• Journal of Yeungnam Medical Science
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• v.34 no.1
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• pp.1-10
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• 2017

The life history of man is summarized as a birth-aging-disease-death. Man eventually ages and dies. How long can humans live? What is aging? Why do we age? Is aging inevitable? Can we rejuvenate? Recent researches on biological aging suggest that humans might overcome aging and rejuvenate. In this paper, we review the biologic characteristics of aging and the latest results of biological aging research, implicating that aging can be controlled, further treated, and that humans can ultimately be rejuvenated.

• STI Policy Review
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• v.4 no.1
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• pp.1-13
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• 2013

The Schumpeterian process of "creative destruction", associated with the emergence and diffusion of new radical, so-called "general purpose" technologies, has throughout history impacted wealth and income, jobs creation, jobs displacement, and the emergence and submergence of new hotspots of innovation. Emerging countries have benefited most from such a renewing of those societies' dynamics, leading them to higher levels of economic development and welfare. Doing so they have shown a remarkable capacity in moving upstream in the value chain, from outsourcing of manufacturing activities to autonomous process technology development, product development, design, and applied research. At the same time however, such Schumpeterian processes have now and then turned into exactly opposite processes of "destructive creation." Such processes seem to have become common among what could be called "submerging" economies: innovation only benefitting a few at the expense of many with as a result an opposite pattern of a long term reduction in overall welfare, productivity, and employment growth.

• Restorative Dentistry and Endodontics
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• v.38 no.2
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• pp.90-92
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• 2013

Although periapical inflammatory lesions are usually resulted by infection in the root canal system, this rare case showed that a periapical lesion related to an infected tooth may cause pulpal necrosis in adjacent intact tooth, with no history or clinical signs of caries, disease, trauma or developmental anomaly. This case also suggests that the periapical lesion can be treated conservatively, without surgical intervention. Furthermore, this case highlights the importance of prompt treatment of apical periodontitis before the lesion becomes extensive as well as follows up of large lesions.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.62 no.6
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• pp.881-885
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• 2013

In this paper, we present a deterioration judgment model of urban rail power equipment using driving history, the frequency and number of failures. In addition, we have developed a deterioration judgment program based on the derived failure rate. A deterioration judgment model of power equipments on metro system was designed to establish how much environmental factors, such as thermal cycling, humidity, overvoltage and partial discharge. The deterioration rate of the transformers followed the Arrhenius log life versus reciprocal Kelvin temperature (hotspot temperature) relation. The deterioration judgment program is linked to the online condition monitoring system of urban railway system. The deterioration judgment program is based on the user interface it is possible to apply immediately to the urban rail power equipment.

• STI Policy Review
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• v.3 no.1
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• pp.139-161
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• 2012

The United States National Innovation system has many distinctive aspects and its government research institutes (GRI's) play a variety of important roles within the overall system. This paper reviews issues pertaining to U.S. GRI's but within the broader concept of US science and technology policy. After presenting an overview of the GRI's in this broader context, the paper presents a brief historical analysis of changes in the roles and deployment of U.S. GRI's. After identifying unique features of GRI's (ones that separate the U.S. GRI's from other nations) the paper concludes by identifying the ways in which the U.S. experience may be relevant to other nations such as Korea. The lessons include the competition-cooperation with large-scale and multidisciplinary university research centers, the use of GRI's to promote sharing and efficiencies in fundamental scientific equipment and resources, and the ability of GRI's to accelerate the development of science and technology.

• Mycobiology
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• v.38 no.1
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• pp.65-69
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• 2010

Based on a literature survey and assessment of the important features of lichen genus Buellia (spore shape and size, anatomy of the exciple as well as analysis of the lichen substances), the present paper describes four new records of B. maritima, B. polyspora, B. spuria and B. stellulata from South Korea. Among them, B. maritima and B. polyspora are firstly reported in East Asia including in China, the Korean Peninsula and Japan. Brief description of all the new records along with earlier described species placed under genus Amandinea and Hafellia are provided with their distribution and chemistry. A key to all the Buellia species reported so far from South Korea is also provided.

• Proceedings of the KIEE Conference
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• 2008.10c
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• pp.213-214
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• 2008

Since standardization project is composed of complicate system, such as vehicle, signal, electric power and railway, how to build management system of the project has influence on the success of the project for the first stage of the project. The computer system design tool supports to carry out requirement analysis, DB construction, and history and follow-up management efficiently. Therefore, the aim of this study is to investigate the method to optimize schema using computer system design tool.

• Molecules and Cells
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• v.41 no.10
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• pp.889-899
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• 2018

Intrinsically disordered proteins (IDPs) are highly unorthodox proteins that do not form three-dimensional structures under physiological conditions. The discovery of IDPs has destroyed the classical structure-function paradigm in protein science, 3-D structure = function, because IDPs even without well-folded 3-D structures are still capable of performing important biological functions and furthermore are associated with fatal diseases such as cancers, neurodegenerative diseases and viral pandemics. Pre-structured motifs (PreSMos) refer to transient local secondary structural elements present in the target-unbound state of IDPs. During the last two decades PreSMos have been steadily acknowledged as the critical determinants for target binding in dozens of IDPs. To date, the PreSMo concept provides the most convincing structural rationale explaining the IDP-target binding behavior at an atomic resolution. Here we present a brief developmental history of PreSMos and describe their common characteristics. We also provide a list of newly discovered PreSMos along with their functional relevance.

• Korean Journal of Veterinary Pathology
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• v.3 no.2
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• pp.69-71
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• 1999

A case of chronic cholangiohepatitis associated with Eimeria spp. is reported in a 6-month-old, male, native Korean goat. The goat died after having a 1-week history of diarrhea, anorexia and weight loss. At necropsy, numerous multifocal to coalescing, pale and mottled red foci were present throughout the liver. Histologically, numerous coccidian parasites in both sexual and asexual stages were found in the intrahepatic biliary epithelia and bile duct lumens. Based on the light microscopic and ultrastrastructural features, the parasites present in the liver were compatible with the genus Eimeria ; however, the species was not speciated.

• 한국IT서비스학회:학술대회논문집
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• 2006.11a
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• pp.593-599
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• 2006

Including technical device and general information system, the information-technical(IT) system is defined as the technical system for acquiring, processing, storing and transferring information to a person. This paper presents Knowledge-based Heuristic Evolution Model for creating the advanced information-technical system. This Evolution Model is derived from the historical review on definition of evolution, the research on the architecture of the general IT system, history of IT system, technology innovation theory and multi-case study research. The evolution model is applicable to the conceptual creation of the advanced product in R&D organization requiring development methodologies like rapid-prototyping to develop next generation product. For the detailed theoretical construction and practical application of Evolution Model, the case study research based on action research is performed. the object of the case study is mobile device, especially mobile hand-held phone. Thus, we obtain the Evolution Model for creating the advanced information-technical system.