• Archives of Pharmacal Research
• /
• v.26 no.1
• /
• pp.15-20
• /
• 2003

Two quinazolone alkaloids, (+)-febrifugine (1) and isofebrifugine (2), along with three coumarin derivatives, 6-hydroxy coumarin (3), skimmin (5), and $umbelliferone-7-O-{\alpha}-L-rhamnopyranosyl(1{\rightarrow}4)-{\beta}-D-glucopyranoside$ (6), were isolated from the roots of Hydrangea chinensis. Compound 6 is a new compound. In addition, umbelliferone (4), linoleic acid (7), two steroidal glycosides (8, 9), three furfural derivatives (10-12), and butyl-$\beta$-D-fructofuranoside (13) were isolated from the leaves of the same plant. The structures of all isolates were elucidated by spectral methods.

• Korean Journal of Plant Taxonomy
• /
• v.47 no.1
• /
• pp.1-5
• /
• 2017

The population status of Hydrangea luteovenosa Koidz. in Korea was investigated, with an emphasis on its genetic diversity. From field surveys, we obtained the only locality record for a wild population in Jeju Island, which contained 285 individuals in total. Genotyping was performed using five microsatellite markers for the all extant plants in Korea. Three Japanese populations were also genotyped for the comparative analyses. The genotyping result showed that the Jeju population consisted of only two multilocus genotypes, including identical heterozygous genotypes at two loci; it had been maintained mostly by vegetative reproduction; and although the Jeju population is geographically far from Japanese populations, all alleles observed in the Korean population were shared with Japanese populations, suggesting the possibility that H. luteovenosa in the Jeju Island had been recently migrated or introduced from Japan. Future ecological and genetic studies associated with negative effects of low genetic variation will be essential for determining the conservation direction of the threatened Korean population of this species.

• Korean Journal of Plant Taxonomy
• /
• v.43 no.1
• /
• pp.30-33
• /
• 2013

Hydrangea luteovenosa is a critically endangered plant species of Jeju Island in Korea, though it is widely distributed in western Japan. We isolated and characterized five microsatellite loci in this species. The number of alleles ranged from 3 to 27, observed heterozygosity from 0.27 to 0.86, and expected heterozygosity from 0.34 to 0.91. The markers described here will be useful for investigating the genetic diversity, genetic structure, and gene flow of H. luteovenosa, and the genetic findings would contribute to the establishment of effective conservation measures for this species in Korea.

• Journal of Korea Foresty Energy
• /
• v.23 no.1
• /
• pp.38-44
• /
• 2004

The application of the dispersant is indispensable to the manufacture of Korean traditional paper (Hanji). However the mucilage of which extracted from Abelmoschus manihot root has viscosity drop problem in summertime and synthetic dispersant such as polyacrylamide (PAM) and polyethyleneoxide (PEO) have some problems that under the influence of the quality of. water, cohesion, and bad solubility. This study was carried out not only to develop new natural dispersant that can solve such problems but also to investigate the viscosity and papermaking characteristics of Hydrangea paniculata mucilage. There were no viscosity changes between control and treated mucilage that adjusted to pH 9, heated 6 hours at 40 $^{\circ}C$, and stored heating treatment one for a week at 5 $^{\circ}C$. The treatment of mucilage that adjusted to pH 9 and aged for 120 hours at 4$0^{\circ}C$ resulted in viscosity drop. In the hydrolysis of mucilage, galacturonic acid and glucuronic acid contents were decreased by heating and pH adjusting treatments. Wet web stripping quality and physical properties of Korean traditional paper, which used Hydrangea paniculatamucilage were same or superior to the Abelmoschus manihot root.

• Journal of People, Plants, and Environment
• /
• v.22 no.2
• /
• pp.145-157
• /
• 2019

This study was conducted to examine the effects of horticultural therapy on depression and emotional balance of women with hearing impairment. Ten women with hearing impairment registered in the Mokpo branch of the Korean Association of the Hearing Impaired were selected, and participated in the horticultural therapy program composed of 14 sessions from May 15 to July 31. The horticultural therapy program consisted of 'planting tropical orchids,' 'making a dish garden,' 'making plum pickles,' 'decorating a table with flowers,' 'making a hanging pot with succulent plants,' 'making pressed flowers with hydrangea,' 'making a fan with pressed flowers,' 'making a terrarium,' 'making a flower basket,' 'making a mosquito repellent spray,' 'decorating a heart-shaped cup with flowers,' 'making a natural herbal soap,' 'making a hydrangea bouquet' and 'making watermelon salad.' The depression and emotional balance scales were used to examine the effects of the program and the pre- and post-program scores were compared. The mean value of depression statistically significantly decreased from 49.0 points before the program to 43.9 points after the program. In addition, the mean value of emotional balance statistically significantly increased from 0.3 points before the program to 2.3 points after the program. The activity of drawing a picture after each session was effective in reducing depression and improving positive emotional balance by expressing emotions through pictures. The programs preferred by women with hearing impairment included 'making plum pickles,' 'making pressed flowers with hydrangea,' 'planting tropical orchids,' 'making a mosquito repellent spray,' 'making a natural herbal soap,' and 'making watermelon salad.' In conclusion, horticultural therapy programs were effective in reducing depression and improving emotional balance of women with hearing impairment.

