• Title/Summary/Keyword: Human responses

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College Students' Housing Values, Expectations and Considerations for Housing in Their 20s - Centered on Chungbuk Province -

  • Lee, Hyun-Jeong
    • International Journal of Human Ecology
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    • v.14 no.1
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    • pp.71-85
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    • 2013
  • The purpose of this study was to investigate Korean college students' housing values and housing expectations as well as considerations for housing in their 20s and to explore influences on housing values and expectations. Items related to four housing functions were developed in conjunction with Maslow's hierarchy of human needs to measure housing values. An on-site questionnaire survey was administered to students of a university-A located in Chungbuk province between May 28, 2012, and June 17, 2012. Among the total 476 responses, 465 responses from Korean students were used for further data analyses. The findings are as follows: (1) Among housing functions, those related to shelter functions were perceived as most important followed by function as a place for self-esteem. (2) More than 70 percent of the respondents expected to rent a housing unit in their 20s and more than half of the respondents expected non-traditional and relatively affordable compact size structure types such as studio, Officetel or Gosiwon. (3) Price, location and transportation were found to be the most important considerations when choosing housing in their 20s. (4) Convenience in use of public transportation and commute time were found to be the most important in location choice, and maintenance conditions and security systems were the most important for building choice. (5) Female respondents tended to consider personal safety, security systems, neighborhood facilities, and distance from family more important than male respondents when choosing housing, while male respondents considered parking space more important than females.

Overexpression of Protein Kinase $C{\beta}_1$ Restores Mitogenic Responses of Enterocytic Differentiated Colon Carcinoma Cells to Diacylglycerol and Basic FGF

  • Lee, Han-Soo
    • BMB Reports
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    • v.30 no.3
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    • pp.194-199
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    • 1997
  • Previous studies have shown that the HD3 human enterocytic differentiated colon carcinoma cell lines having low $PKC{\beta}$ activity did not respond to diacylglycerol and basic FGF by growth and by activation of pp57 MAP kinase, but undifferentiated cell lines exhibiting high $PKC{\beta}$ activity did. To confirm a role of $PKC{\beta}$ in colonocyte mitogenesis, derivatives of HD3 cell line that stably overexpress a full-length of cDNA encoding the ${\beta}_1$ isoform of human PKC were generated. The abundance and activity of $PKC{\beta}$ in two of the these cell lines, PKC3 and PKC8 were much higher than those in the C1 control cell line that carries the vector lacking the $PKC{\beta}_1\;cDNA$ insert. Following exposure to diacylglycerol or basic FGF, proliferation of PKC3 and PKC8 cells increased about 50%; but this effect was not seen with the control C1 cells. Also, in contrast to the control cells, the $PKC{\beta}_1-overproducing$ cells displayed activation of pp57 MAP kinase when treated with diacylglycerol and basic FGF as undifferentiated cell lines did. These results provide direct evidence that $PKC{\beta}_1$ which plays a key role in mitogenic responses of colon carcinoma cells to diacylglycerol and basic FGF is down-regulated in enterocytic differentiation of colon cells.

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The Inhibitory Effects of Lactose-${\beta}$-sitosterol on the Inflammatory Responses of HMC-1 Cells and EoL-1 Cells

  • Yang, Eun-Ju;Kim, In-Sik
    • Biomedical Science Letters
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    • v.17 no.3
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    • pp.217-223
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    • 2011
  • ${\beta}$-sitosterol glucoside exists in a variety of plants and have anti-tumor, anti-microbial, and immunomodulatory activities. Mast cells and eosinophils play important roles in a variety of inflammatory diseases, specifically asthma and atopic dermatitis. In the present study, we used lactose-${\beta}$-sitosterol (L-BS) and investigated the effect of L-BS on inflammatory responses of the human mast cell line, HMC-1 and the human eosinophilic leukemia cell line, EoL-1. In HMC-1 cells, L-BS significantly inhibited cell migration in response to stem cell factor without cytotoxicity. However, the mRNA expression of CC chemokine receptors (CCRs), including CCR1-5, were not altered after L-BS treatment in HMC-1 cells. LPS-induced IL-4 production was also suppressed by L-BS in a dose-dependent manner. In EoL-1 cells, the concentration ranging from 0.1 ${\mu}M$ to 10 ${\mu}M$ of L-BS had no cytotoxicity and had no effect on mRNA expression of major protein-mediators derived from activated eosinophils. However, 100 ${\mu}M$ of L-BS induced the apoptosis of EoL-1 cells in a time-dependent manner. This finding indicates the possibility of L-BS as a potential therapeutic molecule in inflammatory diseases and may contribute to the need to improve current therapeutic drugs.

