• Archives of Plastic Surgery
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• 제36권5호
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• pp.611-616
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• 2009

Purpose: The rate of fistulas occuring followed by resection of oral cavity, oropharyngeal, hypopharyngeal, and laryngeal cancer are reported to be 9 ~ 23% according to various documents. Neglected treatment of the fistula can result in a setback in proper treatment with restrictions in oral intake leading to delayed return to daily life. Furthurmore, in severe cases, it may injure important vessels and adjacent structures of the neck area. The author reviewed previously reported cases of treatment methods for fistulas recurring after diverse head and neck operations and with sharing the treatment experiments of our patients, we tried to present a treatment algorism for different fistula types. Methods: Our study was based on retrograde analysis of 64 patients who were clinically diagnosed with fistula after operation for cancer of the head and neck from 1997 to 2008 at Severance Hospital. Their primary sites of cancer were 8 oral cavity, 22 oropharynx, 25 hypopharynx, and 9 larynx. The patients were aged 45 to 75 years and the male to female ratio was 11 to 1. The patient's operation records and progress notes were evaluated for determination of degree of fistula and treatment methods. Results: Most fistulas were clinically suspected after postoperative 5 days and symptoms noted for detection of the fistula were erythema, purulent discharge, edema, tenderness, and fluctuation. The fistula was definitely diagnosed at postoperative 2 weeks with barium test and treatment method ranging from conservative management to operative procedure were applied to each patients. Total 21 patients were managed with conservative protocol. In 15 cases, direct repair of the fistula was done and more stable repair of the fistula was possible with using of TachoComb$^{(R)}$. Pharyngostoma was performed in 14 patients. Among them, 4 patients healed spontaneously, 5 patients were taken direct closure, 4 patients were taken pectoralis major musculocutaneous flap, and one patient was taken esophageal transfer. The other 14 patients were taken 11 pectoralis major musculocutaneous flaps and 3 free flaps without pharyngostoma formation. Conclusion: Fistula is a troublesome complication resulting after resection of head and neck cancer. Early detection and adequate treatment according to the period and condition of the fistula may prevent further complications and reduce the pain of the patient.

• 한국의류산업학회지
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• 제17권4호
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• pp.646-656
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• 2015

This study investigates the conditions of Korean naval duty and combat uniforms to develop a new design. Survey participants consisted of, 723 Sailors ($25.3{\pm}6.9yr$ in age, $43{\pm}53$ months in work experience, $174{\pm}6cm$ in height, $71{\pm}9kg$ in body mass) serving in the Korean Navy for over 12 months. The questionnaire consisted of 72 questions about anthropometric characteristics, preferred design, textiles, wear mobility, and subjective perceptions. The results showed that the preferred colors for future naval duty uniforms were blue in summer (69%) and black in winter (62%). Digital camouflage pattern (60%) and darker colors on the inside of shirt collar (87%) and the edge of sleeves (84%) were preferred. They favored more than one pocket on the upper arm and chest of the shirts (58%), narrower width around pant legs and hems than the current clothing (63%), self-controlled elastic waist (55%) and no cargo type pocket on the pants (45%). There were requirements to alleviate excessive heat stress in summer and to protect from the cold and wind in winter. Wrinkle-free (85%), anti-bacterial (78%), water-proof (75%), oil-proof (90%), and elastic (67%) textiles were preferred for Korean navy uniforms. These results will be applied to develop the next generation Korean navy uniforms.

• Journal of Dairy Science and Biotechnology
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• 제35권3호
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• pp.169-175
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• 2017

Recently, the health-promoting effects of functional foods have been shown to prevent nutrition-related diseases, improve physical and mental well-being, satisfy hunger, and provide necessary nutrients for the human body. Koumiss is a common type of fermented mare's milk that has been shown to have beneficial therapeutic effects on cardiovascular disease, tuberculosis, and diarrhea as it can nourish vessels, relieve ill mood, and improve digestion. Hence, in this study, we aimed to prepare health-promoting koumiss using different concentrations of flaxseed (Linum usitatissimmum L.), which has the potential to control heart disease, hypertension, inflammation, and lung function. The pH was decreased to around 4.42-4.43, whereas the total anthocyanin (TA) content was increased to around 0.78~0.82% after fermentation of the koumiss premix. There were no significant differences in pH and TA among the three groups, including the control group. In sensory profile analysis, the taste, flavor, color, texture, and overall acceptability decreased in proportion to the added amount of flaxseed. These findings provided the first data describing the effects of flaxseed on koumiss fermentation, establishing a basis for commercial-scale production of koumiss containing fermented flax seed and for improving the health-promoting activity of koumiss.

