• Title/Summary/Keyword: Heat of Fusion

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Dry-Heat Treatment Process for Enhancing Viral Safety of an Antihemophilic Factor VIII Concentrate Prepared from Human Plasma

  • Kim, In-Seop;Choi, Yong-Woon;Kang, Yong;Sung, Hark-Mo;Shin, Jeong-Sup
    • Journal of Microbiology and Biotechnology
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    • v.18 no.5
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    • pp.997-1003
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    • 2008
  • Viral safety is a prerequisite for manufacturing clinical antihemophilic factor VIII concentrates from human plasma. With particular regard to the hepatitis A virus (HAV), a terminal dry-heat treatment ($100^{\circ}C$ for 30 min) process, following lyophilization, was developed to improve the virus safety of a solvent/detergent-treated antihemophilic factor VIII concentrate. The loss of factor VIII activity during dry-heat treatment was of about 5%. No substantial changes were observed in the physical and biochemical characteristics of the dry-heat-treated factor VIII compared with those of the factor VIII before dry-heat treatment. The dry-heat-treated factor VIII was stable for up to 24 months at $4^{\circ}C$. The dry-heat treatment after lyophilization was an effective process for inactivating viruses. The HAV, murine encephalomyocarditis virus (EMCV), and human immunodeficiency virus (HIV) were completely inactivated to below detectable levels within 10 min of the dry-heat treatment. Bovine herpes virus (BHV) and bovine viral diarrhea virus (BVDV) were potentially sensitive to the treatment. However porcine parvovirus (PPV) was slightly resistant to the treatment. The log reduction factors achieved during lyophilization and dry-heat treatment were ${\geq}5.55$ for HAV, ${\geq}5.87$ for EMCV, ${\geq}5.15$ for HIV, 6.13 for BHV, 4.46 for BVDV, and 1.90 for PPV. These results indicate that dry-heat treatment improves the virus safety of factor VIII concentrates, without destroying the activity. Moreover, the treatment represents an effective measure for the inactivation of non-lipid-enveloped viruses, in particular HAV, which is resistant to solvent/detergent treatment.

Study on resonant electron cyclotron heating by OSXB double mode conversion at the W7-X stellarator

  • Adlparvar, S.;Miraboutalebi, S.;Kiai, S.M. Sadat;Rajaee, L.
    • Nuclear Engineering and Technology
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    • v.50 no.7
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    • pp.1106-1111
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    • 2018
  • Electromagnetic waves potentially have been used to heat overdense nuclear fusion plasmas through a double mode conversion from ordinary to slow extraordinary and finally to Electron Bernstein Wave (EBW) modes, OSXB. This scheme is efficient and has not any plasma density limit of electron cyclotron resonance heating due to cut-off layer. The efficiency of conversion depends on the isotropic launching angles of the microwaves with the plasma parameters. In this article, a two-step mode conversions of OSXB power transmission efficiency affected by the fast extraordinary (FX) loses at upper hybrid frequency are studied. In addition, the kinetic (hot) dispersion relation of a overdense plasma in a full wave analysis of a OSXB in Wendelstein 7X (W7-X) stellarator plasma has been numerically simulated. The influence of plasma dependent parameters such as finite Larmor radius, electron thermal velocity and electron cyclotron frequency are represented.

Strength Characteristics of Reduced Activation Ferritic Steel for Fusion Blanket by TIG Welding (핵융합로 블랭킷용 저방사화 철강재료 TIG 용접부의 강도특성)

  • ;;;A. Kohyama
    • Journal of Welding and Joining
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    • v.21 no.1
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    • pp.87-92
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    • 2003
  • JLF-1 steel (Fe-9Cr-2W-V-Ta), reduced activation ferritic steel, is one of the promising candidate materials for fusion reactor applications. Tensile properties of JLF-1 base metal and its TIG weldments has been investigated at the room temperature, $400^{\circ}C$ and $600^{\circ}C$. The tensile strength of base metal (JLF-1) showed the level between those of weld metal and the Heat Affected Zone (HAZ). When the test temperature was increased from room temperature to high temperature ($400^{\circ}C$ and $600^{\circ}C$), both strength and ductility decreased or base metal, weld metal and the HAZ. The longitudinal specimens of base metal represented similar strength and ductility at room temperature and high temperature, compared to those of transverse specimens. Little anisotropy for the rolling direction was observed in the base metal of JLF-1 steel.

