• 제목/요약/키워드: Human research subjects

검색결과 1,295건 처리시간 0.042초

적조연구프로젝트 관리모형에 관한 연구 (HABs Research Project Management Model)

  • 어윤양;김창완;이현규
    • 수산경영론집
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    • 제34권2호
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    • pp.165-183
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    • 2003
  • The effect of red tide on the marine ecological system is so severe that many researches on the diverse subjects related to it have been conducted. Notwithstanding the enormous efforts and inputs the results of the past researches show no clear ways to deal with the HAB problems. As many researches are being conducted, the efficient and appropriate research project management systems as one of the critical factors for successful research are also needed as well as the fund and the capabilities of the researchers. It is assumed that the development of the evaluation and management systems for red tide research projects is so important and critical to enhance the researches and to utilize efficiently the physical and human resources for research. In this respect this study aims to present the evaluation and management scheme for the red tide researches that can not only decide the priority of the research subjects and tell the desirable research directions, but also support to develop the useful managerial policies and guidelines for the policy maker. The main subjects dealt with in this study are as follows : the characteristics of the HAB researches, the basic attributes and criterion of the research evaluation systems, the structure and design of the evaluation systems, and the development of the managerial policies by the type of the evaluation system. The conceptual scheme developed in this study is expected to be applied to the related areas and can suggest to the policy makers so many implications for identifying and setting the proper policy objects and management techniques. This study has a couple of weak points. It suggests only the conceptual scheme but not the applications so that the researches focusing on the applications in practical perspectives are needed to follow.

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Batch Variation and Pharmacokinetics of Oral Sustained Release Melatonin-loaded Sugar Spheres in Human Subjects

  • Lee, Beom-Jin;Ryu, Seung-Goo;Choi, Han-Gon;Kim, Chong-Kook;Parrott, Keith-A.;Ayres, James-W.;Sack, Robert-L.
    • Archives of Pharmacal Research
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    • 제20권6호
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    • pp.555-559
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    • 1997
  • The three different batches of an oral sustained release melatonin (MT) delivery system were prepared by aqueous-based fluid-bed coating of the sugar spheres for the evaluation of in vitro release characteristics and plasma concentration profiles in human subjects. The MT contents in 20% coated sugar spheres of three batches (B1, B2 and B3) were $3.3{\pm}0.08$, $2.4{\pm}0.1$ and $2.5{\pm}0.13$ mg per gram of coated sugar spheres, respectively. The release profiles of three different batches had a very similar fashion. However, the release profiles of three different batches had a very similar fashion. However, the release half-lives $(T_{50%})$ of MT from B1, B2 and B3 was $3.70{\pm}0.2$, $5.2{\pm}0.2$ and $4.9{\pm}0.07h$, respectively. Plasma concentration profiles of sustained release 0.2mg melatonin-loaded sugar spheres containing 10% immediate release melatonin in gelatin capsules (B1 and B2) were then evaluated in human subjects. The in vivo plasma concentration profies of the two batches (B1 and B2) were very similar each other and located between the physiological endogenous ranges. The time to reach the peak concentration $(T_max)$ was more advanced in case of B1 when compared to B2. However, there was no statistically significant difference in the maximum concentration $(C_max)$ and the area under the curve (AUC) between B1 and B2. The AUC of melatonin-loaded sugar spheres containing 10% and 20% immediate release MT in human subjects had a good linearity between dose and AUC, regardless of the fraction of immediate release MT, indicating the first order elimination process of MT within these doses. The current oral sustained release MT delivery system may be utilized to treat circadian rhythm disorders if it is proven to be more clinically useful when compared to immediate release MT.

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대구지역 동계 제복 근무자의 피복 착의 앙상블과 쾌적성의 주관적 평가 (The Subjective Estimation on the Ensemble and Comfort of Workers Wearing winter Uniform in Taegu)

  • 류덕환;이옥자;김승진;송민규;조지현;정명선
    • 한국의류산업학회지
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    • 제2권3호
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    • pp.253-264
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    • 2000
  • The purpose of this study was to examine the thermal comfort characteristics of the garments for school, textile and bank worker's uniform. The garments selected for this study were frequently used in Taegu area in terms of design and material used for making garments by the survey for the study The human subject tests were performed to determine the thermal comfort characteristics of garments including thermal, humidity, and wearing sensation and the data were analysed statistically. The results of the study were as follows: 1. According to the result of the survey jacket was mostly used as a school uniform for both male and female high school students. The survey showed that 93% of male students wore 'neck T-shirts' and dimensional fitness for the school uniform got suitable at 2~3 grade high school students. In terms of human subject tests, most students rated 'uncomfortable' in wearing sensation of their school uniform. One of this reason was due to the humidity sensation and air velocity sensation. Level of significance of the thermal sensation for gender difference was higher in hands and feet of the subjects than in chest and thigh of them. 2. According to the result of the survey jacket with zipper was mostly used as a textile worker's uniform. The result of the survey indicated that some textile workers are wearing their inner wear (38.7% for upper and 46.6% for lower). In the human subject tests, about 50% of subjects rated 'comfortable to slightly comfortable' for wearing sensation of the textile worker's uniform. It showed that the female subjects of the humidity sensation was rated higher than the male subjects of the humidity sensation, while the male subjects of the thermal sensation was rated higher than the female subjects of the thermal sensation. There was a closer correlation with the subjective thermal sensation for textile worker's uniform in center parts of the subjects such as back and waist than exposed parts. 3. The result of the survey showed that 70% and 23% of the female banker uniform were blouse and jacket, respectively and 75% and 25% of the male banker uniform were jacket and T-shirt, respectively. All interviewee rated trousers and skirts that were used for their lower. 4. The result indicated that 50% male and 67.7% female subjects for the banker uniform rated 'slightly comfortable for the comfort' sensation. 50% male subjects rated 'neutral' and about 50% female subjects rated 'slightly warm to neutral' for the thermal sensation. In addition, The result showed that 75% male subjects for both upper and lower rated 'neutral' for the humidity sensation and also 75% female subjects rated 'neutral to slightly dry'. Thus, there was no significant different between gender. 5. In the thermal sensation of the subjects for the banker's uniform by parts, 50% subjects rated 'neutral' for their body parts, including head, neck, back, waist, hip, lower arm, and thigh. The extremely cold parts were hands and feet for both male and female subjects.

