• Title/Summary/Keyword: Healthy

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Functional annotation of de novo variants from healthy individuals

  • Lee, Jean;Hong, Sung Eun
    • Genomics & Informatics
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    • v.17 no.4
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    • pp.46.1-46.7
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    • 2019
  • The implications of germline de novo variants (DNVs) in diseases are well documented. Despite extensive research, inconsistencies between studies remain a challenge, and the distribution and genetic characteristics of DNVs need to be precisely evaluated. To address this issue at the whole-genome scale, a large number of DNVs identified from the whole-genome sequencing of 1,902 healthy trios (i.e., parents and progeny) from the Simons Foundation for Autism Research Initiative study and 20 healthy Korean trios were analyzed. These apparently nonpathogenic DNVs were enriched in functional elements of the genome but relatively depleted in regions of common copy number variants, implying their potential function as triggers of evolution even in healthy groups. No strong mutational hotspots were identified. The pathogenicity of the DNVs was not strongly elevated, reflecting the health status of the cohort. The mutational signatures were consistent with previous studies. This study will serve as a reference for future DNV studies.

Being healthy: Feeling healthy

  • Rastogi, Rajiv;Rastogi, Devesh
    • CELLMED
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    • v.8 no.1
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    • pp.1.1-1.4
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    • 2018
  • We have various understandings regarding health. Various medical systems being practiced in India other than conventional medicine i.e. Ayurveda, Yoga & Naturopathy, Unani, Siddha and Homoeopathy have defined health in their own way. From physical level up to spiritual level health has so many aspects which affect our overall personality. Some says that one who is established in self is healthy but some other says that in a perfect state of health physical homeostasis and mental equanimity occur in a balanced and healthy harmony. Another concept believes that health is normal and harmonious vibration of the elements and forces composing the human entity on the physical, mental, moral and spiritual planes of living in accordance with the constructive principles in Nature. At one place it is stated that good health means existence in harmony with evolution. The authors have reviewed various concepts and definitions of health and trying to conclude that health is a feeling which may be experienced only if you are really healthy. So, health is more and more balancing of all elements of your life in harmony with the universe.

The Comparison of Weight Distribution between the Healthy Persons and Low Back Pain Patients during Standing Posture (똑바로 선 자세에서 정상인과 요통환자의 체중분배에 관한 비교)

  • Kwon Mi-Ji;HwangBo Gak;Kim Jin-Sang
    • The Journal of Korean Physical Therapy
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    • v.5 no.1
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    • pp.9-15
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    • 1993
  • The purpose of this study was to describe the difference of weight distribution between healthy persons and low back pain patients during normal standing posture and to help the evaluation of weight bearing. 30 healthy persons and 30 low back pain patients being treated as hospitals in Taegu area participated in this study. The results were 2.63kg id the difference of weight distribution of healthy group and 3.04kg in low back pain group. This study was not significantly different between healthy and low back pain group.

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Postural Stability Change in Young People with Low Back Pain

  • Lee, Gyu-Chang
    • The Journal of Korean Physical Therapy
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    • v.24 no.3
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    • pp.181-185
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    • 2012
  • Purpose: We investigated balance change in patients with low back pain (LBP) by comparing postural sway velocity between young LBP patients and healthy subjects. Methods: The cross-sectional study enrolled 37 young patients with over 3-month duration of LBP and 38 healthy subjects between the ages of 20 and 30 years old. All subjects were targeted by measuring their balance during quiet standing with open eye and closed eye conditions. The postural sway velocity between the LBP patients and healthy subjects was compared. As well, postural sway velocity was determined in the LBP patients with both eyes open and closed. Results: Significant differences were evident in the anteroposterior and mediolateral mean velocity of center-of-pressure between LBP patients and healthy subjects, and in LBP patients in the eye open and eye closed conditions. Conclusion: The balance of young LBP patients was worse than healthy subjects during quiet standing, and was especially lessened in the absence of vision.

An Analysis of 'Family Constitution' and the Development Plan for the 'Making Family Constitution' Project in Healthy Family Support Centers : With a Focus on Healthy Family Support Centers in Seoul (건강가정지원센터 '가정헌법 만들기' 사업의 '가정헌법' 분석과 발전방안 : 서울 지역 건강가정지원센터를 중심으로)

  • Lee, Eun-Joo;Jun, Mi-Kyung
    • Journal of Families and Better Life
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    • v.31 no.2
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    • pp.93-108
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    • 2013
  • This study aimed to analyze the functionality and healthiness of family rules through a relational analysis of the relationship between the rule frequency by sub-family system and the content properties shown in the 'family constitution', It also aimed to examine the relationship between the perception degree of healthy family elements and the family subsystem rules and prepare the project development plans. As a result, it was a found that there were many dysfunctional rules, and healthiness was not satisfied. Project development plans include specific project plans, delivery systems, an orientation for practitioners, the necessity of evaluation and feedback, family health diagnosis, association with other project areas, and small scale operations.

