• Korean Journal of Clinical Laboratory Science
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• v.47 no.3
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• pp.105-111
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• 2015

In late December 2013, the Ebola virus emerged from West Africa. The outbreak started in Guinea and rapidly spread to Liberia and Sierra Leone. Initially, the virus is spread to the human population after contact with infected wildlife and then spread person-to-person through direct contact with body fluids such as blood, sweat, urine, semen, and breast milk. The Ebola virus infects endothelial cells, mononuclear phagocytes and hepatocytes. It causes massive damage to internal tissues and organs, such as blood vessels and the liver, and ultimately death. Most tests for the virus RNA rely on a technology called reverse-transcriptase polymerase chain reaction (RT-PCR). While this method is highly sensitive, it is also expensive, requiring skilled scientists, and delicate power supplies. The strip analytical technique (enzyme-linked immunosorbent assay or ELISA) detects antigens or antibodies to the Ebola virus. This test is cheap and does not require electricity or refrigeration. Despite ongoing efforts directed at experimental treatments and vaccine development, current medical work on the Ebola viral disease is largely limited to supportive therapy. Thus, rapid and reliable diagnoses of the Ebola virus are critically important for patient management, infections, prevention, and control measures.

• Journal of KIISE:Computing Practices and Letters
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• v.10 no.2
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• pp.174-188
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• 2004

In the life environment changed with not only the quality and the price of the products but also the material abundance, it is the most crucial factor for the strategy of product sales to investigate consumer's sensibility and preference degree. In this perspective, it is necessary to design and merchandise the products in cope with each consumer's sensibility and needs as well as its functional aspects. In this paper, we propose the Fashion Design Recommender Agent System (FDRAS-pro) for textile design applying collaborative filtering personalization technique as one of the methods of material development centered on consumer's sensibility and preference. For a collaborative filtering system based on textile, Representative-Attribute Neighborhood is adopted to determine the number or neighbors that will be used for preferences estimation. Pearson's Correlation Coefficient is used to calculate similarity weights among users. We build a database founded on the sensibility adjectives to develop textile designs by extracting the representative sensibility adjectives from users' sensibility and preferences about textile designs. FDRAS-pro recommends textile designs to a customer who has a similar propensity about textile. To investigate the sensibility and emotion according to the effect of design factors, fertile designs were analyzed in terms of 9 design factors, such as, motif source, motif-background ratio, motif variation, motif interpretation, motif arrangement, motif articulation, hue contrast, value contrast, chroma contrast. Finally, we plan to conduct empirical applications to verify the adequacy and the validity of our system.

• Journal of the Korean Society of Clothing and Textiles
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• v.40 no.4
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• pp.669-684
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• 2016

This study investigates Korean fighter pilot's usage and satisfaction of a flight duty uniform (FDU). The survey was conducted from October 2014 to March 2015 using Focus Group Interview (FGI) and questionnaires. FGI collected qualitative data about duty and requirements; subsequently, surveys were performed to collect quantitative data about wearing conditions and satisfaction with FDU. The results of the FGI and the questionnaire were as follows. Type of pilot duty was divided into two parts, flight duty and ground duty. It is important to consider duties as well as factors related to survival when developing FDU. According to anthropometric data and wearing size, the basic size for apparel grading should be changed from actual size, 'M95XL' to 'M100L'. It is also necessary to improve the whole sizing system. Further studies about body form changes in pilot's movement are needed to improve mobility because the respondents perceived some restrictions at several body parts in movement with the coverall uniform. Summer FDU had a low satisfaction level in vent hole function and appearance. Furthermore, protection problems in the vent hole were also an issue. Making a seasonal classification of FDU fabric will be more effective than a vent hole to increase a pilot's thermal satisfaction. Respondents had a passive stance towards FDU reform (including pocket change); therefore, a new FDU design strategy should concentrate on improving current FDU functions like mobility (or comfort) rather than dramatic changes. Pilots complained about the quality stability of FDU; therefore, quality control by military administration as well as concrete and clear design instructions by the developer should be attained together. The results obtained in this study are expected to be used as an important basis for the further development of FDU.

