• 한국식품저장유통학회지
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• 제24권2호
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• pp.187-195
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• 2017

전통장류로부터 분리 된 효소 활성 및 probiotic효과가 우수한 유산균을 접종하여 제조된 콩 발효물의 품질특성을 분석하였다. 일반세균수는 유산균을 접종한 콩 발효물이 $4.10{\times}10^9-7.75{\times}10^9CFU/mL$으로 나타났다. 유산균수를 측정 결과 유산균을 접종한 콩 발효물은 $2.85{\times}10^9-4.35{\times}10^9CFU/mL$으로 높게 나타났다. ${\alpha}-Amylase$ 활성 측정 결과 I13과 JSA22를 접종한 콩 발효물은 $1.05{\pm}0.91$, $3.13{\pm}1.39unit/mL$으로 가장 낮았다. 또한 JSB22는 $12.56{\pm}1.39unit/mL$으로 유산균 접종 콩 발효물 중 가장 높았다. Protease 활성 측정 결과, control이 $333.13{\pm}17.68unit/mL$으로 가장 높았으며, 유산균을 접종한 콩 발효물은 JSB22를 접종한 콩 발효물이 $166.67{\pm}2.37unit/mL$으로 높았다. 환원당 함량을 측정한 결과 유산균 접종 콩 발효물 중 JSB22가 $1.23{\pm}0.035%$로 가장 높았다. 아미노태 질소 함량 또한 JSB22가 $94.52{\pm}3.86mg%$으로 높게 나타났다. 아미노산함량을 측정한 결과 glutamic acid, aspartic acid, arginine, leusine 순으로 많이 함유하고 있었다. 유기산 함량을 분석한 결과 lactic acid, oxalic acid가 많이 측정되었다. 향기분석 측정 결과 총 39종(ester류 2종, ketose 5종, alcohol 7종, hydrocarbons 14종, heterocyclic compounds 3종, acid 4종, other 5종)이 검출되었다. 세 가지 균주에서 공통적으로 benzene(81.43-98.54 ppm)과 acetic acid, ethyl ester(44.79-56.74 ppm)가 많이 검출되었다. 본 연구는 전통장류 유래 기능성 우수 유산균주를 이용한 콩발효물의 기초적 품질특성에 관한 내용으로 미생물학적 및 이화학적 관련 특성을 분석하여 제시하였다. 유산균 이용 생물전환에 의한 다양한 기능성 물질이 생성 되었을 것으로 생각된다. 본 연구결과가 기능성 콩 발효소재 개발의 좋은 기초자료가 될 것으로 생각되며, 장류 품질개선 기능성 스타터 개발에 활용 될 수 있을 것으로 기대된다.

• 대한화학회지
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• 제55권4호
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• pp.594-602
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• 2011

4[N-(furfural)amino]antipyrine semicarbazone(FFAAPS)와 질산 란탄(III)이 형성하는 배위화합물의 입체화학에 미치는 ${\alpha}$-, ${\beta}$- 및 ${\gamma}$-picolines의 영향을 연구하였다. 이들 배위화합물의 일반적 조성은 [Ln(FFAAPS)$(NO_3)_3$Pic] (Ln=La, Pr, Nd, Sm, Gd, Tb, Dy 또는 Ho 및 Pic=${\alpha}$-, ${\beta}$- or ${\gamma}$-picolines)이다. 모든 배위화합물은 원소분석, 분자량, 몰전기전도도, 자기수자율, 적외선 및 자외선 스펙트럼으로 특성을 조사하였다. 적외선 연구결과 FFAAPS는 N, N, O 주개를 갖는 중성 삼배위 리간드로 행동하는 반면, ${\alpha}$-, ${\beta}$- 또는 ${\gamma}$-picoline는 헤테로 N-원자를 통하여 란탄(III) 이온에 배위된다. 질산 음이온은 이들 화합물에서 이배위로 결합한다. 자외선 스펙트럼 결과로부터 전자구름 퍼짐 효과(${\beta}$), covalence factor($b^{1/2}$), Sinha parameter (${\delta}%$) 및 covalence angular overlap parameter(${\eta}$)를 계산하였다. 이들 착물의 열적성질을 열무게 분석법에 의해 연구하였다. 본 화합물에 있어서 란탄(III)의 배위수는 10으로 조사되었다. 기본 리간드인 FFAAPS와 착물의 항박테리아 선별조사 결과, 이들 착물은 중간 정도의 항박테리아 활성을 보였다.

