• Title/Summary/Keyword: I am Sam

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The Microstructures and Hot Extrudability of Semi-solid AM100A Magnesium Alloy Fabricated by Cooling Plate (냉각판으로 제조한 반응고 AM100A 마그네슘 합금의 미세조직 및 열간 압출성)

  • Kim, Dae-Hwan;Sung, Young-Rock;Shim, Sung-Yong;Lee, Sang-Yong;Kim, Kwang-Sam;Lim, Su-Gun
    • Journal of Korea Foundry Society
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    • v.29 no.3
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    • pp.144-149
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    • 2009
  • In this study, we investigated optimum condition of cooling plate method to obtain semi-solid AM100A Mg alloy with fine and globular morphology. AM100A Mg alloy were hot extruded at $380^{\circ}C$ extrusion temperature under extrusion ratio of 25 : 1 and ram speed of 2.4 mm/sec. Vickers hardness test, optical microscopy, scanning electron microscopy, and image analyzer were performed to identify the optimum conditions of cooling plate method. Optimum conditions of cooling plate method to fabricate semi-solid AM100A Mg alloy with fine and globular microstructures were achieved at a pouring temperature of $602^{\circ}C$ and the angle of cooling plate of 60 degree.

The STAR RNA Binding Proteins SAM68, SLM-1 and SLM-2 Interact with Kinesin-I (Kinesin-I과 직접 결합하는 STAR RNA 결합 단백질인 SAM68, SLM-1과 SLM-2의 규명)

  • Seog, Dae-Hyun
    • Journal of Life Science
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    • v.21 no.9
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    • pp.1226-1233
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    • 2011
  • In neurons, kinesin is the molecular motor that transport cargos along microtubules. KIF5s (alias kinesin-I), are heterotetrameric motor conveying cargos, but the mechanism as to how they recognize and bind to a specific cargos has not yet been completely elucidated. To identify the interaction proteins for KIF5C, yeast two-hybrid screening was performed, and specific interaction with the $\underline{S}$am68-$\underline{l}$ike $\underline{m}$ammalian protein $\underline{2}$ (SLM-2), a member of the $\underline{s}$ignal $\underline{t}$ransducers and $\underline{a}$ctivators of $\underline{R}$NA (STAR) family of RNA processing proteins, was found. SLM-2 bound to the carboxyl (C)-terminal region of KIF5C and to other KIF5 members. The C-terminal domain of Sam68, SLM-1, SLM-2 was essential for interaction with KIF5C in the yeast two-hybrid assay. In addition, glutathione S-transferase (GST) pull-downs showed that SAM68, SLM-1, and SLM-2 specifically interacted to Kinesin-I complex. An antibody to SAM68 specifically co-immunoprecipitated SAM68 associated with KIF5s and coprecipitated with a specific set of mRNA. These results suggest that Kinesin-I motor protein transports RNA-associated protein complex in cells.

Inhibitory Effect of Astragaloside I and IV on Passive Cutaneous Anaphylaxis Reaction and Scratching Behaviors in Mice

  • Han, Sang-Jun;Bae, Eun-Ah;Trinh, Hien Trung;Yang, Jung-Hwa;Lee, Eun-Ju;Kang, Sam-Sik;Kim, Dong-Hyun
    • Natural Product Sciences
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    • v.14 no.1
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    • pp.47-50
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    • 2008
  • To evaluate the antiallergic effect of the dried root of Astragalus membranaceus Bunge (AM) (Leguminosae), which inhibited the mouse passive cutaneous anaphylaxis (PCA) reaction in a preliminary experiment, its main constituents, astragalosides I and IV, were isolated and their antiallergic effects were investigated. Astragalosides I and IV inhibited the PCA reaction induced by the IgE-antigen complex, and the scratching behaviors induced by compound 48/80. These constituents reduced the protein expressions of $TNF-{\alpha}$ and IL-4 in IgE-induced RBL-2H3 cells. These findings suggest that astragalosides I and IV as well as AM can improve IgE-induced anaphylaxis and scratching behaviors.

