• Nuclear Engineering and Technology
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• v.41 no.9
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• pp.1205-1214
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• 2009

The critical heat flux (CHF) levels that occurred due to exponential heat inputs for varying periods to a 1.0-mm diameter horizontal cylinder immersed in various liquids were measured to develop an extended database on the effect of high subcoolings for quasi-steady-state and transient maximum heat fluxes. Two main mechanisms of CHF were found. One mechanism is due to the time lag of the hydrodynamic instability (HI) which starts at steady-state CHF upon fully developed nucleate boiling, and the other mechanism is due to the explosive process of heterogeneous spontaneous nucleation (HSN) which occurs at a certain HSN superheat in originally flooded cavities on the cylinder surface. Steady-state CHFs were divided into three regions for lower, intermediate and higher subcooling at pressures resulting from HI, transition and HSN, respectively. HSN consistently occurred in the transient boiling CHF conditions that correspond to a short period. It was also found that the transient boiling CHFs gradually increased, then rapidly decreased and finally increased again as the period became shorter.

• Journal of Yeungnam Medical Science
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• v.36 no.3
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• pp.163-182
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• 2019

The primary function of intraoperative frozen consultation is to provide an as accurate and prompt diagnosis as possible during surgery and to guide the surgeon in further management. However, the evaluation of frozen section (FS) is sometimes difficult because of suboptimal tissue quality and frozen artifacts compared with routinely processed tissue section. The pathologist responsible for the FS diagnosis requires experience and good judgment. Ovarian tumors are a heterogeneous group of tumors including primary surface epithelial tumors, germ cell tumors and sex cord-stromal tumors, secondary tumors, and other groups of tumors of uncertain histogenesis or nonspecific stroma. Intraoperative FS is a very important and reliable tool that guides the surgical management of ovarian tumors. In this review, the diagnostic key points for the pathologist and the implication of the FS diagnosis on the operator's decisions are discussed.

• Molecules and Cells
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• v.45 no.6
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• pp.353-361
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• 2022

Chronic rhinosinusitis (CRS) is a multifactorial, heterogeneous disease characterized by persistent inflammation of the sinonasal mucosa and tissue remodeling, which can include basal/progenitor cell hyperplasia, goblet cell hyperplasia, squamous cell metaplasia, loss or dysfunction of ciliated cells, and increased matrix deposition. Repeated injuries can stimulate airway epithelial cells to produce inflammatory mediators that activate epithelial cells, immune cells, or the epithelial-mesenchymal trophic unit. This persistent inflammation can consequently induce aberrant tissue remodeling. However, the molecular mechanisms driving disease within the different molecular CRS subtypes remain inadequately characterized. Numerous secreted and cell surface proteins relevant to airway inflammation and remodeling are initially synthesized as inactive precursor proteins, including growth/differentiation factors and their associated receptors, enzymes, adhesion molecules, neuropeptides, and peptide hormones. Therefore, these precursor proteins require post-translational cleavage by proprotein convertases (PCs) to become fully functional. In this review, we summarize the roles of PCs in CRS-associated tissue remodeling and discuss the therapeutic potential of targeting PCs for CRS treatment.

• Nuclear Engineering and Technology
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• v.56 no.3
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• pp.772-784
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• 2024

The hexagonal nodal code RENUS has been enhanced to handle irregularly deformed hexagonal assemblies. The underlying RENUS methods involving triangle-based polynomial expansion nodal (T-PEN) and corner point balance (CPB) were extended in a way to use line and surface integrals of polynomials in a deformed hexagonal geometry. The nodal calculation is accelerated by the coarse mesh finite difference (CMFD) formulation extended to unstructured geometry. The accuracy of the unstructured nodal solution was evaluated for a group of 2D SFR core problems in which the assembly corner points are arbitrarily displaced. The RENUS results for the change in nuclear characteristics resulting from fuel deformation were compared with those of the reference McCARD Monte Carlo code. It turned out that the two solutions agree within 18 pcm in reactivity change and 0.46% in assembly power distribution change. These results demonstrate that the proposed unstructured nodal method can accurately model heterogeneous thermal expansion in hexagonal fueled cores.

• Korean Chemical Engineering Research
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• v.59 no.1
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• pp.21-34
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• 2021

Chitosan nanoparticles (CNPs) and Lactococcus lactis (L. lac.) were used as adsorbents to evaluate the adsorption performance of endocrine hormones, which are phthalates, in the healthy food packages. CNPs were produced through the cross bond with tripolyphosphate (TPP), and L. lac.-CNPs were prepared through the introduction of L. lac. during the preparation. The various functional groups of all adsorbents were identified using Fourier transform infrared spectroscopy (FTIR). Adsorption isotherm and adsorption kinetic confirmed the adsorption behavior and mechanism of CNPs, L. lac. and L. lac.-CNPs. The adsorption behavior of DBP and DEP for all particles was more suitable for the Freundlich adsorption isotherm model than for the Langmuir adsorption isotherm model, which means that the surface of the particles is heterogeneous. The adsorption mechanism was more suitable for the Pseudo-2nd-order model than for the Pseudo-1st-order model. This means that due to the presence of various functional groups on the particle surface, the adsorption of DBP and DEP is dominated by chemical adsorption such as electrostatic attraction and hydrogen bonding rather than physical adsorption. Finally, it was confirmed that the preparation of CNPs and L. lac.-CNPs can be performed easily and quickly, and it could be used as a cheaper adsorbent that can effectively remove phthalates.

