• 제목/요약/키워드: Health research and development

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Cancer Registration in India - Current Scenario and Future Perspectives

  • Chatterjee, Sharmila;Chattopadhyay, Amit;Senapati, Surendra Nath;Samanta, Dipti Rani;Elliott, Leslie;Loomis, Dana;Mery, Lesly;Panigrahi, Pinaki
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권8호
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    • pp.3687-3696
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    • 2016
  • Cancer registration, an important component of cancer surveillance, is essential to a unified, scientific and public health approach to cancer prevention and control. India has one of the highest cancer incidence and mortality rates in the world. A good surveillance system in the form of cancer registries is important for planning and evaluating cancer-control activities. Cancer registration in India was initiated in 1964 and expanded since 1982, through initiation of the National Cancer Registry Program (NCRP) by the Indian Council of Medical Research. NCRP currently has twenty-six population based registries and seven hospital based registries. Yet, Indian cancer registries, mostly in urban areas, cover less than 15% of the population. Other potential concerns about some Indian registries include accuracy and detail of information on cancer diagnosis, and timeliness in updating the registry databases. It is also important that necessary data collection related quality assurance measures be undertaken rigorously by the registries to ensure reliable and valid information availability. This paper reviews the current status of cancer registration in India and discusses some of the important pitfalls and issues related to cancer registration. Cancer registration in India should be complemented with a nationwide effort to foster systematic investigations of cancer patterns and trends by states, regions and sub populations and allow a continuous cycle of measurement, communication and action.

Development of a chatbot for school violence prevention among elementary school students in South Korea: a methodological study

  • Kyung-Ah Kang;Shin-Jeong Kim;Byoung-doo Oh;Yu-Hyeon Kim
    • Child Health Nursing Research
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    • 제30권1호
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    • pp.45-53
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    • 2024
  • Purpose: This study develops a chatbot for school violence prevention (C-SVP) among elementary school students. Methods: Among the analysis, design, development, implementation, and evaluation (ADDIE) models, ADD phases were applied to develop a C-SVP. Students' learning needs were identified by constructing content with a design that attracted their attention. Subsequently, a formative evaluation was conducted on the developed C-SVP to test its applicability by ten elementary school students targeting the 5th and 6th grades. Results: The chatbot was designed using KakaoTalk and named "School Guardian Angel." The formative evaluation revealed that the developed C-SVP was easily accessible and useful for elementary school students. Conclusion: The developed C-SVP is expected to be effective in preventing violence among elementary school students. However, further research involving children of various age groups is required.

주요 국가의 화장품규정과 비교한 우리나라의 화장품법령 개정방안 (Cosmetic Regulation in Main Countries and Its Development Strategy in Korea)

  • 김영찬;황순욱;김대중
    • 대한화장품학회지
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    • 제31권1호
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    • pp.1-11
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    • 2005
  • 유럽연합, 미국, 일본을 중심으로 한 주요 국가의 화장품 관리규정의 변화를 주요 이슈별로 비교 검토하여 이를 토대로 우리나라의 화장품 법령의 개정방향을 제시하였다. 이들 비교 대상국가에서는 화장품 산업의 발전과 소비자의 안전확보를 위하여 사후관리체계를 강화하고 있다. 우리나라의 경우 화장품 인정범위의 확대, 표시${\cdot}$광고의 개선, 전성분표시제, 사용기한 표시등의 단계적 도입이 필요하며, 업체 자율책임과 사후관리체계로의 전환을 위하여 화장품 GMP의 도입$\cdot$ 확대를 위한 지원정책의 수립이 필요하다고 판단된다.

Effect of feeding raw potato starch on the composition dynamics of the piglet intestinal microbiome

