• Title/Summary/Keyword: Host health

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A study on the difference in the safety culture cognition of host company and subcontractor (주관기업과 협력기업의 안전문화 인식 차이에 관한 연구)

  • Choi, Byung-Gil;Yoon, Seok-Joon;Choi, Seo-Yeon;Moon, Kyoung-Whan
    • Journal of the Korea Safety Management & Science
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    • v.17 no.3
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    • pp.173-183
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    • 2015
  • The study conducted questionnaire analysis on 607 host company employee and 404 subcontractor employee in order to examine the difference in the safety culture cognition of host company and subcontractor. As a result, host company had higher recognition in all safety culture factors compare to that of subcontractor, and there were bigger gap of cognition in the 'cognition in safety status and culture', 'accident and near-miss', 'immediate superior's concentration degree in safety and health' than that of other cognition factors. Furthermore, team leaders showed the highest cognition in both host company and subcontractor, and employees with above 20 year career had the highest cognition in both host company and subcontractor. There is high relationship between host company and subcontractor in the correlations in safety culture cognition factors. Through this study, we identified the difference in the safety culture cognition factor of host company and subcontractor.

Vitamin A: a key coordinator of host-microbe interactions in the intestine

  • Ye-Ji Bang
    • BMB Reports
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    • v.56 no.3
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    • pp.133-139
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    • 2023
  • The human intestine is home to a dense community of microbiota that plays a key role in human health and disease. Nutrients are essential regulators of both host and microbial physiology and function as key coordinators of host-microbe interactions. Therefore, understanding the specific roles and underlying mechanisms of each nutrient in regulating the host-microbe interactions will be essential in developing new strategies for improving human health through microbiota and nutrient intervention. This review will give a basic overview of the role of vitamin A, an essential micronutrient, on human health, and highlight recent findings on the mechanisms by which it regulates the host-microbe interactions.

Microbiome-Linked Crosstalk in the Gastrointestinal Exposome towards Host Health and Disease

  • Moon, Yuseok
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.19 no.4
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    • pp.221-228
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    • 2016
  • The gastrointestinal exposome represents the integration of all xenobiotic components and host-derived endogenous components affecting the host health, disease progression and ultimately clinical outcomes during the lifespan. The human gut microbiome as a dynamic exposome of commensalism continuously interacts with other exogenous exposome as well as host sentineling components including the immune and neuroendocrine circuit. The composition and diversity of the microbiome are established on the basis of the luminal environment (physical, chemical and biological exposome) and host surveillance at each part of the gastrointestinal lining. Whereas the chemical exposome derived from nutrients and other xenobiotics can influence the dynamics of microbiome community (the stability, diversity, or resilience), the microbiomes reciprocally alter the bioavailability and activities of the chemical exposome in the mucosa. In particular, xenobiotic metabolites by the gut microbial enzymes can be either beneficial or detrimental to the host health although xenobiotics can alter the composition and diversity of the gut microbiome. The integration of the mucosal crosstalk in the exposome determines the fate of microbiome community and host response to the etiologic factors of disease. Therefore, the network between microbiome and other mucosal exposome would provide new insights into the clinical intervention against the mucosal or systemic disorders via regulation of the gut-associated immunological, metabolic, or neuroendocrine system.

Host Plant Management Techniques for the Cultivation of Viscum album var. coloratum (Kom.) Ohwi

  • Lee, Bo Duck;Seo, Hyeong Min;Park, Cheol Ho
    • Korean Journal of Plant Resources
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    • v.29 no.6
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    • pp.650-657
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    • 2016
  • Research has found that the management of the host plant is essential to mistletoe cultivation. A Trunk injection test on the host plant that contained a mixture of indole-3-butryc acid (IBA) and liquid fertilizer was conducted with respect to the improvement of the one year survival rate of mistletoe. As a result, the trunk injection experiments showed the effect of the IBA and liquid fertilizer mixture in all treatments. This mixture was effective to increase the survival rate of mistletoe by 20% with the IBA at 100 mg/L and Hyponex at 100 mg/L. The examination proved that the host plant fertilizer effect was the most effective treatment for organic fertilizer with 60% added NPK (4-2-1). Its effects were higher compared to the control at the length and diameter of one-years-old branches in the host plant, even when the parasitic mistletoe improved its growth in length, diameter, and number of branches. Comparing the control and host plant fertilizer, the latter was the most effective way to process 20 kg per a treatment effect in the experimental site and to process at any time after the inoculation. This treatment is effective to improve the growth of mistletoe by watering the host plant three times per week. Therefore, the management of the host plant is an essential element in the successful cultivation of mistletoe, not only to supply fertilizer and plant hormones to the host plant in the initial inoculation time but also to provide organic fertilizer and irrigation for the host plant.

Ophthalmic diseases caused by parasitic infections and its prevention (기생충 감염에 의한 안질환과 예방)

  • Joo, Kyung Bok;Roh, Pyong Ui
    • Journal of Korean Ophthalmic Optics Society
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    • v.7 no.2
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    • pp.223-228
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    • 2002
  • The infection of parasites causes all kinds of parasitosis. The parasites that causes ophthalmic diseases are Protozoa, Nematodes, Cestodes and so on. These parasites has specific connection chains in between parasite and vector, parasite and host, host and host. If these connection chains were polluted or exposed into the worsened environments, the parasite are infected into human body which is its host. The parasite causes the destroy of organic tissues or inflammation and allergic responses by its toxicity and resistance of the host. In worst case, it might cause blindness. In order to prevent these disease, we should keep the clean and clear living environment of every human being.

