• 한국방사선학회논문지
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• 제15권3호
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• pp.307-312
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• 2021

핵의학에서 Dose calibrator는 단일 핵종의 방사능을 측정하기 위해 사용하는 장비이다. 인체에 정확한 용량의 투여는 진단과 치료에 중요한 요인으로 작용하며, 투여 전 Dose calibrator를 통한 방사능 측정은 가장 중요한 요소이다. 이러한 Dose calibrator는 각 의료기관에서 설치 후 일상적인 정도 관리를 시행한다. 정도관리는 설치 후 품질관리를 보증하는 하나의 방편이며 진료의 질을 향상시키고 환자의 안전을 도모하는 데 필수적이다. 이에 정확하고 표준화된 성능 평가 방법을 구축해야 한다. 따라서 본 연구는 정도관리의 정확도와 기준성을 높여 품질 관리의 정량적 평가를 위해 3D 프린트를 이용하였다. 연구 방법은 정도관리를 위한 Q.C 표준선원이 중앙에 장착될 수 있는 3D 프린트를 이용한 보조기구를 재작하였다. 재현성 검사를 시행하였을 때 3D 프린트의 장착 유무에 따른 정도관리 선원의 오차율 값의 차이를 비교하였다. 연구 결과 표준선원의 정도관리 기댓값과 판독값의 오차 범위가 F-18 핵종에서는 0.302% 감소하였고, ^99mTc-pertechneate 핵종에서는 0.09% 로 나타났다. 향후 정량적이고 표준화된 정도관리를 통해 장비의 노후화, 표준선원의 반감기에 따른 계산 오류 등 정도관리의 영향을 주는 요인을 감소시키고 정확한 방사성의약품을 투여할 수 있는 기본적인 요인으로 작용할 수 있을 것이라 사료된다.

• 한국의류학회지
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• 제30권1호
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• pp.157-166
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• 2006

The human body, which is composed of concave and convex curvatures, makes it difficult to transfer into 2D patterns directly from 3D data. In previous studies. Jeong, et al.(2004) suggested the block method was fester and easier when dealing with the triangular patches of male's upper dress form. Although the block method is useful to make a pattern, the information(area, length, etc.) from a 2D pattern would be different depending on the direction of the block method. As a result horizontal and diagonal block methods were suggested as optimal methods for 2D tight-fitting patterns. These block methods were closer to the original area of the 3D scan data than the vertical block method. The total area of the 2D pattern obtained by the horizontal and diagonal block methods showed little differences. In case of the horizontal and diagonal block methods, the total error of the 2D pattern area ranged from $0.01\%\~0.25\%$. In comparing the length of the 2D pattern with that of the 3D scan data, the obtained 2D pattern was $0.1\~0.2cm$ shorter than the 3D scan data, which was within the acceptable range of errors in making clothes. 3D space distribution images between the body surface and the experimental clothing were also measured and $3\%$ enlargement of the original pattern was verified as the adequate adjustment.

• 대한인간공학회지
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• 제16권3호
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• pp.1-10
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• 1997

This paper is concerned with the development and evaluation of the camera calibration method for a real-time head tracking system. Tracking of head movements is important in the design of an eye-controlled human/computer interface and the area of virtual environment. We proposed a video-based head tracking system. A camera was mounted on the subject's head and it took the front view containing eight 3-dimensional reference points(passive retr0-reflecting markers) fixed at the known position(computer monitor). The reference points were captured by image processing board. These points were used to calculate the position (3-dimensional) and orientation of the camera. A suitable camera calibration method for providing accurate extrinsic camera parameters was proposed. The method has three steps. In the first step, the image center was calibrated using the method of varying focal length. In the second step, the focal length and the scale factor were calibrated from the Direct Linear Transformation (DLT) matrix obtained from the known position and orientation of the camera. In the third step, the position and orientation of the camera was calculated from the DLT matrix, using the calibrated intrinsic camera parameters. Experimental results showed that the average error of camera positions (3- dimensional) is about $0.53^{\circ}C$, the angular errors of camera orientations are less than $0.55^{\circ}C$and the data aquisition rate is about 10Hz. The results of this study can be applied to the tracking of head movements related to the eye-controlled human/computer interface and the virtual environment.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제33권4호
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• pp.307-311
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• 2007