Serotyping and antibiotic susceptibility of Salmonella species from pigs with rectal stricture found in slaughterhouses (도축장 출하 직장협착 돼지에서 분리된 살모넬라균 혈청형 및 항생제 감수성)

  • Jiyeon Kim;Jinju Gwak;Doori Seo;Jaegi Lee;Daewoong Lim;Hana Kim;Jiyeong Park;Jongwoog Choi;Byeongcheol Yoon
    • Korean Journal of Veterinary Service
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    • v.46 no.2
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    • pp.137-145
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    • 2023
  • From November 2021 to October 2022, 151 pigs were discarded due to the suspected salmonellosis, when assessed by antemortem inspection at slaughterhouses in Gwangju. Among them, 85 cases shown with the rectal stricture were confirmed to be infected with Salmonella spp, when assessed by postmortem inspection and Salmonella-oriented culture in the laboratory, accounting for 56.3% of the carcass discard cases. Salmonella spp. were isolated in 58 cases (68.2%) out of 85 total discard cases. As for serotyping of the Salmonella isolates, 28 cases (48.3%) belonged to serogroup B and 28 cases (48.3%) belonged to serogroup C, those were the most frequent isolates, and 2 cases (3.4%) belonged to serogroup E. The most prevalent serotype was Rissen (39.7%), followed by I4,[5],12:i:-(37.9%), Derby (8.6%), Bareilly (5.2%), Infantis (3.4%), Give (3.4%), and Typhimurium (1.7%). The 58 isolates of salmonellae showed resistance to tetracycline (63.8%), chloramphenicol (56.9%), ampicillin (53.4%), and ampicillin-sulbactam (51.7%). S. Rissen showed resistance to chloramphenicol (82.6%), ampicillin (52.2%), ampicillin-sulbactam (52.2%), and tetracyclin (47.8%). S. I4,[5],12:i:-was resistant to tetracycline (90.9%), ampicillin (81.8%), ampicillin-sulbactam (77.3%), and chloramphenicol (59.1%). Among the isoates, S. Bareilly (3 strains), S. Infantis (2 strains), S. Give (2 strains), S. Rissen (3 strains), and S. I4,[5],12:i:- (1 strain) showed no resistance to the tested antimicrobials. As for the prevalence of the antibiotic resistance pattern, AM-SAM-TE-C was the most common, which was shown in 15.5% of S. Rissen. At second, the resistance pattern was occurred as AM-SAM-TE (12.1%) and AM-SAM-CF-CZ-FOX-CTX-NA-TE-C (12.1%), respectively in the case of S. I4,[5],12:i:-.

A Refined Semi-Analytic Sensitivity Study Based on the Mode Decomposition and Neumann Series Expansion (I) - Static Problem - (강체모드분리와 급수전개를 통한 준해석적 민감도 계산 방법의 개선에 관한 연구(I) - 정적 문제 -)

  • Cho, Maeng-Hyo;Kim, Hyun-Gi
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.27 no.4
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    • pp.585-592
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    • 2003
  • Among various sensitivity evaluation techniques, semi-analytical method(SAM) is quite popular since this method is more advantageous than analytical method(AM) and global finite difference method(FDM). However, SAM reveals severe inaccuracy problem when relatively large rigid body motions are identified fur individual elements. Such errors result from the numerical differentiation of the pseudo load vector calculated by the finite difference scheme. In the present study, an iterative method combined with mode decomposition technique is proposed to compute reliable semi-analytical design sensitivities. The improvement of design sensitivities corresponding to the rigid body mode is evaluated by exact differentiation of the rigid body modes and the error of SAM caused by numerical difference scheme is alleviated by using a Von Neumann series approximation considering the higher order terms for the sensitivity derivatives.

The bibliographical study on Pyu-Juk (肺積), Pyu-Ong(肺癰), Pyu-Ju(肺疽), Pyu-Am(肺癌) (폐적(肺積) 폐옹(肺癰) 폐저(肺疽) 폐암(肺癌)에 관(關)한 문헌적(文獻的) 고찰(考察))