• Analytical Science and Technology
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• v.21 no.3
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• pp.237-243
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• 2008

Nano core shell structures of $TiO_2$ particles coated on surface of ZnO nanoparticles were prepared by the polymerized complex and sol-gel method. The average particle size of ZnO by the polymerized complex method showed 100 nm and the average particle size of $TiO_2$ by the sol-gel method showed below 10 nm. The average particle size of $ZnO@TiO_2$ nano core shell struture represented about 150 nm. The agglomeration between the ZnO particles using the polymerized complex method was highly controlled by the uniform absorption of $TiO_2$ colloid on the spherical ZnO surfaces. The driving force of heterogeneous bonding between ZnO and $TiO_2$ was induced by the Coulomb force. The ZnO and $TiO_2$ particles electrified with + and - charges, respectively, resulted in strong bonding by the difference of iso-electric point (IEP) when they laid neutrality pH area, depending on the heterogeneous surface electron electrified by the different zeta potential on the pH values.

• 한국신재생에너지학회:학술대회논문집
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• 2006.11a
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• pp.40-43
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• 2006

Public demand for the heat pump system as a next generation energy equipment is increasing for its eco-friendly and cost-effective advantage. Many researches have been concentrated on how to calculate and develop its own efficiency, while the possible effect of the heat pump operation on the whole subsurface temperature distribution is relatively less considered, During the current study, subsurface temperature disturbance caused by seasonal surface temperature cycle in Busan area and general W-tube heat pump operation is simulated in 3-dimensional heterogeneous medium. It shows that subsurface deeper than 10m from the surface remains nearly unchanged throughout the 4 seasons and groundwater convect ion in highly permeable layer near the surface acts like a main path of heat plume from heat pump system, This implies the significance of detail descript ion in shallow sedimentary layer or highly permeable layer which plays an important role on the regional flow advection and heat transfer. Also, the effect of groundwater convection increases when the arrangement of the 2 injection pipes and 2 extract ion well is maintained parallel to groundwater flow. Therefore, more careful and detail investigation is required before installation and operation of heat pump system that it may not cause any possible change of microbial ecosystem in the shallow subsurface environment or 'contamination of temperature' for groundwater use as well as the loss of efficiency of the equipment itself. This can also help to design the optimized grouting system for heat pump.

• Korean Journal of Ichthyology
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• v.13 no.1
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• pp.19-23
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• 2001

The full-grown oocyte envelope of the two spined loaches, Niwaella multifasciata and Kichulchoia brevifasciata, was examined by electron microscopy. The oocyte is surrounded by its envelope, and an external modification (an adhesive structure) in the surface of the envelope is present. The envelope consists of two layers, a zona radiata externa which is the site of the adhesive structure, and a zona radiata interna, which has heterogeneous, electron-dense multi layers. The surface (zona radiata externa) of the envelope in N. multifasciata is equipped with short villuslike protuberances, which have a length of 1.5~2.5 ${\mu}m$ and are separated from each other by a distance of 2~2.5 ${\mu}m$. In contrast, K. brevifasciata has undulating or wave-like structures that extend over the entire oocyte surface. The waves are 1.5~2.5 ${\mu}m$ in length and are separated a distance of 2.5~3.3 ${\mu}m$ from each other.

• Polymer(Korea)
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• v.39 no.2
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• pp.300-310
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• 2015

In this study, we modified silica nanoparticles with N-[3-(trimethoxysilyl)propyl]ethylenediamine (TPED) silane coupling agent, which has one primary and one secondary amino groups in a molecule, to introduce amino groups on the silica surface. After modification of silica, we used 3-(acryloyloxy)-2-hydroxypropyl methacrylate (AHM) to introduce methacrylate groups by Michael addition reaction. We found about 30% of N-H groups on the TPED modified silica surface reacted with acrylate groups of AHM compared to about 85% of reaction between N-H groups of pure TPED with acrylate groups of pure AHM. This lower degree of Michael addition reaction for heterogeneous reaction between N-H groups on the solid TPED modified silica and liquid AHM compared to homogeneous reaction between pure liquid TPED and pure liquid AHM may be caused by lower mobility of grafted amino groups of TPED moiety and higher steric hindrance caused by solid silica particles.

• Korean Chemical Engineering Research
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• v.46 no.4
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• pp.647-659
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• 2008

Colloids are a heterogeneous system in which particles of a few nanometers to hundreds micrometers in size are finely dispersed in liquid medium, but show homogeneous properties in macroscopic scale. They have attracted much attention not only as model systems of natural atomic and molecular self-assembled structures but also as novel structural materials of practical applications in a wide range of areas. In particular, recent advances in colloidal science have focused on nano-bio materials and devices which are essential for drug discovery and delivery, diagnostics and biomedical applications. In this review, first we introduce nano-bio colloidal systems and surface modification of colloidal particles which creates various functional groups. Then, various methods of fabrication of colloidal particles using holographic lithography, microfluidics and virus templates are discussed in detail. Finally, various applications of colloids in metal inks, three-dimensional photonic crystals and two-dimensional nanopatterns are also reviewed as representative potential applications.