• Korean Journal of Environmental Biology
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• v.27 no.4
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• pp.391-396
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• 2009

The biological effects of carcinogenic polycyclic aromatic hydrocarbons (cPAHs) including benzo[a]pyrene (BaP), dibenzo[a,h]anthracene (DBA), benzo[a]anthracene (BaA), benzo[b] fluoranthene (BbF), benzo[k]fluoranthene (BkF), and indeno[1,2,3-c, d]pyrene (InP) on transcriptomic changes were determined in the liver of Oryzias latipes. Differentially expressed genes (DEGs) by binary exposure to cPAHs (BaP+BaA, BaP+BbF, BaP+BkF, BaP+DbA, BaP+InP) were screened by annealing control primers-based polymerase chain reaction followed by sequence analysis and BLAST searching. The results showed that four DEGs were commonly expressed by cPAHs and they were identified as ribosomal protein S4, coagulation factor II, elongation factor 1 beta, and a predicted protein similar to human immunodeficiency virus type I enhancer binding protein 3. This finding suggests that binary exposure to cPAHs interferes protein synthesis required for fundamental liver functions in fish.

• Phonetics and Speech Sciences
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• v.2 no.1
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• pp.135-145
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• 2010

This study investigates the differences in mean F0, intensity, jitter, and shimmer across hearing aid, gender, and vowels. For this study, 18 hearing-impaired children, 18 cochlear implanted children, and 18 normal hearing children as a control group were asked to read seven Korean vowels (/$\alpha$, $\wedge$, o, u, w, i, $\varepsilon$/). Subjects' readings were recorded by NasalView and analyzed by Praat. Results showed that the means of F0 were significantly higher in the hearing impaired group than in the normal hearing group; in the female group than in the male group; and in high vowels than in low vowels. Second, intensity was significantly higher in the hearing impaired group than in the normal hearing group; in the female group than in the male group; and in low vowels than in high vowels. Third, jitter was significantly higher in the normal hearing group than in the hearing impaired group; in the female group than in the male group; and in back vowels than in front vowels. Finally, shimmer was significantly higher in the CI group than in the normal hearing group or the hearing aided group; in the male group than in the female group; and in low vowels than in high vowels.

• Phonetics and Speech Sciences
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• v.2 no.4
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• pp.185-192
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• 2010

The acoustic vowel space has been used as an acoustic parameter in dysarthric speech. The aim of this work was to examine mathematical formulae for acoustic vowel space and to apply these to Korean speakers with idiopathic Parkinson's disease(IPD). Five acoustic parameters were chosen from earlier works and one new parameter was proposed, the pentagonal vowel space. The six parameters included triangular vowel space (3 area), irregular quadrilateral vowel space (4 area), irregular pentagonal vowel space (5 area), vowel articulatory index (VAI), formant centralization ratio (FCR) and F2i/F1u ratio (F2 ratio). An experimental group of 32 IPD patients(male:female=16:16) and a control group of twenty healthy people (male:female=8:12) participated in the study and repeated vowels (/a-i-u-e-o/) three times. A correlation analysis was performed among the six parameters, 2-way ANOVA was done with gender and groups as independent factors, and an independent sample t-test was conducted between the male and the female group as post hoc comparison. All parameters were highly correlated with each other and only the FCR showed a high negative correlation with the others. The results of ANOVA showed a significant difference in F2 ratio, 3 area, 4 area and 5 area between gender and in 4 area and 5 area between groups. For the male members of the two groups, significant statistical differences were found in all parameters whereas no such differences were found for the female members. These findings indicated that the vowel space of the female group was wider than the vowel space of the male group. These differences may have been caused by gender-specific speech styles rather than by patho-physiological mechanisms. We also claim that the pentagonal vowel space is better than the other vowel spaces at representing the disordered speech in natural speech situations.

