• Title/Summary/Keyword: Health Platform

Search Result 497, Processing Time 0.021 seconds

Current status and prospects of blueberry genomics research (블루베리 유전체 연구현황 및 전망)

  • Kim, Jin Gook;Yun, Hae Keun
    • Journal of Plant Biotechnology
    • /
    • v.42 no.4
    • /
    • pp.336-341
    • /
    • 2015
  • Blueberry (Vaccinium spp.) is a bush that grows well at special cultural environments such as acid soil, high organic matter content, and a good drainage and aeration compared to other general crops. Blueberries are well known to contain high amounts of anthocyanins and phenolic compounds, resulting in high antioxidant activity that provides health benefits, and expanding the cultivation areas and consumer's demand in the worldwide. However, the full genome of blueberry has not been announced until now. Furthermore, the genomic analysis and transcriptome approaches are not so popular compare to major crops such as orange, apple, and grape. The aim of the review about blueberry genomic research is to establish the platform for setting blueberry breeding target, increasing proficiency of blueberry research, and making the practical cultivation techniques in Korea. The main topics in the blueberry genomic research including transcriptome, genetic mapping, and various markers are related with cold hardiness, chilling requirement, hot tolerance, anthocyanin content, and flavonoid synthesis pathway on various tissues like flower bud, leaf bud, shoot, root, and berry fruit. The review of the current status of blueberry genomic research will provide basic information to the breeders and researchers and will contribute to development of blueberry industry with sustainable productions and increase of blueberry consumption as new profitable crops in Korea.

Development of Real-time and Simultaneous Quantification of Volatile Organic Compounds in Ambient with SIFT-MS (Selected Ion Flow Tube-Mass Spectrometry) (선택적다중이온질량분석기를 이용한 대기 중 휘발성유기화합물 실시간 동시분석법 개발 및 적용)

  • Son, Hyun Dong;An, Joon Geon;Ha, Sung Yong;Kim, Gi Beum;Yim, Un Hyuk
    • Journal of Korean Society for Atmospheric Environment
    • /
    • v.34 no.3
    • /
    • pp.393-405
    • /
    • 2018
  • Volatile organic compounds (VOCs) are representative air pollutants due to their detrimental effects on human health and their role in formation of secondary organic aerosols. Assessments and monitoring programs of VOCs using periodic grab sampling like Tedlar bags, canisters, and sorbent traps provide limited information, often with delay times of days or weeks. Selected ion flow tube mass spectrometry (SIFT-MS) is an emerging analytical technique for the real-time quantification of VOCs in air. It relies on chemical ionization of the VOCs molecules in air introduced into helium carrier gas using $H_3O^+$, $NO^+$, and $O_2{^+}$ precursor ions. Real-time monitoring method of 60 VOCs in the ambient air was developed using TO-15 standard gas mixture. Calibration curves, method detection limit, and quantitation reproducibility of the target compounds were tested. Dynamic dilution system was used to dilute standard gas from 0.174 ppbv to 100 ppbv, where calibration curves showed good linearity with $r^2$> 0.95 in all target analytes. Limit of detection (LOD) all compounds were sub ppbv, and some halogenated compounds showed pptv levels. Seven consecutive analyses of target compounds showed good repeatability with relative standard deviation of less than 10%. One day monitoring of VOCs in ambient air was conducted in Geoje. Average concentration of target VOCs in Geoje were relatively lower than other regions, among which formaldehyde showed the highest concentration ($15.4{\pm}5.78ppbv$). SIFT-MS provided good temporal resolution data (1 data per 3.2 minute), which can be used for identifying ephemeral short-term event. It is expected that SIFT-MS will be a versatile monitoring platform for VOCs in ambient air.

