• 약학회지
• /
• 제54권3호
• /
• pp.164-167
• /
• 2010

Column chromatographic separation of the MeOH extract from the aerial parts of Hibiscus manihot led to the isolation of four compounds. Their structures were characterized to be hentriacontane (1), palmitic acid (2), daucosterol (3) and 3-dihydrocaffeonyl-5-p-coumaroylquinic acid (4) by spectroscopic methods. The compounds (1~4) were for the first time reported from this plant. The solvent fractions were tested for their antioxidant activities by free radical scavenging and superoxide dismutase (SOD).

• 약학회지
• /
• 제52권4호
• /
• pp.259-263
• /
• 2008

Anti-inflammatory activity of the extracts of Hibiscus manihot was investigated through the evaluation of its inhibitory effect on the production of inflammatory biomarkers (i-NOS, COX-2) in RAW264.7 murine macrophage cells. Among the sequential solvent fractions (hexane, dichloromethane, ethyl acetate, n-butanol and water), the fractions of dichloromethane (1 ${\mu}g/ml$) and ethyl acetate (5 ${\mu}g/ml$) showed potential inhibitory activities on i-NOS and COX-2 activity in RAW264.7 cells. These results suggest that Hibiscus manihot might have an anti-inflammatory activity through the suppression of inflammatory markers.

• 한국자원식물학회지
• /
• 제34권6호
• /
• pp.536-541
• /
• 2021

In this study, we investigated whether Hibiscus manihot flowers (HMF) exhibits immunostimulatory activity in RAW264.7 cells. HMF increased the production of immunostimulatory factors such as NO, iNOS, IL-1β and TNF-α in RAW264.7 cells. TLR2 and TLR4 blocked HMF-mediated production of immunostimulatory factors in RAW264.7 cells. In addition, the inhibition of MAPK signaling pathway reduced HMF-mediated production of immunostimulatory factors. From these results, HMF is thought to promote the production of immunostimulatory factors through activating TLR2/4/MAPK signaling in macrophages. It is believed that HMF can be developed as an agent related to immune enhancement in the future.

• 한국작물학회:학술대회논문집
• /
• 한국작물학회 1994년도 춘계 학술대회지
• /
• pp.130-131
• /
• 1994

• 한국작물학회지
• /
• 제39권3호
• /
• pp.256-261
• /
• 1994

닥풀의 재래종(칠리종)을 계통분리하여 얻은 34계통중 초형이 다른 대표적인 단경, 중경 및 장경의 3개계통에 대하여 적심방법에 따른 식물체 각 부위의 생육 및 수량의 변이를 조사한 결과를 요약하면 다음과 같다. 1. 적심처리(개화직전)때의 초형별 생육특성은 경장은 단경계통 24cm, 중경 37cm, 장경계통이 80cm로서 그 차이가 컸으며 개화기는 단경계통의 8월3일에 비하여 경장이 길수록 2∼3일 늦었고 꽃봉우리수도 단경계통의 5개에 비하여 중경 19, 장경 24개로 경장이 길수록 많았으며 분지수는 4∼5개, 주경절수는 10개 내외로 큰 차이가 없었다. 2. 닥풀의 주 이용부위인 생근수량은 초형별로는 장경일수록 많으며 기타 경중 및 삭중과 각 부위의 건물수량도 동일한 경향이었다. 3. 적심방법에 따른 생근수량은 어느 초형에서나 주경과 분지를 함께 적심한 구에서 가장 증수되었으며 화뢰적제구에서도 많은 증수를 보았으나 주경적심의 효과는 거의 없었다. 전체평균에서는 무처리구의 459kg/10a(100)에 비하여 주경 및 분지를 함께 적심한 경우 102%, 화뢰적제에서도 66%의 증수를 보였다. 4. 생체의 구성비율은 같은 초형에서는 적심방법 간에서는 큰 차이가 없었으나 초형간에 있어서는 지상생육량이 적은 단경계통의 생근중비율(전중대)이 약 40%로 가장 높고 생육량이 많은 중경, 장경계통일수록 낮은 경향이었다. 5. 뿌리의 건조비율(건근중/생근중)은 단경계통 이 31.6%인데 비하여 중경 38.1%, 장경계통은 40.2%로서 생근수량이 많았던 장경계통일수록 높은 경향이었다.

• 한국한의학연구원논문집
• /
• 제7권1호
• /
• pp.55-66
• /
• 2001

According to the customary, naming is done after the subject is in existence. But the name's Hae-ba-ra-gi(해바라기), 향일규(向日葵), 향일화(向日花))' has been used as an alias of Hibiscus manihot L.(닥풀) long before Helianthus annuus L.(sunflower) was brought in to Korea. And now the usage of the name has been conversed since them. Since the incorrect record of '葵藿' and '葵花'as '해바라기' in ${\ulcorner}$조선어사전(朝鮮語辭典)${\lrcorner}$(1920), the mistake has been carried on this must be corrected from now on. Incorrect record of hollyhock(蜀葵花) '해바라기' in ${\ulcorner}$몽유(蒙喩))${\lrcorner}$(1810) took a role in this incorrect trend.

• 한국자원식물학회:학술대회논문집
• /
• 한국자원식물학회 2007년도 추계학술발표회
• /
• pp.357.1-357.1
• /
• 2007

• 한국자원식물학회지
• /
• 제36권6호
• /
• pp.541-548
• /
• 2023

In the present study, the effects of HML on lipolysis, adipocyte browning, autophagy, and proliferation were investigated. HML affected lipolysis by increasing the protein levels of ATGL and HSL, and phosphorylation levels of HSL and AMPK. Furthermore, HSL decreased the perilipin-1 levels. In addition, free glycerol content was increased by HML treatment. HML affected adipocyte browning by increasing the protein levels of UCP-1, PGC-1α, and PRDM16. In addition, HML affected autophagy by increasing the levels of LC3-I and LC3-II, and decreasing those of SQSTM1/p62. Moreover, HML affected adipocyte proliferation by suppressing the proliferation of 3T3-L1 cells due to arrest of the cell cycle via blocking the expression of β-catenin and cyclin D1. These results suggest that HML induces lipolysis, adipocyte browning, autophagy, and inhibits excessive proliferation of adipocytes.

• 한국의사학회지
• /
• 제14권1호
• /
• pp.31-47
• /
• 2001

According to the customary, naming is done after the subject is in existence. But the name "Haebaragi"(Hyangilgyu, Hyangilhwa) has been used as an alias of Hibiscus manihot L, long before Helianthus annuus L was brought in to Korea, and now the usage of the name has been conversed since then. Since the incorrect record of Gyugwak and Gyuhwa as Haebaragi in "Chosunesajun"(Dictionary of Chosun language) published under Chosunchongdokbu in 1920, the mistake has been carried on and this must be corrected from now on. Incorrect record of hollyhock(Chokgyuwha) as Haebaragi in "Mong-u" (1810) took a role in this incorrect trend.