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웨딩드레스용 프린세스라인 원형개발 연구 - 25~34세 표준체형 여성을 위한 드레이핑 기법으로 - (A study princess line patterns for wedding dresses - Draping technique for standard body type women from age 25 to 34 -)

  • 김해연;박선경;정재철
    • 복식문화연구
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    • 제25권6호
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    • pp.913-927
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    • 2017
  • This study is based on the results of the $7^{th}$ Korea Human Size Survey (Size Korea). The standard body shapes of Korean women between 25 and 34 years old were analyzed and used to develop a prototype princess line for wedding dresses. or this purpose I conducted a literature review and a survey of the actual situation of domestic ligaments. In order to select suitable ligaments for the standard body type of 25~34 year-old Korean women, I collected the most representative ligaments from around the world: Stock man from France, Superior from the USA, KIIYA from Japan, and Pig and Nonno from Korea. They were then compared and analyzed. In the form of a formal wedding dress, a prototype princess line was developed by a draping technique in order to finely implement the human body fitting. To develop the prototype of the princess line, I made test garments with muslin. 25 to 34 years old Korean female standard body type Three human subjects close to the average measurement value were selected as subjects. An exterior appearance evaluation questionnaire was created with 28 questions focusing on the main parts of the prototype princess line. The clothes were evaluated three times. In this study, aesthetic and functional elements were considered for the development of princess line prototypes for wedding dresses. In addition, the amount of spare area was given differently. This study is significant in the achievement of a dress line closest that closely matches the human body line of the standard Korean female body type.

콩을 주제로 한 프로젝트 접근법이 유아의 과학적 탐구 능력과 과학적 태도에 미치는 영향 (The Impact of the Project Approach Utilizing Beans As the Subject Matter on Young Children's Scientific Research Capabilities and Scientific Attitudes)

  • 조미정;안진경
    • 한국생활과학회지
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    • 제18권3호
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    • pp.631-639
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    • 2009
  • This study examines how the project approach utilizing beans as the subject matter influences young children's scientific research capabilities and scientific attitudes. This examination ultimately aims at developing effective teaching methods and programs that can promote children's scientific research capabilities and scientific attitudes. Thirty six children at H kindergarten in Gunsan, Jeollabuk-do were selected as subjects of this study. The children aged five were divided into an experiment group and a comparison group, with eighteen for each group. Before the experiment, a pre-test was conducted on the children's scientific research capabilities and scientific attitudes. The pre-test results were subject to a t test to identify whether there were differences between the two groups in age as well as the levels of scientific research capabilities and attitudes. A post-test was also conducted to determine the differences between the two groups in these categories. These results have led to the conclusion that the project approach utilizing beans as the subject matter has a positive impact on improving young children's scientific research capabilities and scientific attitudes.

가족 레질리언스에 대한 선행연구 고찰: 현황과 과제 (Review and Prospects for Research on Family Resilience)

  • 박혜란;전귀연
    • 한국생활과학회지
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    • 제21권6호
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    • pp.1059-1082
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    • 2012
  • The purpose of this study was to analyze the trends, research methodology and findings of various researches on family resilience published in Korea over the past 13 years. A total of 93 publications related to family resilience between 1999 and June of 2012 were analyzed; 72 journal articles and 21 doctoral dissertations which had not been published in academic journals. The results are as follows; (1) There has been steady increase in the number of related researches since 1999, with a significant increase since the mid-2000s as various nontraditional families emerged and the perception of family problems began to change. (2) With regards to the methodology, the majority of the studies were empirical, using quantitative methods in both data collection and analysis. Most measurement scales employed were based on inventories developed by foreign researchers. (3) The research subjects encompass a wide range of individuals and groups from both vulnerable families and families from the general population. Additionally, some researches focused on special interest areas including program development & evaluation and scale development. Although research on family resilience has increased in quantity, there needs to be more qualitative, longitudinal and theory grounded studies on different families and individual types to better understand family resilience in depth. In addition, specific measurement scales reflecting the unique Korean family culture should be developed. Other challenges and suggestions for future research on family resilience are discussed.