• 한국식품영양학회지
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• 제25권4호
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• pp.1092-1098
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• 2012

바닥소재에 따른 천일염의 향기성분은 네 가지 종류의 천일염에서는 4-methyl-2-pentanone, 5-methyl-3-hexanone, 4-methyl-3-penten-2-one, 2-hexanol, benzothiazole, 2,4-bis-(1,1-dimethylethyl)-phenol, 1,3,5-tri-tert-butyl benzene 등 케톤류, 알콜류 그리고 방향족 화합물류와 같은 공통된 향기성분이 검출되었다. 친환경소금으로 알려진 토판염, 일반적으로 알려져 있는 천일염인 PVC 장판염과 그리고 친환경소재의 PP 장판염의 차이를 구별할 수 있는 향기성분은 검출되지 않았으며, 신안군에서 생산된 천일염에서만 methyl isobutyl ketone 성분이 검출되어 생산지역에 따라 차이가 있었다. 편백나무에 보관했던 천일염의 향기성분은 오동나무와 소나무에 보관했던 천일염의 향기성분보다 다양한 종류가 검출되었으며, 이는 저장용기의 나무소재에 따라 천일염에 이행된 향기성분이 다르기 때문으로 생각된다. 이와 같이 독특한 향기성분을 천일염에 부여하는 것은 천일염 산업에 새로운 고부가가치를 창출할 수 있는 방법이라 판단되며, 소금 유통시장에서 적용가능성이 높은 연구가 수반되어야 할 것이다.

• Journal of Photoscience
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• 제7권4호
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• pp.143-148
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• 2000

Studies have been conducted to explore single electron transfer(SET) promoted photocyclization of ($\omega$-phthalimidoalkoxy)acetic acids(alkoxy=ethoxy, n-propoxy and n-butyloxy). Photocyclizations occur in methanol or acetone in high yields to produce cyclized products in which phthalimide carbonyl carbon is bonded to the carbon of side chain in place of the carboxylic group. These photocyclizations are thought to proceed through pathways involving intramolecular SET from oxygen in the $\alpha$-carboxymethoxy groups to the singlet excited state phthalimide moieties followed by decarboxylation of the intermediate $\alpha$-carboxymethoxy cation fadicals and cyclizations by radical coupling. The photocyclizations occur ca. three times faster in both methanol or acetone with one equivalent of sodium hydroxide added to the reactions and occur slower in acetone than in methanol. The efficient and regiselective cyclization reactions observed for photolyses in methanol represent synthetically useful processes for construction of heterocyclic compounds.

• 한국식품저장유통학회지
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• 제6권1호
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• pp.121-135
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• 1999

Effective synthetic antioxidants such as butylated hydroxyanisole(BHA) and butylated hydroxytoluene(BHT) have been widely used in the food industry, but they are suspected to be toxic and carcinogenic effects. Therefore, the development of safely available natural antioxidants such as ascorbic acid, ${\alpha}$-tocopherol, ${\beta}$-carotene, flavonoids and selenium is essential. In particular, flavonoids, 2-phenyl-benzo-${\alpha}$-pyrones, are polyphenolic compounds that occur ubiquitously in food of plant origin. flavonoids occur in foods generally as O-glycosides with sugars bound usually at the C\ulcorner position. And variations in their heterocyclic ring gibes rise to flavones, flavonols, flavanones, flavanols, catechins, anthocyanidins, chalcone and isoflavones. Vegetables, fruits, and beverages are the main dietary sources of the flavonols, primarily as quercetin, kaempferol, and myricetin and the corresponding flavones, apigenin and luteolin. These flavonoids have biological activity such as antioxidant, anti-inflammatory, antithrombotic, antimutagenic, anticarcimogenic antiallergic and antimicrobial activity effects in vitro and in vivo. Flavonoids posses strong antioxidant activities acting as oxygen radicals scavenger, metal chelators and enzyme inhibitor. The antioxidant activity of flavonoids is determined by their molecular structure and more specially, by the position and degree of hydroxylation of the ring structure. All flavonoids with the 3`, 4`-dihydroxy(ortho-dihydroxy) posses marked antioxidant activity. And antioxidant activity increases with the number of hydroxyl groups substituted on the A-and B-rings. There is as yet no certainty about the effect of the presence of a double bond between C\ulcorner and C\ulcorner on the antioxidant activity of flavonoids.

• Environmental Engineering Research
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• 제22권3호
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• pp.312-319
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• 2017

The treatment of dyeing wastewater is not easy because dyes are mainly aromatic, heterocyclic compounds. The most effective technologies and methods to treat dyeing wastewater are costly and involve materials that are difficult to regenerate after use. Therefore, it is necessary to develop cost-effective, eco-friendly technologies to treat dyeing wastewater. The aim of this study was to investigate the removal of sulfur blue 11 (CI 53235) anionic dye using methyl esterified sericite (ME-sericite) adsorbents in an aqueous solution. The results are discussed in terms of the ME-sericite particle size, temperature, pH value and initial sorption rate according to the initial sulfur blue concentration. In addition, we analyzed the adsorption kinetics using a Pseudo-second-order model with the desorption and reusability. The methyl esterification caused a considerable increase in the specific surface area from 4.45 to $17.62m^2/g$. The ME-sericite adsorbents successfully removed > 98% of the sulfur dye in the aqueous solution. For the adsorption of 1 mg of sulfur dye, approximately 4.6 to 6.6 g/L ME-sericite were required. The desorption process was carried out by mixing a NaOH eluent to desorb 90.56% of the sulfur dye with 2 h of contact time. Thus, the ME-sericite is a promising adsorbent to treat dyeing wastewater due to its low dose requirement, high removal efficiency and inexpensive material.

