• Journal of Environmental Health Sciences
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• v.46 no.4
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• pp.470-479
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• 2020

Objectives: The Coronavirus Disease 2019 (COVID-19) pandemic has caused the death of 740,000 people around the world as of August 12, 2020. Foot-and-Mouth Disease, Avian Influenza, and African Swine Fever are serious livestock diseases. Government agencies in Korea have provided ingredient information and usage instructions for disinfectants used to counter those infectious diseases. The purpose of this study was to provide information on the chemical ingredients in disinfectant products used against COVID-19 and certain livestock diseases. Methods: We collected information from the Korean government. The Central Disaster Management Headquarters and Central Disease Control Headquarters provided information on disinfectant products used against COVID-19. The Animal and Plant Quarantine Agency of Korea provided information on efficacy-certified disinfectant products for use against selected livestock diseases. Health hazard and environmental hazard information on the ingredients in the disinfectants was collected from the Korea Occupational Safety & Health Agency's Material Safety Data Sheets, and toxicity value information was collected from United States Environmental Protection Agency's CompTox Chemicals Dashboard. Results: There were 76 COVID-19 disinfectant products in use, and the most common ingredients were benzalkonium chloride (51%), alkylbenzyl dimethyl ammonium (30%), and ethanol (3%). There were 216 livestock disease disinfectant products comprised of 89 acidic, 88 oxidic, 30 aldehydic, three alkaline, and six other products. Among the 49 active ingredients used in the disinfectants that were investigated, health and environmental hazard information was provided for many of them, but only 20 chemicals had official toxicological information. Conclusion: Since the disinfectants included numerous chemicals, an understanding of their chemical characteristics could be critical to prevent unintended human or environmental exposure.

• Environmental Analysis Health and Toxicology
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• v.2 no.1_2
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• pp.43-53
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• 1987

Among the environmental toxic metals, cadmium and lead compounds are very hazard for human health because these may affect the biological function of human body and furthermore enhance the cause of various disease. In recent years, as the view of environmental toxicology, the combination of toxic metals suffering human health is especially significant cadmium chloride (10 mg/kg P. 0., 1 mg/kg I.P.) and lead acetate (20 mg/kg P.O., 2 mg/kg I.P.) were administered to rats for 4 weeks on alternate days and then examined the effect of these on body weight, tissue weight and also biochemical function in blood and tissue were investigated and comparision of the two experimental groups such as single and combined administration. According to the results of this experiment, accumulation of heavy metals increased and biological metabolic function grew worse but, in tissue, toxic effect decreased by combined administration and intraperitoneal administration was more toxic than per OS.

• Journal of the Korean Society of Radiology
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• v.10 no.2
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• pp.139-144
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• 2016

The study of radiation-hazard in the human skin tissue is carried out by direct irradiating to experimental animals. The influences of a radiation to the animal's skin tissue are analyzed from this experiment. However, this also accompanies losses in terms of both time and economy. In this study, we simulated human tissue by using a swine skin tissue. The depth of the swine skin tissue for the experiment is determined, and the amount of the direct radiation below this skin depth is analyzed numerically. The amount of the radiation occurred by exposure below the skin tissue can be inferred. Moreover, it is possible to use only cells effectively and animal experiments to analyze the body-hazard by radiation.

• Korean Journal of Environmental Agriculture
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• v.32 no.4
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• pp.245-251
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• 2013

BACKGROUND: The objectives of this study are to investigate the contamination levels of heavy metals in soil, ground water, and agricultural product near the abandoned Boeun and Sanggok mine areas in Korea and to assess the health risk for these local residents exposed to the toxic heavy metals based on analytical data. METHODS AND RESULTS: By the results of human health risk assessment for local residents around Boeun and Sanggok, human exposure to cadmium, copper, arsenic from soil and to lead, cadmium, and arsenic from rice grain were higher in Sanggok, but human exposure to zinc and arsenic from ground water was higher in Boeun. By the results of hazard index (HI) evaluation for arsenic, cadmium, copper, lead, and zinc, HI values in both areas were higher than 1.0. This result indicated that the toxicity hazard through the continuous exposure to lead, cadmium, arsenic from rice, ground water, and soil would be likely to occur to the residents in the areas. Cancer risk assessment for arsenic, risks from the rice were exposed to one to two out of 10,000 people in Boeun and one of 1,000 people in Sanggok. These results showed that the cancer risks of arsenic in both areas were 10~100 times greater than the acceptable cancer risk range of US EPA ($1{\times}10^{-6}{\sim}1{\times}10^{-5}$). CONCLUSION(S): Therefore, if these two local residents consume continuously with arsenic contaminated soil, ground water, and rice, the adverse health effects (carcinogenic potential) would be more increased.

