• Title/Summary/Keyword: Hematological values

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Effects of Anesthesia by Electric Acupuncture on Blood Pattern in Dogs (개 전침마취에 있어서의 혈액학적변화에 관한 연구)

  • Seo Doo-Seok
    • Journal of the korean veterinary medical association
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    • v.15 no.8
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    • pp.453-457
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    • 1979
  • The hematological changes by electric acupuncture in dags has been studied, using 5 mongel dags, by determining the values af erythrocyte count, hemoglobin content, hematcrit ratio, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular he

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Effects of whole-body gamma-irradiation on the peripheral blood of ICR mouse (ICR 마우스에서 방사선 조사 용량에 따른 혈액변화의 관찰)

  • Kim, Sung-Ho;Lee, Jong-Hwan;Kim, Se-Ra;Lee, Hae-June;Lee, Yun-Sil;Kim, Tae-Hwan;Ryu, Si-Yun;Jo, Sung-Kee;An, Mi-Yeong
    • Korean Journal of Veterinary Research
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    • v.42 no.2
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    • pp.183-190
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    • 2002
  • The effects of ionizing radiation on the peripheral blood elements of ICR mouse were examined after varying doses of whole-body gamma-irradiation. ICR mice (n=50) were exposed to 0, 2, 4, 6 and 8 Gy gamma-ray ($^{60}Co$) at 10 Gy/min. The animals were studied for their hematological response on days, 3, 7, 14, 21, 42 and 56 post irradiation. No significant change was noted in erythrocyte, hemoglobin and hematocrit values after irradiation with dose of 2 Gy. Decreasing erythrocyte, hemglobin and hematocrit values occured after irradiation with doses of more than 4 Gy on day 7 after irradiation followed by a sharp fall on day 14. A recovery in these values was noted after 3 weeks of irradiation. Thrombocyte counts decreased on day 3, reaching minimal values on day 7. The total number of leukocytes was reduced on day 3, mainly because of a decrease in the lymphocyte population. An evident lymphopenia and neutropenia occur almost on the day 3 and last up to the day 28 after irradiation. All of the hematological values decreased in the blood in a dose-dependent manner at the same time.

The Effect of Supplementary Feeding of Tannic acid on Growth and Hematological Changes in Rats Fed High Fat Diet (탄닌산(tannic acid) 첨가가 고지방 식이 흰쥐의 성장과 혈액학치 및 혈액화학치의 변화에 미치는 영향)

  • Hwang Eui-kyung
    • Journal of Veterinary Clinics
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    • v.22 no.2
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    • pp.108-113
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    • 2005
  • This study was performed to investigate the growth rate, hematological and serological changes of the rats when they were fed with the high fat diets supplemented with or without the tannic acid for five weeks. Thirty-two Sprague-Dawley male rats(235.7\pm10.7g\;of\;body\;weight)$ were randomly divided into four groups, control group and three treatment groups(T1, T2 and T3). Rats in control group were fed with the high fat diet containing $15\%\;lard,\;1\%$ cholesterol and $0.5\%$ sodium cholate(wt/wt) which was modified from the formula of American Institute of Nutrition (AIN)-76 diet and rats in treatment groups were fed with above diet supplemented with $0.25\%(T1),\;0.5\%(T2)$ or $0.75\%(T3)$ of tannic acid(wt/wt), respectively. The supplementation of tannic acid(TA) did not affect the final body weight, gain of body weight and feed intake of rats in both control and treatment groups. The numbers of red blood cells, hemoglobin concentrations and hematocrit values in blood of rats showed no significant differences between control group and treatment groups. The glucose concentration and albumin/globulin(A/G) ratio of rats in treatment groups were slightly lower than that of control group without significance. The values of total protein, albumin and globulin showed no significant differences between control group and treatment groups. The values of total cholesterol, low density lipoprotein­cholesterol and atherogenic index in sera of rats in treatment groups were much lower than that of control group without significance. The values of triglycerides in sera of rats in T3 group were significantly lower than that of control group (p<0.05). The values of AST and ALT in sera of rats in T3 group were significantly lower than that of control group (p<0.05). Thus supplementation of tannic acid to high fat diet could be effective to reduce the serum lipid levels such as total cholesterol, high density lipoprotein-cholesterol and triglycerides which were regarded as to cause the cardiovascular diseases.

