Enhancement of Mucosal Immune Functions by Dietary Spirulina platensis in Human and Animals

  • Osamu Hayashi (Department of Health and Nutrition, Kagawa Nutrition University) ;
  • Kyoko Ishii (Department of Health and Nutrition, Kagawa Nutrition University) ;
  • Chinami Kawamura (Department of Health and Nutrition, Kagawa Nutrition University) ;
  • Hei, Shi-Yen (Department of Health and Nutrition, Kagawa Nutrition University) ;
  • Bao, Ning-Ye (Department of Health and Nutrition, Kagawa Nutrition University) ;
  • Tomohiro Hirahashi (Biochemical Division, Kainippon Ink & Chemicals Inc.) ;
  • Toshimitsu Katoh (Biochemical Division, Kainippon Ink & Chemicals Inc.)
  • Published : 2004.02.01

Abstract

This paper reviews the effects of Spirulina platensis and its extracts and phycocyanin, a blue photosynthetic pigment protein in Spirulina on the mucosal immune functions in humans and animals as follows: TEX>$\bullet$ IgA antibody response and other classes in mucosal immunity of mice treated with Spirulina platensis and its extract. $\bullet$ Effect of Spirulina phycocyanin ingestion on the mucosal antibody responses in mice. - Distinct effects of phycocyanin on secretory IgA and allergic IgE antibody responses in mice following oral immunization with antigen-entrapped biodegradable microparticles. $\bullet$ Influence of dietary Spirulina platensis on IgA level in human saliva. $\bullet$ A study on enhancement of bone-marrow cell-proliferation and differentiation by Spirulina platensis in mice: in vivo and in vitro study

Keywords