• Analytical Science and Technology
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• v.23 no.2
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• pp.179-186
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• 2010

The oxidative metabolism of ibuprofen in healthy male urine collected at 3, 6, 9, 12 and 15 h after oral administration of ibuprofen was studied by GC/MS assay. To detect conjugated metabolites of ibuprofen, urine sample was acid-hydrolyzed with 6 M HCl at $100^{\circ}C$ for 30 min. To effectively extract ibuprofen and its metabolites, liquid-liquid extraction (LLE) was conducted at pH 3, 5, and 7, respectively. As a result, LLE at pH 3 was shown to be the best extraction condition. For the determination of trace amounts of ibuprofen and its metabolites in extract, trimethylsilylation (TMS) with BSTFA was applied and followed by GC/MS analysis. In this study, main 5 metabolites including parent drug were detected and these metabolites were assigned as three hydroxylated forms and one carboxylated form. Each metabolite was tentatively identified by both interpretation of mass spectrum and comparison with previously reported results. In addition, time profile of urinary excretion rate for parent drugs and metabolites was studied. Finally, the metabolic pathways of ibuprofen were suggested on the basis of the structural elucidation of its metabolites and excretion profiles.

• Analytical Science and Technology
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• v.23 no.6
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• pp.524-530
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• 2010

Chloramphenicol is one of the most effective antibiotics for treatment of food-producing animals for typhoid fever. However, it has been reported that it caused severe side effects such as aplastic anemia in human, therefore the use of chloramphenicol for food-producing animal is prohibited by European Union and other countries. In this study, the analytical method using isotope dilution liquid chromatography-mass spectrometry (ID-LC/MS) was established for accurate determination of chloramphenicol in meat. Chloramphenicol was extracted with ethylacetate from porcine and solid phase extraction cartridge was used for enhancing the recovery. The residue of chloramphenicol in porcine was analyzed using the liquid chromatography mass spectrometer (LC/MS) interfaced with electrospray ionization source. Analysis was performed in negative mode with selected reaction mornitoring mode at m/z 321${\rightarrow}$257 of $[M-H]^-$ ${\rightarrow}$ $[M-H-(HCOCl)]^-$ and m/z 326 ${\rightarrow}$ 262 channels for its isotope. The established method was tested using fortified samples at the level of 0.2 1, 10, $25\;{\mu}g$/kg and analytical results agreed with the gravimetrically fortified values within their uncertainties. This method was validated by analyzing a certified reference material, BCR 445, from IRMM (Institute for Reference Materials and Measurement). Our measurement values agreed with the certified value within their uncertainties. The uncertainty of our measured value was much lower than that the certified value from IRMM.

• Analytical Science and Technology
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• v.30 no.5
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• pp.252-261
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• 2017

Naturally occurring radioactive materials (NORMs) increase radiation exposure to the public as these materials are concentrated through artificial manufacturing processes by human activities. This study focuses on the development of a method for the quantitative analysis of $^{232}Th$, $^{235}U$, and $^{238}U$ in building materials. The accuracy and precision of inductively coupled plasma mass spectrometry (ICP-MS) for determination of digestion processes was evaluated for certified reference materials (CRMs) digested using various mixed acid (e.g., aqua regia, hydrofluoric acid, and perchloric acid) digestions and a $LiBO_2$ fusion method. The method validation results reveal that a $LiBO_2$ fusion and $Fe(OH)_3$ co-precipitation should be applied as the optimal sample digestion process for the quantitative analysis of radionuclides in building materials. The radioactivity of $^{232}Th$, $^{235}U$, and $^{238}U$ in a total of 51 building material (e.g., board, brick, cement, paint, tile, and wall paper) samples was quantitatively analyzed using an established process. Finally, the values of $^{238}U$ and $^{232}Th$ radioactivity were comprehensively compared with those from the indirect method using ${\gamma}$-spectrometry.

• Analytical Science and Technology
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• v.30 no.5
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• pp.270-278
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• 2017

