• Interdisciplinary Bio Central
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• v.3 no.2
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• pp.6.1-6.3
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• 2011

Diabetes Mellitus (DM), often simply referred to as diabetes, has developed into a major health concern affecting more than 200 million people worldwide with approximately 4 million deaths per year attributed to the presence of the disease. Diabetes mellitus is categorized as Type 1 and Type 2, where Type 1 diabetes represents a lack of insulin production, and Type 2 diabetes is characterized by a relative lack of insulin receptor (i.e., decreased sensitivity to the effect of insulin) and cased by a complex interplay between genetic factors and environmental factors. Up to date, various studies on the pathology and mechanism in terms of genetic experiments have been conducted and approximately hundreds of genes were reported as diabetes mellitus associated genes. At this point, to support studies on the cause and mechanism of diabetes mellitus, an efficient database system to provide genetic variants related to diabetes mellitus is needed. DMBase is an integrated web-based genetic information resource for diabetes mellitus designed to service genomic variants, genes, and secondary information derived for diabetes mellitus genetics researchers. The current version of DMBase documents 754 genes with 3056 genetic variants and 66 pathways. It provides many effective search interfaces for retrieving diabetes mellitus and genetic information. A web interface for the DMBase is freely available at http://sysbio.kribb.re.kr/dmBase.

• Journal of The Korea Institute of Healthcare Architecture
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• v.13 no.2
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• pp.53-60
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• 2007

Various changes in medical environments including growing elderly population, chronic diseases, deepening competition among hospitals since opening to foreign medical service, economic strategy for improvement of profit system have caused hospitals to be specialized. In this backgrounds, the purpose of this study is to receive basic data for architectural planning on the spatial organization of outpatient department in general hospital. The results of this study were as follows; First, major changes of outpatient department in general hospital are composed of 'co-work in medical examination and treatment', 'decentralization of diagnosis and treatment(D/T)' and 'patient-oriented medical service'. Changes by co-work system include appearance of medical offices for co-work, activation of specialized clinics, grouping of E/T section for outpatient and various types of specialized centers. Second, the grouping of E/T sections means the modification of E/T system and organization in general hospitals, and a new spatial organization will be needed. Third, the types of specialized centers are getting varied. they are classified into several types including disease-resource, social stratum-resource, human organ-resource, health-resource, rehabilitation-resource, alternative medical center and so on.

• Parasites, Hosts and Diseases
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• v.59 no.5
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• pp.489-496
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• 2021

Ticks can transmit pathogenic bacteria, protozoa, and viruses to humans and animals. In this study, we investigated the microbiomes of Haemaphysalis longicornis according to sex and life stages. The Shannon index was significantly higher for nymphs than adult ticks. Principal coordinates analysis showed that the microbiome composition of female adult and male adult ticks were different. Notably, Coxiella-like bacterium (AB001519), known as a tick symbiont, was found in all nymphs and female adult ticks, but only one out of 4 male adult ticks had Coxiella-like bacterium (AB001519). In addition, Rickettsia rickettsii, Coxiella burnetii, and Anaplasma bovis were detected in this study.

• Korean Journal of Health Education and Promotion
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• v.27 no.2
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• pp.59-67
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• 2010

Objectives: As nationally qualified health education specialists were produced for the first time in 2010, there is a need to suggest opinions on its quality management by examining university curriculum for health education specialist and its education system and this is the main topic of paper. Results and conclusion: The results are as follows. First, it requires to provide a high-quality education continuously by introducing the certification system for universities which offer health education. Secondly, education content needs to be based on skill for health education specialist and more standardized curriculum should be developed. Thirdly, introduction of validity date for the health education specialist qualification is needed. Fourthly, it is desirable to introduce the academic credit bank system after effectively organizing the management system. Lastly, follow-up course for health education specialist needs to be introduced.

