• 제목/요약/키워드: High control margin

검색결과 152건 처리시간 0.031초

근칙적 절제술과 술후 방사선치료를 시행한 자궁경부암 환자의 치료성적, 예루인자와 실패양상 (Adjuvant Radiotherapy Following Radical Hysterectomy and Bilateral Pelvic Lymph Node Dissection for the Uterine Cervical Cancer : Prognostic Factors and Failure Patterns)

  • 최두호
    • Radiation Oncology Journal
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    • 제15권4호
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    • pp.357-367
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    • 1997
  • 목적 : 근치적 절제술과 골반림프절 절제술을 시행한 자궁경부암 환자 중에서 치료실패의 위험인자가 있어서 술후 방사선치료를 시행한 환자를 대상으로 치료성적, 예후인자, 실패양상을 알아보기 위하여 후향적 분석을 시행하였다. 대상 및 방법 : FIGO 병기 IB, IIA와 IIB 환자 중에서 근치적 수술과 방사선치료를 시행하고 추적조사가 가능하였던 124명을 대상으로 하였다. 환자들은 1985년 3월부터 1994년 3원까지 수술후 방사선치료를 시행하였으며 최소 추적기간은 24개월이었다. 모든 환자는 4-MV 선형가속기를 이용한 외부방사선치료를 전골반에 50-6OGy를 조사하였고 일부 환자는 코발트를 이용한 고선량율 강내치료를 추가하였다. 결과 : 전체 환자의 5년 생존율과 5년 무병 생존율은 각각 $75.4\%,\;73.5\%$였고, 단변수 분석상 5년 무병 생존율에 영향을 미치는 인자는 림프절 전이 유무, 개수와 위치, 종양의 크기, 자궁체부 침운, 자궁주위조직 침윤, 병기, 자궁경부벽 침윤정도, 질 절제면 양성, 그리고 치료 관계 인자로 방사선량, 강내치료, 항암제 등이 통계상 유의하였으며, 다변량 분석상 림프절 전이와 종양의 크기, 질 절제면 양성이 유의하였다. 치료 실패는 33명이었고 2명은 다른 원인으로 사망하였고 부위별로는 국소재발이 13명, 원격전이 13명 국소-원격 동시 실패가 7명이었고 추적 종료시점까지 5명이 생존하였다. 국소재발은 병기 IB, 림프절 전이 양성 또는 질 절제면 양성 환자에서 많이 발생하였으며 림프절 전이 음성환자에서는 빈도는 낮았으나 원격전이가 상대적으로 더 많았다. 그리고 병기 lIB에서 5년 생존율 은 $56\%$ 였고 22명 중에서 9명이 재발하였다. 결론 : 수술후 방사선치료는 비교적 효과적인 방법이지만 다수의 재발 위험인자들을 가진 환자에게 술후 방사선치료만으로는 재발을 막기가 충분하지 않으므로 방사선감작제의 추가나 동시방사선-항암치료 등의 보다 효과적인 방법이 필요할 것으로 성각되며, 술혹 방사선치료의 효율을 정하기 위하여 무작위 표본 추출에 의한 전향적 연구가 필오하다. 그리고 병기 IIB는 항암치료와 수술후 방사선치료를 시행해도 치료 성적이 나쁘므로 일차적으로 근치적 방사선치료를 시행해야한다.

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Korea Total Diet Study-Based Risk Assessment on Contaminants Formed During Manufacture, Preparation and Storage of Food

  • Kwon, Kisung;Jo, Cheon-Ho;Choi, Jang-Duck
    • 한국식품위생안전성학회지
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    • 제36권3호
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    • pp.213-219
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    • 2021
  • 식품의 제조, 가공, 조리 및 저장 중 많은 유해물질이 발생하며 이들은 소량이지만 장기간 노출되면 식품안전에 위협이 될 수 있다. 본 연구에서는 식품의약품안전처에서 수행한 총 식이조사(TDS) 자료를 기반으로 우리나라에서 식품섭취를 통한 이들 주요 유해물질에 대한 노출 및 위해평가 상황을 파악하고 소비자 및 기업으로 하여금 관련 위험을 저감하는 방안을 제시하고자 하는 것이다. 식품의 제조, 가공, 조리 및 저장 중 생성 유해물질 중 대표적인 아크릴아미드, 퓨란, 에틸 카바메이트, 3-MCPD, 바이오제닉 아민류, 니트로아민류 화합물, 다환 방향족화합물, 벤젠 등에 대한 식이를 통한 노출량을 조사하고 위해평가를 수행한 바, 아크릴아미드 및 퓨란의 경우 노출안전역(MOE) 10,000이하로 저감화 우선 물질로 판단되며, 나머지 물질 등의 경우 모두 노출안전역이 10,000 또는 100,000 이상으로 안전한 수준에 있는 것으로 나타났음. 그러나 향후 지속적으로 모니터링을 수행하고 ALARA 원칙에 따라 가능한 노출 저감화를 위해 노력을 기울여야한다.