Impact of Breed on the Fecal Microbiome of Dogs under the Same Dietary Condition

  • Reddy, Kondreddy Eswar;Kim, Hye-Ran;Jeong, Jin Young;So, Kyoung-Min;Lee, Seul;Ji, Sang Yun;Kim, Minji;Lee, Hyun-Jung;Lee, Sungdae;Kim, Ki-Hyun;Kim, Minseok
    • Journal of Microbiology and Biotechnology
    • /
    • v.29 no.12
    • /
    • pp.1947-1956
    • /
    • 2019
  • The gut microbiome influences the health and well-being of dogs. However, little is known about the impact of breed on the fecal microbiome composition in dogs. Therefore, we aimed to investigate the differences in the fecal microbiome in three breeds of dog fed and housed under the same conditions, namely eight Maltese (8.0 ± 0.1 years), eight Miniature Schnauzer (8.0 ± 0.0 years), and nine Poodle dogs (8.0 ± 0.0 years). Fresh fecal samples were collected from the dogs and used to extract metagenomic DNA. The composition of the fecal microbiome was evaluated by 16S rRNA gene amplicon sequencing on the MiSeq platform. A total of 840,501 sequences were obtained from the 25 fecal samples and classified as Firmicutes (32.3-97.3% of the total sequences), Bacteroidetes (0.1-62.6%), Actinobacteria (0.2-14.7%), Fusobacteria (0.0-5.7%), and Proteobacteria (0.0-5.1%). The relative abundance of Firmicutes was significantly lower in the Maltese dog breed than that in the other two breeds, while that of Fusobacteria was significantly higher in the Maltese than in the Miniature Schnauzer breed. At the genus level, the relative abundance of Streptococcus, Fusobacterium, Turicibacter, Succinivibrio, and Anaerobiospirillum differed significantly among the three dog breeds. These genera had no correlation with age, diet, sex, body weight, vaccination history, or parasite protection history. Within a breed, some of these genera had a correlation with at least one blood chemistry value. This study indicates that the composition of the fecal microbiome in dogs is affected by breed.

Research on Immune Enhancing Effect and Safety of Wasong (Orostachys japonicus) Extract: Study Protocol for a Single Center, Randomized, Double-blind, Placebo-controlled, Clinical Trial (와송 추출물의 면역기능 개선 효과 및 안전성 연구: 단일기관, 무작위배정, 이중눈가림, 위약대조 비교, 임상연구 프로토콜)

  • Choi, Jin Yong;Choi, Jun Yong;Lim, Hyun Woo;Kim, Jeong;Kim, So Yeon;Han, Chang Woo
    • Herbal Formula Science
    • /
    • v.25 no.2
    • /
    • pp.135-143
    • /
    • 2017
  • Objectives : This trial aimed to determine if Wasong (Orostachys japonicus) extract can enhance immune system and is safe enough to be approved as a health functional food. Methods : Total 62 people, aged 45 and older, will be recruited to participate in a randomized, double-blind, placebo-controlled clinical trial. This study will compare Wasong extract and placebo. Wasong group will take 1g of Wasong extract, once a day, for 8 weeks. Placebo group will take 1g of crystalline cellulose as placebo, once a day, for 8 weeks. Outcomes will be measured at the baseline, the end of 4th week, and 8th week. Primary outcomes are the ratio of NK cells/total lymphocytes and the ratio of T-helper cells/T-suppressor cells. Secondary outcomes are total white blood cell count, the ratio of neutrophils, lymphocytes, and monocytes in total leukocytes, the ratio of total T cells, T-helper cells, T-suppressor cells, and B cells to lymphocytes, the amount of blood IgM, IgG, IgA, and cytomegalovirus (CMV) IgG, and blood metabolite target &global analysis. Results : This trial was approved by institutional review board of Pusan National University Korean Medicine Hospital (registry number: 2016006), and registered in Clinical Research information Service, one of WHO International Clinical Trials Registry Platform (registry number: PRE20161006-002). Recruitment opened in February 2017 and is supposed to be completed by August 2017. The result is expected to be published by June 2018. Conclusion : This trial will provide clinical information to determine the efficacy and safety of Wasong in enhancing immune system of middle-aged and older people.