Evaluation of Microstructural and Mechanical Properties of SA508 cl.3 Heat Affected Zone Produced by RPV Cladding

  • Lee, J.S.;Kim, I.S.;Kwon, S.C.
    • Proceedings of the Korean Nuclear Society Conference
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    • 2004.10a
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    • pp.867-868
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    • 2004
  • The maximum width of HAZ of SA508치.3 steel produced by overlay RPV cladding was approximately 10 mm and it was composed of variety of microstructures with various grain size and precipitates. In addition, along the weld fusion line there formed a heavy carbide precipitation zone in the width of $20{\sim}30\;{\mu}m$. 2. As the specimen sampling position approached to the weld fusion line, the increase in yield and tensile strength was approximately 90 and 40 MPa, respectively. Meanwhile, the plastic fracture strain reduced from 14 to 8 percent. 3. The lowest SP energy and the highest ductile to brittle transition temperature in the HAZ were observed at the coarse- and fine-grained HAZ.

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A Sensor Module Overcoming Thick Smoke through Investigation of Fire Characteristics (화재 특성 고찰을 통한 농연 극복 센서 모듈)

  • Cho, Min-Young;Shin, Dong-In;Jun, Sewoong
    • The Journal of Korea Robotics Society
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    • v.13 no.4
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    • pp.237-247
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    • 2018
  • In this paper, we describe a sensor module that monitors fire environment by analyzing fire characteristics. We analyzed the smoke characteristics of indoor fire. Six different environments were defined according to the type of smoke and the flame, and the sensors available for each environment were combined. Based on this analysis, the sensors were selected from the perspective of firefighter. The sensor module consists of an RGB camera, an infrared camera and a radar. It is designed with minimum weight to fit on the robot. the enclosure of sensor is designed to protect against the radiant heat of the fire scene. We propose a single camera mode, thermal stereo mode, data fusion mode, and radar mode that can be used depending on the fire scene. Thermal stereo was effectively refined using an image segmentation algorithm, SLIC (Simple Linear Iterative Clustering). In order to reproduce the fire scene, three fire test environments were built and each sensor was verified.

A Study on Creep Crack Growth Behavior of Weld Interface Crack (용접 계면균열의 크리프 균열성장 거동에 관한 연구)

  • 윤기봉;김광웅;정용근
    • Journal of Welding and Joining
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    • v.16 no.4
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    • pp.83-91
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    • 1998
  • Cracking problems which high temperature plant components suffer during long-term service, occur very often at welded locations. The crack occurs due to accumulated creep damage near fusion line or at heat affected zone (HAZ). However, most of the studies on creep crack growth behavior have been performed with matrix metal not wit welded metal due to the difficulty of interpreting the test results. In this study, creep crack growth rates were measured with C(T) specimens whose cracks were formed along the fusion line or HAZ. The measured crack growth rates were characterized by {TEX}$C_{t}${/TEX}-parameter derived for elastic-primary-secondary creeping material. Since contribution of primary creep was significant for the tested 1Cr-0.5Mo steel, its effect was carefully studied. Effects of crack tip plasticity and material aging were also discussed.

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A Study on the Fabrication of Heater based on Silicone Rubber (실리콘러버 기반의 히터제작에 관한 연구)