• Journal of Biosystems Engineering
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• v.27 no.2
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• pp.89-96
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• 2002

The trend of consumption of vegetable soybeans is increasing because they are recognized as the clean vegetable. The works requiring the most intensive labor are threshing and seperation ones, and they form about 80% of total labour for vegetable soybeans production. It is necessary to develop the vegetable soybeans-thresher for the sake of cost down of vegetable soybeans production. The purpose of this study is to acquire the basic informations to design of the vegetable soybeans-thresher. We make the experimental system which control the speed of threshing cylinder and the teeth gap and investigate the detachment forces. The result are as follows ; The ratio of un-threshed soybeans-pod to stem after threshing work is decreasing as the threshing cylinder speed increases: 0.0% and 2.8% at 55m/s and 18m/s of threshing cylinder speed respectively. Also the ratio of un-threshed soybeans-pod to stem is shown as 2.0% below in the condition of 64~160mm of teeth gap and over 28m/s of threshing cylinder speed. The damaged pod ratio of detached soybeans after threshing work is decreasing as the threshing cylinder speed increases: 4.8% and 1.3% at 55m/s and 18m/s of threshing cylinder speed respectively. The minimum damaged pod ratio of detached soybeans are shown as 1.0%, 1.5% and 1.9% at 18m/s, 28m/s and 37m/s of threshing cylinder speed respectively. The average detachment forces of pods are shown as 1.5kg$_{f}$ for 3 grains, 1.2kg$_{f}$ for 2 grains and 0.8kg$_{f}$ for 1 grain respectively. The maximum detachment force of pod is shown as 2.7kg$_{f}$ for 3 grains. grains.

• Journal of Convergence for Information Technology
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• v.11 no.2
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• pp.201-210
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• 2021

This study was carried out to investigate the Fagopyrum esculentum (F. esculentum) extracts and vitexin are as the results of microarray, cell proliferation, cell wound recovery, cell cycle, microphage pattern and protein analysis for damage improvement caused by UVB-induced damage. Microarray results showed that UVB-induced increase in DRAM1, Atg2a and Atg13 genes was reduced in F. esculentum ethanol extract and vitexin. Cell proliferation, wound repair, cell cycle, and microphage patterns were improved in F. esculentum ethanol extract and vitexin, while buckwheat ethanol extract and vitexin decreased in both DRAM1, Beclin-1, and LC3 I/II in the vitexin treatment group and p-mTOR and survivin were all increased in protein analysis. It is thought that it can recover to normal and control autophagy, one of the causes of cell aging caused by UVB, to inhibit and regenerate cell death. F. esculentum ethanol extract and vitexin can be used as a functional cosmetic ingredient.

• Progress in Medical Physics
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• v.27 no.3
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• pp.156-161
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• 2016

When air discharged from a radioisotope production facility is contaminated with radiation, the public may be exposed to radiation. The objective of this study is to manage such radiation exposure. We measured the airborne radioactivity concentration at a 30 MeV cyclotron radioisotope production facility to assess whether the exhaust gas was contaminated. Additionally, we investigted the radioactive contamination of the air filter for efficient air purification and radiation safety control. To measure the airborne radiation concentration, specimens were collected weekly for 4 h after the beginning of the radioisotope production. Regarding the air purifier, five specimens were collected at different positions of each filter-pre-filter, high-efficiency particulate air filter, and charcoal filter-installed in the cyclotron production room. The concentrations of F-18, I-123, I-131, and Tl-201 generated in the radioiodine production room were $13.5Bq/m^3$, $27.0Bq/m^3$, $0.10Bq/m^3$, and $11.5Bq/m^3$, respectively; the concentrations of F-18, I-123, and I-131 produced in the radioisotope production room were $0.05Bq/m^3$, $16.1Bq/m^3$, and $0.45Bq/m^3$, correspondingly; and those of F-18, I-123, I-131, and Tl-201 generated in the accelerator room were $2.07Bq/m^3$, $53.0Bq/m^3$, $0.37Bq/m^3$, and $0.15Bq/m^3$, respectively. The maximum radiation concentration of I-123 generated in the radioiodine production room was 1,820 Bq/g, which can be disposed after 2 days. The maximum radiation concentration of Tl-202 generated in the radioisotope production room was 205 Bq/g, and this isotope must be stored for 53 days. The I-123 generated in the radioiodine production room had a maximum concentration of 1,530 Bq/g and must be stored for 2 days. The maximum radiation concentration of Na-22 generated in the radioisotope production room was 0.18 Bq/g and this isotope must be disposed after 827 days. To manage the exhaust, the efficiency of air purification must be enhanced by selecting an air purifier with a long life and determining the appropriate replacement time by examining the differential pressure through systematic measurements of the airborne radiation contamination level.