  • Yi, Seung-Won;Lee, Han Gyu;So, Kyoung-Min;Kim, Eunju;Jung, Young-Hun;Kim, Minji;Jeong, Jin Young;Kim, Ki Hyun;Oem, Jae-Ku;Hur, Tai-Young;Oh, Sang-Ik
    • Animal Bioscience
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    • 제35권11호
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    • pp.1698-1710
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    • 2022
  • Objective: Raw potato starch (RPS) is resistant to digestion, escapes absorption, and is metabolized by intestinal microflora in the large intestine and acts as their energy source. In this study, we compared the effect of different concentrations of RPS on the intestinal bacterial community of weaned piglets. Methods: Male weaned piglets (25-days-old, 7.03±0.49 kg) were either fed a corn/soybean-based control diet (CON, n = 6) or two treatment diets supplemented with 5% RPS (RPS5, n = 4) or 10% RPS (RPS10, n = 4) for 20 days and their fecal samples were collected. The day 0 and 20 samples were analyzed using a 16S rRNA gene sequencing technology, followed by total genomic DNA extraction, library construction, and high-throughput sequencing. After statistical analysis, five phyla and 45 genera accounting for over 0.5% of the reads in any of the three groups were further analyzed. Furthermore, short-chain fatty acids (SCFAs) in the day 20 fecal samples were analyzed using gas chromatography. Results: Significant changes were not observed in the bacterial composition at the phylum level even after 20 d post feeding (dpf); however, the abundance of Intestinimonas and Barnesiella decreased in both RPS treatment groups compared to the CON group. Consumption of 5% RPS increased the abundance of Roseburia (p<0.05) and decreased the abundance of Clostridium (p<0.01) and Mediterraneibacter (p< 0.05). In contrast, consumption of 10% RPS increased the abundance of Olsenella (p<0.05) and decreased the abundance of Campylobacter (p<0.05), Kineothrix (p<0.05), Paraprevotella (p<0.05), and Vallitalea (p<0.05). Additionally, acetate (p<0.01), butyrate (p<0.05), valerate (p = 0.01), and total SCFAs (p = 0.01) were upregulated in the RPS5 treatment group Conclusion: Feeding 5% RPS altered bacterial community composition and promoted gut health in weaned piglets. Thus, resistant starch as a feed additive may prevent diarrhea in piglets during weaning.

걸음마기 아동의 정신건강 위험요인 선별척도의 개발 및 타당화 (The Development and Validation of a Scale for the Mental Health Screening of Toddlers)

  • 이정화;이소희
    • 아동학회지
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    • 제27권2호
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    • pp.195-213
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    • 2006
  • Development of the 3 scales comprising the present research was based on review of literature, existing screening scales, and empirical research pertaining to (Scale I) the development of social and emotional problems of children, (Scale II) parent-child relations, and (Scale III) assessment of children's environment. Professionals in each area approved a draft of the new screening scale. The clinical group was classified into normal and at-risk groups based on the Denver II scale and the Child Behavior Check List(ages 1.5-5). The clinical groups were administered the newly developed screening scale to see whether the same classification pertained. Results proved the cross-validity of the new scale.

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일 지역 고등학생의 암에 대한 지식, 태도 및 암 예방 건강행위 (The Relationships of Knowledge, Attitudes about Cancer and Health Behavior for Cancer Prevention in High School Students)

  • 김영숙
    • Child Health Nursing Research
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    • 제16권2호
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    • pp.102-111
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    • 2010
  • Purpose: This study was conducted to identify high school students' knowledge and attitude about cancer, and to examine the relation between these variables. Methods: The participants were 811 students from 8 high schools in U city. The data were analyzed using Pearson correlation coefficients, ANOVA and Duncan test with SPSS/WIN 12.0. Results: The score for participants' knowledge about cancer was 18.88 out of a possible 30, and their score for attitude towards cancer was 34.74 points of a possible 50. There were significant differences in knowledge about cancer according to gender, religion, school grades and worries about cancer. The attitude towards cancer showed significant differences according to worries about cancer and family atmosphere. The health behaviors were also statistically affected by factors like whether one smoked or not, health condition and harmony of family life. There was a significant positive correlation between attitude towards cancer and health behavior for cancer prevention. Attitude towards cancer and health behavior for cancer prevention showed a positive correlation with knowledge about cancer. Conclusion: The results of this study indicate that the development of an appropriate attitude towards cancer by high school students should lead to the practice of health behavior to prevent cancer. This development could be enhanced with structured and on-going education about cancer.

Towards Elimination of Asbestos-Related Diseases: A Theoretical Basis for International Cooperation

  • Takahashi, Ken;Kang, Seong-Kyu
    • Safety and Health at Work
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    • 제1권2호
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    • pp.103-106
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    • 2010
  • We develop a theoretical framework for international cooperation that can be used for the elimination of asbestos-related diseases(ARDs). The framework is based on the similarities in the temporal patterns of asbestos use and occurrence of ARDs in diverse countries. The status of each nation can be characterized by observing asbestos use and ARD frequency therein using a time window. Countries that supply technology for prevention of ARDs can be classified as donors and countries that receive these technologies as recipients. We suggest identification of three levels of core preventative technologies. Development of a common platform to gather and manage core preventative technologies will combine the strengths of donor countries and the needs of recipient countries.

