DOI QR코드

DOI QR Code

Locoregional Recurrence of a Tongue Cancer Patient with 10 Year Follow-up

10년 관찰기간 중 다수의 국소 재발을 보인 설암 환자

  • Song, Jae-Min (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University) ;
  • Lee, Sung-Tak (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University) ;
  • Lee, Ju-Min (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University) ;
  • Song, Won-Wook (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University) ;
  • Kim, Yong-Deok (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University) ;
  • Kim, Uk-Kyu (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University)
  • 송재민 (부산대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 이성탁 (부산대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 이주민 (부산대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 송원욱 (부산대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 김용덕 (부산대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 김욱규 (부산대학교 치의학전문대학원 구강악안면외과학교실)
  • Received : 2013.02.22
  • Accepted : 2013.11.28
  • Published : 2013.11.30

Abstract

Locoregional recurrence of tongue cancer is higher than that of other sites of the oral cavity. Locoregional control has shown improvement over the past 20 years, however, a high rate of recurrence and second primary tumor occurrence is still frequently reported. Leukoplakia is a clinical term, which describes a whitish lesion of the oral cavity. Clinicopathologic features may range from hyperkeratosis to malignancy. Because of its diverse pathologic characteristics, management of this lesion for diagnosis, treatment planning, establishment of a clear surgical margin, and periodic follow-up is difficult. We report on a case of successfully treated tongue cancer which developed from leukoplakia over 10 years. Periodic follow-up strategy and surgical planning are most important to management of locoregional recurrence.

Keywords

References

  1. Sun JR, Kim SM, Seo MH, Kim MJ, Lee JH, Myoung H. Oral cancer incidence based on annual cancer statistics in Korea. J Korean Assoc Oral Maxillofac Surg 2012;38:20-8. https://doi.org/10.5125/jkaoms.2012.38.1.20
  2. Franceschi D, Gupta R, Spiro RH, Shah JP. Improved survival in the treatment of squamous carcinoma of the oral tongue. Am J Surg 1993;166:360-5. https://doi.org/10.1016/S0002-9610(05)80333-2
  3. Kirita T, Okabe S, Izumo T, Sugimura M. Risk factors for the postoperative local recurrence of tongue carcinoma. J Oral Maxillofac Surg 1994;52:149-54. https://doi.org/10.1016/0278-2391(94)90398-0
  4. Sarkaria JN, Harari PM. Oral tongue cancer in young adults less than 40 years of age: rationale for aggressive therapy. Head Neck 1994;16:107-11. https://doi.org/10.1002/hed.2880160202
  5. Silverman S Jr, Gorsky M, Lozada F. Oral leukoplakia and malignant transformation. A follow-up study of 257 patients. Cancer 1984;53:563-8. https://doi.org/10.1002/1097-0142(19840201)53:3<563::AID-CNCR2820530332>3.0.CO;2-F
  6. Banoczy J. Follow-up studies in oral leukoplakia. J Maxillofac Surg 1977;5:69-75. https://doi.org/10.1016/S0301-0503(77)80079-9
  7. Saito T, Sugiura C, Hirai A, et al. Development of squamous cell carcinoma from pre-existent oral leukoplakia: with respect to treatment modality. Int J Oral Maxillofac Surg 2001;30:49-53. https://doi.org/10.1054/ijom.2000.0012
  8. Schepman KP, van der Meij EH, Smeele LE, van der Waal I. Malignant transformation of oral leukoplakia: a follow-up study of a hospital-based population of 166 patients with oral leukoplakia from The Netherlands. Oral Oncol 1998;34: 270-5. https://doi.org/10.1016/S1368-8375(98)80007-9
  9. Yang SW, Tsai CN, Lee YS, Chen TA. Treatment outcome of dysplastic oral leukoplakia with carbon dioxide laser--emphasis on the factors affecting recurrence. J Oral Maxillofac Surg 2011;69:e78-87.
  10. Frame JW. The management of oral premalignant lesions. Br J Oral Maxillofac Surg 1992;30:71. https://doi.org/10.1016/0266-4356(92)90072-Q
  11. Pignon JP, Bourhis J, Domenge C, Designe L. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer. Lancet 2000;355:949-55. https://doi.org/10.1016/S0140-6736(00)90011-4
  12. Po Wing Yuen A, Lam KY, Lam LK, et al. Prognostic factors of clinically stage I and II oral tongue carcinoma-A comparative study of stage, thickness, shape, growth pattern, invasive front malignancy grading, Martinez-Gimeno score, and pathologic features. Head Neck 2002;24:513-20. https://doi.org/10.1002/hed.10094
  13. Spiro RH, Huvos AG, Wong GY, Spiro JD, Gnecco CA, Strong EW. Predictive value of tumor thickness in squamous carcinoma confined to the tongue and floor of the mouth. Am J Surg 1986;152:345-50. https://doi.org/10.1016/0002-9610(86)90302-8
  14. Asakage T, Yokose T, Mukai K, et al. Tumor thickness predicts cervical metastasis in patients with stage I/II carcinoma of the tongue. Cancer 1998;82:1443-8. https://doi.org/10.1002/(SICI)1097-0142(19980415)82:8<1443::AID-CNCR2>3.0.CO;2-A
  15. Kaya S, Yilmaz T, Gürsel B, Sarac S, Sennaroglu L. The value of elective neck dissection in treatment of cancer of the tongue. Am J Otolaryngol 2001;22:59-64. https://doi.org/10.1053/ajot.2001.20681
  16. Mashberg A. Tolonium (toluidine blue) rinse--a screening method for recognition of squamous carcinoma. Continuing study of oral cancer IV. JAMA 1981;245:2408-10. https://doi.org/10.1001/jama.1981.03310480024019
  17. Iwai H, Kyomoto R, Ha-Kawa SK, Lee S, Yamashita T. Magnetic resonance determination of tumor thickness as predictive factor of cervical metastasis in oral tongue carcinoma. Laryngoscope 2002;112:457-61. https://doi.org/10.1097/00005537-200203000-00010
  18. Preda L, Chiesa F, Calabrese L, et al. Relationship between histologic thickness of tongue carcinoma and thickness estimated from preoperative MRI. Eur Radiol 2006;16:2242-8. https://doi.org/10.1007/s00330-006-0263-9
  19. Slaughter DP, Southwick HW, Smejkal W. Field cancerization in oral stratified squamous epithelium. Clinical implications of multicentric origin. Cancer 1953;6:963-8. https://doi.org/10.1002/1097-0142(195309)6:5<963::AID-CNCR2820060515>3.0.CO;2-Q
  20. Tabor MP, Brakenhoff RH, van Houten VM, et al. Persistence of genetically altered fields in head and neck cancer patients: biological and clinical implications. Clin Cancer Res 2001;7: 1523-32.