• Journal of the Korea institute for structural maintenance and inspection
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• v.14 no.1
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• pp.165-174
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• 2010

In this paper, a two-phase structural health monitoring system using acceleration response signatures are presented to firstly alarm the change in structural condition and to secondly detect the changed location for full-scale concrete girder bridges. Firstly, Mihocheon Bridge which is a two-span continuous concrete girder bridge is selected as the target structure. The dynamic response features of Mihocheon Bridge are extracted by forced vibration test using bowling ball. Secondly, the damage alarming occurrence and the damage localization techniques are selected to design two-phase structural health monitoring system for Mihocheon Bridge. As the damage alarming techniques, auto-regressive model using time-domain signatures, correlation coefficient of frequency response function and frequency response ratio assurance criterion are selected. As the damage localization technique, modal strain energy-based damage index method is selected. Finally, the feasibility of two-phase structural health monitoring systems is evaluated from static loading tests using a dump truck.

• Journal of Korean Society of Water and Wastewater
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• v.35 no.5
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• pp.335-349
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• 2021

As the frequency of seismic disasters in Korea has increased rapidly since 2016, interest in systematic maintenance and crisis response technologies for structures has been increasing. A data-based leading management system of Lifeline facilities is important for rapid disaster response. In particular, the water supply network, one of the major Lifeline facilities, must be operated by a systematic maintenance and emergency response system for stable water supply. As one of the methods for this, the importance of the structural health monitoring(SHM) technology has emerged as the recent continuous development of sensor and signal processing technology. Among the various types of SHM, because all machines generate vibration, research and application on the efficiency of a vibration-based SHM are expanding. This paper reviews a vibration-based pipeline SHM system for seismic disaster response of water supply pipelines including types of vibration sensors, the current status of vibration signal processing technology and domestic major research on structural pipeline health monitoring, additionally with application plan for existing pipeline operation system.

• Molecules and Cells
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• v.46 no.4
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• pp.191-199
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• 2023

The Golgi apparatus modifies and transports secretory and membrane proteins. In some instances, the production of secretory and membrane proteins exceeds the capacity of the Golgi apparatus, including vesicle trafficking and the post-translational modification of macromolecules. These proteins are not modified or delivered appropriately due to the insufficiency in the Golgi function. These conditions disturb Golgi homeostasis and induce a cellular condition known as Golgi stress, causing cells to activate the 'Golgi stress response,' which is a homeostatic process to increase the capacity of the Golgi based on cellular requirements. Since the Golgi functions are diverse, several response pathways involving TFE3, HSP47, CREB3, proteoglycan, mucin, MAPK/ETS, and PERK regulate the capacity of each Golgi function separately. Understanding the Golgi stress response is crucial for revealing the mechanisms underlying Golgi dynamics and its effect on human health because many signaling molecules are related to diseases, ranging from viral infections to fatal neurodegenerative diseases. Therefore, it is valuable to summarize and investigate the mechanisms underlying Golgi stress response in disease pathogenesis, as they may contribute to developing novel therapeutic strategies. In this review, we investigate the perturbations and stress signaling of the Golgi, as well as the therapeutic potentials of new strategies for treating Golgi stress-associated diseases.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2459-2465
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• 2012

Background: Numbers of epidemiological studies assessing residential radon exposure and risk of lung cancer have yielded inconsistent results. Methods: We therefore performed a meta-analysis of relevant published case-control studies searched in the PubMed database through July 2011 to examine the association. The combined odds ratio (OR) were calculated using fixed- or random-effects models. Subgroup and dose-response analyses were also performed. Results: We identified 22 case-control studies of residential radon and lung cancer risk involving 13,380 cases and 21,102 controls. The combined OR of lung cancer for the highest with the lowest exposure was 1.29 (95% CI 1.10-1.51). Dose-response analysis showed that every 100 Bq/$m^3$ increment in residential radon exposure was associated with a significant 7% increase in lung cancer risk. Subgroup analysis displayed a more pronounced association in the studies conducted in Europe. Studies restricted to female or non-smokers demonstrated weakened associations between exposure and lung cancer. Conclusions: This meta-analysis provides new evidence supporting the conclusion that residential exposure to radon can significantly increase the risk of lung cancer in a dose-response manner.

