• Title/Summary/Keyword: High-volume

Search Result 6,458, Processing Time 0.034 seconds

Radiosurgery for Cerebral Arteriovenous Malformation (AVM) : Current Treatment Strategy and Radiosurgical Technique for Large Cerebral AVM

  • Byun, Joonho;Kwon, Do Hoon;Lee, Do Heui;Park, Wonhyoung;Park, Jung Cheol;Ahn, Jae Sung
    • Journal of Korean Neurosurgical Society
    • /
    • v.63 no.4
    • /
    • pp.415-426
    • /
    • 2020
  • Arteriovenous malformations (AVMs) are congenital anomalies of the cerebrovascular system. AVM harbors 2.2% annual hemorrhage risk in unruptured cases and 4.5% annual hemorrhage risk of previously ruptured cases. Stereotactic radiosurgery (SRS) have been shown excellent treatment outcomes for patients with small- to moderated sized AVM which can be achieved in 80-90% complete obliteration rate with a 2-3 years latency period. The most important factors are associated with obliteration after SRS is the radiation dose to the AVM. In our institutional clinical practice, now 22 Gy (50% isodose line) dose of radiation has been used for treatment of cerebral AVM in single-session radiosurgery. However, dose-volume relationship can be unfavorable for large AVMs when treated in a single-session radiosurgery, resulting high complication rates for effective dose. Thus, various strategies should be considered to treat large AVM. The role of pre-SRS embolization is permanent volume reduction of the nidus and treat high-risk lesion such as AVM-related aneurysm and high-flow arteriovenous shunt. Various staging technique of radiosurgery including volume-staged radiosurgery, hypofractionated radiotherapy and dose-staged radiosurgery are possible option for large AVM. The incidence of post-radiosurgery complication is varied, the incidence rate of radiological post-radiosurgical complication has been reported 30-40% and symptomatic complication rate was reported from 8.1% to 11.8%. In the future, novel therapy which incorporate endovascular treatment using liquid embolic material and new radiosurgical technique such as gene or cytokine-targeted radio-sensitization should be needed.

Characteristics for Reinforcement Corrosion and Chloride Ion Diffusion of High Volume Fly Ash Concrete (하이볼륨 플라이애시 콘크리트의 철근부식 및 염소이온 확산 특성)

  • Kwon, Soon-Oh;Bae, Su-Ho;Lee, Hyun-Jin;Jung, Sang-Hwa
    • Journal of the Korean Recycled Construction Resources Institute
    • /
    • v.2 no.1
    • /
    • pp.34-39
    • /
    • 2014
  • The purpose of this experimental research is to evaluate the resistance of reinforcement corrosion and chloride ion penetration of high volume fly ash (HVFA) concrete. For this purpose, concrete test specimens were made for various strength level and replacement ratio of fly ash, and then compressive strength and diffusion coefficient for chloride ion of them were measured for 28, 91 and 182 days, respectively. Also, corrosion monitoring by half cell potential method was carried out for the made lollypop concrete test specimens to detect the time of corrosion initiation for reinforcement in concrete. As a result, it was observed from the test results that compressive strength of HVFA concrete was decreased with increasing replacement ratio of fly ash but long-term resistance against reinforcement corrosion and chloride ion penetration of that was increased.

Effect of Injection Conditions on the Spray Behaviors of the Multi-hole GDI Injector (분사 조건이 다공형 GDI 인젝터의 분무 거동에 미치는 영향)

  • Park, Jeong-Hwan;Park, Su-Han;Lee, Chang-Sik;Park, Sung-Wook
    • Transactions of the Korean Society of Automotive Engineers
    • /
    • v.20 no.2
    • /
    • pp.116-122
    • /
    • 2012
  • The purpose of this study is to investigate the overall spray behavior characteristics for various injection conditions in a gasoline direct injection(GDI) injector with multi-hole. The spray characteristics, such as the spray penetration, the spray angle, and the injection quantity, were studied through the change of the injection pressure, the ambient pressure, and the energizing duration in a high-pressure chamber with a constant volume. The n-heptane with 99.5% purity was used as the test fuel. In a constant volume chamber, the injected spray was visualized by the spray visualization system, which consisted of the high-speed camera, the metal-halide lamp, the injector control device, and the image analysis system with the image processing program. It was revealed that the injection quantity was mainly affected by the difference between the injection pressure and the ambient pressure. For low injection pressure conditions, the injection quantity was decreased by the increase of the ambient pressure, while it nearly maintained regardless of the ambient pressure at high injection pressure. According to the increase of the ambient pressure in the constant volume chamber, the spray development became slow, consequently, the spray tip penetration decreased, and the spray area increased. In additions, the circular cone area decreased, and the vortex area increased.