  • Han, Jae-Soo;Oh, Tae-Hwan;Jung, Sung-Gi;Rhee, Hyung-Koo
    • The Journal of Internal Korean Medicine
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    • v.12 no.2
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    • pp.113-128
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    • 1991
  • This study has been carried out to investigate Pyu-Juk ( 肺積 ), Pyu-Ong ( 肺癰 ), Pyu-Ju ( 肺疽 ), Pyu-Am ( 肺癌 ) by referring to 56 literatures. The results were obtained as follows; 1. The treatllent-method of Pyu-Juk ( 肺積 ) are Ik Ki ( 益氣 ), SuI Yem Wha ( 洩陰火 ), So Juk ( 消積 ), Wha Juk ( 化積 ), Son Juk ( 損積 ), Ma Juk ( 摩積 ) Jo Chil Gi ( 調七氣 ), and herbs are Sik Bun Tang ( 息賁湯 ), Sik Bun Hwan ( 息賁丸 ), O Juk Hwan ( 五積丸 ), Ban ha Tang ( 半夏湯 ), Gil Gyung Tang ( 桔梗湯 ), Dae Chil Gi Tang ( 大七氣湯 ), Chil Gi Hwan ( 七氣湯 ) , Ga Gam Sik BlDl Hwan ( 加減息賁丸 ), Bil Rang San ( 檳郞散 ). 2. The treatment-method of Pyu-Ong ( 肺癰 ) Yang pyu ( 養肺 ), Yang Hyul ( 養血 ), Yang Gi ( 陽氣 ), Chung Geam Youn Pye ( 淸金潤肺 ), Hal Dam Bae Nong ( 豁痰排膿 ), Saeng Gi ( 生肌 ), herbs are Gil Gyung Tang ( 桔梗湯 ), Jung Ryuk Dae Jo Sa Pyu Tang ( ??大棗瀉肺湯 ), Chung Geom Wy Gyung Tang ( 千金 葦莖湯 ) Hwang Gi tang ( 黃嗜湯 ), Hyun Sam Chung Pyu Eum ( 玄蔘淸肺飮 ), Sip Mi Hwan ( 十味丸 ), Gil Gyung Baek San ( 桔梗白散 ), So Hong Eum ( 消膿飮 ), Sam Gi Bo Pyu Tang ( 蔘嗜補肺湯 ), sam Chul Gun Bi Tang ( 蔘朮健脾湯 ), Chung Pyu Gil Gyung Tang ( 淸肺桔梗湯 ), Yu Sung Hwan ( 如聖丸 ). 3. The treatment-method of Pyu-Ju ( 肺疽 ) are Be Bi ( 補脾 ), Bo Pyu ( 補肺 ), herbs are Hwang Gi Gum Jung Tang( 黃嗜補裨湯 ), lnSamBoPyuSan (人蔘補肺散) 4. The treatment-method of Pyu-Am ( 肺癌 ) are Bal Han ( 發汗 ), Chung Yul Hae Dok ( 淸熱解毒 ), Gang Hwa Do Dam ( 降火導痰 ), Hwa Rak Hwa a ( 和絡化瘀 ) Ik Pyu ( 益肺 ), Gun Bi ( 健脾 ), Ja Eum Yun Pyu ( 滋陰潤肺 ), Gi Hu Yang Bo ( 氣虛兩補 ), herbs are Gyul Yua Hae Dok Tang ( 莖熱解毒湯 ), Gang Hwa Jae ( 降火劑 ), Chil Yul Do Dam Tang ( 治熱導痰湯 ), Chong Ho Byul Gap Tang ( 靑蒿鱉甲湯 ), Ga gam Gil Gyung Tang ( 加減桔梗湯 ), Sang Mak San ( 生脈散), Yuk Mi Ji Hwang Tang ( 六味地黃湯 ), Baek Hap Go Geum Tang ( 百合固金湯 ), Dae Be Won Jun ( 大補元煎 ), Ga Mi Jae Che Bo Pyu Tang ( 加味載體補肺湯 ).

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A study on Critical Thinking Education for Engineering students - Focusing on the Education Using films (공학도를 위한 비판적 사고 교육 연구 - 영화 활용 교육을 중심으로)

  • Hwang, Youngmee
    • Journal of Engineering Education Research
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    • v.21 no.4
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    • pp.3-9
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    • 2018
  • This paper explores the educational method of using films as a means to cultivate critical thinking abilities for engineering students. It provides a practical educational model that elaborates on how films could be used as case studies to draw relevant questions, and in the process of answering them, develop students' ability to think critically. The educational model proposes a learning method of enhancing critical thinking abilities through debates and essay writing on issues raised in films. Furthermore, the paper entails concrete learning objectives on critical thinking education, and standards to evaluate levels of enhancement. Through raising the critical thinking abilities of engineering students, this paper will contribute to the utilization of creative ideas in the process of engineering research. Furthermore, the concept of utilizing films as a model for education used in this study could be adapted for fields other than that of engineering.