  • Jeong-Oh Hong;Jae Tack Hong;Shin-Hyeong Choi
    • Advanced Industrial SCIence
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    • v.2 no.2
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    • pp.9-15
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    • 2023
  • Since silicone rubber heaters are flexible, they can be directly attached or installed in objects to be heated even in flat, curved or three-dimensional shapes. Since the current heating method heats the entire object to be heated and raises it to a required temperature, ignoring areas or positions where heat is not required, partial intensive heating cannot be performed. When using multi-heating zones, rather than heating the entire object to be heated, only the parts that need heat are intensively heated according to the process, so it is possible to heat quickly by local location by applying different amounts of heat with a small amount of electric capacity to each place that needs heat, and heat energy can reduce. In this study, the temperature and heating time of the partially concentrated region in the multi-heating region structure are measured so that a uniform temperature or temperature difference occurs in the region requiring thermal fusion. In order to determine the optimal power density range and reduce capacitance, the safety of a silicon rubber heater manufactured with a multi-heating zone structure is investigated. If the silicon rubber heater is manufactured in a multi-heating method, the multi-intensive heating technology can be ideally applied to all heating processes.

Effect of Heat Treatment on the Physical Properties of LM PET Jacquard Fabrics (저융점 폴리에스터 자카드직물의 물성에 대한 열처리 효과)

  • Lee, Sun Young;Kim, Jeong Hwa;Kim, Eui Hwa;Lee, Jung Soon;Lee, Seung Goo
    • Textile Coloration and Finishing
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    • v.25 no.3
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    • pp.206-214
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    • 2013
  • There has been an increasing demand for high performance and energy-saving of blind. In order to develop the eco-friendly blind textiles, heat treatment process has been utilized for LM(Low Melting) polyester fabrics and the changes of the physical properties of the treated fabrics were examined according to temperature of heat treatment. Morphology, surface reflectance, contact angle, luster, thermal property and mechanical property of heat treated LM polyester fabrics were investigated. As results, morphology analysis of thermal treated fabrics confirmed that degree of fusion of LM polyester yarns improved with increase of temperature. Surface reflectance of thermal treated fabrics decreased with increase of temperature. Luster and contact angle of a water droplet on thermal treated fabrics increased slightly with increase of temperature. The mechanical properties of the fabrics by KES-FB system were found to be temperature-dependent and especially, bending and shear properties among them were highly related to temperature.

Characterization of Mechanical Properties in the Heat Affected Zones of Alloy 82/182 Dissimilar Metal Weld Joint (Alloy 82/182 이종금속 용접부 열영향부의 계계적물성치 파악)

  • Kim, Jin-Weon;Kim, Jong-Sung;Lee, Kyoung-Soo
    • Journal of the Korean Society of Safety
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    • v.23 no.6
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    • pp.28-33
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    • 2008
  • This paper presents the characteristics of mechanical properties within the heat affected zones(HAZs) of dissimilar metal weld joint between SA508 Gr.1a and F3l6 stainless steel(SS) with Alloy 82/182 filler metal. Tensile tests were performed using small-size specimens taken from the heat affected regions close to both fusion lines of weld, and the micro-structures were examined using optical microscope(OM) and transmission microscope(TEM). The results showed that significant gradients of the yield stress(YS), ultimate tensile stress(UTS), and elongations were observed within the HAZ of SA508 Gr.1a. This was attributed to the different microstructures within the HAZ developed during the welding process. In the HAZ of F316 SS, however, the welding effect dominated the YS and elongation rather than UTS. TEM micrographs demonstrated these characteristics of the HAZ of F316 SS was associated with a dislocation-induced strain hardening.

A Study on Estimation of Cooling Load for Effective Control of Ice Thermal Storage System (빙축열 시스템의 효율적인 제어를 위한 냉방부하 예측에 관한 연구)

  • Yoo, Seong-Yeon;Han, Kyu-Hyun;Lee, Je-Myo;Han, Seung-Ho
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.20 no.2
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    • pp.128-136
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    • 2008
  • It is necessary to estimate the cooling load of the next day for effective control of ice thermal storage system. In this paper, new methodology is proposed to estimate the cooling load using design parameters of building and predicted weather data. Only six input parameters such as sensible heat coefficient and constant, latent heat coefficient and constant, maximum and minimum temperature are necessary to obtain hourly distribution of cooling load for the next day. Two benchmarking buildings(hospital and research institute) are selected to validate the performance of the proposed method, and the estimated cooling loads in hourly and daily bases are calculated and compared with the measured data for E hospital. The estimated results show fairly good agreement with the measured data for both buildings.