• Title/Summary/Keyword: High risk factor

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Role of Electromagnetic Field Exposure in Childhood Acute Lymphoblastic Leukemia and No Impact of Urinary Alpha-Amylase - a Case Control Study in Tehran, Iran

  • Tabrizi, Maral Mazloomi;Hosseini, Seyed Ahmad
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7613-7618
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    • 2015
  • Childhood acute lymphoblastic leukemia (ALL) is one of the most common hematologic malignancies which accounts for one fourth of all childhood cancer cases. Exposure to environmental factors around the time of conception or pregnancy can increase the risk of ALL in the offspring. This study aimed to evaluate the influence of prenatal and postnatal exposure to high voltage power lines on the incidence of childhood ALL. It also examines the role of various factors such as environmental factors and alpha-amylase as a marker in the development of leukemia.This cross-sectional case control study was carried out on 22 cases and 100 controls who born and lived in low socioeconomic families in Tehran and were hospitalized for therapeutic purposes in different hospitals ofrom 2013-2014. With regard to the underlying risk factors; familial history and parental factors were detected as risk factors of ALL but in this age, socioeonomic and zonal matched case control study, prenatal and childhood exposure to high voltage power lines was considered as the most important environmental risk factor (p=0.006, OR=3.651, CI 95% 1.692-7.878). As the population study was from low socioeconomic state, use of mobiles, computers and microwaves was negligible. Moreover prenatal and postnatal exposure to all indoor electrically charged objects were not detected as significant environmental factors in the present study. This work defined the risk of environmental especially continuous pre and postnatal exposure to high voltage power lines and living in pollutant regions through the parents or children as well as the previously described risk factors of ALL for the first time in low socioeconomic status Iranian population.

Relation of serum total antioxidant status with metabolic risk factors in Korean adults

  • Kwak, Ho-Kyung;Yoon, Sun
    • Nutrition Research and Practice
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    • v.1 no.4
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    • pp.335-340
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    • 2007
  • The purpose of the present study was to examine the relation of total antioxidant status (TAS) to metabolic risk factors in Korean adults. Anthropometric measures, blood pressure, serum lipids and fasting glucose were determined in 406 men and women. TAS was measured by using commercially available Randox kit. Serum TAS was significantly positively correlated with body weight (p=0.004), body mass index (BMI) (p=0.033), waist circumference (p=0.017), total cholesterol (p=0.038) and triglyceride (TG) (p<0.001). The mean TAS of hypertriglyceridemic subjects (TG ${\geq}$150 mg/dl) was significantly higher than that of subjects whose TG was lower than 150 mg/dl (p=0.001). When central obesity, TG, high density lipoprotein cholesterol, fasting glucose and blood pressure were considered as metabolic risk factors, TAS was shown to be elevated with increased number of metabolic risk factors (p=0.004). The positive association between TAS and a number of metabolic risk factors suggests that increased TAS may not always indicate one's healthier condition. In order to help understand TAS as a marker of total antioxidant capacity in humans with various metabolic conditions, it is needed to clarify the factors affecting TAS in relation to changes in metabolic risk factors.

Comprehensive Investigation on the Prevalence and Risk Factors of Coexistence of Age-related Loss of Skeletal Mu scle Mass and Obesity among Males in Their 40s

  • Jongseok Hwang
    • Journal of the Korean Society of Physical Medicine
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    • v.18 no.3
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    • pp.1-9
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    • 2023
  • PURPOSE: This study examined the prevalence and specific risk factors in males aged 40-49 years with the coexistence of age-related loss of skeletal muscle mass and obesity (CALSMO). METHODS: The current study analyzed the data obtained from a cross-sectional study involving a sample of 1,218 men who resided in the community and fell within the age range of 40 to 49 years. Multiple risk factors were examined: age, height, weight, body mass index, waist circumference, skeletal muscle mass index, smoking and drinking habits, systolic and diastolic blood pressure, fasting glucose levels, and triglyceride and cholesterol levels. All data were analyzed via complex sampling analysis. RESULTS: The coexistence of age-related loss of skeletal muscle mass and obesity in males was 2.94% (95% CI: 2.06-4.17). The clinical risk factors were low height, high weight, body mass index, waist circumference, skeletal muscle index, systolic blood pressure, diastolic blood pressure, and fast glucose (p < .05). CONCLUSION: The study identifies the prevalence and risk factors for CALSMO among adults in the community. These findings contribute to the existing literature on CALSMO and highlight potential risk factors associated with CALSMO development in males aged 40-49 years.

Effect of Evaluation Response Spectrum on the Seismic Risk of Structure (평가용 스펙트럼이 구조물의 지진리스크에 미치는 영향)

  • Kim, Min-Kyu;Choi, In-Ki
    • Journal of the Earthquake Engineering Society of Korea
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    • v.13 no.6
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    • pp.39-46
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    • 2009
  • The selection of an evaluation response spectrum can have a significant effect on the seismic fragility evaluation of a structure. A method for modifying the seismic fragility parameters that are calculated based on the design spectrum is described in this study. The modification factor is used to modify the original fragility parameters. The HCLPF (High Confidence of Low Probability of Failure) acceleration levels of the electric system using previous design spectrum and uniform hazard spectrum (UHS) were compared. Finally, seismic risk analyses were performed according to a uniform hazard spectrum. From the results, it was concluded that based on the design spectrum, seismic risk for the electric system might be underestimated.