The Analysis of Wearers' Impression to Combination of their Body Type with Neutral Tone Wear - focused on Pants- (체형과 무채색 톤조합에 따른 의복 착용자의 인상 평가 -팬츠차림을 중심으로-)

  • Paeng, Suk-Kyung;Kang, Kyung-Ja
    • Korean Journal of Human Ecology
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    • v.15 no.4
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    • pp.631-646
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    • 2006
  • The purpose of this study is to find out its effect on wearers' impression formated by combination of their body type with neutral tone clothing. The experimental materials developed for this study are a set of responses to stimulus in scales(7-point semantic). 45 pictures used as stimulus are, through computer simulation, manipulated to five wearers' body type and nine neutral tone wear. The subjects are 276(?) female undergraduate students in Kyung-nam area. Factors on wearers' impression suggested as responses to the stimulus consist of 5 different demensions (Tenderness, Cuteness, Attractiveness, Elegance, Intrepidity). The results of this study are as follows: first, combination of their body type with neutral tone wear significantly affects the formation of wearers' impression in the factor of Tenderness, Attractiveness, and Intrepidity (?); to the factor of Attractiveness, wearers' body type is rather more related than wearers' neutral tone wear is. Second, the harmony of their body type with neutral tone wear has a significant effect on wearers' impression in the factor of Cuteness. According to those results, the combination of wearers' body type with neutral tone wear has significant effects on the formation of wearers' impression.

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Enhancement of Mucosal Immune Functions by Dietary Spirulina platensis in Human and Animals

  • Osamu Hayashi;Kyoko Ishii;Chinami Kawamura;Hei, Shi-Yen;Bao, Ning-Ye;Tomohiro Hirahashi;Toshimitsu Katoh
    • Nutritional Sciences
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    • v.7 no.1
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    • pp.31-34
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    • 2004
  • This paper reviews the effects of Spirulina platensis and its extracts and phycocyanin, a blue photosynthetic pigment protein in Spirulina on the mucosal immune functions in humans and animals as follows: TEX>$\bullet$ IgA antibody response and other classes in mucosal immunity of mice treated with Spirulina platensis and its extract. $\bullet$ Effect of Spirulina phycocyanin ingestion on the mucosal antibody responses in mice. - Distinct effects of phycocyanin on secretory IgA and allergic IgE antibody responses in mice following oral immunization with antigen-entrapped biodegradable microparticles. $\bullet$ Influence of dietary Spirulina platensis on IgA level in human saliva. $\bullet$ A study on enhancement of bone-marrow cell-proliferation and differentiation by Spirulina platensis in mice: in vivo and in vitro study

The Threat of AI and Our Response: The AI Charter of Ethics in South Korea

  • Hwang, Ha;Park, Min-Hye
    • Asian Journal of Innovation and Policy
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    • v.9 no.1
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    • pp.56-78
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    • 2020
  • Changes in our lives due to Artificial Intelligence (AI) are currently ongoing, and there is little refutation of the effectiveness of AI. However, there have been active discussions to minimize the side effects of AI and use it responsibly, and publishing the AI Charter of Ethics (AICE) is one result of it. This study examines how our society is responding to threats from AI that may emerge in the future by examining various AIECs in the Republic of Korea. First, we summarize seven AI threats and classify these into three categories: AI's value judgment, malicious use of AI, and human alienation. Second, from Korea's seven AICEs, we draw fourteen topics based on three categories: protection of social values, AI control, and fostering digital citizenship. Finally, we review them based on the seven AI threats to evaluate any gaps between the threats and our responses. The analysis indicates that Korea has not yet been able to properly respond to the threat of AI's usurpation of human occupations (jobs). In addition, although Korea's AICEs present appropriate responses to lethal AI weapons, these provisions will be difficult to realize because the competition for AI weapons among military powers is intensifying.

Layering Effects on Clothing Microclimate, Clothing Insulation and Physiological Responses

  • Park, Joonhee;Yoo, Shinjung
    • International Journal of Human Ecology
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    • v.14 no.2
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    • pp.93-103
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    • 2013
  • This study investigated the relationship of clothing microclimate and physiological responses in order to examine the layering effects on the clothing microclimate as an index to predict clothing thermal insulation ($I_{cl}$). Experiments were conducted in a $15^{\circ}C$ environment on six physically active males. Increased clothing layers resulted in higher mean temperature inside the clothing ($\bar{T}_{cl}$) and $I_{cl}$. The $I_{cl}$ had a high correlation with: $\bar{T}_{cl}$ (r = 0.556), the difference between the innermost surface temperature and the outermost surface temperature at the chest (DST) (r = 0.549) and the temperature inside clothing at the abdomen (r = 0.478). $\bar{T}_{cl}$ had the highest correlation with the temperature inside clothing at the abdomen (r = 0.889). $\bar{T}_{cl}$ also had the highest correlation with $\bar{T}_{sk}$ (r = 0.860). The results showed that the relationship between $I_{cl}$ and $\bar{T}_{cl}$ was linear (p < .01). Thermal comfort had a negative correlation with $\bar{T}_{cl-thigh}$ (r=-0.411) and $\bar{T}_{cl}$ (r = -0.323) (p < .01.)