• Archives of Pharmacal Research
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• 제15권1호
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• pp.87-90
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• 1992

The syntheses of novel heterocyclic base modified pyrimidine nucleosides are described. 5, 6-dimethyl-4-hydroxy-3-methoxy-1-$(\beta$-D-ribofuranosyl)2(1H)-pyridinone 7 was synthesized by condensation of silylated 5, 6-dimethyl4-hydroxy-3-methoxy-2(1H)-pyridione 7 was synthesized by condensation of silylated 5, 6-dimethyl-4-hydroxy-3-methoxy-2(1H)-pyridinone with $\beta$-D-ribofuranose-1-acetate-2, 3, 5-tribenzoate in dichloroethane in the presence of Lewis acid followed by debenzoylation. The 2, 2'-anhydro-5, 6-dimethyl-2-hydroxy-3-methoxy-1-$\beta$-D-arabinofuranosyl-4-pyridinone 8 was obtained from the reaction of the free ribonucleoside 7 and diphenyl carbonate in DMF. None of these compounds showed any significant antiviral ad antitumor activities in vitro tests.

• 대한화학회지
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• 제9권2호
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• pp.88-95
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• 1965

퓨란, 醋酸풀퍼릴, 풀퍼릴알코올과 마레인酸無水物을 에틸 에테르 存在下에서 附加反應시켜 exo附加物을 만들고 이 化合物들에 對한 臭素化反應을 물 存在下에서 行한 바 各各 모노부롬化락톤 및 디브롬酸을 生成하였으며 락톤의 生成收率은 轉位된 carbonium ion에 對한 carboxylic acid의 反應기여(participation)에 依하여 決定되면 化合物 自體의 立體條件(steric requirement)이 그 기여에 영향을 준다는 것을 究明하였다. 퓨란附加物을 有機溶媒(四鹽化炭素, 메틸렌크로라이드)存在下에서 臭素化反應하면 二臭化物이 生成하고 光線 存在下에서 鹽素化反應하면 四鹽化反應物이 生成됨을 究明하였다. 各 化合物의 合成方式 및 反應過程에 關하여 論及하였다.

• 대한화학회지
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• 제55권6호
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• pp.940-951
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• 2011

Reaction of 1-methylpyrimidine-(1H,3H,5H)-2,4,6-trione (1-MBA 1) as an unsymmetrical barbituric acid with cyanogen bromide and various aldehydes in the presence of triethylamine and/or pyridine afforded diastereomeric mixtures of new class of heterocyclic stable 5-aryl-1,1'-dimethyl- and 5-aryl-3,1'-dimethyl-1H,1'H-spiro[furo[2,3-d]pyrimidine-6,5'-pyrimidine]2,2',4,4',6'(3H,3'H,5H)-pentaones which are dimeric forms of 1-methyl barbiturate at the range of $0^{\circ}C$ to room temperature. In the reaction of some aldehydes with 1-MBA and BrCN were afforded a mixture of diastereomers. Another two aldehydes such as 4-cyano- and 2-hydroxybenzaldehydes gave exclusively two diastereomers in which binded to the salt of triethylammonium hydrobromide by intermolecular H-bond in ratio of 1:1. 4-Hydroxybenzaldehyde and 2-pyridinecarbaldehyde gave exclusively one diastereomer under the same condition. Aldehydes possessing strong electron-donor were produced exclusively two geometric isomers of Knoevenagel adduct (E- and Z-isomers). The structures of compounds were deduced by $^1H$ NMR, $^{13}C$ NMR and FT-IR spectroscopy. Mechanism of the formation is discussed.

• 한국염색가공학회지
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• 제17권6호
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• pp.1-10
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• 2005

Disperse dyes derived from heterocyclic compounds such as phenylindole, pyridone, diaminopyridine, and carbazole have been known to exhibit high light fastness and bathochromic shift compared to the coursponding aminoazobenzene. The synthetic method to obtain diaminopyridine derivatives, which can be used as coupling components, was chlorination of pyridone with phosphorous oxychloride, followed by substitution with various primary amines. Four azo disperse dyes were synthesized by coupling four diaminopyridines with 2-cyano-4-nitroaniline as a diazo component. Structures of these dyes were confirmed by $^1H$ NMR spectroscopy. The wavelengths of maximum absorption of the synthesized disperse dyes were in the range of $517\~528nm$, and molar extinction coefficients were $45,700\~50,100$. The dyeability of four disperse dyes toward PET fiber was generally good. Wash and rubbing fastnesses were excellent, while light and dry heat fastness were good.