• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3717-3721
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• 2012

Purpose: Any association between the CYP1A1 Ile462Val polymorphism and endometrial cancer risk remains inconclusive. For a more precise estimate, we performed the present meta-analysis. Methods: PUBMED, OVID and EMBASE were searched for the studies which met inclusion criteria. Data in all eligible studies were evaluated and extracted by two authors independently. The meta-analysis estimated pooled odds ratio (OR) with 95% confidence interval (CI) for endometrial cancer risk attributable to the CYP1A1 Ile462Val polymorphism. Results: A total of 7 studies were included in this meta-analysis. The results indicated no association between endometrial cancer risk and the CYP1A1 Ile462Val polymorphism (for Val vs Ile allele model [OR 1.09, 95% CI 0.73-1.62]; for Val.Val vs Ile.Ile genotype model [OR 1.54, 95% CI 0.56-4.23]; for (Ile.Val + Val.Val) vs Ile.Ile genotpye model [OR 1.08, 95% CI 0.71-1.63]; for Val.Val vs (Ile.Ile + Ile.Val) genotype model [OR 1.46, 95% CI 0.53-4.04]). Conclusions: This meta-analysis suggests that there is no association between endometrial cancer risk and the CYP1A1 Ile462Val polymorphism.

• The Bulletin of The Korean Astronomical Society
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• v.43 no.1
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• pp.55.1-55.1
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• 2018

Studies on rotation-powered pulsars with strong surface magnetic field may help us clarify the unclear link between magnetars and canonical radio pulsars because the magnetar-like emission is expected to be observed. PSR J1119-6127 associated with SNR G292.2-0.5 has a high magnetic field of $4.1{\times}1013$ gauss, and a young characteristic age of ~1700 years can be served as the good candidate to compare with magnetars and rotation-powered pulsars. The glitch accompanied by the radiative changes detected in 2007 is the first case we observed for a rotationally powered radio pulsar. This pulsar experienced magnetar-like outbursts in mid. 2016, similar to the 2006 transition occurred on the other radio-quiet rotation-powered pulsar with strong surface magnetic field, PSR J1846-0258. In this talk, I'll report the investigation with X-ray and gamma-ray data of this magnetar-like pulsar. A sudden decrease in the gamma-ray emission at the GeV band was detected immediately after the X-ray outburst. Accompanying with the disappearance of the radio pulsation, the gamma-ray pulsation cannot be resolved as well after the outburst. We tried to derive the timing behavior and some intriguing features of this pulsar in this work corresponding to the outburst using the Swift data, NuSTAR and XMM observations.

• Journal of the Korean Society of Costume
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• v.65 no.7
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• pp.1-18
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• 2015

The purpose of this paper is to compare the body types of Korean-Chinese and Han-Chinese women in their 60's dwelling in Yanbian Korean Autonomous Prefecture. In addition, a survey was conducted to analyze the social and environmental factors that would decide the body types of these two groups of individuals. 1) The comparison of 74 items in physical measurements between the Korean-chinese and Han-chinese showed differences in 36 items. 2) As for the body measurements of women, difference was found between the Han-Chinese and Korean-Chinese in all height items except bust height, circumference, depth, length, and weight. The values of Korean-Chinese were lower than those of Han-Chinese. 3) Cluster analysis shows that Korean- Chinese women appear thinner in regards to common weight, while Han-Chinese women appear to be thicker in regards to with common thinness. 4) Korean-Chinese women dwelling in Yanbian Korean Autonomous Prefecture maintained unique traditional customs and eating habits of Korea and were in constant contact with Korean cultures, which seems to make them care more about body management for health and beauty.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3163-3166
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• 2015

Background: Patients with refractory or relapsed multiple myeloma are considered to have a very poor prognosis, and new regimens are needed to improve this setting. Pomalidomide is a new immunomodulatory drug with high in vitro potency. Immunomodulatory drugs are hypothesized to act through multiple mechanisms. Here we performed a systemic analysis to evaluate pomalidomide-based chemotherapy (pomalidomide in combination with low-dose dexamethasone) as salvage treatment for patients with refractory and relapsed multiple myeloma. Methods: Clinical studies evaluating the efffectiveness of pomalidomide based regimens on response and safety for patients with refractory and relapsed multiple myeloma were identified using a predefined search strategy. Pooled response rate (RR) of treatment were calculated. Results: For pomalidomide based regimens, 4 clinical studies which including 291 patients with refractory and relapsed multiple myeloma were considered eligible for inclusion. Systemic analysis suggested that, in all patients, pooled RR was 41.2% (120/291). Major adverse effects were hematologic toxicity, including grade 1 or 2 anemia, leucopenia and thrombocytopenia with pomalidomide based treatment. No treatment related death occurred. Conclusion: This pooled analysis suggests that pomalidomide in combination with low-dose dexamethasone is active with good tolerability in treating patients with refractory or relapsed multiple myeloma.

