• 제목/요약/키워드: Hwang Jin-yi

검색결과 181건 처리시간 0.036초

Determination of a Novel Antiangiogenic Agent KR-31831 in Rat Plasma by Liquid Chromatography-Tandem Mass Spectrometry

  • Kim, Sook-Jin;Lee, Seung-Seok;Ji, Hye-Young;Lee, Hong-Il;Lee, Seon-Kyoung;Yi, Kyu-Yang;Yoo, Seong-Eun;Hwang, Jeong-Sook;Lee, Hye-Suk
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.217.2-217.2
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    • 2003
  • A liquid chromatography-tandem mass spectrometric (LC/MS/MS) method was developed for the determination of a new anti-angiogenic drug KR-31831 in rat plasma. KR-31831 and internal standard, KR-31543 were extracted from rat plasma with dichloromethane at basic pH. A reverse-phase LC separation was performed on Luna C8 column with the mixture of acetonitrile-ammonium formate (10 mM, pH 4.5) (67:33, v/v) as mobile phase. The detection of analytes was performed using an electrospray ionization tandem mass spectrometry in the multiple-reaction-monitoring mode. (omitted)

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유아용 한방 스킨제어제품이 유아 피부의 보습 효능에 미치는 영향 (The Moisturizing Effects of the Cosmetic Products Containing Herbs Extract on Infant Skin)

  • 이재근;이진상;박현진;조원준;김미려;하일도;김광중;황순이;지선영
    • 한방안이비인후피부과학회지
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    • 제21권3호
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    • pp.124-131
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    • 2008
  • Objectives : The aim of this study was conducted to test dry infant skin by external application with herbs in cosmetics. Methods : A total of 25 infants who visited Daegu Hanny Oriental Medical Center from March 5th, 2008 to May 18th, 2008 were included in this study. In this study, they were treated with the cosmetic products(body wash, rotion, cream) containing herbs. For 4 weaks skin moisture content was measured by corneometer ClVI825. And satisfaction after using body wash, rotion, cream was checked. Results : There were no significant differences on sex and age. Change of skin moisture content between before treatment and after treatment (2, 4 weeks) showed significant changes(p<0.05). Satisfaction after using body wash, rotion, cream was near good. Conclusions : Considering the above results, we have concluded that cosmetics containing herbs have the remarkable effect on infant skin mosturizing.

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자기카메라에 의한 고속철도 차륜의 구름접촉 피로평가 (Evaluation of Rolling Contact Fatigue Evaluation of Wheel for High Speed Train Using a Scan Type Magnetic Camera)

  • 황지성;권석진;이진이;서정원
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2011년도 정기총회 및 추계학술대회 논문집
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    • pp.957-965
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    • 2011
  • Recently, railway industry has been developed not only functional parts such as acceleration and high performance of the railway but also emotional parts such as improved ride comfort and blocking noise. However, some important components of railway such as wheel and rail always had exposed too much operation time, cyclic load and rolling contact directly. The variations of load, vibration and chemical compositions were caused of wheel and rail having a lot of different types of contact fatigue damages. Therefore, It is necessary to improve inspection and maintenance technology in order to ensure safety and reliability of railway. Many researchers have already been reported the technology. Magnetic camera, one of the non-destructive testing technique can be used to inspect and evaluate the changes of magnetic field in ferromagnetic and paramagnetic materials with cracks. When an electromagnetic is applied to a specimen, a magnetic field will be distorted around a crack on the specimen. In present paper, the distribution of magnetic property in wheel with cracks using magnetic camera had investigated. The crack can be detected and evaluated by distribution analysis of magnetic field. The magnetic camera technique can be detected and evaluated the crack by rolling contact fatigue.

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반응소결 SiC 재료의 제조 및 특성 (Fabrication and Characterization of Reaction Sintered SiC Based Materials)

  • 진준옥;이상필;박이현;황희진;윤한기
    • 한국해양공학회:학술대회논문집
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    • 한국해양공학회 2003년도 춘계학술대회 논문집
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    • pp.294-299
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    • 2003
  • The efficiency of complex slurry preparation route for the development of high performance RS-SiCf/SiC composites has been investigated. The green bodies for RS-SiC and RS-SiCf/SiC composite materials prior to the infiltration of molten silicon were prepared with various C/SiC complex matrix slurries, which associated with both different sizes of starting SiC particles and blending ratios of starting SiC and carbon particles. The reinforcing materials in the composite system were uncoated and C coated Tyranno SA SiC fiber. The characterization of RS-SiC and RS-SiCf/SiC composite materials was examined by means of SEM, EDS and three point bending test. Based on the mechanical property-microstructure correlation, process optimization methodology is discussed.