• Korean Journal of Pharmacognosy
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• v.47 no.3
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• pp.211-216
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• 2016

In the course of our continuing search for biologically active components from Korean medicinal plants, we isolated the main compound, luteolin 5-glucoside from aqueous fraction of Ajuga spectabilis. The structure was elucidated by the basis of $^1H$ and $^{13}C$ NMR and TOF ESI-MS data. Quantitative analysis of luteolin 5-glucoside was carried out on a XBridge C18 column ($S-5{\mu}m$, $4.6{\times}250mm$) with gradient elution composed of acetonitrile:water. The results exhibit that the average content of main compound in A. spectabilis were 0.048%. Oxidative stress plays a major role Alzheimer's disease (AD) and other neurodogenerative disease. AD is major health problem and there is currently no clinically accepted treatment to cure or stop its progression. Pretreatment with luteolin 5-glucoside markedly attenuated $H_2O_2$-induced cell viability loss in a dose-dependent manner. Luteolin 5-glucoside also inhibited the formation of intracellular reactive oxygen species in SH-SY5Y. The results suggest that luteolin 5-glucoside from A. spectabilis has protective effects against oxidative stress-induced cytotoxicity, which might be a potential therapeutic compound for treating and/or preventing neurodegenerative disease implicated with oxidative stress.

• The Korean Journal of Health Service Management
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• v.6 no.1
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• pp.247-258
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• 2012

Nurses are critical human resources for the hospitals. However, in Korean hospitals, human resource management practices for nurses are not well established, and nurses' turnover rates are very high. Although the causes and tasks for shortage of nurses are analyzed, suggestions for the specific ways of HRM management practices for hospital managers are rare. In this article, the management challenges for nurses are discussed, and high commitment human resources management model for nurses are suggested. And future research directions and topics are suggested.

• Journal of Family Resource Management and Policy Review
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• v.7 no.1
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• pp.23-39
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• 2003

The purpose of this study is to develop the life scale of the middle aged homemakers. The life scale are composed of spouse relation 8 items, child education relation 7 items, home economy relation 4 items, homework relation 3 items, selfish health relation 6 items, parent relation 3 items, and interest and social activity relation 4 items. The reliability coefficient of the development scale was Cronbach'α =.83 and the correlations of each demesne was high. For the better future life in this study, the middle aged homemakers are needed the improvement of conjugal relations, the child education, the health, the interest, and the enlargement of social relations. This life scale can help to evaluate their middle age, and to the planning of energetic healthful future, and useful to understanding characteristic and the developmental task of middle aged homemakers.

• Environmental and Resource Economics Review
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• v.11 no.1
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• pp.145-184
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• 2002

This paper analyzes the impact of imposing carbon tax on the Seoul economy to reduce Greenhouse Gas(GHG) emission. We construct the social accounting matrix of Seoul, specifying energy and transport sectors which is closely related to air pollution. Then, we formulated the computable general equilibrium (CGE) model of seoul and performed scenario analysis. The main result shows that the economic cost of GHG reduction is quite large but the health benefit is also considerable. It also suggests the importance of cost effective measures such as the development of new energy technology and the improvement of energy efficiency.

• Journal of Family Resource Management and Policy Review
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• v.11 no.4
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• pp.55-71
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• 2007

The purpose of this study was to explore a self-diagnostic indicator for measuring a healthy family by adopting the theme of "happiness", which has surfaced as the most interesting in many academic fields recently. Though the basic concept of a healthy family may be shared by everyone, the criterion of happiness varies from one family to another. Therefore, it is desirable that the tool be made in such a way that every member of the family can check their health from a holistic perspective, rather than diagnosing health and happiness from the perspective of professionals. So, this study was aimed at diagnosing a family by using a tool named GAMMA model, so each family member can recognize problems and find the best options to solve it. This study. has a significant meaning in that it has tried to diagnose families by introducing the GAMMA model into domestic science for the first time.

• Journal of Family Resource Management and Policy Review
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• v.5 no.1
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• pp.49-60
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• 2001

This research examined elderly’s quality of life(q/l). In order to explore the elderly’s q/l, it was conceptualized into 8 dimensions tapping macro and micro aspects of elderly’s life: physical & mental health, self-esteem, anxiety, social support, family solidarity, economic state, and physical environment. The primary purposes were to describe dimensions of q/l by the elderly’s sociodemographic variables. And the intercorrelations among q/l dimensions were examined and then the effects of q/l sub-dimensions on psychological well-being were analyzed by using multiple regression. Based on the data collected for 677 subjects residing in rural and urban areas, the basic issues hypothesized were explored. The findings appeared that the psychological well-being was a positive function of physical and mental health, self-esteem, social support, and economic state and a negative one of social anxiety, controlling for subjects’s sociodemographic variables.