• Journal of Periodontal and Implant Science
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• v.25 no.2
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• pp.181-191
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• 1995

The ability of fibroblasts attach to teeth is of paramount imporance in re-establishing the lost connective tissue attachment after periodontal therapy. Tobacco contains a complex mixture of substances including nicotine. various nitrousamines, trace elements. and a variety of poorly characterized substances. The effects of nicotine on fibroblasts have reported an altered morphology and attachment of fibroblasts to substrates and disturbances in protein synthesis and secretion. This study examined the effect of nicotine, a major component of the particulate phase of tobacco smoke, on human gingival fibroblasts and periodontal ligament cells attachment to tissue culture surfaces and cellular activity of human gingival fibroblasts and periodontal ligament cells. Pooled human gingival fibroblasts made from extraction of 3rd molar were utilized between passage 4 and 5 and plated in 96 well plate at 20,000 cells per well. Cell number were determined using 3-(4,5-dimethylthiazole-2-y)2,5-diphenyltetrazolium bromide(MTI) , which is reflection of mitochondrial dehydrogenase activity. The concentration of nicotine used were 0.025, 0.05, 0.1, 0.2 and $0.4{\mu}M$, the average serum concentration for a smoker being approximately $0.1{\mu}M$. The results were as follows : 1. Attachment effects of nicotine on human gingival fibroblasts and periodontal ligament cells Excepts of $0.4{\mu}M$, the effects on attachment with increasing numbers of cells attaching with increasing nicotine concentrations, compared to control group. But over the 60min, return to control value. 2. The effect of cellular activity on human gingival fibroblasts and periodontal ligament cells. The cellular activity of human gingival fibroblasts and periodontal ligament cells were similar or decrease to control value at 1st incubation day. At 2nd incubation day, 0.05, 0.1, 0.2, $0.4{\mu}M$ concentrations were statistically different from control value on gingival fibroblasts group. But at 3rd incubation day, cellular activities of all experimental group were significantly decrease than control group.

• The Korean Journal of Physiology and Pharmacology
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• v.13 no.6
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• pp.409-416
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• 2009

Acute pancreatitis is a multifactorial disease associated with the premature activation of digestive enzymes. The genes expressed in pancreatic acinar cells determine the severity of the disease. The present study determined the differentially expressed genes in pancreatic acinar cells treated with cerulein as an in vitro model of acute pancreatitis. Pancreatic acinar AR42J cells were stimulated with $10^{-8}$ M cerulein for 4 h, and genes with altered expression were identified using a cDNA microarray for 4,000 rat genes and validated by real-time PCR. These genes showed a 2.5-fold or higher increase with cerulein: lithostatin, guanylate cyclase, myosin light chain kinase 2, cathepsin C, progestin-induced protein, and pancreatic trypsin 2. Stathin 1 and ribosomal protein S13 showed a 2.5-fold or higher decreases in expression. Real-time PCR analysis showed time-dependent alterations of these genes. Using commercially available antibodies specific for guanylate cyclase, myosin light chain kinase 2, and cathepsin C, a time-dependent increase in these proteins were observed by Western blotting. Thus, disturbances in proliferation, differentiation, cytoskeleton arrangement, enzyme activity, and secretion may be underlying mechanisms of acute pancreatitis.

• Journal of the Korean Home Economics Association
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• v.43 no.3 s.205
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• pp.91-104
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• 2005

This study was designed to examine the relations of home environment, locus of control, social support and behavior problems of fourth-grade Korean-Chinese children in Yanbian in China. The subjects were 190 children who completed the locus of control and social support scale and their parents who completed the Child Behavior Checklist. T-test, correlation analysis, and multiple regression analyses were conducted. Mother's education level, and psychological and physical environment at home were negatively related to children's behavior problems. The scores of internal locus of control and support from the teacher were negatively related to children's behavioral disturbances. The factors with the greatest contribution to explaining behavior problems of Korean-Chinese children in Yanbian were found to be physical environment at home, internal locus of control, and teacher's social support.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.28 no.11
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• pp.1672-1684
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• 2004

In this paper, an active vibration control with the use of an air-cell seat for passenger cars is investigated. The roles of the air-cell inserted between the polyurethane foam of the seat and seat cover are first to extend the seat's capability to adopt various shapes of human body and to improve the ride-comfort against road disturbances. The air-cell seat is modeled as a 1-d.o.f. spring-damper system. Because an exact modeling of the air-cell itself is alomost impossible, its dynamic characteristics are analyzed through experiments. A road-adaptive gain-scheduled sky-hook control for the air-cell seat system is proposed. The skyhook gains are scheduled in such a way that the acceleration level transmitted to human body on various road conditions is minimized. Simulations and experimental results are provided.

• Journal of the Korean Society for Precision Engineering
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• v.28 no.5
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• pp.638-647
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• 2011

Various approaches directly using vibrations of speakers have been suggested to effectively display the aural information such as the music to the hearing-impaired or the deaf. However, in these approaches, the human can't sense the frequency information over the maximum perceivable vibro-tactile frequency (around 1kHz). Therefore, in this study, an approach via spectral modulation of compressing the high frequency audio information into perceivable vibro-tactile frequency domain and outputting the modulated signals through the designated speakers is proposed. Then it is shown, through simulations of using Short-Time Fourier Transform (STFT) with Hanning windows and through preliminary experiments of using the vibro-tactile display testbed which is built and interfaced with a notebook PC, that the modulated signal of a natural sound composing sounds of a frog, a bird, and a water stream could produce the noise-free signal suitable enough for vibro-tactile speakers without causing Significant interfering disturbances, Lastly, for three different combinations of information provided to the subject, that is, i) with only video image, ii) with video image along with the modulated vibro-tactile stimuli as proposed in this study to the forearm of the subject, and iii) with video image along with full audio information, the effects to the human sense of reality and his emotion to given audio-video clips including various sounds and images are investigated and compared. It is shown from results of those experiments that the proposed method of providing modulated vibro-tactile stimuli along with the video images to the human has very high feasibility to transmit pseudo-aural sense to the human.