Clothing Expense, Consumer Innovativeness and Perceived Risk of Male and Female Customers of Various Fashion Retail Channels (주 이용 패션 소매 유통 경로에 따른 남녀 고객들의 의복 지출, 소비자 혁신성 및 구매 시 위험 지각 수준 비교)

  • Chung, Ihn Hee
    • Journal of the Korean Society of Clothing and Textiles
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    • v.39 no.5
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    • pp.714-727
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    • 2015
  • This study investigated consumers' clothing expense, consumer innovativeness and perceived risk to the channel type they frequently purchase fashion products and compared the relationship between the variables. A survey of male and female college students was conducted and 367 responses were analyzed using descriptive statistics, chi-square analysis, two-way ANOVA, factor analysis, reliability analysis, and correlations. Female consumer clothing expenses were high compared to male consumers, and clothing expenses of consumers using department stores and independent banded stores were high compared to those using internet shopping malls. The sub-dimensions of consumer innovativeness were determined as adventure-oriented, unique-oriented, and change-oriented, and female consumers have characteristics more unique-oriented and change-oriented. In the case of female respondents, unique-oriented innovativeness was highest for department store customers, while the male customer of non-branded stores showed the highest unique-oriented innovativeness. Perceived risk indicated the highest score from the customers of internet shopping mall. Department stores were recognized as reliable by female department store customers. Clothing expenses and consumer innovativeness dimensions showed significantly positive correlations; in addition, the relation between clothing expense and perceived risks were significantly negative. Consumer innovativeness and perceived risks have positive relations.

Cognitive Impairment and Risk Factors among Elderly Persons Aged 60 or More in Korea (한국의 60세 이상 노인의 인지장애와 위험요인)

  • Kim, Hye-Ryoung;Yang, Migyeong
    • Journal of Korean Public Health Nursing
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    • v.27 no.3
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    • pp.450-465
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    • 2013
  • Purpose: The purpose of this study was to identify cognitive impairment and risk factors among elderly persons aged 60 or more in Korea using raw data from the 2008 Elderly Survey: Basic Analysis Report of Actual Living Condition of the Elderly and Welfare Need Survey in Korea. Methods: This study was conducted using raw data obtained from 13,335 subjects representing elderly persons aged 60 or more in Korea. Data were analyzed using SPSS 19.0 software. Results: The rate of cognitive impairment was found to be 22.0%. Logistic regression analysis became more prevalent with increased aged. In addition elderly subjects with the following factors showed increased cognitive impairment: mails; underweight; slept well for 3 to 4 days per week at most; lack of high intensity physical activity; Eub/Myoun area; did not live alone; did not graduate from high school; un-employed; lack of active social participation, and not computer/Internet savvy. Conclusion: This study identified cognitive impairment and risk factors among elderly persons aged 60 or more in Korea using samples representing elderly persons aged 60 or more throughout the country.

Risk Factors of Malnutrition by Age in Hospitalized Older Adults (입원 노인의 연령별 영양불량 위험요인)

  • Kim, Eun Jung
    • Journal of Korean Clinical Nursing Research
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    • v.27 no.1
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    • pp.77-84
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    • 2021
  • Purpose: Malnutrition affects all age groups, but older adults are particularly more vulnerable to nutritional deficiencies. This study evaluated the age-specific factors affecting malnutrition in hospitalized older adults. Methods: A retrospective study was conducted on inpatient elderly people who received artificial nutrition from 2010 to 2017. Data of demographics, diagnosis, type of nutrition therapy, number of comorbidity, fall risk assessment, Acute Physiologic Assessment and Chronic Health Evaluation (APACHE) score, and intensive care unit admission were collected. Malnutrition was defined as a body mass index (BMI) of less than 18.5 kg/m2. Patients were classified as the young-old (65~74 years old), the old-old (75~84 years old), or the oldest-old (85 years old or older). Results: A total of 7,130 older adults were included, and 4,028 patients were classified as the young-old, 2,506 into the old-old, and 596 into the oldest-old. Proportion of malnutrition was higher in the oldest-old compared to the other groups. In multivariate analysis, parenteral nutrition, alcohol, and high risk of falls were factors affecting malnutrition in all groups. Parenteral nutrition and alcohol in the young-old, high risk of falls in the old-old, and male sex in the oldest-old were the factors affecting malnutrition by the age group. Conclusion: Older age was the most significant factor affecting malnutrition. Specific strategies by age are needed to improve nutritional status in hospitalized older adults as influencing factors for malnutrition vary among different age groups.