• Environmental Mutagens and Carcinogens
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• v.15 no.2
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• pp.81-87
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• 1995

The clastogenic activity of capsaicin, a major pungent and irritating constituent of hot chili pepper, was evaluated in cultured human lymphocytes. Capsaicin (125, 250, and 500 $\mu$M) caused cytogenetic damage as determined by increased frequency of chromosome/chromatid aberrations compared to the solvent control. The mitotic indices were also decreased in a concentration-related manner in capsaicin-treated cells. Moreover, capsaicin suppressed [$^3$]thymidine incorporation into lymphocytes. The clastogenicity and cytotoxicity of capsaicin towards human lymphocytes were evident without an external metabolic activation system. Taken together, these findings suggest that capsaicin is a genotoxic agent and may thus represent a potential health hazard in humans.

• Journal of the Korean Society of Safety
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• v.14 no.2
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• pp.103-108
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• 1999

This study focused on risk assessment for inhalation of airborne volatile organic compounds (VOCs) in Ulsan industrial complex area. For non-carcinogenic risk, even the highest hazard index of toluene was estimated to be $4.8\times10^{-2}$, which was much lower than 1. The total hazard index of VOCs was estimated to be $5.8\times10^{-2}$. However, lifetime average cancer risk from the inhalation of airborne VOCs was estimated to be about $1.1\times10^{-3}/$, which was much higher than a risk standard of $10^{-5}$. The risk of $4.4\times10^{-5}$. came from benzene, the only human carcinogen among VOCs, while that of $1.05\times10^{-3}$ from probable human carcinogens including 1,3-butadiene and 1,2-dichloroethane. About 70% and 20% of total VOC cancer risk was due to the inhalation of 1,3-butadiene and 1,2-dichloroethane, respectively. Therefore, proper risk management of these 3 VOCs was required for the protection of health from cancer burden in Ulsan industrial complex area.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2001.04a
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• pp.1004-1007
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• 2001

This paper presents the experimental results to verify the environmental consciousness with economic balances due to cutting fluid behaviors, effectiveness in machining process. Even though cutting fluid improves the machined part quality through the cooling and lubracating effects, its environmental impact is also increased according to the cutting fluid usage. Because cutting fluid are used by experience than science on shop floors, its environmental impact are more serious to human health hazard, shop floor environments. In this study a few cutting parameters are adopted as the machinability index (i.e. ; tool wear and surface roughness), and aerosol mist diffusion rate of cutting fluid as the environment consciousness index. These indeces are analyzed quantitatively via a few experiements. The results of this study can be facilitate the optimization of cutting fluid usage in achieving a balanced environmental consciousness consideration with economic view.

• Journal of the Korean Professional Engineers Association
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• v.42 no.5
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• pp.37-40
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• 2009

Engineered nanoparticles are materials purposefully produced with at least one dimension between 1 and 100 nanometers. Nanotechnology has the potential to dramatically improve the effectiveness of a number of existing consumer and industrial products and could have a substantial impact on the development of new products in all sectors. However, nanoparticles is little known about what effect these properties may have on human health. This materials provide an overview of what is known about the potential hazards of engineered nanoparticles and measures that can be taken to minimize workplace exposures.

• Journal of Environmental Science International
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• v.14 no.2
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• pp.121-128
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• 2005

Hexachlorobenzene (HCB) was analyzed in various marine organisms of Korea. HCB was detected in all organism samples with residual concentrations from 0.51 to 222 pg/g wet weight. HCB residue was the highest content in crustacean, and followed by bivalves, fish, cephalopods and gastropods. The residues were comparable to or lower than those in marine organisms of other countries. Daily dietary intake of HCB from seafood was estimated to be 13.4 pg/kg body weight/day. The relative contribution of taxonomic group to the total dietary intake of HCB were in the order of crustaceans $(40.1\%)$, bivalves $(34.2\%)$, fish $(23.1\%)$, cephalopods $(2.22\%)$, and gastropods $(0.38\%)$. Daily dietary intake of HCB expressed as toxic equivalent (TEQ) value was estimated to be $1.34\times10^{-3}pg$ TEQ/kg body weight/day. This value did not exceed tolerable daily intake (TDI) proposed by the WHO, the UK toxicity committee and the KFDA. Cancer risk and target hazard quotient (THQ) due to the consumption of the marine organism in Korean adult population were evaluated using the exposure equation of food ingestion. This result suggests that dietary intake of HCB by the consumption of Korean seafood seems to be safe for human health with negligible cancer and non-cancer risks so far.

• 한국방재학회:학술대회논문집
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• 2008.02a
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• pp.653-655
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• 2008

In order to examine the influences by the extreme weather changes on the human physical conditions, we need to undertake human biometeorology research such as the assesment on the extreme heat's influences on human health. Most of the preceding studied have been found to be focused on the influences by extreme heat on the human body, they used statistics on the daily mortality. But thismethod estimate an indirectly influences by extreme heat on the human body. So, to be able to predict the possible directly influences by the extreme heat on the physical conditions. We measure thermal stress by extreme heat.