• Journal of Environmental Science International
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• v.12 no.12
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• pp.1207-1213
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• 2003

Osancheon creek is located in the southwest of the middle area in Korea. Weed community around the Osancheon creek, where various disturbances exert a bad influence directly on its community by human work or nature, was surveyed phytosocialogically. Our surveys have been accomplished from June, 2003 to September, 2003. Weed communities formed around the Osancheon creek were divided into several patterns and analysed. They have been divided into 8 communities. Community A: Humulus japonica community, B: Phragmites communiscommunity, C: Persicaria thunbergii community, D: Zi=ania latifolia community, E: Miscanthus saccharilflorus community, F: Echinochica crusgalli community, G: Typha orientalis community, H: Sataria viridis community. The flora surveyed in these communities was constituted of 19 families, 36 genera, 4 varieties, and 40 species. Wild plants such as Artemisia princeps var. orientalis Erigeron annuus, Bidens frondosa, Aeschynomene indica and Oenothera odorata were mostly light loving plants and higher resistant plants against the disturbance. Our result from the ranking all surveyed areas by the Bray-Curtis ordination method was very similar to the results from phytosocialogical table work.

• Journal of Forest and Environmental Science
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• v.25 no.3
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• pp.177-185
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• 2009

Dryland species and ecosystems have developed unique strategies to cope with low and sporadic rainfall. They are highly resilient and recover quickly from prevailing disturbances such as fires, herbivore pressure and drought. Dryland people have engineered pastoral and farming systems, which are adapted to these conditions and have sustained the livelihoods of dryland people for centuries. In this article, we present the status of potentials and threats to dryland biodiversity and explore options for its conservation and sustainable use. Findings of the research can be summarized as follows: (i) The ecosystem goods and services are highly valued by the community but mechanism for wise use of the resources has disappeared, (ii) forests are under the ownership of the government but the local community is the realistic custodian of the forests through village leaderships and environmental committees; (iii) the immediate major threat to dryland biodiversity held in the forests appears to be the degradation of ecosystems and habitats caused by new and powerful forces of environmental degradation such as large scale irrigation of rice farms, poverty-induced overexploitation of natural resources, and disappearance and ignorance of traditional institutions for management of dryland biodiversity. These new forms of disturbances often overpower the legendary resilience of dryland ecosystems and constitute potentially serious threats to dryland biodiversity. Forests, wetlands and oases all of which are micro hot spots of dryland biodiversity, appear to be particularly vulnerable hence the need to set up some rules and regulations for sustainable utilization of these resources.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.4 no.4
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• pp.36-45
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• 2001

Natural disturbances and human development can cause habitat fragmentation. Plant and wildlife can become isolated, and habitat fragmentation and shrinkage have been recognized as a key issue facing the conservation of biological diversity. However, eco-corridors can alleviate the problem by providing linkages between isolated patches. The purpose of this study is to plan the eco-corridor for connecting urban forest via the urban stream with low cost and to restore the ecosystem. The results were as follows (1) Falco subbuteo, and Dryocopus martius inhabit in the study site. They are protected species designated by Korean Ministry of Environment. Thus the study site should be preserved as urban wildlife habitat species biodiversity (2) If the biodiversity of the study site is maintained properly, the eco-corridor can be constructed with low cost.

• International Journal of Aeronautical and Space Sciences
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• v.18 no.4
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• pp.767-779
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• 2017

Automated mission planning for unmanned aerial vehicles (UAVs) is difficult because of the propagation of several sources of error into the solution, as for any large scale autonomous system. To ensure reliable system performance, we quantify all sources of error and their propagation through a mission planner for operation of UAVs in an obstacle rich environment we developed in prior work. In this sequel to that work, we show that the mission planner developed before can be made robust to errors arising from the mapping, sensing, actuation, and environmental disturbances through creating systematic buffers around obstacles using the calculations of uncertainty propagation. This robustness makes the mission planner truly autonomous and scalable to many UAVs without human intervention. We illustrate with simulation results for trajectory generation of multiple UAVs in a surveillance problem in an urban environment while optimizing for either maximal flight time or minimal fuel consumption. Our solution methods are suitable for any well-mapped region, and the final collision free paths are obtained through offline sub-optimal solution of an mTSP (multiple traveling salesman problem).

• Proceedings of the KIEE Conference
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• 1999.11a
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• pp.28-30
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• 1999

This paper proposes a robust FPID(Fuzzy Proportional Integral Derivative) controller for the LFC(load frequency control) of 2-area power system. The PID gain parameters of the proposed robust FPID controller are self-tuned by PSGM(Product Sum Gravity Method) which is very similiar to human's inference procedures. As the results of simulation, the proposed FPID controller against various load disturbances shows that it is superior to the conventional control techniques such as optimal, PID and fuzzy control in the response characteristics of frequency and tie line power flow.