Healthy Lifestyle of Pregnant Women (임부의 건강생활 양식)

  • Kim, Young-Hee
    • Korean Parent-Child Health Journal
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    • v.11 no.1
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    • pp.3-14
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    • 2008
  • Purpose: This study was to investigate the healthy lifestyle of women during pregnant. Method: This study reviewed the preceding researches related to pregnant women's healthy lifestyle through websites, articles, and books. Result: To promote healthy and pleased pregnancies, pregnant women were encouraged to get early and regular prenatal care. It included information, education, and counseling about how to handle special arrangements for pregnancy: weight gain, drug, smoking, alcohol, exercise, air travel, dental care, maternity clothes, vaccination, sex during pregnancy, workplace, hair treatment, hot tubs & saunas. Conclusion: Prenatal visits gave expected woman and partner chances to increase self-care and performance of a healthy lifestyle and then reduced the risk of having pregnancy-related complications.

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A Study on the Eating Habit and a Healthy Diet's Perception of Korean Food Investigated through a Focus Group Interview (FGI) - Focus on the Dietary Life Related Expert - (FGI(Focus Group Interview)를 통한 한국음식의 건강성인지 및 식태도에 관한 연구 - 식생활 관련 전문가들을 중심으로 -)

  • Chung, Hea-Jung;Kwon, Yong-Suk
    • Korean Journal of Human Ecology
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    • v.19 no.6
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    • pp.1115-1125
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    • 2010
  • This study investigated how Korean food is perceived within a healthy diet and what kinds of eating habits Korean people have. A Focus Group Interview (FGI) was conducted with participants who were experts on diet. Data were categorized into five groups using content analysis. categories were as follows: 1) Korean food and health assessment, 2) opinion on Koreans' current eating habits, 3) characteristics of Korean food, 4) comparison of Korean food in the past and present, 5) a plan for healthy diet. Results showed that a healthy diet should not only include a lot of vegetables, simple and unprocessed food as well as less spicy food, but that it should also be well-balanced nutritionally.

The Knee Joint Position Sense in Healthy Women (정상 성인 여성의 무릎관절 위치감각)

  • Yang, Kyung-Hye;Lee, Hyun-Ok
    • PNF and Movement
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    • v.8 no.1
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    • pp.31-39
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    • 2010
  • Purpose : The purpose of this study is to ascertain whether age, body mass index(BMI) and exercise frequency(EF) are correlated with knee joint position sense in healthy women. Methods : Healthy women of 150 who participated in this study were tested knee joint position sense; each reposition error was analyzed according to the age, BMI and EF. Reposition error was measured with a Myrin goniometer. Results : The age groups, BMI groups and EF groups demonstrated significant differences of the knee joint position sense. The older the healthy women are, the higher BMI is, and the lower EF is, the more decreased knee joint position sense has become. Conclusion : The older the women are, the higher BMI is, and the lower EF is, the more decreased the knee joint position sense in healthy women is. Therefore it needs to be considered to require management of obesity and regular exercise for prevention of knee injuries due to decreased joint position sense.

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Comparison of health-related outcome measured: Time-tradeoff measures vs. Healthy years equivalents (다속성 의사결정 이론을 토대로 한 삶의 질 측정치에 대한 이론적, 실험적 비교)

  • Lee, Seog-Jun
    • IE interfaces
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    • v.13 no.2
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    • pp.273-280
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    • 2000
  • Time-tradeoff measures and healthy years equivalents were assessed and compared through an empirical study based on Multi-attribute utility theory. The study included 33 student subjects as a pilot study, and 54 end-stage renal disease patients in Wisconsin. The two outcome measures were compared with the survival duration of 1, 5, and 10 years. The results of the study show that the time-tradeoff method and the two-stage method did not lead to the same numerical quantities, although they aim to measure the same quantities (equivalent numbers of healthy years) theoretically. The healthy years equivalents involved more inconsistencies, and were less reliable than the time-tradeoff measures. Overestimation of the healthy years equivalents was observed. This seemed to be caused by the complex procedure of the two-stage method as well as by the preferences assessment biases. Based on the study experiences, the time-tradeoff measure would be recommended for problems involving generic medical applications and health policies.

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Time Management Strategy for Healthy Family (건강가정을 위한 시간관리전략)

  • Chae, Ock-Hi;Ha, Young-Sook
    • Korean Journal of Human Ecology
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    • v.8 no.4
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    • pp.37-56
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    • 2005
  • With the recently increasing need for more theoretical approach on family resources aiming healthy family in the society, this study is to emphasize how important time, a personal resource, means for a healthy family and to seek how effectively time can be managed by referring to some documents. The followings are to be suggested in order for anyone to be able to apply by oneself to achieve a healthy family. First, time should be planned minute by minute. Second, prioritization should be done. Third, deadline should be made. Fourth, day planner and keeping a journal on it are recommended.

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