• STI Policy Review
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• v.5 no.1
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• pp.98-111
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• 2014

Since Deng Xiaoping's implementation of the "One China, Two Systems" policy, mainland China and the other Chinese regions of Hong Kong and Macau have cooperated in various ways to work towards successfully developing China's overall economy and industries. Particularly, cooperation between Guangdong Province and adjoining Hong Kong have been contributing to China's development, and this study explores their industry conditions including their current two governments policies designed to promote collaboration. The two partners were in a cooperative relationship even before the handover of Hong Kong, beginning with a "front shop, back factory" model built on their respective comparative advantages in labor-intensive industries in the 1980s. This cooperation effectively propelled the Pearl River Delta Region's industrialization process and enabled Hong Kong to transform from a manufacturing industry-based economy to a service industry-based economy. From the early 2000s, Guangdong and Hong Kong diversified their collaboration project from culture to high-tech. Also, both authorities produced several types of policies not only to promote both industries but also to harmonize their two different economic levels and models. As a result, the Guangdong and Hong Kong economies have developed remarkably well during the past two decades and continue to form future plans that carry plenty of optimism. Nonetheless, this study showed discrepancies between engineers and scientists from the two areas in their perception of their technology and science cooperation. Hong Kong experts were more negative in their responses but noted some successes of the collaboration, while Guangdong's group showed overall positive responses. This difference results from an unbalanced role in cooperation. Hong Kong's side responds to cooperation plans and takes on leading roles with more frequency than Guangdong's side in actual cooperation project processes.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.9
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• pp.113-119
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• 2021

With the increasing pressure of international competition, urban agglomeration cooperation and innovation had become an important means of regional economic development. This study analyzed the spatial characteristics of the Urban Cooperative Innovation Network in Guangdong-Hong Kong-Macao Greater Bay Area, found out the dynamic evolution law of innovation, provided suggestions for policy management departments, and effectively planned the industrial layout. According to the data of the State Intellectual Property Office of China, this study researched invention patents from 2005 to 2019. This paper constructed the urban cooperative innovation network, and took 11 cities in the bay area as the research objects, and used social network analysis to study the spatial structure and dynamic evolution of the urban innovation network. Every indicator reflected the urban cooperative innovation, but they all showed a certain decline in 2008-2010. And it is inferred that the innovation network space of each city will be "obvious fist advantages, significant spillover effect and weakening role of Hong Kong and Macao". This paper divided urban cooperative innovation of Guangdong-Hong Kong-Macao Greater Bay Area into three stages. Summing up the characteristics of each stage is helpful to recognize the changes of urban cooperative innovation and to do a good job in industrial layout planning.

• International Journal of Advanced Culture Technology
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• v.9 no.3
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• pp.34-45
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• 2021

On February 18, 2019, the Chinese government officially released the Outline of the Development Plan for the Guangdong-Hong Kong-Macao Greater Bay Area, which will lead the country in a new round of reform and opening-up. The Greater Bay Area will become a dynamic world-class city cluster, an international scientific and technological innovation center with global influence, an important support for the development of the "One Belt And One Road", a demonstration area for in-depth cooperation between the mainland and Hong Kong and Macao, and a high-quality living area for living, working and traveling. Non-Pearl River Delta(Non-PRD) cities in Guangdong Province are adjacent to the Guangdong-Hong Kong-Macao Greater Bay Area, so it is of practical significance to promote the high-quality development of urban tourism from an international perspective. Based on the panel data released in Guangdong Yearbook 2019, this paper uses the envelopment data analysis (DEA) method to explore ways to promote the high-quality tourism development of Non-PRD cities in Guangdong Province based on the perspective of international development.

• Wind and Structures
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• v.15 no.1
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• pp.1-15
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• 2012

High-resolution wind data were acquired from a 100-m high offshore tower during the passage of Typhoon Hagupit in September, 2008. The meteorological tower was equipped with an ultrasonic anemometer and a number of cup anemometers at heights between 10 and 100 m. Wind characteristics of the strong typhoon, such as mean wind speed and wind direction, turbulence intensity, turbulence integral length scale, gust factor and power spectra of wind velocity, vertical profiles of mean wind speed were investigated in detail based on the wind data recorded during the strong typhoon. The measured results revealed that the wind characteristics in different stages during the typhoon varied remarkably. Through comparison with non-typhoon wind measurements, the phenomena of enhanced levels of turbulence intensity, gust factors, turbulence integral length scale and spectral magnitudes in typhoon boundary layer were observed. The monitored data and analysis results are expected to be useful for the wind-resistant design of offshore structures and buildings on seashores in typhoon-prone regions.

• Journal of the Optical Society of Korea
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• v.19 no.1
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• pp.63-68
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• 2015

A one-step fabrication of a photonic crystal (PC) with functional defects is demonstrated. Using multi-beam phase-controlled holographic lithography with a diffracting optical element, large area one dimensional (1D) and two dimensional (2D) PCs with periodic defects were fabricated. The uniform area is up to $2mm^2$, and tens of defect channels have been introduced in the 1D and 2D PC structure. This technique gives rise to substantial reduction in the fabrication complexity and significant improvement in the spatial accuracy of introducing functional defects in photonic crystals. This method can also be used to design and fabricate three dimensional (3D) PCs with periodic defects.