Comparison of hematological values of conventional pigs and transgenic pigs supressed in immune rejection response (일반돼지와 면역 거부반응이 억제된 형질전환돼지의 혈액 성상 비교)

  • Cho, Ara;Oh, Keon Bong;Roh, Jae-Hee;Jung, Young-Hun;Jung, Suk-Han;Kang, Myoung-Geum;Kim, Mi-Suk;Do, Yoon Jung;Oh, Sang-Ik;Kim, Eunju;Yoo, Jae Gyu;Choe, Changyong
    • Korean Journal of Veterinary Service
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    • v.42 no.4
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    • pp.193-200
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    • 2019
  • Blood test is a useful tool in establishing medical treatment for livestock. It provides information such as disease diagnosis, treatment effects, prognostic judgment, and health status. This study compared the value of erythrocytes and leukocytes among conventional, transgenic miniature, and transgenic conventional pigs aged six months to 24 months. Further, it analyzed the aspects of hematological value changes according to the pigs' ages. As a result, the number of red blood cells (RBC), which include hemoglobin, and hematocrit, and the number of white blood cells (WBC), which include neutrophils, and lymphocyte, were high among transgenic miniature pigs, compared with the conventional and transgenic conventional pigs. Conventional pigs showed similar values of RBC and WBC regardless of transgenesis. In comparing their age, the RBC decreased as the age increased compared with the pigs among all the three groups aged of 6~12 months. On the other hand, WBC and neutrophils showed no significant difference regardless of different ages among all the three groups. However, various counts in RBC and WBC were mostly found to be higher in each age in transgenic miniature pigs than in conventional and transgenic conventional pigs. The results of this study show that the values of RBC and WBC were generally higher in transgenic miniature pigs than in conventional and transgenic conventional pigs. Based on this research, hematological values can be widely used in diagnosing diseases or checking the health status of transgenic pigs that are used as disease models, organ transplant source and alike.

The Effects of Daeyoungjeon(DYJ) on the Hypothyroidism in Rats (대영전(大營前)이 흰쥐의 갑상선기능저하에 미치는 영향)

  • Cho, Chung-Sik;Kim, Du-Hui;Choi, Jeong-Sik;Kim, Cheol-Jung
    • The Korea Journal of Herbology
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    • v.22 no.4
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    • pp.35-43
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    • 2007
  • Objective : The aim was to study experimentally the effects of Daeyoungjeon(DYJ) on the hypothyroidism of rats induced by thiouracil. Methods : Spargue-Dawley rats were separated into four groups. Except normal group, the other three groups were treated with thiouracil 0.50g/kg/days for 30 days by oral administration. Among the three groups, one group was treated DYJ extract 0.75g/kg/days for 20 days separately. Another group was treated DYJ extract 1.50g/kg/days for 20 days separately. T3-uptake, T3, T4, TSH, hematological values, enzyme activity, total cholesterol, triglyceride and Na+ content change in the Serum of rats were measured after medication of solid extract of DYJ. Results : As a result of this study, in the serum T3-Uptake and T4 level, hematological values and sodium were increased in DYJ group compared to control group. The serum TSH, total cholesterol, triglyceride, enzyme activity and body weight were decreased in DYJ group compared to control group. Conclusion : According to the above results, it is suggested that DYJ is effective to cure hypothyroidism.

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The Effects of Danggwisaeyeoktang(當歸四逆湯) on the Hypothyroidism of Rat (당귀사역탕(當歸四逆湯)이 백서의 갑상선기능저하증에 미치는 영향)

  • Kim, Dae-Bok;Kim, Cheol-Jung;Cho, Chung-Sik
    • The Korea Journal of Herbology
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    • v.22 no.1
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    • pp.95-102
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    • 2007
  • Objectives : The aim was to study experimentally the effects of Danggwisaeyeoktang(當歸四逆湯) on the hypothyroidism of rats induced by thiouracil. Methods : Spargue-Dawley rat were separated into three groups. Except normal group, the other two groups were treated with thiouracil 50mg/kg/days for 30 days by oral administration. Among the two group, one group was treated DGSYT extract 0.54g/kg/days for 20 days separately. T3-uptake;, T3, T4, TSH, hematological values, enzyme activity, total cholesterol and Na+ content charge in the Serum of rats were measured after medication of solid extract of DGSYT. Result : As a result of this study, in the serum T3-Uptake and T4 level, hematological values and sodium were increased in DGSYT group compared to controls. The serum TSH, total cholesterol and body weight were decreased in DGSYT group compared to controls. Conclusion : According to the above results, it is suggested that DGSYT is effective to cure hypothyroidism.

