• Title/Summary/Keyword: Heart development

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Experimental Techniques for Evaluating the Success of Restoration Projects

  • Robinson, George R.;Handel, Steven-N.l;Mattei, Jennifer
    • The Korean Journal of Ecology
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    • v.25 no.1
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    • pp.1-7
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    • 2002
  • The ecological background of a restoration project is complex and difficult to betermine without experimentation. A useful context for experiments is the well-studied process of natural succession, because the factors that drive or inhibit succession are also at work during reclamation (a form of primary succession) and restoration (which often resembles secondary succession). Using experimental studies on urban wasteland reclamation, we have tested for factors that stimulate or inhibit succession during early phases of woodland development in the Northeastern United states. The emphasis has been on mutualisms (seed dispersal, pollination, and mycorrhizae) and microsite limitations in the recruitment, growth, and reproduction of woody plants. Using plantings of seeds, seedlings, and clusters of reproductively mature plants on abandoned landfills, we have observed that (1) soil microsite deficiencies lead to very poor germination (<0.1$\%$) and seedling survival (<0.01$\%$) of most native species; (2) seed dispersal by birds is a significant and reliable source of woody plant recruitment; however (3) proximity effects are strong, with most (up to 95$\%$) of seed rain falling in the vicinity of planted clusters that are closest to putative seed sources; and (4) remnant natural woodlands are critical components of the recruitment process. To emphasize the last point, in one case, we found that the destruction of approximately 50$\%$ of nearby natural woodland vegetation led to a commensurate decline in seed rain. In another case, we found that the species richness of recruits was strictly limited by the species composition of nearby source plant communities, with no evidence of community enrichment by long distance dispersal over 5 years. We conclude from these results that the size and proximity of remnant natural populations are critical considerations when planning reclamation and restoration programs that rely on natural successional processes.

A study on the Medicines Effected on the Liver in the 'Bowel-Viscus Classification' of An Introduction to Medical Science ($\ll$의학입문(醫學入門).장부조분(臟腑條分)$\gg$간장(肝臟)에 작용하는 약물(藥物)에 관한 연구(硏究))

  • Keum, Kyung-Soo;Lim, Yang-Sun
    • Journal of the Korean Institute of Oriental Medical Informatics
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    • v.11 no.1
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    • pp.26-47
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    • 2005
  • In this dissertation, I will focus on the channel entry, the effect, and the treatment throughout books of oriental medicine from ancient to modern in order to classify the medicines of the liver as main or supplementary organ. The results are as follows: 1. The kinds of the medicines of working of the liver(本臟) were 29, which were Amydae carapax(鱉甲), Chrysanthemi Flos(菊花), Cassiae Torae Semen(草決明), Plantaginis Semen(車前子), Scirpi Seu Sparganii(三稜), Ulmi Pasta Semen(蕪荑), Cinnamomi Cortex(肉桂), Fraxini Cortex(秦皮), Chaenomelis Fructus(木果), Corii Asini Colla(阿膠), Chuanxiong Rhizoma(川芎), Adenophorae Radix(沙蔘), Coicis Semen(薏苡仁), Acanthopanacis Cortex(五加皮), Zizyphi Spinosae Semen(酸棗仁), Picrorrhizae Rhizoma(胡黃連), Gentianae Radix(草龍膽), Citri Reticulatae Virdie Pericarpium(靑皮), Paeoniae Alba Radix(白芍藥), Paeoniae Rubra Radix(赤芍藥), Bupleuri Radix(柴胡), Peucedani Radix(前胡), Naturalis Indigo(靑黛), Citrus unshiu(橘葉), Rhinocerotis Cornu(犀角), Aucklandiae Radix(木香), Polygonati Odorati Rhizoma, Farfarae Flos(款冬花), Evodiae Fructus(吳茱萸), Citri Reticulatae Pericarpium(陳皮) . 2. The kinds of the medicines of working of other viscera(他臟) were 7, which were Astragaliadix(黃耆), Ginseng Radix(人蔘), pinelliae Rhizoma(半夏), Myristicae Semen, Euryales Semen, Arecae Semen, Piperis Longi Fructus. 3. Medicines, effected on the heart functioned through any other viscera are as follows: Arecae Semen works to treat Spleen Gi Entering the Liver(脾氣入肝), Piperis Longi Fructus, pinelliae Rhizoma(半夏), Euryales Semen and Myristicae Semen operate to treat Spleen Cold Entering the Liver(脾冷入肝), Astragali Radix(黃耆) and Ginseng Radix(人蔘) work to treat Spleen Vacuity Entering the Liver(脾虛入肝). In the study of concerning the medicines effected on the liver, It is considered that it dedicated to development of the medicines related to the disease of the liver and making efficient use of the medicines.