Analysis of Microbiota in Bellflower Root, Platycodon grandiflorum, Obtained from South Korea

  • Kim, Daeho;Hong, Sanghyun;Na, Hongjun;Chun, Jihwan;Guevarra, Robin B.;Kim, You-Tae;Ryu, Sangryeol;Kim, Hyeun Bum;Lee, Ju-Hoon
    • Journal of Microbiology and Biotechnology
    • /
    • v.28 no.4
    • /
    • pp.551-560
    • /
    • 2018
  • Bellflower root (Platycodon grandiflorum), which belongs to the Campanulaceae family, is a perennial grass that grows naturally in Korea, northeastern China, and Japan. Bellflower is widely consumed as both food and medicine owing to its high nutritional value and potential therapeutic effects. Since foodborne disease outbreaks often come from vegetables, understanding the public health risk of microorganisms on fresh vegetables is pivotal to predict and prevent foodborne disease outbreaks. We investigated the microbial communities on the bellflower root (n = 10). 16S rRNA gene amplicon sequencing targeting the V6-V9 regions of 16S rRNA genes was conducted via the 454-Titanium platform. The sequence quality was checked and phylogenetic assessments were performed using the RDP classifier implemented in QIIME with a bootstrap cutoff of 80%. Principal coordinate analysis was performed using the weighted Fast UniFrac distance. The average number of sequence reads generated per sample was 67,192 sequences. At the phylum level, bacterial communities from the bellflower root were composed primarily of Proteobacteria, Firmicutes, and Actinobacteria in March and September samples. Genera Serratia, Pseudomonas, and Pantoea comprised more than 54% of the total bellflower root bacteria. Principal coordinate analysis plots demonstrated that the microbial community of bellflower root in March samples was different from those in September samples. Potential pathogenic genera, such as Pantoea, were detected in bellflower root samples. Even though further studies will be required to determine if these species are associated with foodborne illness, our results indicate that the 16S rRNA gene-based sequencing approach can be used to detect pathogenic bacteria on fresh vegetables.

Assisted Outpatient Treatment and Crisis Intervention in USA and their Implications for Korea (미국의 외래치료명령제도 및 위기대응과 국내적 시사점)

  • Park, Inhwan;Han, Meekyung
    • The Korean Society of Law and Medicine
    • /
    • v.19 no.1
    • /
    • pp.23-80
    • /
    • 2018
  • Since the 1960s, the United States' (U.S.) deinstitutionalization policy has reinstated people with mental illness into communities. Unfortunately, when untreated, some people with psychiatric disorders become homeless, and some commit serious crimes during a psychological crisis. Assisted Outpatient Treatment (AOT), also known as Kendra's Law in New York and Laura's Law in California, provides treatment, services and support to people with mental illness in the community. AOT has repeatedly been found effective and is recognized as an evidence-based practice. The response to the mental health crisis (crisis intervention) in the U.S. has also been successful in preventing worsening mental illness and related criminality and other issues. This paper provides an opportunity to create a platform from which to learn how to successfully apply the AOT and crisis intervention of the U.S. to South Korea within the cultural and societal context when establishing social services for people with mental illness in South Korea's communities.

Implementation of a Remote Patient Monitoring System using Mobile Phones (모바일 폰을 이용한 원격 환자 관리 시스템의 구현)

