Methods : This study employed MTT assay, Cell cycle analysis, Cpp32 protease assay, DNA fragmentation assay and Quantitative RT-PCR analysis. Results : In MTT assay, the butanol fraction of Injinsaryung-San has showed magnificent viability, while the $H_2O$ fraction and ethylacetate fraction also showed higher viability than the control group. The $H_2O$ fraction of Injinsaryung-San has showed magnificent viability, and butanol fraction and ethylacetate fraction of Injinsaryung-San with etoposide have also showed higher viability than the only etoposide group. Cell cycle analysis showed that each fraction of Injinsaryung-San had no significant effect on the cell cycle. DNA fragmentation assay showed that the butanol fraction, $H_2O$ fraction and ethylacetate fraction carried inhibitory effects on apoptosis induction. Cpp32 protease activity assay showed that the butanol fraction, $H_2O$ fraction and ethylacetate fraction decreased Cpp32 protease activity, with the butanol fraction displaying greater effects. Quantitative RT-PCR showed that the butanol fraction, $H_2O$ fraction and ethylacetate fraction suppressed Fas and Bax genes, the butanol fraction increased BcI-2 gene, however no effect on Cpp32. Conclusions : The data shows that the butanol fraction of Injinsaryung-San increases the hepatocyte viability and has the heptocelluar protective effect by the suppression of apoptosis through gene regulation.

• 대한화학회지
• /
• 제35권6호
• /
• pp.720-724
• /
• 1991

액상 액체 크로마토그래피(HPLC)에 의해 구절초 중 chlorogenic acid (CA), 3,4-o-dicaffeoyl quinic acid (3,4-DCQA), 4,5-o-dicaffeoyl quinic acid (4,5-DCQA)와 linarin의 동시 정량분석법이 새로히 확립되었다. 시료를 20ml 메탄올로 4시간 추출하고 그 추출물을 Sep-Pak $C_18$ cartridge와 용출액으로 4 ml 메탄올-물(1:1)을 사용해서 분리, 정제하였다. HPLC 정량법으로 Bondapak $C_18$ 컬럼(30 cm ${\times}$ 3.9 mm i.d., 10 ${\mu}m$)과 이동상으로 메탄올 -5mM 인산수용액(30:70)의 기울기 용출방식이 사용되었다. 위 정량분석법을 이용해서 시중 구절초 중 그 함량범위는 CA에서 0.35~0.55%, 3,4-DCQA에서 0.46~0.76%, 4,5-DCQA에서 0.077~0.231% 및 linarin에서 0.16~2.72%이었다.

• 한국재료학회지
• /
• 제32권9호
• /
• pp.384-390
• /
• 2022

A spin coating process for RRAM, which is a TiN/TiO₂/FTO structure based on a PTC sol solution, was developed in this laboratory, a method which enables low-temperature and eco-friendly manufacturing. The RRAM corresponds to an OxRAM that operates through the formation and extinction of conductive filaments. Heat treatment was selected as a method of controlling oxygen vacancy (V_O), a major factor of the conductive filament. It was carried out at 100 ℃ under moisture removal conditions and at 300 ℃ and 500 ℃ for excellent phase stability. XRD analysis confirmed the anatase phase in the thin film increased as the heat treatment increased, and the Ti³⁺ and OH- groups were observed to decrease in the XPS analysis. In the I-V analysis, the device at 100 ℃ showed a low primary SET voltage of 5.1 V and a high ON/OFF ratio of 10⁴. The double-logarithmic plot of the I-V curve confirmed the device at 100 ℃ required a low operating voltage. As a result, the 100 ℃ heat treatment conditions were suitable for the low voltage driving and high ON/OFF ratio of TiN/TiO₂/FTO RRAM devices and these results suggest that the operating voltage and ON/OFF ratio required for OxRAM devices used in various fields under specific heat treatment conditions can be compromised.

