• 제목/요약/키워드: History of research

검색결과 5,804건 처리시간 0.038초

유전체 코호트 연구의 윤리적 고려 사항 (Ethical Considerations in Genomic Cohort Study)

  • 최은경;김옥주
    • Journal of Preventive Medicine and Public Health
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    • 제40권2호
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    • pp.122-129
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    • 2007
  • During the last decade, genomic cohort study has been developed in many countries by linking health data and genetic data in stored samples. Genomic cohort study is expected to find key genetic components that contribute to common diseases, thereby promising great advance in genome medicine. While many countries endeavor to build biobank systems, biobank-based genome research has raised important ethical concerns including genetic privacy, confidentiality, discrimination, and informed consent. Informed consent for biobank poses an important question: whether true informed consent is possible in population-based genomic cohort research where the nature of future studies is unforeseeable when consent is obtained. Due to the sensitive character of genetic information, protecting privacy and keeping confidentiality become important topics. To minimize ethical problems and achieve scientific goals to its maximum degree, each country strives to build population-based genomic cohort research project, by organizing public consultation, trying public and expert consensus in research, and providing safeguards to protect privacy and confidentiality.

Study on wind-induced vibration response of Jiayuguan wooden building

  • Teng Y. Xue;Hong B. Liu;Ting Zhou;Xin C. Chen;Xiang Zhang;Zhi P. Zou
    • Wind and Structures
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    • 제37권3호
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    • pp.245-254
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    • 2023
  • In this paper, the wind-induced response of Jiayuguan wooden building (world cultural heritage) in Northwest China was studied. ANSYS finite element software was used to establish four kinds of building models under different working conditions and carry out modal analysis. The simulation results were compared with the field dynamic test results, obtaining the model which reflects the real vibration characteristics of the wooden tower. Time history data of fluctuating wind speed was obtained by MATLAB programming. Time domain method and ANSYS were used to analyze the wind-induced vibration response time history of Jiayuguan wooden building, obtaining the displacement time history curve of the structure. It was suggested that the wind-induced vibration coefficient of Jiayuguan wooden building is 1.76. Through analysis of the performance of the building under equivalent static wind load, the maximum displacement occurs in the three-story wall, gold column and the whole roof area, and the maximum displacement of the building is 5.39 cm. The ratio of the maximum stress value to the allowable value of wood tensile strength is 45 %. The research results can provide reference for the wind resistant design and protection of ancient buildings with similar structure to Jiayuguan wooden tower.

19세기 말 요코하마 외국인거류지의 공간특성 연구 (A Study on the Spatial Characteristic of Yokohama Foreign Concession in the end of 19th Century)

  • 송혜영;김도연;유재우
    • 대한건축학회논문집:계획계
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    • 제34권1호
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    • pp.63-70
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    • 2018
  • The foreign concession of Yokohama was the first downtown formed through the open port of Yokohama. It became a stepping stone to the center of the market economy. Yokohama was regarded as the turning point of modernization in Japanese history and it reached the high light of modern city in Japan. In the nineteenth century the term "open port" which occurred in East Asia was directly connected with modernization. Nevertheless, there is not many researches on architectural history about the central space of the open port city. As the method of research, we examine the parcels and spatial changes that are based on the contents of maps and pictures in terms of architectural history. For the foreign concession that was set up in Yokohama and the first open port in Japan, the spatial scope was set for certain and the temporal range was also set from the setting of the concession in 1859 to the abolition in 1899. The purpose of this study is to consider the future research related to the study of the open port city from the perspective of comparative historical research.

"침구갑을경"에 남아있는 "명당공혈침구치요"의 혈위와 경락배속에 대한 고찰 (Acupoint-Meridian Relationships of the 2nd Century BCE in )

  • 인창식;고형균;이우경;이혜정
    • Korean Journal of Acupuncture
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    • 제27권4호
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    • pp.111-117
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    • 2010
  • Objectives : The acupoint-meridian relationship of an acupoint is one of important features of the acupoint. It has also shown evolutionary development over the history of medicine. This study analyzed the prototype kind of information on acupoint-meridian relationships in the A-B Classic of Acupuncture and Moxibustion(the Classic) of 2c BCE. Methods : The acupoint-meridian relationship of all the acupoints listed in the Classic was counted and reviewed in comparison with the information in the contemporary standard texts. Results : In comparison with the contemporary standard of 361 meridian points, the Classic listed 349(97%) acupoints. Of contemporary standard 361 points, 287(81%) acupoints still maintain the same acupoint-meridian relationship as in the Classic. Conclusions : Acupoint-meridian relationship in the Classic has largely been maintained throughout the history and still comprises a major proportion of the contemporary body of knowledge on acupoint-meridian relationship.

