• YAKHAK HOEJI
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• v.48 no.6
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• pp.369-373
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• 2004

We previously reported that Streptococcus pneumoniae capsule attached to the surface protein (JY-Pol) was protective to systemic pneumococcal infection. The JY -Pol antigen induced IgM, IgG, and IgA in mice and provoked cell-mediated immunity. In this current study, we investigated the effect of anti JY-Pol antiserun and monoclonal antibody C2 (Mab C2) specific for the JY-Pol antigen against the pneumococcal disease. Mice that were given the antiserum survived longer than mice that received antiserum pre-absorbed with S.pneumoniae cells or DPBS as a negative control. Heat-treated anti JY-Pol antiserum resulted in survival rates similar to intact fresh JY-Pol antiserum. Mab C2 isolated from JY-Pol-immunized mice also enhanced resistance of naive mice against the pneumococcal diseaser. This protection by Mab C2 appeared to be mediated by opsonization as determined in a RAW 264.7 monocyte/macrophage cell line. Epitope analysis showed that Mab C2 epitope consisted of glucuronic acid and glucose that blocked the interaction of JY-Pol to the C2. Taken together, these data indicate that the antiserum induced by the JY-Pol, a naturally pneumococcal conjugate formula, mediated the protection by passive transfer, which was confirmed by protective effect of Mab C2.

• Transactions of the Korean hydrogen and new energy society
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• v.19 no.3
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• pp.217-225
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• 2008

A new micro reformer system consisted of a micro reformer, a microcombustor and a micro evaporator was studied experimentally and computationally. In order to satisfy the primary requirements for designing the microcombustor integrated with a micro evaporator, i.e. stable burning in a small confinement and maximum heat transfer through a wall, the present microcombustor is simply cylindrical to be easily fabricated but two-staged (expanding downstream) to feasibly control ignition and stable burning. Results show that the aspect ratio and wall thickness of the microcombustor substantially affect ignition and thermal characteristics. For the optimized design conditions, a premixed microflame was easily ignited in the expanded second stage combustor, moved into the smaller first stage combustor, and finally stabilized therein. A micro reformer system integrated with a modified microcombustor based on the optimized design condition was fabricated. For a typical operating condition, the designed micro reformer system produced 22.3 sccm hydrogen (3.61 W in LHV) in an overall efficiency of 12%.

• 한국전산유체공학회:학술대회논문집
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• 2006.10a
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• pp.181-184
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• 2006

High-speed flight vehicle have various cavities. The supersonic cavity flow is complicated due to vortices, flow separation and reattachment, shock and expansion waves. The general cavity flow phenomena include the formation and dissipation of vortices, which induce oscillation and noise. The oscillation and noise greatly affect flow control, chemical reaction, and heat transfer processes. The supersonic cavity' flow with high Reynolds number is characterized by the pressure oscillation due to turbulent shear layer, cavity geometry, and resonance phenomenon based on external flow conditions, The resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. In the present study, we performed numerical analysis of cavities by applying the unsteady, compressible three dimensional Reynolds-Averaged Navier-Stokes(RANS) equations with the ${\kappa}-{\omega}$ turbulence model. The cavity model used for numerical calculation had a depth(D) of 15mm cavity aspect ratio(L/D) of 3, width to spanwise ratio(W/D) of 1.0 to 5.0. Based on the PSD(Power Spectral Density) and CSD(Cross Spectral Density) analysis of the pressure variation, the dominant frequency was analyized and compared with the results of Rossiter's Eq.

• Journal of computational fluids engineering
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• v.11 no.4 s.35
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• pp.62-66
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• 2006

High-speed flight vehicle have various cavities. The supersonic cavity flow is complicated due to vortices, flow separation, reattachment, shock waves and expansion waves. The general cavity flow phenomena includes the formation and dissipation of vortices, which induce oscillation and noise. The oscillation and noise greatly affect flow control, chemical reaction, and heat transfer processes. The supersonic cavity flow with high Reynolds number is characterized by the pressure oscillation due to turbulent shear layer, cavity geometry, and resonance phenomenon based on external flow conditions. The resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. In the present study, we performed numerical analysis of cavities by applying the unsteady, compressible three dimensional Reynolds-Averaged Navier-Stokes(RANS) equations with the ${\kappa}-{\omega}$ turbulence model. The cavity model used for numerical calculation had a depth(D) of 15mm cavity aspect ratio (L/D) of 3, width to spanwise ratio(W/D) of 1.0 to 5.0. Based on the PSD(Power Spectral Density) and CSD(Cross Spectral Density) analysis of the pressure variation, the dominant frequency was analyzed and compared with the results of Rossiter's Eq.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.19 no.2
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• pp.47-54
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• 2020

Themo-mechanical analysis was carried out using the finite element method for the steel shell of a cupola furnace. When the outer surface of the shell was cooled with water to within the temperature range of 35-80 ℃ during operation of the cupola, the inner surface of the shell was expected to exhibit a temperature of 65-248 ℃ based on heat transfer analysis. The shell was also expected to have an equivalent stress range of 100-280 MPa in the outer surface over the temperature range examined. Upon cooling the shell to obtain an outer surface temperature <80 ℃, the maximum equivalent stress of the shell did not exceed the yield strength. Although the temperature of the outer surface varied between 35 and 80 ℃ periodically due to the cooling control problem, the fatigue stress at the outer surface of the shell was calculated to be within the fatigue strength. During a non-operational period to examine the system between furnace operations, the thermal stress presented in the shell was sufficiently low to reach the desired yield strength and fatigue limit.