HTGR PROJECTS IN CHINA

  • Wu, Zongxin;Yu, Suyuan
    • Nuclear Engineering and Technology
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    • 제39권2호
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    • pp.103-110
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    • 2007
  • The High Temperature Gas-cooled Reactor (HTGR) possesses inherent safety features and is recognized as a representative advanced nuclear system for the future. Based on the success of the HTR-10, the long-time operation test and safety demonstration tests were carried out. The long-time operation test verifies that the operation procedure and control method are appropriate for the HTR-10 and the safety demonstration test shows that the HTR-10 possesses inherent safety features with a great margin. Meanwhile, two new projects have been recently launched to further develop HTGR technology. One is a prototype modular plant, denoted as HTR-PM, to demonstrate the commercial capability of the HTGR power plant. The HTR-PM is designed as $2{\times}250$ MWt, pebble bed core with a steam turbine generator that serves as an energy conversion system. The other is a gas turbine generator system coupled with the HTR-10, denoted as HTR-10GT, built to demonstrate the feasibility of the HTGR gas turbine technology. The gas turbine generator system is designed in a single shaft configuration supported by active magnetic bearings (AMB). The HTR-10GT project is now in the stage of engineering design and component fabrication. R&D on the helium turbocompressor, a key component, and the key technology of AMB are in progress.

10년 관찰기간 중 다수의 국소 재발을 보인 설암 환자 (Locoregional Recurrence of a Tongue Cancer Patient with 10 Year Follow-up)

  • 송재민;이성탁;이주민;송원욱;김용덕;김욱규
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제35권6호
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    • pp.390-395
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    • 2013
  • Locoregional recurrence of tongue cancer is higher than that of other sites of the oral cavity. Locoregional control has shown improvement over the past 20 years, however, a high rate of recurrence and second primary tumor occurrence is still frequently reported. Leukoplakia is a clinical term, which describes a whitish lesion of the oral cavity. Clinicopathologic features may range from hyperkeratosis to malignancy. Because of its diverse pathologic characteristics, management of this lesion for diagnosis, treatment planning, establishment of a clear surgical margin, and periodic follow-up is difficult. We report on a case of successfully treated tongue cancer which developed from leukoplakia over 10 years. Periodic follow-up strategy and surgical planning are most important to management of locoregional recurrence.

가변 디퓨저를 장착한 원심 압축기 불안정성 연구 (A Study on the Instabilities of the Centrifugal Compressor with Variable Diffuser)

  • 차봉준;임병준;양수석
    • 대한기계학회논문집B
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    • 제26권8호
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    • pp.1123-1131
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    • 2002
  • An experimental study on the performance and instability development characteristics of a centrifugal compressor equipped with a cambered variable diffuser has been performed with varying diffuser vane angles. The test was conducted at the design speed of 20,800 rpm and the 80% design speed of 16,640 rpm for 5 diffuser angles : 65$^{\circ}$, 70$^{\circ}$, 75$^{\circ}$, 77.5$^{\circ}$, 80$^{\circ}$ The steady performance test results showed that choking mass flow rate decreases and total pressure ratio increases with a narrowed surge margin as the diffuser vane angle increases. Unsteady pressures were measured using high-frequency pressure transducers at the inducer and the diffuser throat to investigate the instability phenomena such as rotating stall and surge inside the compressor. From the unsteady measurements, it is found that the transient process from rotating stall to surge was mainly affected by diffuser angles. The results of the present study can be applied to the instability control of the centrifugal compressors using a variable diffuser.

IoT Compliant HD Digital Signage Controller Design using Raspberry Pi

  • 양승연;신재권;이성화;김진태
    • 한국위성정보통신학회논문지
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    • 제12권1호
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    • pp.18-21
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    • 2017
  • In this paper we present IoT compliant HD Digital Signage Controller design using Raspberry Pi. Nowadays, the digital signage system have gained increasing popularity and rapidly growing communications medium that offers a wide range of exciting ways with customers, enhance brand awareness, increase sales and margin uplift by replacing the traditional static signage system. This paper presents a cost-effective IoT based HD Digital Signage Controller (DSC) using R-Pi computer that can use various kinds of displays in order to make the system as efficient and affordable as possible to provide advertisement or other relevant information to people in public areas. The system is designed in such way the information about surrounding related place is taken through sensors and directly uploaded to the internet, and thus can be accessed anytime and displayed on screens by using Raspberry Pi that serves as controller in the system. The design and implementation of the system developed by using python programming language and its hardware consists of sensors, Arduino, Raspberry Pi 3 model B board and the displays. The main targets of this study are build a cost effective Digital Signage system as well as broadcasting information at display contents in public areas and control those digital signs.