  • Park, Hung-Bog;Seo, Jung-Hee
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.13 no.6
    • /
    • pp.1167-1174
    • /
    • 2009
  • In the monitoring of a patient in a sickroom, not only the physiologic and environmental data of the patient, which is automatically measured, but also the clinical data(clinical chart)of the patient, which is drew up by a doctor or nurse, are recognized as important data. However, since in the current environment of a sickroom, clinical data is collected being divided from the data that is automatically measured, the two data are used without an effective integration. This is because the integration of the two data is difficult due to their different collection times, which leads the reconstruction of clinical data to be remarkably uncertain. In order to solve these problems, a method to synchronize the continuous environmental data of a sickroom and clinical data is appearing as an important measure. In addition, the increase of use of small machines and the development of solutions based on wireless communications provide a communication platform to the developers of health care. Thus, this paper realizes a remote system for taking care of patients based on a web that uses mobile phones. That is, clinical data made by a nurse or doctor and the environmental data of a sick room comes to be collected by a collection module through a wireless sensor network. An observer can see clinical data and the environmental data of a sickroom through his/her mobile phone, integrating and storing his/her data into the database. Families of a patient can see clinical data made by hospital and the environment of the sick room of the patent through their computers or mobile phones outside the hospital. Through the system,hospital can provide better medical services to patients and their families.

The Effect of Dual-Task on Standing Postural Control in Persons With Chronic Stroke (만성 뇌졸중 환자의 기립 자세조절에 이중 과제가 미치는 영향)

  • Jeon, Hye-Won;Chung, Yi-Jung
    • Physical Therapy Korea
    • /
    • v.17 no.3
    • /
    • pp.20-30
    • /
    • 2010
  • This study examined whether any changes by mental task types on postural control in chronic stroke persons. Sixteen chronic stroke persons (mean age=53.75 yr) and sixteen age-and gender-matched healthy controls (mean age=54.44 yr) took part in this study. Participants randomly performed three different tasks on the stable and unstable surfaces. The no mental task was to stand while holding a 100 g weight in each hand, the arithmetic task (mental task) was to perform a silent 1-backwards counting while standing and holding a 100 g weight in each hand, and the simple task (mental task) was to stand and hold with both hands a tray (200 g) on which a glass filled with water has been placed. Sway path and sway velocity of the center of pressure (COP) were measured to assess standing postural control by task performance using the force platform. According to the results, in stroke group, total sway path and total sway velocity of COP was significantly decreased during arithmetic and simple task compared to no mental task on the stable surface (p<.05), and sway path (anteroposterior AP, mediolateral ML) of COP, total and sway velocity (AP, ML, total) of COP was significantly decreased during arithmetic and simple task compared to no mental task on the unstable surface (p<.05). Especially, sway path (AP, total) of COP and sway velocity (AP, ML, total) of COP was significantly decreased under the simple task when compared to the arithmetic task on the unstable surface (p<.05). In healthy control group, sway path (AP, ML, total) of COP and sway velocity (AP, ML, total) of COP was significantly decreased during arithmetic and simple task compared to no mental task on the stable and unstable surface (p<.05), and sway path (AP, total) of COP and sway velocity (AP, ML, total) of COP was significantly decreased under the simple task when compared to the arithmetic task on the unstable surface (p<.05). In conclusion, the findings of this study showed that arithmetic and simple task improved standing postural control for chronic stroke patients and the type of arithmetic and simple tasks were critical factor that reduced standing postural sway in dual-task conditions. Future research should determine whether dual-task conditions, including simple task, would be effective as a training program for standing postural control of stroke patients.

Strategic Approaches to Solid Ranking International Journals: KODISA Journals (국제저널 육성 방향과 전망: KODISA Journals를 중심으로)