A study on the grain growth mechanism in dual-phase high Cr-steel (고크롬 (α+γ) 2상강의 결정립 성장기구)

  • Wey, Myeong-Yong
    • Journal of the Korean Society for Heat Treatment
    • /
    • v.11 no.4
    • /
    • pp.324-332
    • /
    • 1998
  • The grain growth characteristics of dual-phase (${\alpha}+{\gamma}$) containing high Cr-steel have investigate using ${\alpha}$-, ${\gamma}$-single phases and (${\alpha}+{\gamma}$)dual-phase of 12%Cr Steel. The heat treatment has performed at $1000-1200^{\circ}C$ for 1-100hr. The results are as follows : 1) The grain growth rate in (${\alpha}+{\gamma}$) dual phase was substantially slower than that of single grain. 2) The relation between mean grain radius $\bar{{\gamma}}$ and annealing time t is, in general, described as following equation : $$(\bar{{\gamma}})^n-(\bar{{\gamma}_o})^n=K_n{\cdot}t{\cdots}{\cdots}(1)$$ i) In the case of single phase of high Cr steel, Eq.(1) is described as $(\bar{{\gamma}})^2-(\bar{{\gamma}_o})^2=K_2{\cdot}t$ and the grain growth is controlled by boundary migration. ii) In dual phase, the grain growth needs diffusion of alloying elements because the chemical composition of ${\alpha}$- and ${\gamma}$- phases differs from each other. When the volume fraction of ${\alpha}$-, ${\gamma}$-phase was almost equal and ${\gamma}$-phase in the case of 80 and $90%{\gamma}$. Eq.(1) is described as $(\bar{{\gamma}})^3-(\bar{{\gamma}_o})^3=K_3{\cdot}t$ because the grain growth is controlled by volume diffusion iii) In the case of ${\gamma}$-rich phase (80 and $90%{\gamma}$), the grain growth of minor phase (10 and $20%{\alpha}$) is described as $(\bar{{\gamma}})^4-(\bar{{\gamma}_o})^4=K_4{\cdot}t$ because the boundary diffusion is predominent rather than volume diffusion.

  • PDF

Basic Study on the Design and Optimization of Sonoreactors for Sonochemical Water/Wastewater Treatment Processes (초음파 수처리 공정 개발을 위한 반응기 설계 기초 연구)

  • Kim, Seulgi;Son, Younggyu
    • Journal of Wetlands Research
    • /
    • v.16 no.2
    • /
    • pp.205-212
    • /
    • 2014
  • Ultrasound technology can be applied in various fields including environmental, energy, and material engineering processes. In this study the effect of liquid height/volume on calorimetric energy and sonochemical oxidation was investigated as one of the basic steps for the design of water/wastereater treatment sonoreactors. The liquid height was increased from 0 to $4{\lambda}$ by $1/4{\lambda}$ and it was found that both calorimetric energy and sonochemical oxidation were significantly increased at relatively high liquid height/volume where the power density was relatively low. The sonochemiluminescence (SCL) images for the visualization of the activity of cavitation also showed that larger and more stable active zone was formed with high SCL intensity at high liquid height/volume. Therefore, it was revealed that sonoreactors for water/wasterwater treatment could be significantly effective in terms of removal efficiency and energy consumption.

Flour Characteristics and End-Use Quality of Korean Wheats with 1Dx2.2+1Dy12 Subunits in High Molecular Weight Glutenin

  • Park, Chul-Soo;Baik, Byung-Kee;Kang, Moon-Seok;Park, Jong-Chul;Park, Jae-Gun;Yu, Chang-Yeon;Choung, Myoung-Gun;Lim, Jung-Dae
    • Preventive Nutrition and Food Science
    • /
    • v.11 no.3
    • /
    • pp.243-252
    • /
    • 2006
  • White salted noodles and pan bread were prepared from Korean wheats with 1Dx2.2+1Dy12 subunits in high molecular weight glutenin subunits (HMW-GS) to evaluate the suitability for end-use products through the comparison with US wheats with various classes and commercial wheat flours. Korean wheat flours with 1Dx2.2+1Dy12 subunits showed higher SDS sedimentation volume than US wheat flours with similar protein content. Compared to wheat flours with similar protein content and SDS sedimentation volume, water absorption percent of Korean wheat flours using a mixograph was higher than that of US wheat flours, but similar to commercial wheat flours. Mixograph mixing time was similar to hard wheat flours and commercial noodle flours. Optimum water absorption percent of noodle dough from Korean wheat flours was higher than that of US wheat flours. Noodle sheets from Korean wheat flours with 1Dx2.2+ 1Dy12 subunits showed lower L values, higher a values and similar b values compared to commercial noodle flours. Hardness of cooked noodles from Korean wheat flours 1Dx2.2+1Dy12 subunits correlated positively with protein content, NIRS hardness, mixograph water absorption and gluten yield of flours. Korean wheat flours with 1Dx2.2+1Dy12 subunits showed lower loaf volume and harder crumb firmness than hard wheat flours and commercial bread wheat flours in spite of similar protein quantity and quality to hard wheat flours.

