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http://dx.doi.org/10.4062/biomolther.2011.19.2.155

The Impact of Gut Microbiota in Human Health and Diseases: Implication for Therapeutic Potential  

Ha, Eun-Mi (Department of Pharmacology, College of Pharmacy, Catholic University of Daegu)
Publication Information
Biomolecules & Therapeutics / v.19, no.2, 2011 , pp. 155-173 More about this Journal
Abstract
Humans have and hold 100 trillion intestinal bacteria that are essential for health. For millions of years human-microorganisms interaction has co-evolved, and maintained close symbiotic relationship. Gut bacteria contributes to human health and metabolism, and humans provides the optimum nutrition-rich environment for bacteria. What is the mechanism of the host distinguishing the intestinal bacteria as its cohabiting partner and what kind of benefits does the gut microbiota provide the human are the fundamental questions to be asked and solved in order to make human life a higher quality. This review explains the physiological relationship and mutualism between the host and gut microorganism, and highlights the potential therapeutic approach for treating diseases, maintaining and improving health based on these correlations.
Keywords
Gut microbiota; Host-microbes interaction; Probiotics; Homeostasis; Therapy;
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