Influence of Environmental Exposures on Patients with Chronic Obstructive Pulmonary Disease in Korea

  • Hong, Yoonki;Lim, Myoung Nam;Kim, Woo Jin;Rhee, Chin Kook;Yoo, Kwang Ha;Lee, Ji-Hyun;Yoon, Ho Il;Kim, Tae-Hyung;Lee, Jin Hwa;Lim, Seong Yong;Lee, Sang Do;Oh, Yeon-Mok
    • Tuberculosis and Respiratory Diseases
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    • 제76권5호
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    • pp.226-232
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    • 2014
  • Background: Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation and results from environmental factors and genetic factors. Although cigarette smoking is a major risk factor, other environmental exposures can influence COPD. The purpose of this study is to investigate the clinical characteristics of COPD according to the history of environmental exposure. Methods: The study population comprised of 347 subjects with COPD who were recruited from the pulmonary clinics of 14 hospitals within the Korean Obstructive Lung Disease Study Group. We classified environmental exposures according to history of living near factory, and direct exposure history to firewood or briquette. According to living environmental exposures, we compared the frequency of respiratory symptoms, pulmonary function, quality of life, exercise capacity, and computed tomography phenotypes. Results: Thirty-one subjects (8.9%) had history of living near factory, 271 (78.3%) had exposure history to briquette, and 184 (53.3%) had exposure history to firewood. Patients with history of living near a factory had a significantly longer duration of sputum, while patients with exposure to firewood tended to have lower forced expiratory volume in one second, and patients with exposure to briquette tended to have lower six minute walk distance. Conclusion: COPD subjects with the history of living near factory had more frequent respiratory symptoms such as sputum. Our data suggest that environmental exposure may influence clinical phenotype of COPD.

Analysis of "The History of Religious Culture" - A Kyrgyz Government Initiative to Prevent Radicalisation and Violent Extremism among Adolescents

  • JAILOBAEVA, KANYKEY;ASILBEKOVA, GULNARA;LATIPOVA, KANYKEI;CHOLPONBAEVA, NAZGUL;UULU, AZAMAT SHARSHENALY;KOLSARIEVA, GULNAZ;BAIALIEVA, MYRZAGUL
    • Acta Via Serica
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    • 제6권1호
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    • pp.31-54
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    • 2021
  • Radicalisation has become an important issue for the Kyrgyz Republic with an increasing number of individuals leaving the country for conflict zones. The government of the Kyrgyz Republic adopted a number of policies to prevent radicalisation and violent extremism among youth. One of these measures is piloting a new subject, titled, History of Religious Culture, (История религиозной культуры) in public schools. The analysis in this paper aims to explore the experiences of teachers, who have taught the new class. The article also examines any differences in the level of resilience of pupils in schools, piloting and not piloting the new subject, towards radicalisation and violent extremism. Data used in this article comes from a survey with 760 adolescents across public schools in six regions of the country and key informant interviews with teachers who have taught the new class. Qualitative findings showed a positive experience of teachers who reported expanding their pupils' and their own knowledge of various religions. Quantitative findings indicate that the new class, History of Religious Culture, may have had a positive impact on violence-related beliefs in pilot schools that reported views less supportive of violence. The study concludes that the government's response to radicalisation and violent extremism has expanded beyond a security approach by including education. This, however, poses a risk of securitising education.

라틴아메리카의 식민경험과 경제성장의 상관관계 (The Relationship Between Colonial Experience and Economic Growth in Latin America)

  • 이상현
    • 이베로아메리카
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    • 제12권1호
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    • pp.241-265
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    • 2010
  • The main purpose of this study is to reveal the historical origins of Latin American economic underdevelopment, by answering two research questions; 1)'Why is Latin America underdeveloped?' and 2)'How has colonial experience impacted on the economic growth in Latin America?' First, this essay analyzes long-term tendency of growth domestic product(GDP) per capita data. The data verify that current underdevelopment of Latin American economy is the result of economic stagnation during the eighteenth and nineteenth centuries, when Latin America suffered political and economic instability before and after the independence from Spain and Portugal. It elucidates that colonial experience affected on the economic growth in Latin America. Second, this essay reviews key independent variables of the relationship between colonial experience and economic growth in Latin America. To do so, the study categorizes extant literature into two groups according to the type of its independent variables: 1)internal factor and 2)external factor. Finally, the essay surveys the role of institutions in Latin American economic growth and development. The survey confirms that the importance of institutions in the study of Latin American economic history. In addition, the essay suggests some tasks for further research in Latin American economic history; 1)the construction of basic economic data, 2)the substantialization of the role and characteristics of institutions, and 3)the expansion of research on institutions which overcomes ideological rigidity of existing institutional approach.

