• YAKHAK HOEJI
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• v.54 no.3
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• pp.164-167
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• 2010

Column chromatographic separation of the MeOH extract from the aerial parts of Hibiscus manihot led to the isolation of four compounds. Their structures were characterized to be hentriacontane (1), palmitic acid (2), daucosterol (3) and 3-dihydrocaffeonyl-5-p-coumaroylquinic acid (4) by spectroscopic methods. The compounds (1~4) were for the first time reported from this plant. The solvent fractions were tested for their antioxidant activities by free radical scavenging and superoxide dismutase (SOD).

• YAKHAK HOEJI
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• v.52 no.4
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• pp.259-263
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• 2008

Anti-inflammatory activity of the extracts of Hibiscus manihot was investigated through the evaluation of its inhibitory effect on the production of inflammatory biomarkers (i-NOS, COX-2) in RAW264.7 murine macrophage cells. Among the sequential solvent fractions (hexane, dichloromethane, ethyl acetate, n-butanol and water), the fractions of dichloromethane (1 ${\mu}g/ml$) and ethyl acetate (5 ${\mu}g/ml$) showed potential inhibitory activities on i-NOS and COX-2 activity in RAW264.7 cells. These results suggest that Hibiscus manihot might have an anti-inflammatory activity through the suppression of inflammatory markers.

• Korean Journal of Plant Resources
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• v.34 no.6
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• pp.536-541
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• 2021

In this study, we investigated whether Hibiscus manihot flowers (HMF) exhibits immunostimulatory activity in RAW264.7 cells. HMF increased the production of immunostimulatory factors such as NO, iNOS, IL-1β and TNF-α in RAW264.7 cells. TLR2 and TLR4 blocked HMF-mediated production of immunostimulatory factors in RAW264.7 cells. In addition, the inhibition of MAPK signaling pathway reduced HMF-mediated production of immunostimulatory factors. From these results, HMF is thought to promote the production of immunostimulatory factors through activating TLR2/4/MAPK signaling in macrophages. It is believed that HMF can be developed as an agent related to immune enhancement in the future.

• Proceedings of the Korean Society of Crop Science Conference
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• 1994.06a
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• pp.130-131
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• 1994

• KOREAN JOURNAL OF CROP SCIENCE
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• v.39 no.3
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• pp.256-261
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• 1994

To investigate the effects of topping method on the yield and major agronomic traits of three varieties differed in plant type of Hibiscus manihot the experiments were carried out Mokpo Branch Station of Crop Experiment Station, in 1993. Fresh weight of root, dry weight of culm, dry weight of capsule and dry matter ratio on root were highest in the long culmed variety, and at the plots with topping of growing point in main culm and branches(Treatment No.3). Considering from the above results, optimum topping method seemed to be topping of growing point in main culm and branches in the long culmed variety.

• Korean Journal of Oriental Medicine
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• v.7 no.1
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• pp.55-66
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• 2001

According to the customary, naming is done after the subject is in existence. But the name's Hae-ba-ra-gi(해바라기), 향일규(向日葵), 향일화(向日花))' has been used as an alias of Hibiscus manihot L.(닥풀) long before Helianthus annuus L.(sunflower) was brought in to Korea. And now the usage of the name has been conversed since them. Since the incorrect record of '葵藿' and '葵花'as '해바라기' in ${\ulcorner}$조선어사전(朝鮮語辭典)${\lrcorner}$(1920), the mistake has been carried on this must be corrected from now on. Incorrect record of hollyhock(蜀葵花) '해바라기' in ${\ulcorner}$몽유(蒙喩))${\lrcorner}$(1810) took a role in this incorrect trend.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2007.11a
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• pp.357.1-357.1
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• 2007

• Korean Journal of Plant Resources
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• v.36 no.6
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• pp.541-548
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• 2023

In the present study, the effects of HML on lipolysis, adipocyte browning, autophagy, and proliferation were investigated. HML affected lipolysis by increasing the protein levels of ATGL and HSL, and phosphorylation levels of HSL and AMPK. Furthermore, HSL decreased the perilipin-1 levels. In addition, free glycerol content was increased by HML treatment. HML affected adipocyte browning by increasing the protein levels of UCP-1, PGC-1α, and PRDM16. In addition, HML affected autophagy by increasing the levels of LC3-I and LC3-II, and decreasing those of SQSTM1/p62. Moreover, HML affected adipocyte proliferation by suppressing the proliferation of 3T3-L1 cells due to arrest of the cell cycle via blocking the expression of β-catenin and cyclin D1. These results suggest that HML induces lipolysis, adipocyte browning, autophagy, and inhibits excessive proliferation of adipocytes.

• The Journal of Korean Medical History
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• v.14 no.1
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• pp.31-47
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• 2001

According to the customary, naming is done after the subject is in existence. But the name "Haebaragi"(Hyangilgyu, Hyangilhwa) has been used as an alias of Hibiscus manihot L, long before Helianthus annuus L was brought in to Korea, and now the usage of the name has been conversed since then. Since the incorrect record of Gyugwak and Gyuhwa as Haebaragi in "Chosunesajun"(Dictionary of Chosun language) published under Chosunchongdokbu in 1920, the mistake has been carried on and this must be corrected from now on. Incorrect record of hollyhock(Chokgyuwha) as Haebaragi in "Mong-u" (1810) took a role in this incorrect trend.