• 한국항해학회지
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• 제9권1호
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• pp.1-40
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• 1985

The transport of cargoes carried by coastal and ocean-going vessels has increased with the rapid growth of the Korean economy these days. This increase of the sea-borne cargoes has made the Korean coastal traffic so congested that this can be a cause of large pollution as well as great marine casualties such as loss of human lives and properties. Marine casualties generally result from the complicated interaction of natural and human factors; the former being the topographic, marine traffic volume and meteorological conditions, and the latter being the quality of seafares. In this paper, the authors analyse the trend of marine casualties in the Korean coastal and clear up the cause of accidents and examine closely the mutual relations among sea accidents, weather conditions, and marine traffic volume. These accidents are classified into several patterns on hte point of view of ship's size, ship's type and ship's age and its characteristics of each pattern are described in detail. Also, the authors estimate the amount of economical losses resulting from marine casualties which are classified into the accident patterns, and clarify the effects of those losses on B/B(Balance Sheet) and P/L(Profit & Loss) of Korean shipping companies and Korean national economy. The analyzed results of marine casualties are summarized as follows: 1) The average number of sea accidents is 248 cases per year with the loss of 107 persons during last 13 years. 2) Collision is the top of causes of sea accidents (approx. 36.4%), shipwreck the second (approx. 20.3%), agroung the third rank (approx. 18.2%). 3) The ship's number under 1, 000G/T is approx. 74% of total ship's number of accidents. 4) 80% of total number of marine accidents is taken plact at the coastal waters. (involved ports & narrow channels) 5) Marine casualties are occur likely to in the night, the winter and the summer. 6) The average amount of economical losses is approx. 18.5 billion won. (approx. 0.14% of GNP) 7) Shipwreck is the top of the amount of economical losses (approx. 60.4%), collision the second (aprox. 24.5%), aground the third (approx. 9.9%). 8) The amount of economical losses is approx. 5.24% of gross capital of shipping co., 1.24% of shipping revenue, 1.38% of shipping total income in 1983.

• 대한의료기공학회지
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• 제17권1호
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• pp.24-51
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• 2017

Objective : The purpose of this study is to introduce Whidam's Su-Gi therapy(WST.) as a remarkable traditional manual therapy. Main subject : WST. is a traditional manual therapy from Do-In(導引) An-Kyo(按蹻) that treats disease by controlling Gi(Gi-Gong therapy). It makes treatment effects by pushing Sa-Gi(邪氣) which becomes aggregation-accumulation(積聚) to right places by using pointillage, stroking, and rubbing with doctor's focused intention(意念). The cervical spine connects body and brain, so treating cervical spine could be a foundation of all treatment. Discussion : WST. is a manual therapy that treats not only muscles, nerves, vessels, joints but also Oriental medicine concept-meridian, acupoint and Gi(氣). Conclusions: 1) WST. is a traditional manual therapy using Gi-Gong, 2) WST. changes Sa-Gi(邪氣) into Jung-Gi(正氣), which means curing aggregation-accumulation(積聚), 3) Cervical WST. treats a passage that connects upper and lower parts of human body; heart and brain, and 4) Cervical WST. is a treatment to activate So-Ju-Cheon(小周天), which controls human body immunity.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제30권4호
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• pp.316-322
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• 2004

A low molecular weight component named bone morphogenetic protein(BMP) chemically isolated from the organic matrix of bone, induce postfetal connective tissue cells surrounding small blood vessels to differentiate into cartilage and bone. The end product of BMP is a spherical ossicle of lamella bone filled with red bone marrow for the functional loading. This is a important point that the graft material is embedded the defect site during the implant surgery. Because present knowledge of the relationship between BMP and bone regeneration arises mainly from studies of induced bone formation in heterotopic sites, it would be helpful to determine whether BMP plays any part in the process of bone healing. The BMPs have been shown to play crucial roles in normal skeletal development as well as bone healing and are able to activate transcription of genes involved in cellular migration, proliferation, and differentiation. The delivery of BMP on matrices has been efficacious in the treatment of defect bone in implant surgery. The purpose of the histologic study was to evaluate the effect of DLB(demineralized lyophilized bone) coated with purified human BMP(hBMP-I) in immediate implant surgery with bony defect to obtain the functional structure of implant asap. The ability of a graft of hBMP-I to accelerate bony defect repair provides a rationale for its use in immediate implant surgery that have large bone defect in edentulous area.

