• International Journal of Computer Science & Network Security
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• v.24 no.4
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• pp.60-66
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• 2024

Host's data during transmission. Data tempering results in loss of host's sensitive information, which includes number of VM, storage availability, and other information. In the distributed cloud environment, each server (computing server (CS)) configured with Local Resource Monitors (LRMs) which runs independently and performs Virtual Machine (VM) migrations to nearby servers. Approaches like predictive VM migration [21] [22] by each server considering nearby server's CPU usage, roatative decision making capacity [21] among the servers in distributed cloud environment has been proposed. This approaches usage underlying server's computing power for predicting own server's future resource utilization and nearby server's resource usage computation. It results in running VM and its running application to remain in waiting state for computing power. In order to reduce this, a decentralized decision making hybrid model for VM migration need to be proposed where servers in decentralized cloud receives, future resource usage by analytical computing system and takes decision for migrating VM to its neighbor servers. Host's in the decentralized cloud shares, their detail with peer servers after fixed interval, this results in chance to tempering messages that would be exchanged in between HC and CH. At the same time, it reduces chance of over utilization of peer servers, caused due to compromised host. This paper discusses, an roatative decisive (RD) approach for VM migration among peer computing servers (CS) in decentralized cloud environment, preserving confidentiality and integrity of the host's data. Experimental result shows that, the proposed predictive VM migration approach reduces extra VM migration caused due over utilization of identified servers and reduces number of active servers in greater extent, and ensures confidentiality and integrity of peer host's data.

• Journal of information and communication convergence engineering
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• v.2 no.2
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• pp.84-88
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• 2004

Firewall is not perfectly prevent hacker, Intrusion Detection System(IDS) is considered a next generation security solution for more trusted network i and system security. We propose a agent IDS model in the different platforms that can detect intrusions in the expanded distributed host environment, since that is a drawback of existing IDS. Then we implement a prototype and verify validity. We use a pattern extraction agent so that we extract audit files needed in intrusion detection automatically even in other platforms.

• Journal of Microbiology and Biotechnology
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• v.21 no.10
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• pp.1026-1035
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• 2011

Vibrio parahaemolyticus, which owes its origin to the marine environment, is considered as one of the most common causes of infectious diarrhea worldwide. The present study investigated the pathogenicity of V. parahaemolyticus against the model organism, Caenorhabditis elegans. Infection in the host was localized with GFP-tagged V. parahaemolyticus using confocal laser scanning microscopy. The times required for causing infection, bacterial load in intestine, chemotactic response, and alteration in pharyngeal pumping were analyzed in the host system. In addition, the regulation of innate immune-related genes, lys-7, clec- 60, and clec-87, was analyzed using real-time PCR. The role of immune-responsible pmk-1 was studied using mutant strains. The pathogenicity of environmental strain CM2 isolated from the Gulf of Mannar, India was compared with that of a reference strain obtained from ATCC. The pathogen infected animals appeared to ward off infection by up-regulating candidate antimicrobial genes for a few hours after the exposure, before succumbing to the pathogen. For the first time, the pathogenicity of V. parahaemolyticus at both the physiological and molecular levels has been studied in detail using the model organism C. elegans.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2017.05a
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• pp.81-81
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• 2017

Nanotechnology is of great importance to molecular biology and medicine because life processes are maintained by the action of a series of molecular nanomachines in the cell machinery. Recent advances in nanoscale materials that possess emergent physical properties and molecular organization hold great promise to impact human health in the diagnostic and therapeutic arenas. In order to be effective, nanomaterials need to navigate the host biology and traffic to relevant biological structures, such as diseased or pathogenic cells. Moreover, nanoparticles intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Inspired by nature, we use peptides to transfer biological trafficking properties to synthetic nanoparticles to achieve targeted delivery of payloads. In this talk, development of nanoscale materials will be presented with a particular focus on applications to three outstanding health problems: bacterial infection, cancer detection, and traumatic brain injury. A biodegradable nanoparticle carrying a peptide toxin trafficked to the bacterial surface has antimicrobial activity in a pneumonia model. Trafficking of a tumor-homing nanoprobes sensitively detects cancer via a high-contrast time-gated imaging system. A neuron-targeted nanoparticle carrying siRNA traffics to neuronal populations and silences genes in a model of traumatic brain injury. Unique combinations of material properties that can be achieved with nanomaterials provide new opportunities in translational nanomedicine. This framework for constructing nanomaterials that leverage bio-inspired molecules to traffic diagnostic and therapeutic payloads can contribute on better understanding of living systems to solve problems in human health.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.14 no.3
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• pp.193-200
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• 2004

The Active Constrained Layer Damping(ACLD) combines the simplicity and reliability of passive damping with the low weight and high efficiency of active control to attain high damping characteristics. The proposed ACLD treatment consists of a viscoelastic damping which is sandwiched between an active piezoelectric layer and a host structure. In this manner, the smart ACLD consists of a Passive Constrained Layer Damping(PCLD) which is augmented with an active control in response to the structural vibrations. The arc type shell model is introduced to describe the interactions between the vibrating host structure, piezoelectric actuator and viscoelastic damping. The system is modeled by applying ARMAX model and changing a state-space form through the system identification method. An optimum control law for the piezo actuator is obtain by LQR(Linear Quadratic Regulator) method. The performance of the ACLD system is determined and compared with PCLD in order to demonstrate the effectiveness of the ACLD treatment. Also, the actuation capability of a piezo actuator is examined experimentally by varying thickness of viscoelastic material(VEM).