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A study on investigation about the meaning and the research trend of computational thinking(CT) in mathematics education (수학교육에서 계산적 사고(Computational Thinking)의 의미 및 연구 동향 탐색)

  • Shin, Dongjo;Choi-Koh, Sangsook
    • The Mathematical Education
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    • v.58 no.4
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    • pp.483-505
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    • 2019
  • Across the world, there is a movement to incorporate computational thinking(CT) into school curricula, and math is at the heart of this movement. This paper reviewed the meanings of CT based on the point of view of Jeanette Wing, and the trend of domestic and international studies that incorporated CT into the field of mathematics education was analyzed to provide implications for mathematics education and future research. Results indicated that the meaning of CT, defined by mainly computer educators, varied in their operationalization of CT. Although CT and mathematical thinking generally have common points that are oriented toward problem solving, there were differences in the way of abstraction that is central to the two thinking processes. The experimental studies on CT in the field of mathematics education focused mainly on the development of students' cognitive capacities and affective domains through programming(coding). Furthermore, the previous studies were mainly conducted on students in school, and the studies conducted in the context of higher education, including pre-service and in-service teachers, were insufficient. Implications for mathematics teacher educators and teacher education as well as the relationship between CT and mathematical thinking are discussed.

Forecast of Land use Change for Efficient Development of Urban-Agricultural city (도농도시의 효율적 개발을 위한 토지이용변화예측)

  • Kim, Se-Kun;Han, Seung-Hee
    • Journal of Korean Society for Geospatial Information Science
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    • v.20 no.2
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    • pp.73-79
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    • 2012
  • This study attempts to analyze changes in land use patterns in a compound urban and agricultural city Kimje-si, using LANDSAT TM imagery and to forecast future changes accordingly. As a new approach to supervised classification, HSB(Hue, Saturation, Brightness)-transformed images were used to select training zones, and in doing so classification accuracy increased by more than 5 percent. Land use changes were forecasted by using a cellular automaton algorithm developed by applying Markov Chain techniques, and by taking into account classification results and GIS data, such as population of the pertinent region by area, DEMs, road networks, water systems. Upon comparing the results of the forecast of the land use changes, it appears that geographical features had the greatest influence on the changes. Moreover, a forecast of post-2030 land use change patterns demonstrates that 21.67 percent of mountain lands in Kimje-si is likely to be farmland, and 13.11 percent is likely to become city areas. The major changes are likely to occur in small mountain lands located in the heart of the city. Based on the study result, it seems certain that forecasting future land use changes can help plan land use in a compound urban and agricultural city to procure food resources.

Obstructive sleep apnea syndrome in children: Epidemiology, pathophysiology, diagnosis and sequelae

  • Chang, Sun-Jung;Chae, Kyu-Young
    • Clinical and Experimental Pediatrics
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    • v.53 no.10
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    • pp.863-871
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    • 2010
  • The prevalence of pediatric obstructive sleep apnea syndrome (OSAS) is approximately 3% in children. Adenotonsillar hypertrophy is the most common cause of OSAS in children, and obesity, hypotonic neuromuscular diseases, and craniofacial anomalies are other major risk factors. Snoring is the most common presenting complaint in children with OSAS, but the clinical presentation varies according to age. Agitated sleep with frequent postural changes, excessive sweating, or abnormal sleep positions such as hyperextension of neck or abnormal prone position may suggest a sleep-disordered breathing. Night terror, sleepwalking, and enuresis are frequently associated, during slow-wave sleep, with sleep-disordered breathing. Excessive daytime sleepiness becomes apparent in older children, whereas hyperactivity or inattention is usually predominant in younger children. Morning headache and poor appetite may also be present. As the cortical arousal threshold is higher in children, arousals are not easily developed and their sleep architectures are usually more conserved than those of adults. Untreated OSAS in children may result in various problems such as cognitive deficits, attention deficit/hyperactivity disorder, poor academic achievement, and emotional instability. Mild pulmonary hypertension is not uncommon. Rarely, cardiovascular complications such as cor pulmonale, heart failure, and systemic hypertension may develop in untreated cases. Failure to thrive and delayed development are serious problems in younger children with OSAS. Diagnosis of pediatric OSAS should be based on snoring, relevant history of sleep disruption, findings of any narrow or collapsible portions of upper airway, and confirmed by polysomnography. Early diagnosis of pediatric OSAS is critical to prevent complications with appropriate interventions.

Gata6 in pluripotent stem cells enhance the potential to differentiate into cardiomyocytes

  • Yoon, Chang-Hwan;Kim, Tae-Won;Koh, Seok-Jin;Choi, Young-Eun;Hur, Jin;Kwon, Yoo-Wook;Cho, Hyun-Jai;Kim, Hyo-Soo
    • BMB Reports
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    • v.51 no.2
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    • pp.85-91
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    • 2018
  • Pluripotent stem cell (PSC) variations can cause significant differences in the efficiency of cardiac differentiation. This process is unpredictable, as there is not an adequate indicator at the undifferentiated stage of the PSCs. We compared global gene expression profiles of two PSCs showing significant differences in cardiac differentiation potential. We identified 12 up-regulated genes related to heart development, and we found that 4 genes interacted with multiple genes. Among these genes, Gata6 is the only gene that was significantly induced at the early stage of differentiation of PSCs to cardiomyocytes. Gata6 knock-down in PSCs decreased the efficiency of cardiomyocyte production. In addition, we analyzed 6 mESC lines and 3 iPSC lines and confirmed that a positive correlation exists between Gata6 levels and efficiency of differentiation into cardiomyocytes. In conclusion, Gata6 could be utilized as a biomarker to select the best PSC lines to produce PSC-derived cardiomyocytes for therapeutic purposes.