• Journal of Life Science
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• v.16 no.4
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• pp.632-639
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• 2006

Here we examined the expression patterns and regulation of seven photosynthesis (PS) genes (puf, puc, puhA, bchC, bchE, bchF, and bchI) in the anoxygenic photosynthetic bacterium, Rhodobacter sphaeroides, based on lacZ reporter gene assay. Expression of the tested PS genes, except puhA and bchI, were strongly induced in R. sphaeroides grown under anaerobic conditions relative to that under aerobic conditions. The puhA and bchI genes appear to form the operons together with bchFNBHLM-RSP0290 and crtA, respectively. Expression of the puf, puc, and bchCXYZ operons in R. sphaeroides grown photosynthetically was proportional to the incident light intensity, whereas that of bchFNBHLM(RSP0290-puhA) was inversely related to light intensity. Expression of bchEJG was lowest under medium-light photosynthetic conditions $(10\;W/m^2)$ and highest under high light conditions $(100\;W/m^2)$. The regulation of PS genes by the three major regulatory systems involved in oxygen- and light-sensing in R. sphaeroides is as following: puf and bchC are regulated by both the PpsR repressor and the PrrBA two-component system. The puc operon is under control of PpsR, FnrL, and PrrBA system. Expression of bchE is controlled by FnrL and PrrBA two-component system, whereas bchF is regulated exclusively by PpsR. It was demonstrated that the PpsR repressor is responsible for high-light repression of bchF and that FnrL might be involved in perceiving the cellular redox state in addition to sensing $O_2$ itself.

• 제어로봇시스템학회:학술대회논문집
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• 1993.10b
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• pp.288-292
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• 1993

This paper summerizes a prototype central control system of distribution automation system, which is a result of project carried out by KERI and 6 companies. Of the many possible systems, feeder automation oriented system is described. Control hardware system is composed of one super-mini and 2 workstations. Two kinds of commercial softwares, DBMS and graphic tools, are adopted. Three component system of the hardware has its own role, host system for DB managent, F.A. program running, communication scheduling, and etc., two workstations for communication node and graphic interface node. System management program, feeder automation program including load forcasting, communication scheduling and supervisory contorl functions are developed on the basis of above hardware and properly designed protocol, communication system and terminals.

• Proceedings of the KIEE Conference
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• 1989.07a
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• pp.567-570
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• 1989

A constant V/F control system of voltage contrlled PWM inverter has a unstable operation of the low- speed and the light-load. In this paper, the authors propose stability control with idealized operation of induction motor by the neglect of primary leakage inductance and resistance. Also ldealized operation system is adopted voltage error, feed back impedance circuit, and increasing resistance from dead time of switching is compensated by the soft ware with u-processors. The proposed simulation of the idealized control method is proved at the low-speed operation for three phase induction motor.

• Journal of the Korean Society for Precision Engineering
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• v.18 no.5
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• pp.65-73
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• 2001

In this paper, a mobile system using multi-wheel steering and driving mechanism is proposed to maximize maneuverability of the wheeled mobile system. Among various possible configurations, the two-wheel steering and driving systems, which is minimal in structural requirement, is proposed to reduce the complexity in actual design and difficulties in control. The system possesses three or four degrees of freedom depending on the orientations of two wheels, one or two for driving and two for steering, which implies that the system's mobility is always less than three DOF. The proposed system, nonetheless, can exactly emulate characteristics of the omnidirectional motion as long as the planned path is smooth i.e., the curvature changes continuously while velocity is not zero. Efficient kinematic and dynamic control algorithms are proposed for position and orientation control of the proposed wheeled mobile system.