• BMB Reports
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• v.53 no.2
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• pp.82-87
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• 2020

Circular RNAs (circRNAs), one kind of non-coding RNA, have been reported as critical regulators for modulating gene expression in cancer. In this study, microarray analysis was used to screen circRNA expression profiles of bladder cancer (BC) 5637 cells, T24 cells and normal control SV-HUC-1 cells. The data from the microarray showed that hsa_circ_0075828 (named circCASC15) was most highly expressed in 5637 and T24 cells. circCASC15 was highly expressed in BC tissues and cells. Overexpression of circCASC15 was closely associated with BC tumor stage and promoted cell proliferation significantly in vitro and in vivo. Mechanistically, circCASC15 could act as miR-1224-5p sponge to activate the expression of CREB1 to promote cell proliferation in BC. In short, circCASC15 promotes cell proliferation in BC, which might be a new molecular target for BC diagnosis and therapy.

• Asian-Australasian Journal of Animal Sciences
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• v.27 no.1
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• pp.123-130
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• 2014

The A-type lamin deficient mouse line ($Lmna^{-/-}$) has become one of the most frequently used models for providing insights into many different aspects of A-type lamin function. To elucidate the function of Lmna in the growth and metabolism of mice, tissue growth and blood biochemistry were monitored in Lmna-deficient mice, heterozygous ($Lmna^{+/-}$) and wide-type ($Lmna^{+/+}$) backcrossed to C57BL/6 background. At 4 weeks after birth, the weight of various organs of the $Lmna^{-/-}$, $Lmna^{+/-}$ and $Lmna^{+/+}$ mice was measured. A panel of biochemical analyses consisting of 15 serological tests was examined. The results showed that Lmna deficient mice had significantly decreased body weight and increased the ratio of organ to body weight in most of tissues. Compared with $Lmna^{+/+}$ and $Lmna^{+/-}$ mice, $Lmna^{-/-}$ mice exhibited lower levels of ALP (alkaline phosphatase), Chol (cholesterol), CR (creatinine), GLU (glucose), HDL (high-density lipoprotein cholesterol) and higher levels of ALT (alanine aminotransferase) (p<0.05). $Lmna^{-/-}$ mice displayed higher AST (aspartate aminotransferase) values and lower LDL (lowdensity lipoprotein cholesterol), CK-MB (creatine kinase-MB) levels than $Lmna^{+/+}$ mice (p<0.05). There were no significant differences among the three groups of mice with respect to BUN (blood urea nitrogen), CK (creatine kinase), Cyc C (cystatin C), TP (total protein), TG (triacylglycerols) and UA (uric acid) levels (p>0.05). These changes of serological parameters may provide an experimental basis for the elucidation of Lmna gene functions.

• Parasites, Hosts and Diseases
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• v.59 no.2
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• pp.167-171
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• 2021

Haemonchosis remains a significant problem in small ruminants. In this study, the assay of recombinase polymerase amplification (RPA) combined with the lateral flow strip (LFS-RPA) was established for the rapid detection of Haemonchus contortus in goat feces. The assay used primers and a probe targeting a specific sequence in the ITS-2 gene. We compared the performance of the LFS-RPA assay to a PCR assay. The LFS-RPA had a detection limit of 10 fg DNA, which was 10 times less compared to the lowest detection limit obtained by PCR. Out of 24 goat fecal samples, LFS-RPA assay detected H. contortus DNA with 95.8% sensitivity, compared to PCR, 79.1% sensitivity. LFS-RPA assay did not detect DNA from other related helminth species and demonstrated an adequate tolerance to inhibitors present in the goat feces. Taken together, our results suggest that LFS-RPA assay had a high diagnostic accuracy for the rapid detection of H. contortus and merits further evaluation.

• Journal of the Korea Convergence Society
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• v.8 no.7
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• pp.39-46
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• 2017

Dongguan City of Guangdong province, one of the core areas of the Pearl River Delta, has also pursued economic development through the geographical advantage close to Hong Kong. In the early 1980s, small and medium-sized multinational corporations related to home appliances industry from Hong Kong invested to the Dongguan area and set up a production factory. In the mid-1990s, as Taiwanese PC manufacturers invested, local industrial clusters have developed in Dongguan with core of the IT, PC components and electronic industries. The case of the IT industrial cluster in Dongguan is a typical example of the development of Chinese manufacturing industry after the reform of China. This paper focused on the coupling strategy case of Dongguan City industrial cluster in Guangdong province, and theoretically compared the endogenous growth factor analysis(NMID) of regional industrial development with the regional differentiation of industry based on external linkage with global production network(GPN).

• Journal of Korean Society of Rural Planning
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• v.29 no.1
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• pp.19-28
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• 2023

While economic incentives have led to migration, the failure to adapt to a new city and to ease the financial burden to support families have raised migrants' intention to return to their hometowns. Using the 2016 China Migrants Dynamic Survey, this study investigates determinants of migrants' intention to return. Migration at a young age, which is associated with lower barriers to the new culture, and intraprovince migration requiring less effort to adapt to the new city, were associated with lower intention to return. Also, migrants with less burden to support a family tend to have a higher intention to return to rural hometowns. Specifically, migrants with children over 18 years old and fewer family members are likely to return to their hometowns. To revitalize rural economy and reduce the rural-urban disparity, a policy to support migrants with high intention to return will be needed.