Protective Immunity of Pichia pastoris-Expressed Recombinant Envelope Protein of Japanese Encephalitis Virus

  • Kwon, Woo-Taeg;Lee, Woo-Sik;Park, Pyo-Jam;Park, Tae-Kyu;Kang, Hyun
    • Journal of Microbiology and Biotechnology
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    • 제22권11호
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    • pp.1580-1587
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    • 2012
  • Japanese encephalitis virus (JEV) envelope (E) protein holds great promise for use in the development of a recombinant vaccine. Purified recombinant E (rE) protein may be useful for numerous clinical applications; however, there are limitations in using the Escherichia coli expression system for producing high-quality rE protein. Therefore, in this study, the yeast expression system was used to generate the rE protein. For protein production using the yeast system, the full-length JEV E gene was cloned into Pichia pastoris. SDS-PAGE and immunoblotting analysis demonstrated that the rE protein had a molecular mass of 58 kDa and was glycosylated. The predicted size of the mature unmodified E protein is 53 kDa, suggesting that post-translational modifications resulted in the higher molecular mass. The rE protein was purified to greater than 95% purity using combined ammonium sulfate precipitation and a SP-Sepharose Fast Flow column. This purified rE protein was evaluated for immunogenicity and protective efficacy in mice. The survival rates of mice immunized with the rE protein were significantly increased over that of Hyphantria cunea nuclear polyhedrosis virus E protein (HcE). Our results indicate that the rE protein expressed in the P. pastoris expression system holds great promise for use in the development of a subunit vaccine against JEV.

양돈작업자의 개인보호구 개발을 위한 소비자 인식조사 (Study on Consumer Awareness for the Development of Personal Protective Equipment for Hog Raisers)

  • 황영미;김경란;이경숙;채혜선
    • 한국환경보건학회지
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    • 제39권6호
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    • pp.522-531
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    • 2013
  • Objectives: A field survey was conducted in a hog-raising industry in order to help develop personal protective equipment for workers which would secure the safety and the health of these workers. The attempt by this study will help enhance safety in the livestock industry and contribute to the advancement of the industry. Method: The study first selected a total of 111 workers from the hog-raising industry as research participants and designed a survey with questions on general characteristics, indoor and outdoor working environments, how the workers would in practice wear or purchase the working clothes, what needs to be improved in these new working clothes, how much the workers would be likely to accept the working clothes and protective equipment, and lastly, conditions of the communicable disease control overgarment. The collected data underwent frequency analysis and cross analysis with SPSS 21.0. Result: The research targets' average age was 50 years. Work efficiency by environmental factor was normal, but all age groups had experience of accidents (79.3%). Major wounded parts were under elbow and under knee. Protective equipment most commonly worn was helmet (83.4%), gloves (98.2%) and boots (99.1%), and satisfaction with them was normal at 3.41. Working clothing most commonly worn was old clothing (31.8%) and everyday wear (17.6%) and satisfaction with it was low. Considering the improvement of working clothing, they required attached pouches, elasticity and deodorization. The acceptability of improved working clothing was high at 69.2%. Conclusion: After problems have been addressed in relevant future research, what has been learned from the concerned study will be referred to as a useful basic reference when the relevant field works to develop high-quality working clothing and protective equipment for workers in the hog-raising industry.

University/Hospital Collaborations to Promote Research and Evidence Based Practice in Clinical Environments

  • Griffiths, Rhonda
    • Perspectives in Nursing Science
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    • 제4권1호
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    • pp.19-25
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    • 2007
  • Systems and processes to provide clinical education to students of nursing have been established between universities and health facilities in all countries where nurse education is tertiary based. However, systems and processes to link nurse researchers based in universities to their clinical colleagues are less well developed. When collaborations are established they are frequently based on personal networks, and while the rhetoric of the organizations encourages these collaborations, they are largely unrecognised by senior administrators in health facilities. The research is frequently "invisible" and the clinician researchers usually do not have access to appropriate infrastructure and other resources that are required to support large projects that have the potential to change practice across organisations. This situation influences the focus and scope of nursing research and limits opportunities for clinicians to be engaged in the generation of professional knowledge. The University of Western Sydney (UWS) has taken a strategic approach to the development of collaborations for research and has linked with health services in Western Sydney to establish and maintain research centres and adjunct appointments. The partner organisations jointly fund the infrastructure of the centres which include a Professor, research assistant position(s) and administrative staff. Five Professors of Nursing have been appointed to positions in one of three nursing research centres. This paper describes the approach established by the School of Nursing at UWS to build collaborations with clinical areas to promote research. This approach could be adopted or adapted by other facilities.

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