• 한국임상수의학회지
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• 제17권2호
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• pp.359-367
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• 2000

The aim of this study was to evaluate the effects of propofol on cortical electroencephalogram (EEG) in seven dogs. Propofol infusion was accomplished from low concentration to high concentration in series, and each concentration was infused for 20 minutes (M0: 0, M0.5: 0.5, M1.0:1.0, and M1.5: 1.5 mg/kg/min of infusion rate). EEG was recorded via needle electrode placed at Cz, which was applied to International 10-20 system. Arterial blood pressure. blood gas analysis and ECG were also measured. Hoemodynamics, Pa$CO_2$, PaO$_2$, heart rate and respiratory rate were variable, but were net significant(p>0.05). The power spectra of EEG in every concentration was compared wish those of control (MO). The powers at a1l frequencies at M1.0 and Ml.5 were decreased. Especially, the powers of the frequencies over 20 Hz were significantly decreased (p<0.O5). Powers at frequencies between 8 and 15Hz at MO.S were significantly increased (p<0.05) in response to the painful stimuli. It was inferred that they may reflect activity of the brain which is consciously processing the external Stimuli. Like the Power spectra, al1 the band powers of He EEG ($\delta$ 1-4, $\theta$4-8, $\alpha$ 8-13, $\beta$L13-21. $\beta$H 21-30, \ulcorner 30-50, and total 1-5OHz) were decreased in proportion to the increase of infusion rate at M1 .0 and M1.5. Especially, decrease of $\beta$H and ${\gamma}$ were significant(p<0.01). At M0.5, $\alpha$ band was significantly increased(p<0.05) among all the bands. Seizure activities which were concide with occurrence of spike wave were shown in all dogs at Ml .0 and M1.5.

• 대한토목학회논문집
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• 제12권3호
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• pp.221-229
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• 1992

퇴적물(堆積物)의 형태(形態), 함수비(含水比) 및 저면전단응력(底面剪斷應力)(${\tau}_b$)이 미세퇴적물(微細堆積物)의 부상특성(浮上特性)에 미치는 영향을 연구하기 위해 순환식 개수로에서 부상실험(浮上實驗)을 하였다. 시료는 한국(韓國)의 서해안(西海岸)에 위치한 영광해역과 남동해안(南東海岸)에 위치한 영도해역에서 채취한 것을 사용하였다. 퇴적물(堆積物)의 종류 및 함수비의 크기에 따른 부상한계저면전단응력(浮上限界底面剪斷應力)(${\tau}_c$)이 유추되었다. 동일한 시료에 대해서 함수비(含水比)가 클 수록 상한계저면전단응력(浮上限界底面剪斷應力)은 감소하였으나, 부상량(浮上量)은 증가하였다. 퇴적물(堆積物)의 부상(浮上)은 퇴적물(堆積物)의 함수량(含水量)에도 크게 좌우되지만, 입자간(粒子間)의 결합력(結合力)(점참력(粘着力))을 특징짓는 퇴적물(堆積物)의 형태(形態)에도 강하게 지배되었다. 한 방향 흐름장에서 부상한계저면전단응력(浮上限界底面剪斷應力)은 파-흐름 공존장에서의 부상한계저면전단응력(浮上限界底面剪斷應力)보다 약 4배 이상 크게 나타났다. 저면전단응력(底面剪斷應力)이 작을 경우에는 실험초기(實驗初期)에 급부상(急浮上)한 후 시간이 경과할 수록 저면의 경화로 인해 부상량(浮上量) 어느 일정치에 가까와지고 있으나, 저면전단응력(底面剪斷應力)이 클 수록 시간의 경과에 따라 저변의 연약화로 인해 부상량(浮上量)도 계속적으로 증가하였다. 각(各) 실험(實驗)에 대한 초기(初期) 부하율(浮上率) $E={\alpha}_3({\tau}_b/{\tau}_c-1)^{\beta}$ (${\alpha}_3$, ${\beta}$ = 경험적 상수)을 평가하였으며, 동일한 시료에 대해서는 함수비(含水比)가 클 수록 ${\alpha}_3$와 ${\beta}$ 값이 증가하였다.