• The Korean Journal of Rehabilitation Nursing
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• v.9 no.2
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• pp.145-152
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• 2006

Purpose: The purpose of this study was to investigate the depression, anxiety, stress response and self-care, to analyze the correlation among depression, anxiety, stress response and self-care by gender, and to determine factors associated with self-care in diabetic patients. Method: The subjects of this study were 103 participants with diabetes mellitus. Data were analyzed by chi-square test, t-test, Pearson correlation coefficient and multiple regression analysis by using SAS program. Result: Items for self-care evaluation by gender were significant differences in hospital visit, hypoglycemia preparation, proper hygiene, taking a rest, foot injury check, drinking, and smoking. The female patients are more likely to have higher self-care score than the male patients. However, there were no differences in depression, anxiety and stress response by gender. In male patients, there were positive correlations between the degree of depression and stress response, the degree of anxiety and stress response. In female patients, there were positive correlations between the degree of depression and stress response, the degree of anxiety and stress response. In multiple regression analysis, gender and experienced admission is associated with self-care. Conclusion: We should consider integrated approaches for psychological problems in the management of diabetic patients.

• Korean Journal of Health Education and Promotion
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• v.29 no.2
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• pp.71-81
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• 2012

Objectives: Effective and efficient response for public health crisis necessitate planning how to respond and mobilize the resources in schools. We preformed this study to develop the strategies to improve efficiency of school health education in an outbreak of pandemic disease. Methods: We tried to review the policies, regulations and response systems of all related sectors, and advanced cases associated with pandemic disease control measures by searching databases and on-line networks connected with the Korean Ministry of Education, Science and Technology. Results: It was important to implement a consistent and systematic approach for educational offices and schools to prevent confusion resulted from the inaccurate information. First, the systems and action plans for school health should be established to prepare and respond to an outbreak of pandemic disease. Secondly, the strategies to improve the efficiency of school health education in public health crisis should be in place. Finally, the personnel pool would be needed to provide the crisis management programs. Conclusion: In order for staffs and students to have abilities to respond in an outbreak of pandemic disease, comprehensive school health approaches and efficient educational efforts should be prepared in collaboration with related sectors.

• 대한예방의학회:학술대회논문집
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• 1994.02a
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• pp.405-411
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• 1994

Hazardous wastes released into the general environment are of concern to the public and to public health authorities. In response to this concern, the Comprehensive Environmental Response, Compensation, and Liability Act, as amended (commonly called Superfund), was enacted in 1980 to provide a framework for environmental, public health, and legal actions concerning uncontrolled releases of hazardous substances. The Agency for Toxic Substances and Disease Registry (ATSDR) was created by Superfund to address the public health issues of hazardous wastes in the community environment. Two key Agency programs, Public Health Assessments and Toxicological Profiles, are designed to assess the risk to human health of exposures to hazardous substances that migrate from waste sites or through emergency releases (e.g., chemical spills). The Agency's public health assessment is a structured process that permits ATSDR to identify which waste sites or other point sources require traditional public health actions (e.g.. human exposure studies, health studies, registries, health surveillance, health advisories). The ATSDR qualitative public health assessment complements the U.S. Environmental Protection Agency's quantitative risk assessment. For Superfund purposes, both assessments are sitespecific. ATSDR's toxicological profiles are prepared for priority hazardous substances found most frequently at Superfund sites. Each profile presents the current toxicologic and human health effects information about the substance being profiled. Each profile also contains Minimal Risk Levels (MRLs), a type of risk assessment value. This paper covers ATSDR's experience in conducting public health assessments and developing MRLs, and it relates this experience to recommendations on how to improve chemical risk assessments.