Purpose: The aim of this study was simply assessing linear measurements in the lateral and medial approach, respectively, for bone harvesting using anatomic and three-dimensional(3D) computed tomographic(CT) analyses on a dried cadaveric proximal tibia. In addition, the availability of the three-dimensional computed tomographic(3D-CT) analysis was also estimated. Materials and methods: Ten dried proximal tibia were obtained from five Korean cadavers. Four the reference points, the SM(superior-medial), IM(inferior-medial), SL(superior-lateral), and IL(inferior-lateral) were marked around the tibial tuberosity. The PM(posterior-medial) and PL(posterior-lateral) points were randomly marked at points farthest from the lateral and medial reference points, respectively, in the posterior border of the superior articular surface of both condyles. All measurements were obtained on the dried proximal tibia. After computed tomography had been performed, the three dimensional images were reconstructed using V works $4.0^{TM}$(Cybermed Inc., Seoul, Korea), and the length between the reference points were measured three dimensionally using the method described above. The error between the mean actual and mean 3D-CT measurements was calculated in order to determine the availability of the three dimensional computed tomographic analysis. Results: The length between the reference points was greatest at the IL-PM, which averaged $65.39mm{\pm}10.35$. This was followed by the SL-PM with $63.24mm{\pm}8.10$, the IM-PL with $58.09mm{\pm}10.02$, and the SM-PL with $51.99mm{\pm}9.06$. The differences between the IL-PM and SM-PL were 13.4 mm. The mean values were 55.04 mm in the medial approach and 64.32 mm in the lateral approach, and the differences between medial and lateral were 9.28 mm. The error between the mean actual and mean 3D-CT measurements was 0.31% and the standard deviation was 0.28%. Conclusion: The anatomical and three dimensional computed tomographic analysis indicates that there was only a 9.28 mm linear difference between the lateral and medial approach. This is consistent with previous studies, which showed that there was little difference between the two approaches in terms of the bone volume. In addition, the error(0.31%) and the standard deviation(0.28%) were considered low, demonstrating high accuracy of 3D-CT. Therefore it can be used in preoperative treatment planning.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제5권8호
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• pp.393-400
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• 2016

최근, 컴퓨터 비전과 기계 학습 기술의 도움을 받아 효율적이고 자동적인 도시 환경에 대한 분석 방법의 개발에 대한 연구가 이루어지고 있다. 많은 분석들 중에서도 도시의 안전도 분석은 지역 사회의 많은 관심을 받고 있다. 더욱 정확한 안전도 점수 예측과 인간의 시각적 인지를 반영하기 위해서, 인간의 시각적 인지에서 가장 중요한 전역 정보와 지역 정보의 고려가 필요하다. 이를 위해 우리는 전역 칼럼과 지역 칼럼으로 구성된 Double-column Convolutional Neural Network를 사용한다. 전역 칼럼과 지역 칼럼 각각은 입력은 크기가 변환된 원 영상과 원 영상에서 무작위로 크로핑을 사용한다. 또한, 학습 과정에서 특정 칼럼에 오버피팅되는 문제를 해결하기 위한 새로운 학습방법을 제안한다. 우리의 DCNN 모델의 성능 비교를 위해 2개의 SVR 모델과 3개의 CNN 모델의 평균 제곱근 오차와 상관관계 분석을 측정하였다. 성능 비교 실험 결과 우리의 모델이 0.7432의 평균 제곱근 오차와 0.853/0.840 피어슨/스피어맨 상관 계수로 가장 좋은 성능을 보여주었다.

• 대한인간공학회지
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• 제16권3호
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• pp.71-75
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• 1997

This paper presents the development of videobased 3-dimensional tracking system. Measurement of human motion is important in the application of ertonomics. The system uses advanced direct video measurement technology. Passive retro-reflecting markers are attached to a subject and movements of markers are observed by two CCD cameras. Infrared light emitted near the CCD cameras is reflected by the markers and is detected by the cameras. The images are captured by Samsung MVB302 board and the centers of markers are calculated by DSP program. The positions of markers are transferred from MVB02 board to the computer through AT bus. The computer then tracks the position of each marker and saves the data. This system has dynamic accuracy with 0.7% average error and 4.2% maximum error, and the sampling rate to 6 .approx. 10 Hz, and this system can analyse the trajectory and speed of the marker. The results of this study can be used for operator's motion analysis, task analysis, and hand movement characteristic analysis.

• Bulletin of the Korean Chemical Society
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• 제32권3호
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• pp.977-980
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• 2011

A new analytical method for measurement of 3,4-dihydroxyphenylalanine (DOPA) in human urine was developed. DOPA from an aqueous solution was converted into an ethoxycarbonyl (EOC) derivative. A tertbutyldimethylsilyl (TBDMS) reaction under anhydrous conditions was then attempted for analysis by gas chromatography-mass spectrometry in selected ion monitoring mode. A new mass spectral data on DOPA as a tri-EOC/mono-TBDMS derivative was built. This method showed good linearity (r ${\geq}$ 0.999), precision (% relative standard deviation = 3.1-9.2), and accuracy (% relative error = -7.2-8.8), with a detection limit of 0.05 ng/mL. This selective and accurate method of DOPA analysis will be useful for biochemical monitoring of various neurological disorders including Parkinson's disease in biological fluids.