• Fisheries and Aquatic Sciences
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• v.23 no.5
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• pp.13.1-13.7
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• 2020

Stock enhancement is considered to be a valuable approach for restoring fishery resources. Because no specific official institution in Taiwan is responsible for the production of fry, the released fry are purchased directly from the private sector. However, fishermen from the private industry have not established a genetic background, so the genetic composition for each batch of released fry is unclear. Mangrove red snapper (Lutjanus argentimaculatus), a prominent species released in Taiwan, was collected after its official release. One hundred and two field samples were compared with four batches of hatchery fry (n = 685) by using a microsatellite-based multiplex PCR assay. Four of the field samples (3.9%; 4/102) were revealed to be from a fish farm and most likely from a single batch. This study revealed that wild mangrove red snappers are genetically different from those originating from farms, and their origins can be traced through molecular markers, even without information on breeding stocks.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.1155-1157
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• 2013

Cancer is a highly complex medical problem with ramifications for public health throughout the world. Most studies have mainly focused on change in the nuclei as being aetiologically responsible. Few have examined the relationship between the cytoplasm and cancer, despite the fact that research has indicated that the cytoplasmic environment is an important factor for cellular differentiation and that the genetic information provided by the nucleus is entirely dependent on this environment for its expression. Gene mutations may be the result, rather than the cause of carcinogenesis. We submit a new concept - "short base sequences" (50-500 bps, including DNA or RNA sequences) in the cytoplasm which could play an important role in carcinogenesis. This is a new theory to explain the origin of the cancer.

• Archives of Plastic Surgery
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• v.44 no.1
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• pp.80-84
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• 2017

Defects involving specialised areas with characteristic anatomical features, such as the nipple, upper eyelid, and lip, benefit greatly from the use of sharing procedures. The vulva, a complex 3-dimensional structure, can also be reconstructed through a sharing procedure drawing upon the contralateral vulva. In this report, we present the interesting case of a patient with chronic, massive, localised lymphedema of her left labia majora that was resected in 2011. Five years later, she presented with squamous cell carcinoma over the left vulva region, which is rarely associated with chronic lymphedema. To the best of our knowledge, our management of the radical vulvectomy defect with a labia majora sharing procedure is novel and has not been previously described. The labia major flap presented in this report is a shared flap; that is, a transposition flap based on the dorsal clitoral artery, which has consistent vascular anatomy, making this flap durable and reliable. This procedure epitomises the principle of replacing like with like, does not interfere with leg movement or patient positioning, has minimal donor site morbidity, and preserves other locoregional flap options for future reconstruction. One limitation is the need for a lax contralateral vulva. This labia majora sharing procedure is a viable option in carefully selected patients.

• Journal of Preventive Medicine and Public Health
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• v.47 no.5
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• pp.281-287
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• 2014

Objectives: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics. However, the adjusted mortality rate of gastric cancer in Minqing was found to be much higher than that in Nanjing. We sought to explore factors associated with this increased risk of gastric cancer between the two counties. Methods: We recruited 231 and 224 residents from Nanjing and Minqing, respectively, and analyzed differences between their dietary habits, Helicobacter pylori infection rates, and concentrations of serum pepsinogen I, pepsinogen II, gastrin-17, and ratio of pepsinogen I:II. Results: Subjects in Minqing had more first-degree relatives who had been diagnosed with upper gastrointestinal tumor, more unhealthy dietary habits, a higher Helicobacter pylori positive rate, and greater proportion of abnormal serum gastrin-17 than those in Nanjing did. Conclusions: The factors that differed between these two counties might indicate that residents in Minqing have a higher risk for developing gastric cancer than those in Nanjing do.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.4
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• pp.1153-1170
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• 2012

Multimedia computing has attracted considerable attention with the rapid growth in the development and application of multimedia technology. Current studies have attempted to support the increasing resource consumption and computational overhead caused by multimedia computing. In this paper, we propose $MediaCloud$, a new multimedia computing paradigm that integrates the concept of cloud computing in handling multimedia applications and services effectively and efficiently. $MediaCloud$ faces the following key challenges: heterogeneity, scalability, and multimedia Quality of Service (QoS) provisioning. To address the challenges above, first, a layered architecture of $MediaCloud$, which can provide scalable multimedia services, is presented. Then, $MediaCloud$ technologies by which users can access multimedia services from different terminals anytime and anywhere with QoS provisioning are introduced. Finally, $MediaCloud$ implementation and applications are presented, and media retrieval and delivery are adopted as case studies to demonstrate the feasibility of the proposed $MediaCloud$ design.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.14 no.7
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• pp.3076-3092
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• 2020

An IKPCA-ELM-based intrusion detection method is developed to address the problem of the low accuracy and slow speed of intrusion detection caused by redundancies and high dimensions of data in the network. First, in order to reduce the effects of uneven sample distribution and sample attribute differences on the extraction of KPCA features, the sample attribute mean and mean square error are introduced into the Gaussian radial basis function and polynomial kernel function respectively, and the two improved kernel functions are combined to construct a hybrid kernel function. Second, an improved particle swarm optimization (IPSO) algorithm is proposed to determine the optimal hybrid kernel function for improved kernel principal component analysis (IKPCA). Finally, IKPCA is conducted to complete feature extraction, and an extreme learning machine (ELM) is applied to classify common attack type detection. The experimental results demonstrate the effectiveness of the constructed hybrid kernel function. Compared with other intrusion detection methods, IKPCA-ELM not only ensures high accuracy rates, but also reduces the detection time and false alarm rate, especially reducing the false alarm rate of small sample attacks.