• Journal of the Institute of Electronics Engineers of Korea TC
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• v.45 no.9
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• pp.8-12
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• 2008

In this paper, we proposes a D-STTD(Double-Space Time Transmit Diversity) communication system with AMC scheme and analyzes its performance using simulation experiments. The AMC scheme selects an optimal channel coding rate and modulation scheme based on the channel response data for signal transmission, creating a balance between error rate and throughput to improve the overall system throughput and transmission quality. The D-STTD scheme complements the conventional STTD(Space Time Transmit Diversity) scheme, yielding about twice the throughput. The simulation results show that the probability of selecting a high MCS(Modulation and Coding Scheme) level increased as the SNR(Signal to Noise Ratio) improved. Furthermore, the D-STTD communication system with AMC scheme provided a more uniform throughput distribution throughout the entire SNR range compared to its counterpart which did not apply AMC scheme. Also, the maximum throughput of the D-STTD communication system with AMC scheme was twice that of a conventional AMC communication system or a STTD communication system with AMC scheme.

• Toxicological Research
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• v.25 no.2
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• pp.59-69
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• 2009

Metabolomics which deals with the biological metabolite profile produced in the body and its relation to disease state is a relatively recent research area for drug discovery and biological sciences including toxicology and pharmacology. Metabolomics, based on analytical method and multivariate analysis, has been considered a promising technology because of its advantage over other toxicogenomic and toxicoproteomic approaches. The application of metabolomics includes the development of biomarkers associated with the pathogenesis of various diseases, alternative toxicity tests, high-throughput screening (HTS), and risk assessment, allowing the simultaneous acquisition of multiple biochemical parameters in biological samples. The metabolic profile of urine, in particular, often shows changes in response to exposure to xenobiotics or disease-induced stress, because of the biological system's attempt to maintain homeostasis. In this review, we focus on the most recent advances and applications of metabolomics in toxicological research.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.4
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• pp.893-910
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• 1996

Recently, there ary many researches on local area multichannel network as WDM technology developes. An ideal media access protocol in a multichannel network is one that shows short access delay under low load and high throughput under heavy load. This paper proposed a new media access protocol for WDM passive star coupler network. The proposed one is a random access rpotocol based on reservation. Access delay is short under low load by using random access method, and high throughput is achieved under heavy load by usin greservation access. Analytic model for the performance analysis of the proposed protocol is developed and performance of the proposed protocol is compared with the previous ones. The effect on the performance of the number of the nodes and channels, and the number of transceivers in each node are analyzed.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2000.11a
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• pp.45-52
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• 2000

Genomic approach produces massive amount of data within a short time period, New high-throughput automatic sequencers can generate over a million nucleotide sequence information overnight. A typical DNA chip experiment produces tens of thousands expression information, not to mention the tens of megabyte image files, These data must be handled automatically by computer and stored in electronic database, Thus there is a need for systematic approach of data collection, processing, and analysis. DNA sequence information is translated into amino acid sequence and is analyzed for key motif related to its biological and/or biochemical function. Functional genomics will play a significant role in identifying novel drug targets and diagnostic markers for serious diseases. As an enabling technology for functional genomics, bioinformatics is in great need worldwide, In Korea, a new functional genomics project has been recently launched and it focuses on identi☞ing genes associated with cancers prevalent in Korea, namely gastric and hepatic cancers, This involves gene discovery by high throughput sequencing of cancer cDNA libraries, gene expression profiling by DNA microarray and proteomics, and SNP profiling in Korea patient population, Our bioinformatics team will support all these activities by collecting, processing and analyzing these data.

• Korean Journal of Ichthyology
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• v.34 no.1
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• pp.8-15
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• 2022

The appearance of larvae of a rare species, Peristedion liorhynchus, in Korean waters is suggestive of spawning or adult intrusion. We conducted high-throughput sequencing (HTS) on 31,776 pelagic fish eggs collected from 123 stations off the Korean Peninsula during May to August in 2013, 2014 and 2017. A total of 21,621,874 HTS reads were mapped onto the P. liorhynchus COX1 reference sequence. Three consensus sequences (313 bp) were constructed from the three samples, respectively, off Uljin and Goeje Islands in May and off Ulsan in July. These samples were formed a clade with P. liorhynchus in the maximum likelihood tree of Peristedion. The average genetic distance within the P. liorhynchus clade (0.0054±0.0046) was less than that among clades (0.1475±0.0396). The results indicate that the HTS analysis of mixed fish eggs is useful for monitoring the intrusion of rare species such as P. liorhynchus in Korean waters.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.42 no.2
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• pp.383-385
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• 2017

For the purpose of providing high data rate real-time services, radio transmission technologies for ship ad-hoc network based on the Recommendation ITU-R 1842-1 are designed. In order to increase the link throughput of real-time services, in this paper, we investigate the performance of the SANET with the spatial transmit diversity techniques are employed. Based on the analysis of the packet error rate and throughput, we select the efficient multiple antenna schemes for SANET to improve the link reliability.

• Journal of Microbiology and Biotechnology
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• v.26 no.2
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• pp.213-225
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• 2016

To reduce attrition in drug development, it is crucial to consider the development and implementation of translational phenotypic assays as well as decipher diverse molecular mechanisms of action for new molecular entities. High-throughput fluorescence and confocal microscopes with advanced analysis software have simplified the simultaneous identification and quantification of various cellular processes through what is now referred to as high-content screening (HCS). HCS permits automated identification of modifiers of accessible and biologically relevant targets and can thus be used to detect gene interactions or identify toxic pathways of drug candidates to improve drug discovery and development processes. In this review, we summarize several HCS-compatible, biochemical, and molecular biology-driven assays, including immunohistochemistry, RNAi, reporter gene assay, CRISPR-Cas9 system, and protein-protein interactions to assess a variety of cellular processes, including proliferation, morphological changes, protein expression, localization, post-translational modifications, and protein-protein interactions. These cell-based assay methods can be applied to not only 2D cell culture but also 3D cell culture systems in a high-throughput manner.

• Proceedings of the Korean Magnestics Society Conference
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• 2016.11a
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• pp.162-162
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• 2016

• Proceedings of the PSK Conference
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• 2002.04a
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• pp.212.1-212.1
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• 2002

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.12 no.5
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• pp.810-816
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• 2001

This paper proposes a Truncated Type-II Hybrid ARQ scheme using an adaptive modulation system to achieve high throughput data transmission systems for mobile communication systems. In this paper, the adaptive modulation system analyzed in Nakagami (m-distribution) fading channel environment. The adaptive modulation system controls the modulation level and symbol rate according to the Nakagami fading parameter(m). When the received $E_bN_0$ is high or the Nakagami fading parameter m is high, the propose system selects higher modulation level and higher symbol rate to increase throughput. On the other hand, this system selects lower modulation level and lower symbol rate to prevent throughput performance degradation when the received $E_bN_0$ is low. The modulation method have been adopted QPSK(Quadrature Phase Shift Keying), 16 QAM(Quadrature Amplitude Modulation), 64 QAM, 256 QAM. Therefore, Adaptive Modulation Systems with Truncated Type-II Hybrid ARQ Scheme is proper for mobile and radio for mobile and radio data communication system that require high reliability and delay-limited applications.