• Journal of Korean Biological Nursing Science
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• v.24 no.1
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• pp.67-76
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• 2022

Purpose: The purpose of this study was to find stress mediation strategies for pandemic task forces in the future by identifying role stress experienced by local officials in public health centers working as COVID-19 response task force. Whether they suffered from trauma and post-traumatic stress disorder (PTSD) due to COVID-19 was also determined. Methods: Subjects for this research were 185 public health center workers in 7 northern Gyeonggi cities with at least three months of COVID-19 response task force experience. The investigation lasted for two months, from February to March of 2021. Data were collected using a self-administered questionnaire. Results: The average role stress of research subjects was 2.79±0.60. There were 64 subjects (34.6%) who answered 'yes' for trauma experience due to COVID-19. Subjects' role stress by sociodemographic and role characteristics displayed statistically significant differences in gender (t = -2.74, p= .007), age (F = 6.41, p= .002), profession (F = 0.01, p= .014), and COVID-19 response task (F= 3.01, p= .019). Specifically, role stress was higher for females than for males, those who were in their 20's (than 40's), a nursing profession (rather than others). Role stress was also higher in COVID-19 confirmed response work or in a self-quarantine work. There was a significant difference in trauma according to COVID-19 response roles (χ² = 26.59, p= < .001) and other tasks given or not (χ²= 9.48, p= .002). Conclusion: It is necessary to take measures to reduce COVID-19 response task force's role stress and trauma.

• Journal of Korean Clinical Health Science
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• v.8 no.1
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• pp.1362-1368
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• 2020

Purpose. In this study, The change of the accommodation function due to the use of a smartphone was objectively evaluated using an Auto Refractokeratometer and was to investigate the effect of accommodation response and microfluctuations of accommodation on stable fatigue. Methods. Twenty subjects (20 males, 20 females) who had no abnormalities in ophthalmic disease and strabismus, diplopia, suppression, convergence and ocular movement, and corrected visual acuity and unaided visual acuity of 0.8 or more were performed. The average age of the participants is (21.78 ± 1.78) years old. The refractive power of the eye was measured using an Auto Refractokeratometer (Speedy-i K-model, Righton Mfg Co. Tokyo Japan), and the equivalent spherical power was automatically calculated from the measured refractive power. The accommodation response amount was calculated for the accommodation stimulation amount in 8 steps in 0.5D increments from + 0.50D to -3.00D in the calculated equivalent spherical power. The microfluctuations of accommodation in the high frequency region was calculated according to the change in the amount of the accommodation stimulus. At this time, the spectral power of the microfluctuations of accommodation was analyzed by Fast Fourier Transformation (FFT). Results. After using the smartphone, it was found that the accommodation response to accommodation stimulation decreased and the microfluctuations of accommodation increased. Conclusions. It can be said that the use of a smartphone affects the accommodation response and the microfluctuations of accommodation, thereby causing a accommodative stable fatigue. Therefore, it is thought that the use of a smartphone for a long time may bring about a change in the accommodation function.

• Safety and Health at Work
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• v.4 no.2
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• pp.111-116
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• 2013

Background: The aim of this study was to evaluate the quality of the Second Korean Working Conditions Survey (KWCS), focusing on its validity and reliability. Methods: The external validity was evaluated by the assessment of sampling procedures and the response rate, in order to investigate the representativeness of the sample. The content validity was evaluated by the assessment of the development of the questionnaire, and the consistency of questions for the selected construct. The test-retest method was used to evaluate the reliability by means of a phone call survey of 30% of the respondents, who were randomly selected. The respondents' satisfaction regarding the survey procedures and interview time were analyzed to evaluate the quality of survey data. Results: The external validity was assured by an acceptable sampling procedure, rigid multi-stage stratified cluster random sampling. The content validity was also guaranteed by a reasonable procedure for the development of the questionnaire with a pretest. The internal consistency of the questions for work autonomy was maintained, with 0.738 of Cronbach's alpha. The response rate of 36% was lower than that of the European Working Conditions Survey (EWCS), with a contact rate of 66%, compared to 76% for the EWCS. The matching rates of the five retested questions were more than 98% reliable. Conclusion: The quality of the second KWCS was assured by the high external and content validity and reliability. The rigid sampling procedure and development of the questionnaire contributed to quality assurance. The high level of reliability may be guaranteed by the sophisticated field survey procedures and the development of a technical manual for interviewers. The technical strategies for a high response rate should be developed for future surveys.