The Combined Environmental Factors on the Human Physiological and Psychological Responses in Indoor Space (실내공간의 복합 환경 조건이 인체의 생리 및 심리반응에 미치는 영향)

  • Yoon, In
    • Journal of the Korean Society of Industry Convergence
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    • v.15 no.3
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    • pp.87-94
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    • 2012
  • Kruithof demonstrated the preferred combination of illuminance levels and color temperatures. However, as Benett pointed out, difference of themal variables in such preference may be expected. The purpose of this study is to clarify the combined effects of lighting conditions(illuminance, color temperature), operative temperature on the human physiological and psychological responses. In order to observe operative temperature change in preference of color temperatures for three illumination levels, three subjects were exposed to two different conditions of color temperatures of 2,850K, 4,200K and 6,850K combined with operative temperatures(OT) of $25{\sim}31^{\circ}C$ at 100~1000lx. Thermal sensation vote and comfortable sensation vote, brightness perception vote were reported in each experiment conditions. The following results were obtained : 1) When illuminace level was at 100lx in operative temperatures of OT $20^{\circ}C$, $25^{\circ}C$, $30^{\circ}C$, Color temperature affect not themal sensation but Warm-cool sensation. 2) Operative temperatures affect not brightness perception vote but visual comfort sensation vote, satisfactive sensation vote, warm-cool sensation vote and themal sensation vote.

Human Response Measurement and Ride Quality Evaluation for Seats having various Material Porperties (물성치가 다른 시트에서의 인체 진동 측정 및 승차감 평가)

  • 조영건;박세진;윤용산
    • Transactions of the Korean Society of Automotive Engineers
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    • v.8 no.3
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    • pp.171-180
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    • 2000
  • This paper deals with the whole-body vibration and ride quality evaluation in the vertical direction. The responses of the floor, hip, back, and head in four subjects were measured for various seats when the floor was excited by random vibration with r.m.s of 1.2m/s2 in the vertical direction. In the transmissibility between the hip and floor, the fundamental mode is observed at 4.4 Hz. In the transmissibility between the head and floor, the fundamental mode at 4.4Hz and the second mode at 7.6Hz are observed. It is shown that the head motion is 41% larger than the hip motion and the response of female subject is larger than that of male subject. The response without backrest also was compared with that with backrest. From these human responses ride quality of five seats were evaluated by the ride value such as transfer ration having frequency weighting function is the statistical sense. It is observed that the seat having high damping property can reduce the most acceleration exposed to hip in the statistical sense for all ride valves, while the seat having different seat spring doesn't show statistical difference.

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Comparison and Analysis of Response of Premature Infants to Auditory Stimulus (일변량 분산 분석과 이변량 시계열 분석을 이용한 미숙아의 목소리 자극에 대한 심박동수와 호흡수 반응의 비교)

  • Lee, Hye-Jung
    • Child Health Nursing Research
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    • v.15 no.3
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    • pp.261-270
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    • 2009
  • Purpose: The purpose of this study was to compare the result of one-way ANOVA with that of cross-correlation time series analysis in order to evaluate physiologic responses of premature infants to human voices. Methods: Four premature infants born prior to 32 weeks gestational age were included in the study. The Gould 4000TA Recording System recorded the preterm infant's heart and respiratory rate while they were listening to a pre-recorded voice recording. Each infant listened to both male and female voices (1 min each) at each testing session. Results: The results of both one-wayANOVA and cross-correlation time series analysis using heart and respiratory rate data were not consistent in some of premature infants. A cross-correlation time series analysis revealed that the responses of premature infant to vocal stimulation occurred at a varying number of seconds after the stimulus was presented and lasted for over 20-30 sec. Conclusion: The results indicate that a time series analysis can provide more detailed information on the rapidly changing physiologic status of premature infant to the auditory stimulus. In addition, the results provide an insight into an auditory responsitivity of premature infants to a naturally occurring sound, the human voice, in the neonatal intensive care unit.

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