• 한국의학물리학회지:의학물리
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• 제22권1호
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• pp.35-41
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• 2011

전반적 시스템 점검(overall system test)을 위해 일반적으로 필름을 이용한 hidden-target test가 시행되어 왔으나 2차원적 측정기로 3차원적인 방사선 영역(radiation field)을 구(sphere)라 가정하고 목표 중심점을 찾는 것이 내재적 분석 오차를 야기시킨다. 본 연구에서는 겔 선량계를 이용하여 3차원적 목표 중심점 오차를 확인하고 이 기술을 소개하고자 한다. 실제 환자의 두경부를 모사할 수 있으며 10개의 겔 선량계를 내부에 삽입할 수 있는 팬텀을 제작하였고 원하는 시기에 합성과 자유로운 용기 선택이 가능한 $BANGkit^{TM}$을 겔 측정기로서 사용하였다. 필름을 이용하는 분석방법이 야기시키는 내재적 분석 오차를 정량적으로 확인 하기 위하여 2개의 방사선 영역은 타원(ellipse) 나머지 8개는 구 형태로 설정하였다. 방사선 수술 전용 선형가속기 기반의 치료기인 노발리스를 이용하여 모의 치료를 3번 반복 수행하였고 $BrainSCAN^{TM}$의 Image fusion, Drawing, Windowing setting 등의 내장 기능을 이용하여 자기공명영상 상의 방사선 영역을 추출하고 기하학적 중심 점을 측정하였다. 본 연구의 목표 중심점 분석 결과는 10개의 방사선 영역에 대해 $0.77{\pm}0.15mm$의 목표 중심점 오차가 발생하였고 각 AP (anterior-posterior), LAT (lateral), VERT (vertical) 방향으로 $0.54{\pm}0.23mm$, $0.37{\pm}0.08mm$, $0.33{\pm}0.10mm$의 방향별 목표 중심점 오차를 갖는다. 10개의 방사선영역 모두에서 목표 중심점 오차는 1 mm 이내이므로 방사선 수술을 시행하기에 적합한 치료 절차와 치료 장비를 갖추고 있음을 간접적으로 보여주었고 자기공명영상기반 겔선량측정법은 실제 방사선 영역의 체적을 이용 함으로서 겹쳐진 필름을 사용하는 기존 목표 중심점 점검기술의 한계를 보완하였다. 결과적으로, 겔 선량측정법을 이용한 3차원적 목표 중심점 점검기술은 전반적 시스템 점검을 위한 하나의 기술이 될 수 있다.

• Archives of Pharmacal Research
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• 제27권9호
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• pp.901-905
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• 2004

A rapid, sensitive and selective hydrophilic interaction liquid chromatography-tandem mass spectrometric(HILIC-MS/MS) method for the determination of tiapride in human plasma was developed. Tiapride and internal standard, metoclopramide were extracted from human plasma with dichloromethane at basic pH and analyzed on an Atlantis HILIC silica column with the mobile phase of acetonitrile-ammonium formate (190 mM, pH 3.0) (94：6, v/v). The ana-Iytes were detected using an electrospray ionization tandem mass spectrometry in the multi-ple-reaction-monitoring mode. The standard curve was linear (r＝0.999) over the concentration range of 1.00-200 ng/mL. The coefficient of variation and relative error for intra- and inter-assay at three QC levels were 6.4∼8.8％ and -2.0∼3.6％, respectively. The recoveries of tiapride ranged from 96.3 to 97.4％, with that of metoclopramide (internal standard) being 94.2％. The lower limit of quantification for tiapride was 1.00 ng/mL using 1 00 $\mu$L of plasma sample.

• 대한방사선기술학회지:방사선기술과학
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• 제43권6호
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• pp.443-451
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• 2020

This study is to evaluate absorbed dose from right lung for brachytherapy and to estimate the effects of tissue heterogeneities on dose distribution for Iridium-192 source using Monte Carlo simulation. The study employed Geant4 code as Monte Carlo simulation to calculate the dosimetry parameters. The dose distribution of Iridium-192 source in solid water equivalent phantom including aluminium plate or steel plate inserted was calculated and compared with the measured dose by the ion chamber at various distances. And the simulation was used to evaluate the dose of gamma radiation absorbed in the lung organ and other organs around it. The dose distribution embedded in right lung was calculated due to the presence of heart, thymus, spine, stomach as well as left lung. The geometry of the human body was made up of adult male MIRD type of the computational human phantom. The dosimetric characteristics obtained for aluminium plate inserted were in good agreement with experimental results within 4%. The simulation results of steel plate inserted agreed well with a maximum difference 2.75%. Target organ considered to receive a dose of 100%, the surrounding organs were left the left lung of 3.93%, heart of 10.04%, thymus of 11.19%, spine of 12.64% and stomach of 0.95%. When the statistical error is performed for the computational human phantom, the statistical error of value is under 1%.