The Use of Rasch Model in Developing a Short Form Based on Self-Reported Activity Measure for Low Back Pain

  • Choi, Bong-Sam
    • Physical Therapy Korea
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    • v.21 no.4
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    • pp.56-66
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    • 2014
  • For maintaining adequate psychometric properties when reducing the number of items from an instrument, item level psychometrics is crucial. Strategies such as low item correlation or factor loadings, using classical test theory, have traditionally been advocated. The purpose of this study is to describe the development of a new short form assessing the impact of low back pain on physical activity. Rasch measurement model has been applied to the International Classification of Functioning, Disability and Health Activity Measure (ICF-AM). One hundred and one individuals with low back pain aged 19-89 years (mean age: $48.1{\pm}17.3$) who live in the community were participated in the study. Twenty-seven items of lifting/carrying construct of the ICF-AM were analyzed. Ten items were selected from the construct to create a short form. Item elimination criteria include: 1) high or low mean square (out of the range: .6-1.4 for the fit statistics), 2) similar item calibrations to adjacent items, 3) person separation value, and item-person map for potential gap in person ability continuum. All 10 items of the short form fit to the Rasch model except one item (i.e., carrying toddler on back). Despite its high infit and outfit statistics (1.90/2.17), the item had to be reinstated due to potential gaps at the upper extreme of person ability level. The short form had a slightly better spread of person ability continuum compared to the entire set of item. The created short form separated individuals with low back pain into nearly 4 groups, while the entire set of items separated the individuals into 6 groups. The findings prompted multidimensional models for better explanation of the lifting/carrying domain. The item level psychometrics based on the Rasch model can be useful in developing short forms with rationally retained items.

Transfering and Restoration of Kwon's 'Relief' (권진규 '부조(浮彫)'의 이전 및 복원작업)

  • Kim, Joo Sam
    • 한국문화재보존과학회:학술대회논문집
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    • 2001.11a
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    • pp.35-40
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    • 2001
  • The wall painting and Relief type sculpture were a part of an architecture. Therefore they had better to be preserved in situ, differing with other works of arts. But we confronted inevitable cases to transfer them in appropriate place to conserve. And considering their fragility and a potential danger such as a vibration and shock in process of transfer, we had to do the preventive treatments to prohibit unexpected deteriorations. In this paper, I mention the transferring process when Kwon's 'Relief' was faced to be removed by reconstruction program. A preventive treatment and packaging method were referred in priority.

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Influence of Carrier Trap in InAs/GaAs Quantum-Dot Solar Cells (InAs/GaAs 양자점 태양전지에서 전하트랩의 영향)

  • Han, Im Sik;Kim, Jong Su;Park, Dong Woo;Kim, Jin Soo;Noh, Sam Kyu
    • Journal of the Korean Vacuum Society
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    • v.22 no.1
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    • pp.37-44
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    • 2013
  • In order to investigate an influence of carrier trap by quantum dots (QDs) on the solar parameters, in this study, the $p^+-QD-n/n^+$ solar cells with InAs/GaAs QD active layers are fabricated, and their characteristics are investigated and compared with those of a GaAs matrix solar cell (MSC). Two different types of QD structures, the Stranski-Krastanow (SK) QD and the quasi-monolayer (QML) QD, have been introduced for the QD solar cells, and the parameters (open-circuit voltage ($V_{OC}$), short-cirucuit current ($I_{SC}$), fill factor (FF), conversion efficiency (CE)) are determined from the current-voltage characteristic curves under a standard solar illumination (AM1.5). In SK-QSC, while FF of 80.0% is similar to that of MSC (80.3%), $V_{OC}$ and $J_{SC}$ are reduced by 0.03 V and $2.6mA/cm^2$, respectively. CE is lowered by 2.6% as results of reduced $V_{OC}$ and $J_{SC}$, which is due to a carrier trap into QDs. Though another alternative structure of QML-QD to be expected to relieve the carrier trap have been firstly tried for QSC in this study, it shows negative results contrary to our expectations.