Plant Regeneration via Somatic Embryogenesis and Organogenesis from Peucedanum japonicum $T_HUNB$ (갯기름나물의 체세포배 분화와 기관 분화를 통한 재분화)

  • Kim, Ok-Tae;Kim, Kwang-Soo;An, Jun-Chul;Hwang, Baik
    • Korean Journal of Plant Tissue Culture
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    • v.28 no.1
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    • pp.21-24
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    • 2001
  • Peucedanum japonicum $T_{HUNB}$ used as a edible and medicinal plants was investigated for in uitro regeneration. Callus formation occurred on leaf and stem explant cultures and showed spontaneous embryogenic and organogenic capability on MS basal medium supplemented with 0.1~5 mg/L NAA and 0~10 mg/L BA in dark. The regeneration was highest on the condition supplemented with 2.5 mg/L NAA and 10 mg/L BA. Development of the somatic embryo progressed through the globular, heart-shaped, torpedo-shaped and cotyledonary stage, typical of zygotic embryos. When the first somatic embryos was cultured on the medium supplemented with 0.2 mg/L NAA, secondary somatic embryo were induced with higher frequency on the hypocotyl then on the cotyledon and root.t.

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Positive and Negative Effects of IT on Cancer Registries

  • Mohammadzadeh, Niloofar;Safdari, Reza;Rahimi, Azin
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.7
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    • pp.4455-4457
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    • 2013
  • In the new millennium people are facing serious challenges in health care, especially with increasing non-communicable diseases (NCD). One of the most common NCDs is cancer which is the leading cause of death in developed countries and in developing countries is the second cause of death after heart diseases. Cancer registry can make possible the analysis, comparison and development of national and international cancer strategies and planning. Information technology has a vital role in quality improvement and facility of cancer registries. With the use of IT, in addition to gaining general benefits such as monitoring rates of cancer incidence and identifying planning priorities we can also gain specific advantages such as collecting information for a lifetime, creating tele medical records, possibility of access to information by patient, patient empowerment, and decreasing medical errors. In spite of the powerful role of IT, we confront various challenges such as general problems, like privacy of the patient, and specific problems, including possibility of violating patients rights through misrepresentation, omission of human relationships, and decrease in face to face communication between doctors and patients. By implementing appropriate strategies, such as identifying authentication levels, controlling approaches, coding data, and considering technical and content standards, we can optimize the use of IT. The aim of this paper is to emphasize the need for identifying positive and negative effects of modern IT on cancer registry in general and specific aspects as an approach to cancer care management.

A Study on Wearable Emergency Medical Alarm System (착용형 응급의료 경보시스템 구현에 관한 연구)

  • Kim, Dong-Wan;Beack, Seung-Hwa
    • Journal of IKEEE
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    • v.10 no.1 s.18
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    • pp.55-61
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    • 2006
  • In modern society, development of medical technology has extended the human life span. However, it has also caused some side-effects. Mostly old people who live alone are not available the medical service quickly when they are in emergency situations. Moreover heart related diseases as well are rapidly increasing with aging. This study proposes the emergency medical alarm system. This system measures the physiological signals such as ECG(electrocardiogram), temperature, and motion data, analyzes those data automatically, and sends the urgent message to the Emergency Medical Center and to their family. There are two main parts in the system. In the first part, physiological data acquisition part, the troublesome addition and deletion of body signals on existing proposed systems have been supplemented, which led to the modulized production by means of ECG sensor module, temperature sensor module, acceleration sensor module. The other part is mobile unit, which includes signal processing and transmission functions. And bluetooth allows two parts to communicate with each other. Data that are processed in the mobile unit are stored in the PC database through the WLAN using TCP/IP protocol.

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Development of Impedance Cardiograph and its Application (임피던스 심장기록기의 개발과 응용)

  • Kim, Deok-Won;Kim, Jeong-Yeol;Kim, Won-Ky;Park, Sang-Hui
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.27 no.3
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    • pp.54-62
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    • 1990
  • The thermodiluton is a standard method to measure cardiac output in clinical medicine. However it has many disadvantages such as expensive instrument and measurement, limited number of measurement, pain, safety problem, and side-effect due to insertion of catheter into heart. Electrical Impedance Cardiography has no such disadvantages and that it can continuously monitor stroke volume, contractility of cardiac muscle, and systolic time interval (STI) as well as cardiac output. While this impedance technique has been widely used and vigorously studied adroad, it is not introduced yet in Korea. Thus an Impedance Cardiograph has been developed in order to introduce this new technique. Its accuracy also has been verified by simultaneous measurement of cardiac output with the thermodilution technique. Finally changes of cardiac function during exercise were also measured.

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