• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 춘계학술대회
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• pp.164-166
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• 1996

Human aorta has viscoelastic behavior. The test of tissues such as aorta, skin, muscle, and ok. is required to consider visco effect on deformation behavior. Creep and slow recovery are main aspects of viscoelasticity of tissue engineering. Volumatric strain plays a important role in determine slow recovery of human arota. This study is to suggest the method avoiding viscous effect in tissue experiment The results shows the time scale when the specimen can be fully recovered from slow deformation. Also, this study observes the qualitative creep-effect on elastic strain in 1 minute at the same loading.

• Journal of Pharmaceutical Investigation
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• 제41권3호
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• pp.143-146
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• 2011

Scutellariae Radix is widely used in the traditional herbal medicine for the treatment of fever, cough, dysentery, hepatitis and hypertension in Korea, China and Japan. In this study, we investigated the effects of 70% ethanolic extract of Scutellariae Radix (SRE) on CYP450-mediated drug metabolism in the in vitro systems using human liver microsomes and hepatocytes. The microsomal incubation assay showed that SRE inhibited the drug metabolism reactions catalyzed by CYP1A2, CYP2C8 and CYP2C9 in a dose-dependent manner. In particular, SRE was shown to strongly inhibit the metabolic activity of CYP1A2 with an $IC_{50}$ value of 4.6 ${\mu}g/mL$. When SRE was evaluated for its effect on the induction of CYP450 enzyme activities in cryopreserved human hepatocytes, SRE did not exhibit any effect.

• 한방안이비인후피부과학회지
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• 제12권2호
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• pp.1-19
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• 1999

This study was carried out to prove the effect of GMSKOHG on the cytotoxicity of human monocyte, the inhibition for prostaglandins($PGE_2$) and interleukins($IL-l.{\Beta}$), the produce of $TNF-{\alpha}$, and the size of mouse wounded. The result were obtainde as follows : 1. $0.001\%\;and\;0.0005\%$ of GMSKOHG was not showed the cytotoxicity of human monocyte. 2. $0.01\%\;and\;0.005\%$ of GMSKOHG inhibited the production of interleukins($IL-l{\Beta}$) in the human monocyte, but $0.001\%\;and\;0.0005\%$ of GMSKOHG didn't. 3. $0.001\%$ of GMSKOHG inhibited the production of $TNF-{\alpha}$ in the human monocyte. 4. $0.01\$(MeOH 및 EtOH) of GMSKOHG inhibited the production of prostaglandins($PGE_2$) in the human monocyte. 5. Wound healing was not effect.

• 대한의생명과학회지
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• 제15권2호
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• pp.147-152
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• 2009

Lycopus lucid us Turcz is well known as traditional Chinese medicine, and it has been shown to exhibit antiinflammatory, -allergic and -oxidative effect. However, its anti-cancer properties have not been examined yet. In this study, we investigated the effect of the methanol extract of Lycopus lucid us Turcz on anti-cancer effect in MCF-7 human breast cancer cells. Treatment of Lycopus lucidus Turcz extract induced apoptosis and inhibition of cell proliferation in dose- and time-dependent manner. Apoptosis in the MCF-7 cells was characterized with the changes in nuclear morphology; decrease of Bcl-2 and caspase-7 expression; and increase of cleaved poly ADP-ribose polymerase(PARP). Furthermore, treatment of Lycopus lucidus Turcz extract caused the down-regulation of cell cycle-related protein including, cdk4, cyclin D1 and E2F-1. These results suggest that Lycopus lucidus Turcz might have the therapeutic value against human breast cancer cells.

• 한국균학회지
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• 제6권2호
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• pp.15-18
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• 1978

The study was performed to investigate the inhibitory action on the growth rate of Candida albicans under the various immunological conditions, Candida albicans was grown in broth media containing 0.1ml. (in total broth volume 4.0ml.) of normal human serum, diabetic patient serum, albumin solution, artifical bulla content and nutrient solution as control subject. The inhibitory action of Candida albicans was indicated by mesurement of transparency rate with use of the spectrophotometer. The results are as follows: 1. Normal human serum shows inhibitory effect on the growth of the candida distinctly. 2. Albumin solution reveals almost similar to that of the effect of normal human serum. 3. Artificial bulla content which obtained by irradiation of ultraviolot ray after application of 1% 8-Methoxy-psolaren cream and the diabetic patient serum shows reduction of inhibitory effect as compared with that of the normal human serum. 4. It is estimated that the titer of negative effect of diabetic patient serum is not related with the variation of immunoglobulin titer in patient serum.

