• 제목/요약/키워드: High-throughput analysis

검색결과 555건 처리시간 0.033초

Rapid and massive throughput analysis of a constant volume high-pressure gas injection system

  • Ren, Xiaoli;Zhai, Jia;Wang, Jihong;Ren, Ge
    • Nuclear Engineering and Technology
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    • 제51권3호
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    • pp.908-914
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    • 2019
  • Fusion power shutdown system (FPSS) is a safety system to stop plasma in case of accidents or incidents. The gas injection system for the FPSS presented in this work is designed to research the flow development in a closed system. As the efficiency of the system is a crucial property, plenty of experiments are executed to get optimum parameters. In this system, the flow is driven by the pressure difference between a gas storage tank and a vacuum vessel with a source pressure. The idea is based on a constant volume system without extra source gases to guarantee rapid response and high throughput. Among them, valves and gas species are studied because their properties could influence the velocity of the fluid field. Then source pressures and volumes are emphasized to investigate the volume flow rate of the injection. The source pressure has a considerable effect on the injected volume. From the data, proper parameters are extracted to achieve the best performance of the FPSS. Finally, experimental results are used as a quantitative benchmark for simulations which can add our understanding of the inner gas flow in the pipeline. In generally, there is a good consistency and the obtained correlations will be applied in further study and design for the FPSS.

Combined Application Effects of Arbuscular Mycorrhizal Fungi and Biochar on the Rhizosphere Fungal Community of Allium fistulosum L.

  • Chunxiang Ji;Yingyue Li;Qingchen Xiao;Zishan Li;Boyan Wang;Xiaowan Geng;Keqing Lin;Qing Zhang;Yuan Jin;Yuqian Zhai;Xiaoyu Li;Jin Chen
    • Journal of Microbiology and Biotechnology
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    • 제33권8호
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    • pp.1013-1022
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    • 2023
  • Arbuscular mycorrhizal fungi (AMF) are widespread soil endophytic fungi, forming mutualistic relationships with the vast majority of land plants. Biochar (BC) has been reported to improve soil fertility and promote plant growth. However, limited studies are available concerning the combined effects of AMF and BC on soil community structure and plant growth. In this work, a pot experiment was designed to investigate the effects of AMF and BC on the rhizosphere microbial community of Allium fistulosum L. Using Illumina high-throughput sequencing, we showed that inoculation of AMF and BC had a significant impact on soil microbial community composition, diversity, and versatility. Increases were observed in both plant growth (the plant height by 8.6%, shoot fresh weight by 12.1%) and root morphological traits (average diameter by 20.5%). The phylogenetic tree also showed differences in the fungal community composition in A. fistulosum. In addition, Linear discriminant analysis (LDA) effect size (LEfSe) analysis revealed that 16 biomarkers were detected in the control (CK) and AMF treatment, while only 3 were detected in the AMF + BC treatment. Molecular ecological network analysis showed that the AMF + BC treatment group had a more complex network of fungal communities, as evidenced by higher average connectivity. The functional composition spectrum showed significant differences in the functional distribution of soil microbial communities among different fungal genera. The structural equation model (SEM) confirmed that AMF could improve the microbial multifunctionality by regulating the rhizosphere fungal diversity and soil properties. Our findings provide new information on the effects of AMF and biochar on plants and soil microbial communities.

분산망에 기반한 ATM 교환기으 설계한 성능 분석 (Design and Analysis of Distributed-Network-Based ATM Switch : Weaved GSN)

  • 이형일;정한유;서승우
    • 한국통신학회논문지
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    • 제25권1A호
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    • pp.56-63
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    • 2000
  • 본 논문에서는 분산망의 일종인 GSN에 기반한 ATM 교환기를 제안한다. 원하는 셀 손실율을 얻기 위해서 여러 장의 GSN을 병렬적으로 배치하고 인접한 GSN에서 동일한 위치의 교환 소자간에 연결선을 가지는 Weaved GSN 구조를 제안한다. Weaved GSN은 단순히 여러 장의 GSN을 병렬화하는 것보다 지연 시간과 hardware complexity 면에서 뚜렷한 향상을 보인다. 균일한 독립적인 traffic을 가정하고 이론적 분석과 모의 실험의 결과들을 통하여, WGSN이 지금까지 제안된 반얀망에 기반한 다른 교환기 구조에 비하여 향상된 수율과 셀 손실율을 얻을 수 있음을 보인다.