• 대한기계학회논문집A
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• 제35권6호
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• pp.619-628
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• 2011

인체의 근육, 힘줄, 피부와 혈관 등은 일상생활 속에서 다양한 손상을 입는 경우가 많으므로 관심을 갖고 연구해야할 주제이다. 인체의 윤상인대의 역학적 특성을 얻기 위해서는 부족한 실험 자료를 감안하고서도 대변형뿐만 아니라 이방성 및 압축성까지 고려해야 하는 어려움이 있다. 본 연구에서는 섬유강화재료 모델을 사용하여 초탄성 재료 모델을 사용하고, 모재, 섬유 및 모재와 섬유와의 상관관계를 포함하는 에너지 함수를 도입하여 실험값과 비교하여 보았다. 윤상인대의 내부에서 2종류의 섬유는 일정한 각도를 갖고 있다고 가정하였다. 섬유강화재료 모델을 사용함에 있어서 모재에 대한 두 종류의 다른 에너지 함수를 대입하여 Neo-Hookean 재료를 사용하여 계산한 결과 및 기존에 알려진 실험결과와 비교하였으며 본 연구에서 제시된 모재에 관한 에너지 함수의 타당성을 보였다.

• 한국발생생물학회지:발생과생식
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• 제21권1호
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• pp.11-18
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• 2017

Potassium channels, the largest group of pore proteins, selectively regulate the flow of potassium ($K^+$) ions across cell membranes. The activity and expression of $K^+$ channels are critical for the maintenance of normal functions in vessels and neurons, and for the regulation of cell differentiation and maturation. However, their role and expression in stem cells have been poorly understood. In this study, we isolated perivascular stem cells (PVCs) from human umbilical cords and investigated the expression patterns of big-conductance $Ca^{2+}$-activated $K^+$ ($BK_{Ca}$) and voltage-dependent $K^+$ ($K_v$) channels using the reverse transcription polymerase chain reaction. We also examined the effect of high glucose (HG, 25 mM) on expression levels of $BK_{Ca}$ and $K_v$ channels in PVCs. $K_{Ca}1.1$, $K_{Ca}{\beta}_3$, $K_v1.3$, $K_v3.2$, and $K_v6.1$ were detected in undifferentiated PVCs. In addition, HG treatment increased the amounts of $BK_{Ca}{\beta}_{3a}$, $BK_{Ca}{\beta}_4$, $K_v1.3$, $K_v1.6$, and $K_v6.1$ transcripts. These results suggested that ion channels may have important functions in the growth and differentiation of PVCs, which could be influenced by HG exposure.

• 센서학회지
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• 제24권4호
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• pp.239-246
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• 2015

Blood pressure is possible to diagnose a disease associated with blood pressure and judgment the current health of patients. Automatic blood pressure monitor capable of measuring a blood pressure easily in hospital and at home have become spread. In this study, we developed the blood pressure simulator (BPS) that can test the arm-type automatic blood pressure monitor that is commonly used in hospital. BPS is to produce a pressure similar to the pressure wave generated in the human blood using a servo disk motor. Then, using the silicon tube, it implements the situations such as human blood vessels, and to output the generated pressure waveform. Simply the BPS's phantom put on the cuff and it is able to simulate blood pressure. So anyone can quickly test the blood pressure monitor within one minute and it is possible to shorten the test time required for the automatic blood pressure monitor. In Performance test, the trends and the standard deviation of the values measured in the BPS is similar to the value of the measured pressure from people with normal blood pressure. Thus, the development BPS showed a possibility of taking into account the actual blood pressure measurement environment simulator.

• 한국콘텐츠학회논문지
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• 제16권7호
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• pp.659-666
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• 2016

현대 사회에서 색채가 인간에게 미치는 영향은 정신적 심리적 측면에서 중요한 요소로 나타나고 있다. 색채는 시지각적으로 인간의 마음에 일어나는 감정과 정서를 연출하여 메마른 감성을 치유하며, 환경은 표현된 색채에 따라 삶의 가치를 높여 주는 역할을 한다. 본 연구에서는 금속의 단조로운 색채표현을 해소하기 위한 측면으로 금속 장신구에 옻칠과 포슬린150물감을 사용하여 표현하는 방법을 응용시켜 다양한 색채변화를 나타내었다. 옻칠과 포슬린150물감의 금속시편을 제작하고 비교 분석하여 장 단점의 결과로 도출하였다. 장점은 이를 접목하는 방법은 금속 색채표현의 일반적인 방법에 비해 색채효과를 다양하게 표현할 수 있었고, 표면 코팅 역할을 하므로 기물의 변색을 방지하여 가변적 문제점을 보완해 줄 수 있었다. 단점은 옻칠은 체질에 따른 옻오름 현상이 나타나고, 포슬린150페인팅은 화학성분으로 식기류에 사용하면 건강에 해로울 수 있다. 이를 참고하여 작품에 적용하여 예술성과 실용성 구현에 기여하고자 한다.