• 한국식품영양과학회지
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• 제27권5호
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• pp.987-992
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• 1998

This study was investigated to observe the cytotoxicity effect of Ligularia fischeri extracts against cancer cell lines including human lung carcinoma(A549), human cervix epitheloid carcinoma(HeLa) and human hepatocellular carcinoma(HepG2) using SRB(sulforhodamine B) method. The ethanol and methanol extracts of 1$\mu\textrm{g}$/${mu}ell$ showed approximately 79.2% and 86.4% cytotoxicity effects on HepG2 cell line and the ethyl acetate fracton fractionated from ethanol extracts showed the strongest cytotoxicity effect with 94% inhibition. The inhibitory effect of ethanol extract on HeLa cell line was somewhat low with 50~56% inhibition, but ethyl acetate fraction showed higher cytotoxicity effect with 91% and 91.9% inhibition on the HeLa and A549 cell line. On the contrary, the ethanol and methanol extracts showed the lower inhibition effects on the normal liver cell, WRL68, compared to human cancer cell lines.

• 대한안전경영과학회지
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• 제14권4호
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• pp.333-339
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• 2012

This paper reviewed the relationship between corporate entrepreneurship(innovativeness, risktaking, proactiveness) and managerial innovation(organization innovation, human resource innovation), and the moderating effect of shared vision. The data to verify proposed hypothesis consist of the responses from 243 employees in Kyeong-Gi and Kang-Won province. The results of hierarchical multiple regression analysis showed that innovativeness and proactiveness are related positively with organization innovation and human resource innovation, but risktaking is not related with innovation. Although risktaking has not effect on human resource innovation, it is appeared that it will be positively related with human resource innovation while shared vision is high.

• Journal of Information Display
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• 제13권3호
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• pp.101-106
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• 2012

This study was conducted to enhance the cubic effect by representing an image with a sense of three-dimensional (3D) depth, using chromostereopsis, among the characteristics of human visual perception. An algorithm that enhances the cubic effect, based on the theory that the cubic effect of the chromostereoptic effect and the chromostereoptic reversal effect depends on the lightness of the background, classifies the layers of the 3D image input into the foreground, middle, and background layers according to the depth of the image input. It suits the characteristics of human visual perception because it controls the color factor that was adaptively detected through experiments on each layer; and it can achieve an enhanced cubic effect that is suitable for the characteristics of the image input.

• The Journal of Asian Finance, Economics and Business
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• 제8권5호
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• pp.29-35
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• 2021

This study discusses the effect of human capital and technology on economic growth in Indonesia using annual time series data over the 35-year research period (1984-2019). This study uses an autoregressive distribution gap to the cointegration approach to understanding the relationship between human capital, technology, and economic growth. Human capital is inherent in humans and becomes capital in providing the best performance that has an impact on their own income. We use the human capital framework in this study where education is one mechanism to increase human capital. Based on the results of our estimation, we find that the increase in human capital using the education mechanism affects economic growth. This shows the role of human capital investment is very important in economic growth. Technology shows a significant positive effect on economic growth. Increasing human resources and technology are important factors in efforts to increase economic growth in Indonesia. Educational development is the key to the success of increasing human capital and technological development because education plays a role in improving the quality of human resources. Increasing human resources here is in the form of increased knowledge, mastery of technology, innovation, and the ability to develop technology to encourage technology development.

• 한국항공운항학회지
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• 제24권2호
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• pp.31-46
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• 2016

The purpose of this study is to examine the effects of human touch on turnover intention of ground handling employees at airport. Additionally, this study examines a comprehensive mediating effect of the work schedule and workload between human touch and turnover intention. To examine them, over 700 ground handling employees from six international airports of South Korea were surveyed using the simple random sampling method. The instrument for data collection was a questionnaire, and it was developed based on previous research results. The methodology adopted in this study is the structural equation modeling (SEM). According to SEM analysis, it was proven that both psychological and physical human touch have a significant effect on turnover intention of the employees. Work schedule played a mediating role among all three factors of human touch and turnover intention. However, workload has a mediating effect only between communication human touch and turnover intention. Based on the above findings, theoretical and practical implications are also discussed.