• 감성과학
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• 제16권3호
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• pp.387-396
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• 2013

남자고등학교 교실에서 발생하는 냄새(발냄새, 머리냄새, 쉰냄새, 땀냄새)와 대표악취물질(부티르산, 암모니아)에 대한 뇌파반응을 분석하였다. 냄새자극 시험은 30~50대의 여성을 대상으로 수행하였다. 교실냄새와 대표악취물질의 자극에 대한 뇌파 지표들의 변화 경향은 측두엽에서 가장 두드러지게 나타났다. 이들 악취물질의 측두엽에서 반응은 바탕뇌파대비 상대알파파를 0.04~0.13 감소시켰고, 상대베타파 0.02~0.06, 상대감마파를 0.03~0.09 증가시켰다. 교실냄새들과 두 악취물질들은 이완상태를 나타내는 알파파를 감소시켰고, 각성과 긴장 및 스트레스를 나타내는 고베타파(18~30Hz)와 불안과 흥분상태를 나타내는 감마파(30~50Hz)를 활성화시켰다. 냄새물질들의 뇌 각성 및 자극정도는 머리냄새 > 부트르산 > 발냄새, 쉰냄새 > 암모니아> 땀냄새 순이었다. 이러한 결과는 교실냄새가 과도한 각성이나 긴장을 유발하므로 수업 집중력이나 학습능력을 저해할 수 있음을 의미한다.

• 농촌의학ㆍ지역보건
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• 제36권2호
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• pp.101-112
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• 2011

50세 이상 건강한 성인을 대상으로 baPWV로 측정한 동맥경직도 수준과 염증인자와 동맥경직도와의 관련성을 파악하기 위하여 본 연구를 수행하였다. 2007년과 2008년에 수행된 광주광역시 동구연구(Dong-gu Study)의 기반조사에 참여한 50세 이상 주민 4617명을 대상으로 하였으며, 다중회귀분석을 시행하여 전통적인 심뇌혈관질환 위험요인을 통제한 상태에서 baPWV와 CRP, GGT와 WBC 등의 염증반응인자와의 관련성을 알아보았다. 평균 baPWV는 남자 $17.0{\pm}4.0\;m/s$, 여자 $16.2{\pm}3.6\;m/s$로 남, 여 간에 통계적으로 유의한 차이가 있었고, 연령이 증가할수록 baPWV는 통계적으로 유의하게 증가하는 경향을 보였다. 성, 연령, 흡연상태, 체질량지수, 수축기혈압, 공복혈당, 고혈압 또는 당뇨병의 투약 여부, 혈청 지질, 요산과 ALT 등의 전통적인 심뇌혈관질환 위험요인을 통제한 상태에서 WBC (${\beta}$=0.158, p<0.0001), hs-CRP(${\beta}$=0.244, p=0.026)와 GGT (${\beta}$=0.003, p<0.0001)는 baPWV와 통계적으로 유의하게 독립적인 관련성이 있음을 알 수 있었다. 결론적으로 baPWV로 측정한 동맥경직도 지표는 염증반응인자와 관련이 있음을 알 수 있었다. baPWV 등의 동맥경직도 측정 지표는 동맥 기능의 초기변화를 반영하고 일반적으로 알려져 있는 심혈관질환 위험요인과 유의한 상관관계를 가지고 있어, 이를 이용하여 심혈관질환의 위험을 예측하는데 활용할 수 있을 것으로 생각된다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 춘계학술대회 논문집
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• pp.1918-1920
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• 2005