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Effects of L-carnitine on the ovariectomized rat (L-carnitine이 난소가 제거된 흰쥐에 미치는 영향)

  • Chon, Seung-Ki
    • Korean Journal of Veterinary Service
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    • v.33 no.3
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    • pp.309-312
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    • 2010
  • This was conducted to determine the effects of body weight, organ weight, hematological values and biochemical parameters by L-carnitine in the ovariectomized (OVX) rats. The animals were divided into 4 groups. Intact group (n=10) received no treatment and operation. Sham group (n=10) received only sham operation and no treatment. OVX group (n=10) received operation and no treatment. OVX+Carn group (n=10) received operation and L-carnitine. Body weight was significantly lower in OVX+Carn group than in all other groups. Also, organ weight such as heart, liver, spleen and kidney was measured. The heart and spleen weight were significantly lower in the OVX+Carn group than in the Intact and Sham group. The liver weight in the OVX+Carn group was significantly differences in comparison with those in the other groups. Also, there was significantly differences in the organ weight of kidney between in the OVX+Carn group and in the other groups. The hematological values of WBC, RBC, MCV, MCH and MCHC were no significant differences in any other groups. The total cholesterol, triglyceride and high density lipoprotein decreased significantly in the OVX+Carn group as compared to those in the OVX group. But, there were no significant differences in low density lipoprotein in any other groups. We conclude that L-carnitine enhanced the body weight in the ovariectomized rats. Our findings suggest that L-carnitine may influence the process of absorption of fat in the ovariectomized rats.

Investigation of hematological analyses and major viral serum antibody titers in DongGyeongi (동경이의 혈액상 및 주요 바이러스 혈중 항체가 조사)

  • Choi, Seog-Gyu;Sung, Gi-Chang;Lee, Eun-Woo;Park, Chang-Eun
    • Korean Journal of Veterinary Service
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    • v.37 no.4
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    • pp.273-280
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    • 2014
  • Investigations of hematologic and canine distemper virus, parvovirus antibody titer for DongGyeongi were performed. This study was conducted to determine into feeding and management blood values on DongGyeongi. Blood samples were collected from 110 healthy dogs (male 60, female 50). The diagnostic virus disease and hematologic results were classified by age, sex, color. Although gender differences were not apparent, complete blood cell counts analyses were performed and analyzed accordingly. Statistically significant differences (P<0.05) specific to age (<2). Also, The canine distemper virus and parvovirus antibody titer were correlation to age dependent (P<0.05). In conclusion, data obtained from this study may be valuable as a standard for interpretation of the results in hematologic and major viral antibody titer analysis of DongGyeongi populations. For the management of DongGyeongi, the programs will be used for the epidemic disease prevention.

Devocalization of Dogs by Fixation of Vocal Cords and Vocal Processes (개에서 성대 및 성대돌기의 고정에 의한 무성술)

  • 정종태;원상철
    • Journal of Veterinary Clinics
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    • v.15 no.1
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    • pp.124-130
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    • 1998
  • This study was performed to evaluate the new surgical technique for debarking. Of the 8 mongrel dogs which underwent devocalization, 4 heads (group 1) received complete surgical removal of the vocal cords and another 4 heads (group 2) received fixation of vocal cords and vocal processes onto the thyroid cartilage. Volume of each dogs' voices was measured by a sound level meter(Function A) over 7 months at intervals of 10 days. All experimental animals'hematological values were measured before operation and postoperative at 2i 5 and 10 days. The changes of volume of dogs'voices and hematological values were analyzed by paired t-test. The volume in the dogs'voices in each group after operation was significantly lower than that before operation. At this results we detected that devocalizing effect was the same in each group. Postoperative volume of dogs'voices in group 1 had a tendency to increaser but group 2 had a tendency to decrease. The number of erythrocytes at 2 days after operation was significantly fewer than those before operation in group 1, but the group 2 did not have significant changes. The number of leukocytes at 2 days after operation significantly increased from those before operation in group 11 but the group 2 did not have significant changes. It was concluded that the new surgical technique, fixation of vocal cords and vocal processes onto the thyroid cartilages could be available for the devocalization of dogs and for the prevention of postoperative inflammation and blood loss.

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