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시조를 활용한 감정 비율의 문학생리학 (Literary Physiology of an Emotional Ratio Using Sijo)

  • 박인과
    • 문화기술의 융합
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    • 제5권2호
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    • pp.305-311
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    • 2019
  • 삶의 치유는 무덤으로 통할까, 아니면 죽음이 삶을 치유할 수 있을까. 삶에 있어서의 치유는 삶의 공간의 감정 회로에 존재한다. 그러면 죽음에서의 치유는 어떤 공간에 존재할까. 일단은 죽음에서의 치유는 삶의 너머에 있다. 임제(林悌, 1549~1587)는 그가 사랑하는 황진이의 무덤에서 슬픔의 시조를 읊은 것으로 유명하다. 문학치료를 위해, 이번에는 임제가 황진이의 무덤에서 읊었다고 하는 시조 "청초 우거진 골"의 감정들을 코딩하려고 한다. 이 시조는 사랑과 죽음, 무덤과 슬픔이라는 고통같은 슬픔의 사랑을 노래한다. 즉 사랑과 아픔 혹은 사랑과 이별이라는 상반된 개념이 일으키는 인간의 감정이 어떻게 융합하는지에 관련된 것이다. 임제의 이 시조는 무덤과 사랑과 슬픔이라는 기표들을 융합하여 '인생의 무상함'을 코딩한다. 이 '인생의 무상함'이 이 시조의 문학치료 기능이다. '인생의 무상함'은 인체의 긴장을 풀어주는 치유의 역할을 한다. 이렇게 문학치료가 이루어지면 아무리 고통스러운 삶이라도 우리들은 여유를 가지게 된다. 이 시조에서 전달하는 '인생의 무상함'에 대한 슬픔이 삶 전체를 관조하며 관용하는 문학치료의 효과를 전달하기 때문이다. 앞으로 이러한 연구를 지속하여 새로운 삶에 대한 감정 코딩이 이루어지길 기대한다.

위증(?證)에 관(關)한 문헌적(文獻的) 고찰(考察) -병인병기(病因病氣), 치법(治法) 및 치방(治方) 중심(中心)으로 - (A literatural study on the atrophy syndrome(?證))

  • 김성수;금동호
    • 동국한의학연구소논문집
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    • 제7권2호
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    • pp.81-95
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    • 1999
  • 위증(?證)과 이완성 마비는 각각 한의학과 서양의학에서 쓰여지는 증상의 개념이지만 두개의 개념간에는 많은 유사점이 있다. 즉, 용어가 조금 다를 뿐이지 지체(肢體)가 위약(委弱)하여 잘 쓰지 못하여 수의적인 운동이 잘 되지 않는 것을 가리키는 개념임을 알 수가 있다. 이 위증(?證) 이완성 마비는 양측성(兩側性), 상행성(上行性)이라는 특징을 가지고 있어서 편측성(片側性) 및 상하지(上下肢) 동시에 증상이 종종 발현하는 중풍의 후유증과 서로 다름에도 불구하고 실제 임상에는 같은 것으로 오인(誤認)되는 경우가 많아 이에 대한 감별이 필요하다. 이 고찰(考察)에서는 역대의 중요 문헌을 통하여 위증의 병인병기(病因病機) 및 치법치방(治法治方)과 치방(治方)의 빈도(頻度)를 각 시대별 대표적인 의가(醫家)의 순(順)으로 정리함으로써 위증의 이해를 넓히는데 도움이 되도륵 하였다. 따라서 위증에 대한 정확한 인식과 임상활용의 기초자료를 얻고자 고찰(考察)하여 보고하는 바이다.

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1970년대 초 한국영화의 여성 재현 : 사회적 콘텍스트와의 연관성을 중심으로 (Representation of Women in Early 1970's Korean Films : focusing on the relationship with social contexts)

  • 황혜진
    • 만화애니메이션 연구
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    • 통권17호
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    • pp.117-132
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    • 2009
  • 이 논문은 유신체제 출범 직전인 1972년 제작, 개봉된 <모범운전사 갑순이>와 <쥐띠부인>의 여성 재현방식을 분석하였다. 두 영화는 각각 관습화된 오락영화의 약호를 이용하여 대중에게 소구함으로써 유신체제 이후의 본격적인 국책영화와 거리를 두고 있다. 그러나 실제 텍스트 내부를 보면, 지배 이데올로기를 내면화한 여성 주인공을 통해 급속한 근대화가 초래한 모순들을 봉합하고 있음을 알 수 있다. 이것은 국가가 주도하는 근대화 기획이 요구하는 이상적 여성을 스테레오 타입화함으로써 여성관객들로 하여금 국가동원체제에 순응하는 새로운 집단 정체성을 구성하도록 하기 위한 전략이라고 할 수 있다.