A Study on the Formation of Air Bubble by the Droplet Volume and Dispensing Method in UV NIL (UV NIL공정에서 액적의 양과 도포방법에 따른 기포형성 연구)

  • Lee, Ki Yeon;Kim, Kug Weon
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.14 no.9
    • /
    • pp.4178-4184
    • /
    • 2013
  • Nanoimprint lithography (NIL) is an emerging technology enabling cost-effective and high-throughput nanofabrication. Recently, the major trends of NIL are high throughput and large area patterning. UV curable type NIL (UV NIL) can be performed at room temperature and low pressure. And one advantage of UV NIL is that it does not need vacuum, which greatly simplifies tool construction, so that vacuum oprated high-precision stages and a large vacuum chamber are no longer needed. However, one key issue in non-vacuum environment is air bubble formation problem. Namely, can the air bubbles be completely removed from the resist. In this paper, the air bubbles formation by the method of droplet application in UV NIL with non-vacuum environment are experimentally studied. The effects of the volume of droplet and the number of dispensing points on air bubble formation are investigated.

Variation of optimization techniques for high dose rate brachytherapy in cervical cancer treatment

  • Azahari, Ahmad Naqiuddin;Ghani, Ahmad Tirmizi;Abdullah, Reduan;Jayamani, Jayapramila;Appalanaido, Gokula Kumar;Jalil, Jasmin;Aziz, Mohd Zahri Abdul
    • Nuclear Engineering and Technology
    • /
    • v.54 no.4
    • /
    • pp.1414-1420
    • /
    • 2022
  • High dose rate (HDR) brachytherapy treatment planning usually involves optimization methods to deliver uniform dose to the target volume and minimize dose to the healthy tissues. Four optimizations were used to evaluate the high-risk clinical target volume (HRCTV) coverage and organ at risk (OAR). Dose-volume histogram (DVH) and dosimetric parameters were analyzed and evaluated. Better coverage was achieved with PGO (mean CI = 0.95), but there were no significant mean CI differences than GrO (p = 0.03322). Mean EQD2 doses to HRCTV (D90) were also superior for PGO with no significant mean EQD2 doses than GrO (p = 0.9410). The mean EQD2 doses to bladder, rectum, and sigmoid were significantly higher for NO plan than PO, GrO, and PGO. PO significantly reduced the mean EQD2 doses to bladder, rectum, and sigmoid but compromising the conformity index to HRCTV. PGO was superior in conformity index (CI) and mean EQD2 doses to HRCTV compared with the GrO plan but not statistically significant. The mean EQD2 doses to the rectum by PGO plan slightly exceeded the limit from ABS recommendation (mean EQD2 dose = 78.08 Gy EQD2). However, PGO can shorten the treatment planning process without compromising the CI and keeping the OARs dose below the tolerance limit.

Hydration and Mechanical Properties of High-volume Fly Ash Concrete with Nano-silica (나노 실리카를 혼입한 하이볼륨 플라이애시 콘크리트의 수화도 및 역학적 특성)

  • Cha, Soo-Won;Lee, Geon-Wook;Choi, Young-Cheol
    • Journal of the Korea institute for structural maintenance and inspection
    • /
    • v.26 no.6
    • /
    • pp.112-119
    • /
    • 2022
  • Recently, as carbon neutrality has been important factor in the construction industry, many studies have been conducted on the high-volume fly ash concrete. High volume fly ash concrete(HVFC) is usually made by replacing more than 50% of cement with fly ash. However, HVFC has a disadvantage of low compressive strength in early age. To overcome this shortcoming of HVFC, improve this, interest in techonolgy using nanomaterials is increasing. Nano silica is expected to improve the early age strength of HVFC as a pozzolanic material. This study investigated the effect of nano silica on the early hydration reaction and microstructure of HVFC. The early hydration reaction of HFVC was analyzed through setting time, isothermal calorimeter, compressive strength and thermal weight analysis. In addition, the microstructure of HVFC was measured by mercury intrusion porosimetry. From the test results, it was confirmed that nano silica increased the early age strength and improve the microstructure of HVFC.

Resistance Analysis by Distribution of Relaxation Time According to Gas Diffusion Layers and Binder Amounts for Cathode of High-temperature Polymer Electrolyte Membrane Fuel Cell (고온 고분자 막 전해질 연료전지 캐소드의 가스 확산층 및 바인더 함량에 따른 완화 시간 분포(DRT) 저항 분석)

  • DONG HEE KIM;HYOEN SEUNG JUNG;CHANHO PAK
    • Journal of Hydrogen and New Energy
    • /
    • v.34 no.3
    • /
    • pp.283-291
    • /
    • 2023
  • The physical properties were analyzed for four gas diffusion layers, and gas diffusion electrodes (GDEs) for the cathode of high-temperature polymer electrolyte membrane fuel cell were fabricated through bar coating with three binder to carbon (B/C) ratios. Among them, The GDE from JNT30-A6P showed a significant change in secondary pore volume at a B/C ratio of 0.31, which had the largest pore volume among all GDEs. In the polarization curve, JNT30-A6P GDE showed the best membrane electrode assembly (MEA) performance with a peak power density of 384 mW/cm2 at a a B/C ratio of 0.31. From the distribution of relaxation time analysis, the peak 1 corresponding to mass transfer resistance of oxygen reduction reaction (ORR) was significantly reduced in the JNT30-A6P GDE. This is the result that when the binder content decreased, the volume of the secondary pore increased, and the mass transfer resistance of ORR decreased, which played an essential role in the MEA performance.