기후변화와 개체의 생활사 (Climate Change and Individual Life History)

  • 이후승
    • Ocean and Polar Research
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    • 제34권3호
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    • pp.275-286
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    • 2012
  • Over the last 20 years there have been more than 3000 peer-reviewed papers relating to climate change and biodiversity published, and still the numbers are increasing. However, most studies focused on the impacts of climate change at population or community levels, and the results invariably reveal that there has been, or will be, a negative effect on the structure and pattern of biodiversity. Moreover, the climate change models and statistical analyses used to test the impacts are only newly developed, and the analyses or predictions can often be misled. In this review, I ask why an individual's life history is considered in the study how climate change affects biodiversity, and what ecological factors are impacted by climate change. Using evidence from a range of species, I demonstrate that diverse life history traits, such as early growth rate, migration/foraging behaviour and lifespan, can be shifted by climate change at individual level. Particularly I discuss that the optimal decision under unknown circumstance (climate change) would be the reduction of the ecological fitness at individual level, and hence, a shift in the balance of the ecosystem could be affected without having a critical impact on any one species. To conclude, I summarize the links between climate changes, ecological decision in life history, the revised consequence at individual level, and discuss how the finely-balanced relationship affects biodiversity and population structure.

Euclid 원론과 Pardies 원론의 비교 연구 (A Comparative Study on Euclid's Elements and Pardies' Elements)

  • 장혜원
    • 한국수학사학회지
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    • 제33권1호
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    • pp.33-53
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    • 2020
  • Euclid's Elements has been considered as the stereotype of logical and deductive approach to mathematics in the history of mathematics. Nonetheless, it has been criticized by its dryness and difficulties for learning. It is worthwhile to noticing mathematicians' struggle for providing some alternatives to Euclid's Elements. One of these alternatives was written by a French scientist, Pardies who called it 'Elemens de Geometrie ou par une methode courte & aisee l'on peut apprendre ce qu'il faut scavoir d'Euclide, d'Archimede, d'Apllonius & les plus belles inventions des anciens & des nouveaux Geometres.' A precedent research presented its historical meaning in traditional mathematics of China and Joseon as well as its didactical meaning in mathematics education with the overview of this book. However, it has a limitation that there isn't elaborate comparison between Euclid's and Pardies'in the aspects of contents as well as the approaching method. This evokes the curiosity enough to encourage this research. So, this research aims to compare Pardies' Elements and Euclid's Elements. Which propositions Pardies selected from Euclid's Elements? How were they restructured in Pardies' Elements? Responding these questions, the researcher confirmed his easy method of learning geometry intended by Pardies.

중국 길림성 화룡시 두도진 연안촌 주거의 평면구성과 평면형식 (A Study on the Plan Composition and Plan Types of the Yanan Village of Toudao Town in Helong City, Jilin Province, China)

  • 김창걸;김왕직
    • 건축역사연구
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    • 제28권1호
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    • pp.17-24
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    • 2019
  • Korean-Chinese is one of the 56 minority groups in the People's Republic of China. Korean-Chinese is the same origin as the Korean Peninsula. In the mid of 19th century, they, who lived in a part of Joseon, suffered with nature disasters and poverty, therefore they offended against the law, immigrated, and started farming in Ching Dynasty, which is northeast China in the present. Later, Korean's individual and mass migrations were happened around coastland of Tumen River and Yalu River with the connivance of the law. This thesis is a consideration of how the Korean-Chinese has adapted before and after the liberation from Japanese colonial era to the Chinese socialism and What their Residential Plan Composition and Plan Types in the village. Based on the field research and literature research, introduces the village history, Plan Composition and sample Plan types. Then, Based on this research, it will be the foundation of the future study of the Korean-Chinese's villages and planning study to conserve the villages.