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Metagenomic Analysis of Chicken Gut Microbiota for Improving Metabolism and Health of Chickens - A Review

  • Choi, Ki Young;Lee, Tae Kwon;Sul, Woo Jun
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.9
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    • pp.1217-1225
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    • 2015
  • Chicken is a major food source for humans, hence it is important to understand the mechanisms involved in nutrient absorption in chicken. In the gastrointestinal tract (GIT), the microbiota plays a central role in enhancing nutrient absorption and strengthening the immune system, thereby affecting both growth and health of chicken. There is little information on the diversity and functions of chicken GIT microbiota, its impact on the host, and the interactions between the microbiota and host. Here, we review the recent metagenomic strategies to analyze the chicken GIT microbiota composition and its functions related to improving metabolism and health. We summarize methodology of metagenomics in order to obtain bacterial taxonomy and functional inferences of the GIT microbiota and suggest a set of indicator genes for monitoring and manipulating the microbiota to promote host health in future.

The Impact of Gut Microbiota in Human Health and Diseases: Implication for Therapeutic Potential

  • Ha, Eun-Mi
    • Biomolecules & Therapeutics
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    • v.19 no.2
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    • pp.155-173
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    • 2011
  • Humans have and hold 100 trillion intestinal bacteria that are essential for health. For millions of years human-microorganisms interaction has co-evolved, and maintained close symbiotic relationship. Gut bacteria contributes to human health and metabolism, and humans provides the optimum nutrition-rich environment for bacteria. What is the mechanism of the host distinguishing the intestinal bacteria as its cohabiting partner and what kind of benefits does the gut microbiota provide the human are the fundamental questions to be asked and solved in order to make human life a higher quality. This review explains the physiological relationship and mutualism between the host and gut microorganism, and highlights the potential therapeutic approach for treating diseases, maintaining and improving health based on these correlations.

Epidemiological Model for Conventional Tobacco Control Measures and Tobacco Endgame Policies

  • Heewon Kang;Sung-il Cho
    • Journal of Preventive Medicine and Public Health
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    • v.56 no.5
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    • pp.481-484
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    • 2023
  • Epidemiological models, also known as host-agent-vector-environment models, are utilized in public health to gain insights into disease occurrence and to formulate intervention strategies. In this paper, we propose an epidemiological model that incorporates both conventional measures and tobacco endgame policies. Our model suggests that conventional measures focus on relationships among agent-vector-host-environment components, whereas endgame policies inherently aim to change or eliminate those components at a fundamental level. We also found that the vector (tobacco industry) and environment (physical and social surroundings) components were insufficiently researched or controlled by both conventional measures and tobacco endgame policies. The use of an epidemiological model for tobacco control and the tobacco endgame is recommended to identify areas that require greater effort and to develop effective intervention measures.

New Bipolar Green Host Materials Containing Benzimidazole-Carbazole Moiety in Phosphorescent OLEDs

  • Park, Jung-Hwan;Kim, Eun-Kyung;El-Deeb, Ibrahim M.;Jung, Su-Jin;Choi, Dae-Hyuk;Kim, Dong-Ha;Yoo, Kyung-Ho;Kwon, Jang-Hyuk;Lee, So-Ha
    • Bulletin of the Korean Chemical Society
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    • v.32 no.3
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    • pp.841-846
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    • 2011
  • New green host materials, 9-phenyl-3-(4-(1-phenyl-1H-benzo[d] imidazol-2-yl)phenyl)-9H-carbazole (3a) and 9-(naphthyl-2-yl)-3-(4-(1-phenyl-1H-benzo[d]imidazol-2-yl)phenyl)-9H-carbazole (3b), have been designed and synthesized by attaching the electron transporting benzimidazole moiety to the hole transporting carbazole unit. These compounds have similar HOMO, LUMO levels and band-gap characteristics compared with CBP (4,4'-di(N-carbazolyl)biphenyl). The fabricated green phosphorescent OLED with this 3a host shows much better device performances compared to CBP-based one. The current and power efficiency is enhanced at least by 60 percent at a given constant luminance of 1000 cd/$m^2$.

Hepatic Steatosis: Prevalence and Host/Viral Risk Factors in Iranian Patients with Chronic Hepatitis B Infection

  • Poortahmasebi, Vahdat;Alavian, Seyed Moayed;Keyvani, Hossein;Norouzi, Mehdi;Mahmoodi, Mahmood;Jazayeri, Seyed Mohammad
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.9
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    • pp.3879-3884
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    • 2014
  • Background: In chronic hepatitis B (CHB), the presence of hepatic steatosis (HS) seems to be associated with known host and viral factors which may influence the long-term prognosis of chronic hepatitis B (CHB), probably leading to cirrhosis and hepatocellular carcinoma (HCC). Different from chronic hepatitis C (CHC), factors associated with HS in CHB are not clearly explored. Materials and Methods: 160 CHB patients were divided into two groups depending on the results of liver biopsy. Group I consisted of 71 patients with confirmed steatosis. Group II comprised 89 patients without steatosis. The groups were compared in terms of basal characteristics, body mass index (BMI), liver enzymes (ALT, AST, ALP), serum fasting blood sugar (FBS) and lipids, hepatitis B e antigen (HBeAg), viral load, and histological findings. Results: In terms of host factors, male gender, older age, BMI, high serum FBS and lipid levels were associated with HS. On the other hand, ALT levels, the HAI scores of necroinflammation and stage of fibrosis did not associate with HS. On multivariate analysis, parameters of sex, BMI, cholesterol and FBS levels were independently associated with HS. Regarding viral factors, HBeAg negativity was significantly associated with HS (81.7%, p value 0.006), but not HBV DNA level (p value 0.520). Conclusions: HS in CHB appears to be unrelated to the status of HBV replication. However, fibrosis progression in CHB is related to variable host factors. HS may be enhanced through these factors in HBV chronic patients.