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.05a
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• pp.1032-1038
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• 2002

The Active Constrained Layer Damping(ACLO) combines the simplicity and reliability of passive damping with the low weight and high efficiency of active control to attain high damping characteristics. The proposed ACLD treatment consists of a viscoelastic damping which is sandwiched between an active piezoelectric layer and a host structure. In this manner, the smart ACLD consists of a Passive Constrained Layer Damping(PCLD) which is augmented with an active control in response to the structural vibrations. The Arc type shell model is introduced to describe the interactions between the vibrating host structure, piezoelectric actuator and visco damping, The system is modeled by applying ARMAX model and changing a state-space form through the system identification method. An optimum control law for piezo actuator is obtain by LQR(Linear Quadratic Regulator) Method. The performance of ACLD system is determined and compared with PCLD in order to demonstrate the effectiveness of the ACLD treatment, Also, the actuation capability of a piezo actuator is examined experimentally by using various thickness of Viscoelastic Materials(VEM).

• 제어로봇시스템학회:학술대회논문집
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• 1989.10a
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• pp.308-312
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• 1989

We developed a model of NC controller with IBM-PC as a host cpu and integlligent NC servo controller for 2 axes that can be expaned to 4 axes. Basic conceptions, including hardware structure design, servo controller design, communication protocol, and interpolation hardware design was already publicated on '87 KIEE conference. Following this, we focussed on the emulation of tyhe controller with X-Y table as complete NC machine experimenting some drawings made by NC code program that can be edited and executed in automatic on single step mode. In addition we designed the M.S.T functions with PLC and tested for M-function timing. Finally, we designed NC interface to fit with M-function output and we contructed total system of NC controller with IBM PC host with the result of successful development of new NC model.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.9 no.2
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• pp.99-105
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• 2011

An integrated model for groundwater flow and radionuclide transport analyses is being developed incorporating six underground silos, an excavated damaged zone (EDZ), and fractured host rock. The model considers each silo as an engineered barrier system (EBS) consisting of a waste zone comprising waste packages and disposal container, a buffer zone, and a concrete lining zone. The EDZ is the disturbed zone adjacent to silos and construction & operation tunnels. The heterogeneity of the fractured rock is represented by a heterogeneous flow field, evaluated from discrete fractures in the fractured host rock. Radionuclide migration through the EBS in silos and the fractured host rock is simulated on the established heterogeneous flow field. The current model enables the optimization of silo design and the quantification of the safety margin in terms of radionuclide release.

• IMMUNE NETWORK
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• v.9 no.2
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• pp.46-52
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• 2009

Although tuberculosis poses a significant health threat to the global population, it is a challenge to develop new and effective therapeutic strategies. Nitric oxide (NO) and inducible NO synthase (iNOS) are important in innate immune responses to various intracellular bacterial infections, including mycobacterial infections. It is generally recognized that reactive nitrogen intermediates play an effective role in host defense mechanisms against tuberculosis. In a murine model of tuberculosis, NO plays a crucial role in antimycobacterial activity; however, it is controversial whether NO is critically involved in host defense against Mycobacterium tuberculosis in humans. Here, we review the roles of NO in host defense against murine and human tuberculosis. We also discuss the specific roles of NO in the central nervous system and lung epithelial cells during mycobacterial infection. A greater understanding of these defense mechanisms in human tuberculosis will aid in the development of new strategies for the treatment of disease.

• International Journal of Stem Cells
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• v.17 no.1
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• pp.51-58
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• 2024

With the activity of intestinal stem cells and continuous turnover, the gut epithelium is one of the most dynamic tissues in animals. Due to its simple yet conserved tissue structure and enteric cell composition as well as advanced genetic and histologic techniques, Drosophila serves as a valuable model system for investigating the regulation of intestinal stem cells. The Drosophila gut epithelium is in constant contact with indigenous microbiota and encounters externally introduced "non-self" substances, including foodborne pathogens. Therefore, in addition to its role in digestion and nutrient absorption, another essential function of the gut epithelium is to control the expansion of microbes while maintaining its structural integrity, necessitating a tissue turnover process involving intestinal stem cell activity. As a result, the microbiome and pathogens serve as important factors in regulating intestinal tissue turnover. In this manuscript, I discuss crucial discoveries revealing the interaction between gut microbes and the host's innate immune system, closely associated with the regulation of intestinal stem cell proliferation and differentiation, ultimately contributing to epithelial homeostasis.