The absorption of blood onto the surfaces of white cotton, polyester, rayon, and nylon fabrics was studied. Different categories of fabrics (woven and knitted) with diverse thickness, were manually folded twice to obtain four fabric layers, and $100{\mu}L$ of human blood was dropped onto the surface of the fabrics. The amount of blood that penetrated the fabric layer and the shape of bloodstain observed on the fabrics were influenced by the chemistry, thickness, and texture of the fabric. The blood bearing fabrics were left to dry for 3 days, washed by hand using tap water, and Lumiscene was then sprayed onto the fabrics to enhance the latent bloodstain for comparison of the shape of the bloodstain before and after washing by hand. The features of the bloodstain after washing varied greatly with the recipient fabrics. Additionally, stronger luminescence was observed at the surface where the blood was deposited compared to the background. However, it was confirmed that physical contact during the washing can deform the original shape of the bloodstain. The effect of the drying time on the bloodstain after hand washing was also studied. $100{\mu}L$ of blood was dropped on the surfaces of the fabrics and dried for 0, 1, 12, 24, 72 h, and 7 days, then washed by hand, before the bloodstain was enhanced with Lumiscene. The results of this experiment indicated that the increased drying time induces stronger chemiluminescence of Lumiscene. However, after drying of the bloodstain for 7 days, the luminescence of the bloodstain was decreased at the blood deposited site and increased around the blood deposited site.

• Korean Journal of Environmental Agriculture
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• v.34 no.4
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• pp.282-287
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• 2015

BACKGROUND: The current study was carried out to investigate Cd, Hg, Pb and As contaminations in 222 commercial medicinal plants and to estimate the potential health risk through dietary intake of commercial medicinal plants in Korea.METHODS AND RESULTS: The Cd, Hg, Pb, and As in medicinal plants were analyzed by ICP/MS and mercury analyzer.The potential health risk was estimated using risk assessment tools. Total amount of Cd in medicinal plants with 29% samples exceeded the standard limit legislated in 'Pharmaceutical Affairs Act' while all plant samples were lower than the standard limit value for As, Hg, and Pb. However, when applying the standard limit for root vegetable (fresh weight) in the Food Sanitation Act, four samples exceeded the standard limit of Pb. For health risk assessment, the values of cancer risk probability were 0.3~5.9×10^-7which were less than the acceptable cancer risk of 10^-6~10^-4for regulatory purpose. Also, Hazard quotientvalues were lower than 1.0.CONCLUSION: Therefore, these results demonstrated that human exposure to Cd, Hg, Pb, and As through dietary intake of commercial medicinal plants might notcause adverse health effects although some medicinal plants were higher than the standard limit values for Cd and Pb.

• Korean Journal of Environmental Agriculture
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• v.28 no.2
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• pp.209-220
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• 2009

Octachlorostyrene(OCS) has been persisted in environment because it has not been decomposed easily. And, it has been known as highly toxic compounds to the environment and human as well as accumulated as high concentrations in a biota through a food chain. Therefore, OCS was monitored for water, soil and fish sampled from the areas where were able to be contaminated with OCS. The recoveries of octachlorostyrene were 93.1${\sim}$98.6% in water, 90.4${\sim}$94.8% in soil and 81.5${\sim}$90.2% in fish and detection limits were 0.0004 mg $L^{-1}$ for water, and 0.002 mg $kg^{-1}$ for soil and fish, respectively. OCS was not detected in water, sediment, soil and fish samples from Ulsan, Yeosu, Daejeon and Sihwa industrial complex and in soil sampled nearby incineration plants in all parts of the country. Accordingly, we estimated that there is no risk from exposure of OCS.

• Science of Emotion and Sensibility
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• v.21 no.1
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• pp.177-186
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• 2018

The mechanism of emotion is complex and influenced by a variety of factors, so that it is crucial to analyze emotion in broad and diversified perspectives. In this study, we classified neutral and negative emotions(sadness, fear, surprise) using arousal evaluation, which is one of the psychological evaluation scales, as well as physiological signals. We have not only revealed the difference between physiological signals coupled to the emotions, but also assessed how accurate these emotions can be classified by our emotional recognizer based on neural network algorithm. A total of 146 participants(mean age $20.1{\pm}4.0$, male 41%) were emotionally stimulated while their physiological signals of the electrocardiogram, blood flow, and dermal activity were recorded. In addition, the participants evaluated their psychological states on the emotional rating scale in response to the emotional stimuli. Heart rate(HR), standard deviation(SDNN), blood flow(BVP), pulse wave transmission time(PTT), skin conduction level(SCL) and skin conduction response(SCR) were calculated before and after the emotional stimulation. As a result, the difference between physiological responses was verified corresponding to the emotions, and the highest emotion classification performance of 86.9% was obtained using the combined analysis of arousal and physiological features. This study suggests that negative emotion can be categorized by psychological and physiological evaluation along with the application of machine learning algorithm, which can contribute to the science and technology of detecting human emotion.