• Journal of Ocean Engineering and Technology
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• v.34 no.2
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• pp.110-119
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• 2020

Explosions and fires on offshore drilling units and process plants, which cause loss of life and environmental damage, have been studied extensively. However, research on drilling units increased only after the 2010 Deepwater Horizon accident in the Gulf of Mexico. A major reason for explosions and fires on a drilling unit is blowout, which is caused by a failure to control the high temperatures and pressures upstream of the offshore underwater well. The area susceptible to explosion and fire due to blowout is the drill floor, which supports the main drilling system. Structural instability and collapse of the drill floor can threaten the structural integrity of the entire unit. This study simulates the behavior of fire subsequent to blowout and assesses the thermal load. A heat transfer structure analysis of the drill floor was carried out using the assessed thermal load, and the risk was noted. In order to maintain the structural integrity of the drill floor, passive fire protection of certain areas was recommended.

• Journal of Drive and Control
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• v.13 no.3
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• pp.1-7
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• 2016

A cold gas blow-down hydraulic actuation system is widely used in missiles that require an actuation system with a fast response time under a limited space with a short operating time and large loads on the actuators. The system consists of a pneumatic part that supplies the regulated high-pressure gas to a reservoir, and a hydraulic part that supplies pressurized hydraulic oil to the actuators by the pressurized gas in the reservoir. This paper proposes a mathematical model to analyze and simulate the pneumatic part of an actuation system that supplies the operating power to the actuators. The mathematical model is based on the ideal gas equation and also considers the models for heat transfer. The model is applied to the pressure vessel and the gas part of the reservoir, and the model for the pneumatic part is established by connecting the two models for the parts. The model is validated through a comparison of the simulation results with the experimental results. The comparison shows that the suggested model could be useful in the design of the pneumatic part of a cold gas blow-down type hydraulic actuation system.

• Journal of computational fluids engineering
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• v.10 no.2
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• pp.48-53
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• 2005

This work discusses the numerical analysis, the design and experimental test of the SMA actuator along with its capabilities and limitations. Convective heating and cooling using water actuate the SMA(Shape memory alloy) element of the actuator. The fuel such as propane, having a high energy density, is used as the energy source for the SMA actuator in order to increase power and energy density of the system, and thus in order to obviate the need for electrical power supplies such as batteries. The system is composed of a pump, valves, bellows, a heater(burner), control unit and a displacement amplification device. The experimental test of the SMA actuator system results in 150 MPa stress(force : 1560 N) with $3\%$ strain and 0.5 Hz. actuation frequency. The actuation frequency is compared with the prediction obtained from numerical analysis. For the designed SMA actuator system, the results of numerical analysis were utilized in determining design parameters and operating conditions.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.23 no.5
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• pp.670-677
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• 1999

An analysis of generation and growth of multicomponent particles has been carried out to predict the size and composition distributions of particles generated in the Modified Chemical Vapor Deposition(MCVD) process. In MCVD process. scale-up of sintering and micro-control of refractive index may need the Information about the size and composition distributions of $SiO_2-GeO_2$ particles that are generated and deposited. The present work solved coupled steady equations (axi-symmetric two dimensions) for mass conservation, momentum balance. energy and species(such as $SiCl_4$, $GeCl_4$, $O_2$, $Cl_2$) conservations describing fluid flow. heat and mass transfer in a tube. Sectional method has been applied to obtain multi-modal distributions of multicomponent aerosols which vary in both radial and axial directions. Chemical reactions of $SiCl_4$ and $GeCl_4$ were included and the effects of variable properties have also been considered.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.40 no.3
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• pp.139-148
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• 2016

Thermodynamic analysis is conducted on the first-order approximation model for turbines and compressors. It is shown that the adiabatic efficiency could be greater than unity, depending on the entropic mean temperature, entropy generation, thermal reservoir temperature, and heat transfer. Therefore, adiabatic efficiency applied to a diabatic control volume results in an error overestimating its performance. To resolve this overestimation, it is suggested that a reversible diabatic process be referred to as an ideal process to evaluate diabatic efficiency. The diabatic efficiency suggested in this work is proven to always be less than unity and it is smaller than the exergy efficiency in most cases. The diabatic efficiency could be used as a more general definition of efficiency, which would include adiabatic efficiency.