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다중경로 페이딩 채널에서 DAC 양자화 오차에 대한 IEEE P802.15.3a 멀티밴드 UWB 송수신기 성능 분석 (Performance Analysis of IEEE P802.15.3a Multi-band UWB Transceiver for DAC Quantization Error in Fading Channel)

  • 정성원;이승윤;임승호;박규호
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2003년도 통신소사이어티 추계학술대회논문집
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    • pp.216-219
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    • 2003
  • In this paper, we present performance analysis of an IEEE P802.15.3a high rate wireless personal area network transceiver. This physical layer standard uses QOSK as its sub-channel modulation scheme and orthogonal frequency domain modulation (OFDM) for sub-bands. OFDM is used for each sub-band so that multi-path effects are absorbed by equalizer and guard, and fading can be approximately modeled as additive white Gaussian noise. In multi-band ultra-wideband system, DAC quantization error is important noise source since high resolution conversion cannot be used due to high power consumption. Simulation result shows that, to get 640-Mbps throughput, at least 5-bits precision is necessary to maintain bit-error rate under 10$\^$-2/, which can be lowered, with channel coding, to 10$\^$-6/ that is the bit-error rate required by IEEE 802.15 upper protocol layer, in 4-meter LOS fading channel.

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사회연결망 분석을 활용한 컨테이너 정기선 항로 변화 분석: 인천항을 중심으로 (Analysis of the Changes of Liner Service Networks by Using SNA: Focused on Incheon Port)

  • 박기현;임미순;안승범
    • 한국항만경제학회지
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    • 제32권1호
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    • pp.97-122
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    • 2016
  • 현재 인천항은 국내 컨테이너 처리물동량 3위 항만으로 2013년~2014년 컨테이너 처리 물동량 200만 TEU를 달성하였으며 국내 컨테이너 처리 물동량 2위인 광양항과의 물동량 차이를 줄이며 국내 2위 컨테이너 항만으로 도약하기 위해 노력하고 있다. 또한 지속적인 컨테이너 물동량 증가에 대비하여 2015년 6월 인천 송도에 인천 신항을 개장하며 국내 및 세계 주요 컨테이너항만으로 발전하기 위한 발판을 마련하였다. 이처럼 인천항의 컨테이너 항만으로서의 역할이 커지고 있어 인천항을 기항하고 있는 컨테이너 정기선 항로(항만 네트워크)의 역할과 향후 방향성 설정에 대한 관심이 늘어나고 있다. 본 연구는 인천항을 기항하는 컨테이너 정기선 항로를 중심으로 하는 시계열 자료(2008년~2015년)를 분석하여 인천항 컨테이너 정기선 항로의 변화에 대해 확인 하였으며 이를 통해 남중국/동남아시아 항로의 증가세가 인천항 컨테이너 정기선 항로의 증가에 긍정적 영향을 미쳤다는 점과 2008년도에 비해 인천항 컨테이너 정기선 항로의 다변화가 이루어지고 있음을 확인하였다. 그리고 최근 해운 항만 분야에 도입되고 있는 사회연결망분석(Social Network Analysis)을 통해 인천항 컨테이너 정기선 항로상의 중앙성(Centrality) 분석을 시행하였다. 인천항 컨테이너 정기선 항로상에 연결정도 중앙성(degree centrality), 인접 중앙성(closeness centrality), 사이 중앙성(betweenness centrality)이 높은 항만 및 그 변화를 확인하였으며, 이를 통해 국내에는 부산항이 국외에는 홍콩항이 높은 중심성(Centrality)을 가지는 것으로 나타났다. 이를 통해 인천항의 네트워크상 허브 항만은 세계 컨테이너 물동량 순위(14년 기준) 1위, 2위를 차지하는 상해, 싱가포르가 아님을 확인하였으며, 또한 중국 동부 항만의 중심성이 상대적으로 낮은 점에서 현재까지 중국 동부 항만이 인천항의 네트워크상 허브 역할을 하지 않고 있음을 확인하였다.

Rapid Determination of Ginkgolic Acids in Ginkgo biloba Leaf Using Online Column Switching High-Performance Liquid Chromatography-Diode Array Detection and Confirmation by Liquid Chromatography-tandem Mass Spectrometry

  • Lee, Hyounyoung;Lim, Heungyoul;Yang, Juhong;Hong, Jongki
    • Bulletin of the Korean Chemical Society
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    • 제34권12호
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    • pp.3629-3634
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    • 2013
  • In this study, an improved method for the quantitative analysis of ginkgolic acids (GAs) in Ginkgo biloba leaf extract was developed. The samples were extracted with a mixture of chloroform and 50 % ethanol, after which the chloroform extract was dried and reconstituted in methanol. GAs with 13:0, 15:1, and 17:1 in the extract were successfully separated within 40 min and determined with high throughput performance using an online column-switching HPLC method using an SP column C8 SG80 ($4.6{\times}150mm$, $5{\mu}m$) and a Cadenza 5CD C18 column ($4.6{\times}150mm$, $3{\mu}m$). The developed HPLC method was validated for Ginkgo biloba leaf extract. The validation parameters were specificity, linearity, precision, accuracy, and limits of detection and quantitation (LODs and LOQs, respectively). It was found that all of the calibration curves showed good linearity ($r^2$ > 0.9993) within the tested ranges. The LODs and LOQs were all lower than $0.04{\mu}g/mL$. The established method was found to be simple, rapid, and high throughput for the quantitative analysis of GAs in ten commercial Ginkgo biloba leaf extract and dietary supplements. The samples were also analyzed in LC-electrospray ionization (ESI) tandem mass spectrometry (MS/MS) - multiple-ion reaction monitoring (MRM) mode to confirm the identification results that were obtained by the column switching HPLC-DAD method. The developed method is considered to be suitable for the routine quality control and safety assurance of Ginkgo biloba leaf extract.