선체의 태양복사 열변형 해석을 위한 전처리시스템 (A System for Thermal Distortion Analysis of Hull Structures by Solar Radiation)

  • 하윤석;이동훈
    • 대한조선학회논문집
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    • 제53권4호
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    • pp.275-281
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    • 2016
  • One of the most important things for quality to meet ship-production schedule is an accuracy control. A ship is assembled by welding through whole production process, so it is important that loss by correction will not happen as much as possible by using some engineering skills like reverse design, reverse setting and margin for thermal shrinkage. These efforts are a quite effective in fabrication stages, but not in erection stages. If a ship block which consists of common steel is exposed to directional solar radiation, its dimensional accuracy will change high as time by its thermal expansion coefficient. Therefore, the measuring work would be often done at dawn or evening even with having a very accurate device. In this study, an FE analysis method is developed to solve this problem. It can change measured data affected by solar thermal distortion to ones not, even though ship-block is measured at an arbitrary time. It will use the time when measuring, the direction of block and the weather record by satellites. It is confirmed by a comparison between measured data of a ship-block and the result by suggested analysis method. Furthermore, a pre-processing system is also developed for fast application of the suggested analysis method.

Effect of Rumen Protected Methionine on Lactational Performance of Dairy Cows

  • Izumi, K.;Kikuchi, C.;Okamoto, M.
    • Asian-Australasian Journal of Animal Sciences
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    • 제13권9호
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    • pp.1235-1238
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    • 2000
  • Thirty-six Holstein dairy cows were used to evaluate the effect of a rumen protected methionine supplement (RPMet). The cows were divided into two groups of 18 each (control/experimental). The experimental group was given 15 g/d of RPMet (Mepron $^{(R)}$M85, Degussa) from the 4th to the 26th week postpartum. All cows were fed a similar amount of forage including alfalfa silage, corn silage and timothy silage. Concentrate mixture was offered in proportion to the milk yield of each cow. Sufficiency of major metabolizable AAs was checked. Milk yield and milk composition was monitored for each individual cow. A metabolic profile test (MPT) was carried out at the 7th, 11th and 21st week postpartum. Without supplement, both methionine and leucine fell short of the daily requirement. Supplementation with 15 g/d RPMet was calculated to be within a sufficient margin of safety. Milk yield tended to remain higher in the supplemented group than in the controls during supplementation with RPMet. The differences in weekly milk production at the 17th, 18th, 19th and 22nd weeks postpartum were significantly high in the RPMet group (p<0.05). The average 305-d milk yield and the percentages of milk fat, milk protein and solids-not-fat were not affected by the treatment. No differences were observed in either the somatic cell count in the milk or the reproductive status. Judging from MPT, all the cows were in good health during lactation.

Hardware-Based Implementation of a PIDR Controller for Single-Phase Power Factor Correction

  • Le, Dinh Vuong;Park, Sang-Min;Yu, In-Keun;Park, Minwon
    • 한국산업정보학회논문지
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    • 제21권4호
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    • pp.21-30
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    • 2016
  • In a single-phase power factor correction (PFC), the standard cascaded control algorithm using a proportional-integral-derivative (PID) controller has two main drawbacks: an inability to track sinusoidal current reference and low harmonic compensation capability. These drawbacks cause poor power factor and high harmonics in grid current. To improve these drawbacks, this paper uses a proportional-integral-derivative-resonant (PIDR) controller which combines a type-III PID with proportional-resonant (PR) controllers in the PFC. Based on a small signal model of the PFC, the type-III PID controller was implemented taking into account the bandwidth and phase margin of the PFC system. To adopt the PR controllers, the spectrum of inductor current of the PFC was analyzed in frequency domain. The hybrid PIDR controller were simulated using PSCAD/EMTDC and implemented on a 3 kW PFC prototype hardware. The performance results of the hybrid PIDR controller were compared with those of an individual type-III PID controller. Both controllers were implemented successfully in the single-phase PFC. The total harmonic distortion of the proposed controller were much better than those of the individual type-III PID controller.

양방향성 PWM컨버터를 이용한 가정용 태양광 에어컨 시스템에 관한 연구 (A study of residential solar airconditioning system using bidirectional PWM converter)

  • 유권종;송진수;황인호;김홍성;고재석;최규하;김한성
    • 대한전기학회논문지
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    • 제45권3호
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    • pp.358-364
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    • 1996
  • Recently, much power demand from domestic power consumer is weakening the allowable power reserve margin in summer, especially at midday for one day due to a steep increase of air cooling loads such as air conditioner. Therefore solar airconditioning system can'be considered as one of the best remedies to meet the increase of peak power. Generally in solar air conditioning system, the diode rectifier is used to build up DC link voltage from AC source. The diode rectifier is simple and cheap but it brings out the problems of low power factor and plentiful harmonics at the AC source. Also It can derate the utilization rate of solar energy because the reverse of power flow cannot be made. Hence, in this paper to overcome the peak power problem in summer and to endure good AC input characteristics, solar air conditioning system using the PWM converter is proposed. As results, obtained are the characteristics of the PWM converter such as low distorted current waveform, high power factor and bidirectional power control. And also the stability of proposed system is verified by examining the dynamics of step load change and power reversal testing. (author). refs., figs., tabs.

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