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Enhanced Electron Emission of Carbon Nanotube Arrays Grown Using the Resist-Protection-assisted Positioning Technique

  • Ryu, Je-Hwang;Kim, Ki-Seo;Yu, Yi-Yin;Lee, Chang-Seok;Lee, Yi-Sang;Jang, Jin;Park, Kyu-Chang
    • Journal of Information Display
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    • 제9권4호
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    • pp.30-34
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    • 2008
  • Field emitter arrays (FEAs) were developed using carbon nanotubes (CNTs) as electron emission sources. The CNTs were grown using a selective-positioning technique with a resist-protection layer. The light emission properties were studied through the electron emission of the CNTs on patterned islands, which were modulated with island diameter and spacing. The electron emission of CNT arrays with $5{\mu}m$ diameters and $10{\mu}m$ heights increased with increased spacing (from $10{\mu}m$ to $40{\mu}m$). The electron emission current of the $40-{\mu}m$-island-spacing sample showed a current density of 1.33 mA/$cm^2$ at E = 11 V/${\mu}m$, and a turn-on field of 7 V/${\mu}m$ at $1{\mu}A$ emission current. Uniform electron emission current and light emission were achieved with $40{\mu}m$ island spacing and $5{\mu}m$ island diameter.

태음형(太陰形)에 관한 형상의학적 고찰 (Perspective on Taeum Type in Hyungsang Medicine)

  • 김종원;옥진아;전수형;강경화;석화준;김규곤;이용태
    • 동의생리병리학회지
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    • 제23권3호
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    • pp.521-527
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    • 2009
  • According to <> and <>, Taeum is strongly related to dampness, earth, and canter. The origin of Taeum is dampness and the presentation of it is dryness, thus spleen plays a greater role than lung in physiologic and pathologic aspect. Taeum meridian cooperates with Soeum and Guelum meridian, and spreads yin gi through spleen and lung meridian. Among six meridian types that are invented by Ji-San, Taeum type possesses lowered eyes and nose and displays characteristics of Taeum disease. Instead of five jang organs and six bu orqans, meridians are major factor of Taeum type. Thus SiDongByung (disease of gi) and SoSaengByung (disease of blood) are considered more significantly than internal and external symptoms of organs. Personality of Taeum type is realistic, pragmatic, diligent, and occasionally selfish. Medications for Taeum type are described as following. GwakHyangJungKi-San or InSamYangWi-Tang can be considered for the complication of intrinsic and extrinsic diseases, which are caused by yin symptom of SangHan. If cold stomach affected by Taeum disease causes an abdominal pain and diarrhea, YiJoong-Tang or PalMiYiJoong-Tang are suggested.

18인(人)의 비증(痺證) 논술(論述)에 대(對)한 연구(硏究) - 《비증전집(痺證專輯)》 에 대(對)한 연구(硏究) II - (Study of BiJeung by 18 doctors - Study of II -)