• Journal of Life Science
• /
• v.27 no.3
• /
• pp.355-360
• /
• 2017

Consumption of high doses of ethanol can lead to amnesia, which often manifests as a blackout. This incoordination of blackout may be a major cause in various social problems in alcohol consumption. However, there is still no treatment for preventing these alcohol-induced problems. Hydrangeae dulcis folium is a drug or a tea which is made from the fermented and dried leaves of Hydrangea serrata Seringe. The present study, we tested the ethanol extract of the Hydrangeae dulcis folium (EHDF) on ethanol-induced psychological deficits. To test behavioral deficits, an object recognition test was conducted using a mouse model. To evaluate synaptic deficits, N-methyl-D-aspartate (NMDA) receptor-mediated excitatory postsynaptic potential EPSP and long-term potentiation (LTP) in the mouse hippocampal slices were tested, as they are known to be vulnerable to ethanol and are associated with ethanol-induced amnesia. In the tests, ethanol (1 g/kg, i.p.) impaired object recognition memory, but EHDF (10 or 30 mg/kg) prevented this impairment in object recognition test. Interestingly, EHDF ($30{\mu}g/ml$) significantly ameliorated ethanol-induced LTP and NMDA receptor-mediated synaptic transmission in the hippocampal slices. EHDF prevented ethanol-induced object recognition memory deficits induced by ethanol. Interestingly, EHDF significantly ameliorated ethanol-induced LTP and NMDA receptor- mediated synaptic transmission in the hippocampal slices.

• Proceedings of the Korean Nutrition Society Conference
• /
• 2003.05a
• /
• pp.307.1-307.1
• /
• 2003

• Proceedings of the Korean Nutrition Society Conference
• /
• 2003.05a
• /
• pp.307.2-307.2
• /
• 2003

• Journal of Pharmacopuncture
• /
• v.21 no.2
• /
• pp.82-89
• /
• 2018

Objective: Diabetes mellitus (DM) is the most common metabolic disorder that defined by chronic hyperglycemia for the deficiency in insulin secretion or resistance. Hyperglycemia could induce non-enzymatic glycation of proteins. It has been suggested that some traditional plants can improve blood glucose and inhibit glycation process. This work evaluates and compares the anti-glycation activities of four Iranian plant extracts in vitro. Methods: The methanolic extract of "Fumaria officinalis, Stachys lavandulifolia, Salvia hydrangea and Rosa Damascene" was prepared in three different concentrations. Phenolic, flavonoids content and antioxidant activity were evaluated. The multistage glycation markers- fructosamines (early stage), protein carbonyls (intermediate stage) and ${\beta}$ aggregation of albumin were investigated in the bovine serum albumin (BSA)/ glucose systemt. Results: All plants showed the high potency of scavenging free radicals and glycation inhibition in the following order: Fumaria officinalis> Rosa Damascene> Stachys lavandulifolia > Salvia hydrangea. There was a significant correlation between antioxidant and anti-glycation activity. Also, the antioxidant and anti-glycation capacity of extracts correlated with total phenolic and flavonoids content. Conclusion: Our findings demonstrated that the studied plants are good sources of anti-glycation and antioxidant compounds and, these properties can primarily attributable to phenolics, particularly flavonoids.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2019.10a
• /
• pp.22-22
• /
• 2019

수국속(Hydrangea L.)은 APG IV분류체계에 따르면 국화군(Asterids), 층층나무목(Cornales), 수국과(Hydrangeaceae)에 속하는 식물로서 동아시아, 북아메리카 동부 지역을 중심으로 분포하며 전 세계에 23여종이 알려져 있다. 한국산 수국속은 Nakai가 H. hortensia var. acuminata의 분포를 기록함으로써 시작되었다. 이후 Nakai는 산수국을 H. acuminata로 재처리, 다시 H. serrata var. acuminata로 변경하였다. 한편 산수국은 분류학적 위치에 대한 이견이 있다. Wilson은 수국과 산수국을 가까운 유연관계를 가지는 독립된 분류군으로 분류하였지만, Makino는 산수국을 수국의 아종인 H. marcrophylla subsp. serrta로 기재하는 등 산수국과 수국의 동정과 계급설정에 혼란이 있는 가운데, 최근 천연물 hydrangenol을 활용한 건강기능식품 개발에서 사용가능 재료의 한계를 설정하기 위한 산수국과 수국에 대한 종 설정 연구도 요구되고 있다. 따라서 본 연구에서는 nrDNA ITS, trnL-F, trnC-ycf6의 3개 구간의 DNA sequence와 NCBI (National Center for Biotechnology Information)를 참고한 분자생물학적 분석결과와 외부형태학적 재검토 결과를 통하여 H. marcrophylla를 종(Species)으로서의 분류학적 위치 지지하며 또한 수국과 산수국을 가까운 유연관계를 가지는 독립된 분류군으로 분류한 의견을 지지하는 결과를 도출하였다. 향후 hydrangenol 활용의 기초정보로 활용되기를 기대한다.