The color and structure of urban constructions is a factor of urban landscape and shows their characteristics. Hence the modern buildings with their materials and external appearance makes up the urban image. But still yet, it was not easy to evaluate the value of visual landscape of buildings with objective measuring method. Most of all, it depends on the subjective estimation of a few talented or high educated experts with a sense of beauty. In relation to this kind of problems, it was tried here in this study to analyse the human response of brain wave pattern (EEG) with use of SD method, while the tested persons watched the urban landscape constructed in a visual reality. The tested persons were 10 adult males and females with no color blindness and intact cognitive function. Light source with color filter was used for color environment in chamber room. The signal of EEG is analysed digitally and grouped into the $\alpha$ and $\beta$ waves. The result showed that relative power of $\alpha$ wave ratio increased in natural landscape scenary clearly. From these results it was possible to evaluate the human response, which was affected by urban color and structure stimulation and it might be useful as an indicator of visual cognition amenity toward the design of urban construction environment.

• 한국산학기술학회논문지
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• 제18권11호
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• pp.166-175
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• 2017

이 연구는 범죄피해자 지원기관인 (사)한국피해자지원협회(KOVA; Korea Organization Victicm Assistance)에서 2017년 7월 피해상담 전문가의 심리상담을 진행한 두 폭력 가정의 피해자녀들을 대상으로 이루어졌다. 연구참여자는 가정폭력에 대한 피해 호소가 10년이 넘은 가정으로서 폭력피해사실에 대해 경찰서에 직접 신고되어 접수된 이력이 있고 또 피해자녀와 피해자인 어머니가 단기쉼터에 입소하여 함께 거주한 경험이 있는 가정이었다. 가정폭력의 경우 자녀들은 특히, 미성년자인 경우 부모가 제공하는 생활공간에서 폭력피해를 입더라도 자발적으로 벗어나기 어려운 상태에 있으며, 폭력경험을 지속적이고 반복적으로 당하게 된다. 이에 가정폭력 피해자녀들이 현재 가해자-피해자 관계의 부모와 함께 거주하면서 어떤 감정 양상을 나타내고 있는지 그 특성을 정량화된 뇌파 데이터를 수집하고 분석하여 확인하고자 하였다. 뇌파측정은 서울불교대학원 부설 뇌과학연구소에서 진행하였으며, 뇌파측정 데이터 수집은 국제적으로 표준화된 19채널 뇌파측정도구인 브레인마스터를 사용하였고, 데이터 처리는 뉴로가이드를 사용하였다. 가정폭력을 경험한 피해자녀의 감정양상을 정량적 수치 및 뇌지형도를 통하여 분석한 결과 전두엽에 있어서 과잉서파의 문제, 알파파 좌우비대칭, 고베타파 좌우비대칭의 문제를 발견하였다.

• 한국환경과학회지
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• 제15권4호
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• pp.305-310
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• 2006

The color and structure of urban constructions is a factor of urban landscape and shows their characteristics. Hence the modern buildings deal with their materials and external appearance as an important factor, making up the urban image. But it was nearby impossible to evaluate the value of visual landscape with objective measuring method. Most of all, it depends on the subjective estimation of a few talented or high educated experts with a sense of beauty. Such kinds of estimation can in some cases include arbitrary interpretations. In relation to this kind of problems, it is tried here in this study to analyse the human response of brain wave pattern (EEG) with use of SD method, while the tested persons watch the urban landscape scenery constructed in a visual reality. The tested persons were 20 adult male and female with no color blindness and intact cognitive function. Light source with color filter was used for color environment in a dark soundproof chamber. The signal of EEG is analysed digitally and grouped into the ${\alpha}$ and ${\beta}$ waves. The result showed that relative power of ${\alpha}$ wave ratio increased in the natural landscape scenery with blue and green color. From these results it was possible to evaluate the human response, which is affected by urban and natural color and structure stimulation and it might be useful as an indicator of visual cognition amenity toward the design of urban construction environment.