Effects of a Pre-Exercise Meal on Plasma Growth Hormone Response and Fat Oxidation during Walking

  • Shin, Young-Ho;Jung, Hyun-Lyung;Ryu, Jong-Woo;Kim, Pan-Soo;Ha, Tae-Yeol;An, Ji-Yoon;Kang, Ho-Youl
    • Preventive Nutrition and Food Science
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    • 제18권3호
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    • pp.175-180
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    • 2013
  • The purpose of this study was to determine the effects of a pre-exercise meal on the plasma human growth hormone (hGH) response and fat oxidation during walking. Subjects (n=8) were randomly provided with either 1 g/kg body weight of glucose in 200 mL water (CHO) or 200 mL water alone (CON) 30 min prior to exercise and subsequently walked on a treadmill at 50% of VO2max for 60 min. Plasma hGH concentrations were significantly higher in subjects who received CHO compared to those who received CON at 15 and 30 min. The fat oxidation rate in the CHO was significantly lower than the CON while walking for 5~15, 25~35 and 45~55 min. Plasma FFA levels were also significantly lower in the CHO compared to the CON at 30, 45 and 60 min. Plasma glucose levels in the CHO were significantly lower while plasma insulin levels were significantly higher than in the CON at 15 and 30 min. Therefore, the results of this study suggest that the elevation of plasma hGH levels due to the intake of a pre-exercise meal may not be strongly related to fat oxidation and plasma free fatty acid (FFA) levels during low-intensity exercise.

토털 이미지에 관한 연구 - 매너를 중심으로 - (A Study on Total Image - Focus on Manner -)

  • 황진희;이해영
    • 한국생활과학회지
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    • 제12권3호
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    • pp.391-402
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    • 2003
  • Total image consists of body analysis, fashion coordination, and manners. This stydt will be utilized to develop a clinic program using the concept of total image, with a focus on manners, which is important in the modem age. The manners was examined m the following categories; the importance of manners, level of manners, he order of manners sents felt important, and contents of manners the subjects deemed necessary. The research was conducted using 400 male and female college students living In the Daejeon area. The data were processed statistically using the SPSS package, and administered the frequency and percentages, andthe $x^2-test$. Results are as follows. Both male and female students acknowledged manners as a significant factor in forming the total image, and they possessed a medium level of manners. College students felt the importance of manners in the following order: everyday life manners, facing manners, telephone manners, and fashion coordination manners. There was a difference between male and female students in the contents of manners. Whereas manners the subjects deemed necessary for male students were facing manners(name use, introduction, handshaking, card exchange), everyday life manners(drinking, moking), those for female students were telephone manners, facing manners(greeting, expression), everyday life manners(individual life, eating, visiting), fashion coordination manners(special occasions, interviews. invitations, MT).

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중년기 비만여성을 위한 기존 재킷의 패턴분석 (The Analysis of Manufactured Jacket Pattern for Obese Women in Their Middle Age)

  • 손부현;홍경희;박세진
    • 한국생활과학회지
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    • 제14권3호
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    • pp.475-483
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    • 2005
  • The ready-made clothes for obese women are not manufactured systematically due to the diversity and scarcity of their body shape. In this study, we first analyzed and classified 104 obese women's body shape to select four representative subjects. Then, the four subjects participated in wearing test to evaluate the performance of the jacket patterns which are available in the market and widely-used at the same time. The characteristics of the jacket patterns for obese women were also investigated. As to the highly rated jacket in terms of body motion, it was found that difference between the breast width to axilla and the breadth to anterior midaxilla is larger than the other jackets, and the breast width of front body is wider than what of back width. It was noted, however, that the armhole depth and the width of obese women' jackets should not be determined indirectly by the magnitude of the girth around bust, waist or hip as in the case of regular sized women's. It is because body proportion of obese women is different from that of standard sized women.

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초등학생의 학교적응에 대한 자아탄력성과 사회적 지지의 상호작용효과 (Effects from the Interaction of Ego-Resilience, Social Supports in the School Adjustment of Elementary School Children)

  • 송영경;김영희;황성실
    • 한국생활과학회지
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    • 제20권1호
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    • pp.1-19
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    • 2011
  • The purpose of this study was to investigate the interactions of ego-resilience and social supports in the school adjustment in children. The subjects of this study were 479 children drawn from the fourth and sixth grades of three elementary schools in Cheongju city. The pilot study was done to examine the applicability of survey instruments. Data was analyzed by frequency, percentage, Cronbach's t-test, ANOVA with Tukey post-hoc test, correlation, and hierarchial analysis using the SPSSWIN program. The results of this research were as follows: First, the results showed that the effects of the interaction of ego-resilience and social supports on school adjustment were different according to the children's gender and age. Second, teacher supports had influence on school life satisfaction, interest in the subject, attitude in class, and observance of school rules according to the children's gender and age. Finally, overall, the influence of school life satisfaction, interest in subjects, attitude in class, and observance of school rules was greater for girls than boys.