  • 손동우;오민석
    • 혜화의학회지
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    • 제9권1호
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    • pp.595-646
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    • 2000
  • I. Introduction Bi(痺) means blocking. BiJeung is one kind of symptoms making muscles, bones and jonts feel pain, numbness or edema. For example it can be gout or SLE etc. says that Bi is combination of PungHanSeup. And many doctors said that BiJeung is caused by food, fatigue, sex, stress and change of weather. Therefore we must treat BiJeung by character of patients and characteristic of the disease. Many famous doctors studied medical science by their fathers or teachers. So the history of medical science is long. So I studied ${\ll}Bijeungjujip{\gg}$. II. Final Decision 1. JoGeumTak(趙金鐸) devided BiJeung into Pung, Han, Seup and EumHeo, HeulHeo, YangHeo, GanSinHeo by charcter or reaction of pain. And he use DaeJinGyoTang, GyegiGakYakJiMoTang, SamyoSan, etc. 2. JangPaeGyeu(張沛圭) focused on division of HanYeol(寒熱; coldness and heat) in spite of complexity of BiJeung. He also used insects for treatment. They are very useful for treatment of BiJeung because they can remove EoHyeol(瘀血). 3. SeolMaeng(薛盟) said that the actual cause of BiJeung is Seup. So he thought that BiJeung can be divided into PungSeup, SeupYeol, HanSeup. And he established 6 rules to treat BiJeung and he studied herbs. 4. JangGi(張琪) introduced 10 prescriptions and 10 rules to cure BiJeung. The 1st prescription is for OyeSa, 2nd for internal Yeol, 3rd for old BiJeung, 4th for Soothing muscles, 5th for HanSeup, 6th for regular BiJeung, 7th for functional disorder, 8th for YeolBi, 9th for joint pain and 10th for pain of lower limb. 5. GangSeYoung(江世英) used PungYeongTang(風靈湯) for the treatment of PungBi, OGyeHeukHoTang(烏桂黑虎湯) for HanBi, BangGiMokGwaTang(防己木瓜湯) for SeupBi, YeolBiTang(熱痺湯) for YeolBi, WoDaeRyeokTang(牛大力湯) for GiHei, HyeolPungGeunTang(血楓根湯) for HyeolHeo, ToJiRyongTang(土地龍湯) for the acute stage of SeupBi, OJoRyongTang(五爪龍湯) for the chronic stage of SeupBi, and so on. 6. ShiGeumMook(施今墨) devided BiJeung into four types. They are PungSeupYeol, PungHanSeup, GiHyeolSil(氣血實) and GiHyeolHeo(氣血虛). And he introduced the eight rules of the treatment(SanPun(散風), ChukHan(逐寒), GeoSeuP(, CheongYeol(淸熱), TongRak(通絡), HwalHyeol(活血), HaengGi(行氣), BoHeo(補虛)). 7. WangYiYou(王李儒) explained the acute athritis and said that it can be applicable to HaneBi(行痺). And he used GyeJiJakYakJiMoTang(桂枝芍蘂知母湯) for HanBi and YeolBiJinTongTang(熱痺鎭痛湯) for YeolBi. 8. JangJinYeo(章眞如) said that YeolBi is more common than HanBi. The sympthoms of YeolBi are severe pain, fever, dried tongue, insomnia, etc. And he devided YeolBi into SilYeol and HeoYeol. In case of SilYeol, he used GyeoJiTangHapBaekHoTang(桂枝湯合白虎湯) and in case of HeoYeol he used JaEumYangAekTang(滋陰養液湯). 9. SaHaeJu(謝海洲) introduced three important rules of treatment and four appropriate rules of treatment of BiJeung. 10. YouDoJu(劉渡舟) said that YeolBi is more common than HanBi. He used GaGamMokBanGiTang(加減木防已湯) for YeolBi, GyeJiJakYakJiMoTang or GyeJiBuJaTang(桂枝附子湯) for HanBi and WooHwangHwan(牛黃丸) for the joint pain. 11. GangYiSon(江爾遜) focused on the internal cause. The most important internal cause is JeongGiHeo(正氣虛). So he tried to treat BiJeung by means of balance of Gi and Hyeol. So he ususlly used ODuTang(烏頭湯) and SamHwangTang(三黃湯) for YeolBi, OJeokSan(五積散) for HanBi, SamBiTang(三痺湯) for the chronic BiJeung. 12. HoGeonHwa(胡建華) said that to distinguish YeolBi from Hanbi is very difficult. So he used GyeJiJakYakJiMoTang in case of mixture of HanBi and YeoBi. 13. PiBokGo(畢福高) said that the most common BiJeung is HanBi. He usually used acupuncture with medicine. He followed the theory of EumYongHwa(嚴用和)-he focused on SeonBoHuSa(先補後瀉). 14. ChoiMunBin(崔文彬) used GeoPungHwalHyeolTang(祛風活血湯) for HanBi, SanHanTongRakTang(散寒通絡湯) for TongBi(痛痺), LiSeupHwaRakTang(利濕和絡湯) for ChakBi(着痺), CheongYeolTongGyeolChukBiTang(淸熱通經逐痺湯) for YeolBi(熱痺) and GeoPungHwalHyeolTang(祛風活血湯) for PiBi(皮痺). 15. YouleokSeon(劉赤選) introduced the common principle for the treatment of BiJeung. He used HaePuneDeungTang(海風藤湯) for HaengBi(行痺), SinChakTang(腎着湯), DokHwalGiSaengTang(獨活寄生湯) for TongBi(痛痺), TongPungBang(痛風方) for ChakBi(着痺) and SangGiYiMiTangGaYeongYangGakTang(桑枝苡米湯加羚羊角骨) for YeolBi(熱痺). 16. LimHakHwa(林鶴和) said about TanTan(movement disorders or numbness) and devided TanTan into the acute stage and the chronic stage. He used acupuncture at the meridian spot like YeolGyeol(列缺), HapGok(合谷), etc. And he also used MaHwangBuJaSeSinTang(麻黃附子細辛湯) in case of the acute stage. In the chronic stage he used BangPungTang(防風湯). 17. JinBaekGeun(陳伯勤) liked to use three rules(HwaHyeol(活血), ChiDam(治痰), BoSin(補腎)) to treat BiJeung. He used JinTongSan(鎭痛散) for the purpose of HwalHyeol(活血), SoHwalRakDan(小活絡丹) for ChiDam(治痰) and DokHwalGiSaengTang(獨活寄生湯) for BoSin(補腎). 18. YimGyeHak(任繼學) focused on YangHyeolJoGi(養血調氣) if the stage of BiJeung is chronic. And in the chronic stage he insisted on not using GalHwal(羌活), DokHwal(獨活) and BangPung(防風).

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