• Journal of Ginseng Research
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• 제34권4호
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• pp.304-313
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• 2010

This study was undertaken to discover the effects and possible mechanisms of the effect of red ginseng extract (RGE) on spontaneous sleep. The effects of a low dose (10 mg/kg) and a high dose (200 mg/kg) of RGE were compared in rats. After recovery from a surgical operation enabling electroencephalograms recordings, rats were administered RGE orally. RGE was administered orally for 1 day or once per day for 5 days in either 10 or 200 mg/kg doses. Polygraphic signs were recorded for 12 h after oral administration of RGE. Both treatment with a large dose (200 mg/kg) of RGE for one day and treatment with either a large or a small dose for 5 days reduced the number of sleep.wake cycles. Daily treatment with RGE (either 10 or 200 mg/kg) for 5 days augmented NREM and total sleep, but reduced wakefulness. Delta wave activity recorded during non-REM (NREM) sleep and REM sleep was increased after one treatment with RGE (either 10 or 200 mg/kg). Delta wave activity during NREM was enhanced after daily treatment with RGE (either 10 or 200 mg/kg) for 5 days. Both alpha and beta subunits of the $\gamma$-aminobutyric acid $(GABA)_A$ receptor were significantly over-expressed in the hypothalamus of the RGE-treated groups. Moreover, the expression of glutamic acid decarboxylase was also increased in the hypothalamus. These results demonstrate that RGE may regulate spontaneous sleep via $GABA_A$ergic systems.

• 한국한의학연구원논문집
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• 제16권1호
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• pp.157-171
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• 2010

This study aimed to investigate the effect of four common types of Qigong position (standing, sitting, supine, and horse-riding position) on the autonomic nervous system. Thirty healthy subjects participated in this study once a week for four weeks. Electroencephalogram (EEG) was measured three times (before, during, and after the position) while the subject maintained one of four positions for ten minutes. There were significant changes in HRV components compared with EEG power spectra in the standing position. Especially, the ratio of low-to-high frequency (LF/HF) which represents a state of balance of autonomic nervous system was increased. In the sitting position, $\beta$ wave which reflects a state of alert consciousness was increased and both the sympathetic and parasympathetic nerves were activated. On the other hand, in the spine position, $\theta$ wave which signifies a state of relaxation was increased and heart rate (HR) was decreased. Activation of sympathetic and parasympathetic nerves was also observed in this position. Significant increases of indices related to awakening and concentration were observed accompanied by increase of HR and a sympathetic nerve was activated in the riding-horse position. In the present study, it was shown that each Qigong position caused various and significant changes in autonomic nervous system. It would be expected that these results can be applied in the choice of appropriate Qigong position according to objective of Qigong therapy although it is remained to further evaluate the effects of long-term maintenance of Qigong positions and repeated Qigong training.

• 대한한방소아과학회지
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• 제21권2호
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• pp.1-12
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• 2007

Objectives : Allergic children have known to have multiple behavior problems. Among them, attentional ability disorder is one of the most common problems. This study is to examine relationship between learning ability and allergic rhinitis by analyzing EEG status of children. Methods : We analyzed cognitive functions of two different children groups; 21 children with allergic rhinitis and 19 normal children with CANS 3000(Central & Autonomic Nervous System, LAXTHA Inc., Korea), cognitive functions assessment program by EEG. Results : 1. According to mean active EEG rhythm of Theta, Alpha, SMR, M-beta, there were no significant difference between allergic rhinitis and the normal group. 2. According to mean active EEG rhythm of right H-beta, Gamma wave allergic rhinitis group's value was significantly higher than that of the normal group. 3. According to mean cognitive strength, response, concentration, left / right brain activity and learning ability score, there were no significant difference between allergic rhinitis and the normal group. 4. According to mean workload score, allergic rhinitis group's value was significantly higher than that of the normal group. Conclusions : It is likely that allergic rhinitis group, which showed relatively high frequency EEG rhythm, is more fragile to stress and less active on mental processing. Along side with physical examination, psychological assessment should also be conjugated on treating children with allergic rhinitis.