  • Youn, Myoung-Kil;Kim, Dong-Ho;Lee, Jong-Ho;Hwang, Hee-Joong;Lee, Jung-Wan
    • Journal of Distribution Science
    • /
    • v.12 no.6
    • /
    • pp.5-13
    • /
    • 2014
  • Purpose - The purposes of this editorial review are twofold: firstly, to introduce the four flagship international journals of the Korea Distribution Science Association(KODISA): the Journal of Distribution Science(JDS), the Journal of Industrial Distribution & Business(JIDB), the East Asian Journal of Business Management(EAJBM), and the Journal of Asian Finance, Economics and Business(JAFEB), and secondly, to identify the direction of the KODISA journals and the roles and responsibilities of the editors of the KODISA journals. Research design, data, and methodology - To achieve the goals, firstly, this review paper addresses the current progress of the four KODISA journals: JDS, JIDB, EAJBM, and JAFEB. Secondly, this paper defines the aims and missions of the four KODISA journals. JDS publishes the articles of examining past, current, and emerging trends and concerns in the area of distribution science and economics, logistics and SCM, transportation, distribution channel management, distribution innovation and information technology, merchandising and procurement, distribution and marketing, consumer behavior, and manufacturing, wholesaling, and retailing. JDS publishes both quantitative and qualitative research as well as scholarly commentaries, case studies, book reviews and other types of reports relating to all aspects of distribution. JIDB publishes the articles of examining past, current, and emerging trends and concerns in the areas of industry and corporate behavior, industry policy making, industrial distribution and business, e-commerce, and service industry. EAJBM publishes empirical and theoretical research papers as well as scholarly commentaries, case studies, book reviews, and other types of reports relating to all aspects of East Asian business and economy. JAFEB publishes original research analysis and inquiry into the contemporary issues of finance, economics and business management in Asia, including Central Asia, East Asia, South Asia, Southeast Asia, and Middle East. The mission of JAFEB is to bring together the latest theoretical and empirical finance, economics and business management research in Asian markets. The audiences of the KODISA journals include higher education institutions, scholars, industry researchers and practitioners, scientists, economists, and policy makers throughout the world. The main mission of the KODISA journals is to provide an intellectual platform for international scholars, promote interdisciplinary studies in social sciences and economics, and become leading journals in the social science and economics category in the world. Thirdly, this paper addresses the current status of indexing in major databases of the KODISA journals, namely: Cabell's Directories, EBSCO, SCOPUS (Elsevier), and Social Sciences Citation Index® (SSCI, Thomson Reuters). Fourthly, this paper identifies the roles and responsibilities of the editors of the KODISA journals as the following: (1) Make sure that the journal be published in a timely manner and in international standards both in print and online versions. (2) Maintain the online homepage of the journal is always accessible to, and (3) Make sure that every article should go through a peer review process that meets international standards. Findings and conclusion - To accomplish the goals and missions of the KODISA journals, the editors of the KODISA journals must work together to publish high scholarly journals that meet international standards of journal publications.

A dose monitoring system for dental radiography

  • Lee, Chena;Lee, Sam-Sun;Kim, Jo-Eun;Symkhampha, Khanthaly;Lee, Woo-Jin;Huh, Kyung-Hoe;Yi, Won-Jin;Heo, Min-Suk;Choi, Soon-Chul;Yeom, Heon-Young
    • Imaging Science in Dentistry
    • /
    • v.46 no.2
    • /
    • pp.103-108
    • /
    • 2016
  • Purpose: The current study investigates the feasibility of a platform for a nationwide dose monitoring system for dental radiography. The essential elements for an unerring system are also assessed. Materials and Methods: An intraoral radiographic machine with 14 X-ray generators and five sensors, 45 panoramic radiographic machines, and 23 cone-beam computed tomography (CBCT) models used in Korean dental clinics were surveyed to investigate the type of dose report. A main server for storing the dose data from each radiographic machine was prepared. The dose report transfer pathways from the radiographic machine to the main sever were constructed. An effective dose calculation method was created based on the machine specifications and the exposure parameters of three intraoral radiographic machines, five panoramic radiographic machines, and four CBCTs. A viewing system was developed for both dentists and patients to view the calculated effective dose. Each procedure and the main server were integrated into one system. Results: The dose data from each type of radiographic machine was successfully transferred to the main server and converted into an effective dose. The effective dose stored in the main server is automatically connected to a viewing program for dentist and patient access. Conclusion: A patient radiation dose monitoring system is feasible for dental clinics. Future research in cooperation with clinicians, industry, and radiologists is needed to ensure format convertibility for an efficient dose monitoring system to monitor unexpected radiation dose.