• 한국작물학회지
• /
• 제59권4호
• /
• pp.435-444
• /
• 2014

본 연구는 옥수수수염에 함유된 flavonoid 계열의 물질인 maysin, luteolin 7-O-neohesperidoside, luteolin 3'-methyl ether 7-glucuronosyl-($1{\rightarrow}2$)-glucuronide 및 polyphenol성 물질인 chlorogenic acid을 추출 및 분리하는 방법에 관한 것으로, 얻어진 결과를 요약하면 다음과 같다. 1. 수정되지 않은 옥수수수염의 메이신 함량은 출사 후 3일에 함량이 최대치에 도달하고, 그 후 감소되는 것으로 나타났으며, 방임수분된 옥수수수염의 메이신 함량은 출사후 지속적으로 감소되는 것으로 나타나 화분의 수분 여부에 따라 메이신 함량에 많은 차이가 있음을 알 수 있었다. 2. 채취한 옥수수수염에 에탄올을 가하여 9일간 상온에서 추출 후 엽록소, 지질 및 당질 등을 제거시키고, $C_{18}$ column chromatography를 수행하여 분취물 I, II, III, IV를 얻었다. 3. 분취물의 흡광도를 분석한 결과 분취물 I은 327 nm 및 239 nm에서 최대 흡수 파장(${\lambda}_{max}$)을 나타내었고, 분취물 II는 339 nm 및 274 nm, 분취물 III는 345 nm 및 277 nm, 분취물 IV는 352 nm, 270 nm, 및 257 nm 에서 최대 흡수파장을 나타내었다. 4. 분취물 I은 m/z $355[M+H]^+$인 chlorogenic acid(3-(3,4-dihydroxycinnamoyl)quinic acid, $C_{16}H_{18}O_9$)이었으며, 분취물 II는 chlorogenic acid와 m/z $653[M+H]^+$인 luteolin 3'-methyl ether 7-glucuronosyl-($1{\rightarrow}2$)-glucuronide ($C_{28}H_{28}O_{18}$)를 함유한 혼합물, 분취물 III는 chlorogenic acid와 m/z $595[M+H]^+$인 luteolin 7-O-neohesperidoside ($C_{27}H_{30}O_{15}$) 및 luteolin 3'-methyl ether 7-glucuronosyl-($1{\rightarrow}2$)-glucuronide를 함유한 혼합물이었고, 분취물 IV는 m/z $577[M+H]^+$인 maysin ($C_{27}H_{28}O_{14}$, 2"-O-${\alpha}$-L-rhamnosyl-6-C-(6-deoxy-xylo-hexose-4-ulosyl)luteolin 임을 각각 확인 하였다. 5. 옥수수수염의 알코올 추출물로부터 분리된 분취물 I은 옥수수수염 생체 100 g 당 (수분함량 약 92%) 35 mg/100 g, 분취물 II는 48 mg/100 g, 분취물 III는 46 mg/100 g, 분취물 IV는 138 mg/100 g을 얻을 수 있었다.

• Journal of Astronomy and Space Sciences
• /
• 제24권2호
• /
• pp.167-178
• /
• 2007

국보 제230호 송이영(宋以穎)의 혼천시계(渾天時計)는 동아시아에 유일하게 현존하는 혼천시계로서 현재 보존 상태는 부품 일부가 훼손되고 유실되어 작동되지 않고 있다. 우리는 고려대학 박물관에 소장된 이 유물의 학술조사를 수행하여 혼천의 부분의 구조와 원리를 분석하고, 유실된 기계의 태양과 달의 구동장치를 복원하고, 각 부품과 장치를 제작 조립하여 혼천시계의 혼천의 부분의 작동모델을 복원함으로서 천체운행 장치를 작동하게 하였다.

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 1996년도 추계학술대회 논문집
• /
• pp.79-81
• /
• 1996

We fabricated SrTiO$_3$thin film capacitor on the Ag/Si-wafer by RF sputtering deposition. And I-V characteristics and structual analysis of the thin film capacitor are investigated. We found that the leakage current of the films during deposition is strongly denpent on the ambient gas and substrate temperature. Because of increase of activation energy, leakage current increased at high temperature and resistivity of the films was decreased. According to the increase of oxygen gas flow rate, the conductivity of thin film capacitor was increased and leakage current was decreased.

• 한국지능시스템학회:학술대회논문집
• /
• 한국퍼지및지능시스템학회 1993년도 Fifth International Fuzzy Systems Association World Congress 93
• /
• pp.1187-1190
• /
• 1993

The problem of the optimization of fuzzy relational models for dealing with (non-fuzzy) numerical data is investigated. In this context, interfaces optimization assumes particular importance, becoming a determinant factor in what concerns the overall model performance. Considering this, several scenarios for building fuzzy relational models are presented. These are: (i) optimizing I/O interfaces in advance (independently from the linguistic part of the model); (ii) optimizing I/O interfaces in advance and allowing that their optimized parameters may change during the learning of the linguistic part of the model; (iii) build simultaneously both interfaces and the linguistic subsystem; and (iv) build simultaneously both linguistic subsystem and interfaces, now subject to semantic integrity constraints. As linguistic subsystems, both a basic type and an extended versions of fuzzy relation equations are exploited in each one of these scenarios. A comparative analysis of the differ nt approaches is summarized.

• 한국전산유체공학회:학술대회논문집
• /
• 한국전산유체공학회 2003년도 The Fifth Asian Computational Fluid Dynamics Conference
• /
• pp.279-280
• /
• 2003