MS-Based Technologies for the Study of Site-Specific Glycosylation

  • Kim, Unyong;Oh, Myung Jin;Lee, Jua;Hwang, Hee Yeon;An, Hyun Joo
    • Mass Spectrometry Letters
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    • 제8권4호
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    • pp.69-78
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    • 2017
  • Glycosylation, which is one of the most common post-translation modification (PTMs) of proteins, plays a variety of crucial roles in many cellular events and biotherapeutics. Recent advances have led to the development of various analytical methods employing a mass spectrometry for glycomic and glycoproteomic study. However, site-specific glycosylation analysis is still a relatively new area with high potential for technologies and method development. This review will cover current MS-based workflows and technologies for site-specific mapping of glycosylation ranging from glycopeptide preparation to MS analysis. Bioinformatic tools for comprehensive analysis of glycoprotein with high-throughput manner will be also included.

고속광통신망용 새로운 WDM/TDM 프로토콜 (A new WDM/TDM protocol for very high speed optical networks)

  • 이상록;이성근;박진우
    • 전자공학회논문지A
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    • 제33A권2호
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    • pp.50-58
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    • 1996
  • This paper proposes the channel-access protocol suitable to a very high speed photonic WDM network with star configuration, which can provide a high channel utilization and insensitivity to the propagation delay. The proposed protocol employs a control channel and a simple status table to deal with the propagation delay which has been a major limiting factor in the performance of the very high speed optical communication networks. The control channel transmits control information in order to reserve access on data channels, and each node constitutes a status table after the reception of control pckets which holds information about the availbility of destination node and data channel. The proposed protocol is insensitive to the propagation delay time by removing necessity of the retransmission and by allowing parallel transmission of control packet and data packets. It is proved in analysis and discrete event simulation that the proposed protocol is superior in throughput and mean delay, especially at the high load conditions compared to the existing high speed channel-access protocols.

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Review of statistical methods for survival analysis using genomic data

  • Lee, Seungyeoun;Lim, Heeju
    • Genomics & Informatics
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    • 제17권4호
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    • pp.41.1-41.12
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    • 2019
  • Survival analysis mainly deals with the time to event, including death, onset of disease, and bankruptcy. The common characteristic of survival analysis is that it contains "censored" data, in which the time to event cannot be completely observed, but instead represents the lower bound of the time to event. Only the occurrence of either time to event or censoring time is observed. Many traditional statistical methods have been effectively used for analyzing survival data with censored observations. However, with the development of high-throughput technologies for producing "omics" data, more advanced statistical methods, such as regularization, should be required to construct the predictive survival model with high-dimensional genomic data. Furthermore, machine learning approaches have been adapted for survival analysis, to fit nonlinear and complex interaction effects between predictors, and achieve more accurate prediction of individual survival probability. Presently, since most clinicians and medical researchers can easily assess statistical programs for analyzing survival data, a review article is helpful for understanding statistical methods used in survival analysis. We review traditional survival methods and regularization methods, with various penalty functions, for the analysis of high-dimensional genomics, and describe machine learning techniques that have been adapted to survival analysis.

적응변조코딩 기법을 사용하는 무선 전송에서의 TCP 성능 분석 (TCP Performance Analysis in Wireless Transmission using Adaptive Modulation and Coding Schemes)

  • 전화숙;최계원;정동근
    • 한국정보과학회논문지:정보통신
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    • 제31권2호
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    • pp.188-195
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    • 2004
  • 본 논문에서는 적응변조코딩(Adaptive Modulation and Coding) 기법을 사용하는 CDMA 무선 통신 시스템에서의 TCP 성능을 분석한다. AMC를 사용하는 무선 채널은 패킷 손실 확률이 매우 낮고 대역폭이 시간에 따라 크게 변하는 특성을 갖는다. 무선채널 대역폭의 큰 변화 때문에 전송계층 프로토콜로 TCP를 사용하는 경우, TCP에서 timeout이 자주 발생하게 되어 결과적으로 시스템의 처리량(throughput)이 크게 떨어진다. 논문의 분석은 크게 두 부분으로 구성된다. 첫 번째 부분에서는 서버에서 전송되는 TCP 패킷들을 여러 집단으로 나누어 ‘패킷 그룹’이라 정의하고 각각의 패킷 그룹들이 AMC를 사용하는 무선 채널에서 전송되는 시간의 분포를 구하였다. 두 번째 부분에서는 첫 번째 부분의 결과를 토대로 embedded Markov chain을 이용해 TCP timer와 무선 전송을 모델링 하였다. 이 논문의 결과는 AMC를 사용하는 고속 순방향 데이타 전송 시스템인 HSDPA, 1xEV-DO, 1xEV-DV등의 설계와 운영에 지침이 될 수 있을 것이다.