A Study on the Influence Factors for Virtual Enterprise (가상기업의 성과요인에 관한 연구)

  • Park, Kyung-Hye;Choi, Se-Yeon
    • Journal of Information Technology Applications and Management
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    • v.14 no.1
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    • pp.117-135
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    • 2007
  • Globalization changes in market structures and consumer needs, as well as technology innovations force organizations to adopt new structures and collaborative networks to cope with rapidly changing environments. These Collaborative Networks are based on the Idea of virtual enterprise. A virtual enterprise(VE) is a temporary alliance of globally distributed independent enterprises that share core competencies and computer networks. This paper presents a proposal for a methodology to measure a key factor of success and risk First of all, we chose thirty experts' defines on virtual enterprise, fifteen are academic specialist and other fifteen are from industry. For this study we define twenty two factors determining VE's success and seventeen factors determining VE's risk using by Delphi method. And we built the influence model on virtual enterprise. A research model was established according to preceeding research and consensus on experts then the revised model of key factors on virtual enterprise. This survey was based on the Analytical Hierarchy Process (AHP). AHP is an approach to decision making that involves structuring multiple choice criteria into a hierarchy, the assessing the relative important of these criteria, comparing alternative for each criteria, and determining an overall ranking of the alternatives. A model was constructed as 3 level hierarchy. The hierarches are organizational, strategic, technical criteria. for success model on VE has 22 factors and 17 factors for risk model. They are selected by all 30 experts. 14 copies among 30 copies distributed to carry out on the Analytical Hierarchy Process (AHP). Consistency ratio confirm high validity and reliability of instrument and support theoretical model. The results of this study are summarized as follows. (1) This study presented success on VE influenced strategic criteria, and essential factor is Creating a value. Risk on VE influenced strategic criteria, and essential factor is Outcome/Distribution. (2) Its enable that ranking the criteria influence on VE. These are supported VE management and using guideline of VE.

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Vitamin D deficiency is an independent risk factor for cardiovascular disease in Koreans aged ${\geq}50$ years: results from the Korean National Health and Nutrition Examination Survey

  • Park, Sun-Min;Lee, Byung-Kook
    • Nutrition Research and Practice
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    • v.6 no.2
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    • pp.162-168
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    • 2012
  • Vitamin D deficiency is a risk factor for metabolic syndromes. We examined whether vitamin D deficiency altered the prevalence of cardiovascular disease (CVD) in older Koreans. Cross-sectional analysis of data from the Korean National Health and Nutrition Examination Survey IV 2008-2009 was used to examine the association between serum 25-hydroxyvitamin D (25(OH)D) levels and the prevalence of CVD in a representative population-based sample of 5,559 men and women aged ${\geq}50$ years. CVD was defined as angina pectoris, myocardial infarction, or stroke. The prevalence of CVD (7.0%) in the older Korean population was lower than that in the older US population, although average serum 25(OH)D levels were much lower in the Korean population. Additionally, serum 25(OH)D levels did not differ significantly between the CVD and non-CVD groups. However, subjects in the lowest category (< 25 nmol/l) of serum 25(OH)D level had the greatest prevalence of CVD, about two-fold higher than subjects in the highest category (> 75 nmol/l), after adjusting for age, gender, body mass index, education level, residence location, and region. The prevalence of other risk factors for CVD, including higher waist circumference, fasting glucose, low-density lipoprotein (LDL) cholesterol, and triglyceride levels and lower high-density lipoprotein (HDL) cholesterol levels, was also higher among subjects in the lowest category than among those in the highest category. In conclusion, low serum 25(OH)D may be an independent risk factor for CVD in older Koreans.

Early dropout predictive factors in obesity treatment

  • Michelini, Ilaria;Falchi, Anna Giulia;Muggia, Chiara;Grecchi, Ilaria;Montagna, Elisabetta;De Silvestri, Annalisa;Tinelli, Carmine
    • Nutrition Research and Practice
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    • v.8 no.1
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    • pp.94-102
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    • 2014
  • Diet attrition and failure of long term treatment are very frequent in obese patients. This study aimed to identify pre-treatment variables determining dropout and to customise the characteristics of those most likely to abandon the program before treatment, thus making it possible to modify the therapy to increase compliance. A total of 146 outpatients were consecutively enrolled; 73 patients followed a prescriptive diet while 73 followed a novel brief group Cognitive Behavioural Treatment (CBT) in addition to prescriptive diet. The two interventions lasted for six months. Anthropometric, demographic, psychological parameters and feeding behaviour were assessed, the last two with the Italian instrument VCAO Ansisa; than, a semi-structured interview was performed on motivation to lose weight. To identify the baseline dropout risk factors among these parameters, univariate and multivariate logistic models were used. Comparison of the results in the two different treatments showed a higher attrition rate in CBT group, despite no statistically significant difference between the two treatment arms (P = 0.127). Dropout patients did not differ significantly from those who did not dropout with regards to sex, age, Body Mass Index (BMI), history of cycling, education, work and marriage. Regardless of weight loss, the most important factor that determines the dropout appears to be a high level of stress revealed by General Health Questionnaire-28 items (GHQ-28) score within VCAO test. The identification of hindering factors during the assessment is fundamental to reduce the dropout risk. For subjects at risk, it would be useful to dedicate a stress management program before beginning a dietary restriction.